pMSCV PIG (Puro IRES GFP empty vector) Citations (43)
Originally described in: Widespread shortening of 3'UTRs by alternative cleavage and polyadenylation activates oncogenes in cancer cells.Mayr C, Bartel DP Cell. 2009 Aug 21. 138(4):673-84. PubMed Journal
Articles Citing pMSCV PIG (Puro IRES GFP empty vector)
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| Rapid generation of microRNA sponges for microRNA inhibition. Kluiver J, Gibcus JH, Hettinga C, Adema A, Richter MK, Halsema N, Slezak-Prochazka I, Ding Y, Kroesen BJ, van den Berg A. PLoS One. 2012;7(1):e29275. doi: 10.1371/journal.pone.0029275. Epub 2012 Jan 6. PubMed |
| Generation of miRNA sponge constructs. Kluiver J, Slezak-Prochazka I, Smigielska-Czepiel K, Halsema N, Kroesen BJ, van den Berg A. Methods. 2012 Oct;58(2):113-7. doi: 10.1016/j.ymeth.2012.07.019. Epub 2012 Jul 23. PubMed |
| Design of a miRNA sponge for the miR-17 miRNA family as a therapeutic strategy against vulvar carcinoma. de Melo Maia B, Ling H, Monroig P, Ciccone M, Soares FA, Calin GA, Rocha RM. Mol Cell Probes. 2015 Dec;29(6):420-6. doi: 10.1016/j.mcp.2015.08.002. Epub 2015 Aug 20. PubMed |
| Targeting MYCN-Driven Transcription By BET-Bromodomain Inhibition. Henssen A, Althoff K, Odersky A, Beckers A, Koche R, Speleman F, Schafers S, Bell E, Nortmeyer M, Westermann F, De Preter K, Florin A, Heukamp L, Spruessel A, Astrahanseff K, Lindner S, Sadowski N, Schramm A, Astorgues-Xerri L, Riveiro ME, Eggert A, Cvitkovic E, Schulte JH. Clin Cancer Res. 2016 May 15;22(10):2470-81. doi: 10.1158/1078-0432.CCR-15-1449. Epub 2015 Dec 2. PubMed |
| Cleavage by Caspase 8 and Mitochondrial Membrane Association Activate the BH3-only Protein Bid during TRAIL-induced Apoptosis. Huang K, Zhang J, O'Neill KL, Gurumurthy CB, Quadros RM, Tu Y, Luo X. J Biol Chem. 2016 May 27;291(22):11843-51. doi: 10.1074/jbc.M115.711051. Epub 2016 Apr 6. PubMed |
| Protein arginylation regulates cellular stress response by stabilizing HSP70 and HSP40 transcripts. Deka K, Singh A, Chakraborty S, Mukhopadhyay R, Saha S. Cell Death Discov. 2016 Oct 3;2:16074. eCollection 2016. PubMed |
An Argonaute phosphorylation cycle promotes microRNA-mediated silencing.
Golden RJ, Chen B, Li T, Braun J, Manjunath H, Chen X, Wu J, Schmid V, Chang TC, Kopp F, Ramirez-Martinez A, Tagliabracci VS, Chen ZJ, Xie Y, Mendell JT.
Nature. 2017 Feb 9;542(7640):197-202. doi: 10.1038/nature21025. Epub 2017 Jan 23.
PubMed
Associated Plasmids |
| Alternate splicing of transcripts shape macrophage response to Mycobacterium tuberculosis infection. Kalam H, Fontana MF, Kumar D. PLoS Pathog. 2017 Mar 3;13(3):e1006236. doi: 10.1371/journal.ppat.1006236. eCollection 2017 Mar. PubMed |
| Cyclin C regulates adipogenesis by stimulating transcriptional activity of CCAAT/enhancer-binding protein alpha. Song Z, Xiaoli AM, Zhang Q, Zhang Y, Yang EST, Wang S, Chang R, Zhang ZD, Yang G, Strich R, Pessin JE, Yang F. J Biol Chem. 2017 May 26;292(21):8918-8932. doi: 10.1074/jbc.M117.776229. Epub 2017 Mar 28. PubMed |
| Folate-dependent methylation of septins governs ciliogenesis during neural tube closure. Toriyama M, Toriyama M, Wallingford JB, Finnell RH. FASEB J. 2017 Aug;31(8):3622-3635. doi: 10.1096/fj.201700092R. Epub 2017 Apr 21. PubMed |
| The cell polarity protein Scrib functions as a tumor suppressor in liver cancer. Kapil S, Sharma BK, Patil M, Elattar S, Yuan J, Hou SX, Kolhe R, Satyanarayana A. Oncotarget. 2017 Apr 18;8(16):26515-26531. doi: 10.18632/oncotarget.15713. PubMed |
Oncogenic K-Ras upregulates ITGA6 expression via FOSL1 to induce anoikis resistance and synergizes with alphaV-Class integrins to promote EMT.
Zhang K, Myllymaki SM, Gao P, Devarajan R, Kytola V, Nykter M, Wei GH, Manninen A.
Oncogene. 2017 Oct 12;36(41):5681-5694. doi: 10.1038/onc.2017.177. Epub 2017 Jun 12.
PubMed
Associated Plasmids |
| Dissecting Regulatory Mechanisms Using Mouse Fetal Liver-Derived Erythroid Cells. McIver SC, Hewitt KJ, Gao X, Mehta C, Zhang J, Bresnick EH. Methods Mol Biol. 2018;1698:67-89. doi: 10.1007/978-1-4939-7428-3_4. PubMed |
| Hit-and-run epigenetic editing prevents senescence entry in primary breast cells from healthy donors. Saunderson EA, Stepper P, Gomm JJ, Hoa L, Morgan A, Allen MD, Jones JL, Gribben JG, Jurkowski TP, Ficz G. Nat Commun. 2017 Nov 13;8(1):1450. doi: 10.1038/s41467-017-01078-2. PubMed |
| Cytoplasmic Linker Protein CLIP170 Negatively Regulates TLR4 Signaling by Targeting the TLR Adaptor Protein TIRAP. Jakka P, Bhargavi B, Namani S, Murugan S, Splitter G, Radhakrishnan G. J Immunol. 2018 Jan 15;200(2):704-714. doi: 10.4049/jimmunol.1601559. Epub 2017 Dec 8. PubMed |
METTL14 Inhibits Hematopoietic Stem/Progenitor Differentiation and Promotes Leukemogenesis via mRNA m(6)A Modification.
Weng H, Huang H, Wu H, Qin X, Zhao BS, Dong L, Shi H, Skibbe J, Shen C, Hu C, Sheng Y, Wang Y, Wunderlich M, Zhang B, Dore LC, Su R, Deng X, Ferchen K, Li C, Sun M, Lu Z, Jiang X, Marcucci G, Mulloy JC, Yang J, Qian Z, Wei M, He C, Chen J.
Cell Stem Cell. 2018 Feb 1;22(2):191-205.e9. doi: 10.1016/j.stem.2017.11.016. Epub 2017 Dec 28.
PubMed
Associated Plasmids |
| The miR-17/92 cluster is involved in the molecular etiology of the SCLL syndrome driven by the BCR-FGFR1 chimeric kinase. Hu T, Chong Y, Qin H, Kitamura E, Chang CS, Silva J, Ren M, Cowell JK. Oncogene. 2018 Apr;37(14):1926-1938. doi: 10.1038/s41388-017-0091-1. Epub 2018 Jan 25. PubMed |
| RHOA G17V Induces T Follicular Helper Cell Specification and Promotes Lymphomagenesis. Cortes JR, Ambesi-Impiombato A, Couronne L, Quinn SA, Kim CS, da Silva Almeida AC, West Z, Belver L, Martin MS, Scourzic L, Bhagat G, Bernard OA, Ferrando AA, Palomero T. Cancer Cell. 2018 Feb 12;33(2):259-273.e7. doi: 10.1016/j.ccell.2018.01.001. Epub 2018 Feb 2. PubMed |
| Identification and characterization of a novel adenomatous polyposis coli mutation in adult pancreatoblastoma. Yamaguchi S, Fujii T, Izumi Y, Fukumura Y, Han M, Yamaguchi H, Akita T, Yamashita C, Kato S, Sekiya T. Oncotarget. 2018 Jan 6;9(12):10818-10827. doi: 10.18632/oncotarget.24017. eCollection 2018 Feb 13. PubMed |
| miR-339 Promotes Development of Stem Cell Leukemia/Lymphoma Syndrome via Downregulation of the BCL2L11 and BAX Proapoptotic Genes. Hu T, Chong Y, Lu S, Wang R, Qin H, Silva J, Kitamura E, Chang CS, Hawthorn L, Cowell JK. Cancer Res. 2018 Jul 1;78(13):3522-3531. doi: 10.1158/0008-5472.CAN-17-4049. Epub 2018 May 7. PubMed |
| HER2 Amplification in Tumors Activates PI3K/Akt Signaling Independent of HER3. Ruiz-Saenz A, Dreyer C, Campbell MR, Steri V, Gulizia N, Moasser MM. Cancer Res. 2018 Jul 1;78(13):3645-3658. doi: 10.1158/0008-5472.CAN-18-0430. Epub 2018 May 14. PubMed |
| A Split Transcriptional Repressor That Links Protein Solubility to an Orthogonal Genetic Circuit. Zeng Y, Jones AM, Thomas EE, Nassif B, Silberg JJ, Segatori L. ACS Synth Biol. 2018 Sep 21;7(9):2126-2138. doi: 10.1021/acssynbio.8b00129. Epub 2018 Aug 23. PubMed |
| PP4 deficiency leads to DNA replication stress that impairs immunoglobulin class switch efficiency. Chen MY, Hsu WC, Hsu SC, Yang YS, Chuang TH, Lin WJ, Tan TH, Su YW. Cell Death Differ. 2018 Sep 20. pii: 10.1038/s41418-018-0199-z. doi: 10.1038/s41418-018-0199-z. PubMed |
| Heterogeneous Responses of Hematopoietic Stem Cells to Inflammatory Stimuli Are Altered with Age. Mann M, Mehta A, de Boer CG, Kowalczyk MS, Lee K, Haldeman P, Rogel N, Knecht AR, Farouq D, Regev A, Baltimore D. Cell Rep. 2018 Dec 11;25(11):2992-3005.e5. doi: 10.1016/j.celrep.2018.11.056. PubMed |
| Arginylation regulates adipogenesis by regulating expression of PPARgamma at transcript and protein level. Singh A, Borah AK, Deka K, Gogoi AP, Verma K, Barah P, Saha S. Biochim Biophys Acta Mol Cell Biol Lipids. 2019 Apr;1864(4):596-607. doi: 10.1016/j.bbalip.2018.12.015. Epub 2018 Dec 28. PubMed |
| Loss of Nuclear TDP-43 Is Associated with Decondensation of LINE Retrotransposons. Liu EY, Russ J, Cali CP, Phan JM, Amlie-Wolf A, Lee EB. Cell Rep. 2019 Apr 30;27(5):1409-1421.e6. doi: 10.1016/j.celrep.2019.04.003. PubMed |
| The long noncoding RNA CHROME regulates cholesterol homeostasis in primate. Hennessy EJ, van Solingen C, Scacalossi KR, Ouimet M, Afonso MS, Prins J, Koelwyn GJ, Sharma M, Ramkhelawon B, Carpenter S, Busch A, Chernogubova E, Matic LP, Hedin U, Maegdefessel L, Caffrey BE, Hussein MA, Ricci EP, Temel RE, Garabedian MJ, Berger JS, Vickers KC, Kanke M, Sethupathy P, Teupser D, Holdt LM, Moore KJ. Nat Metab. 2019 Jan;1(1):98-110. doi: 10.1038/s42255-018-0004-9. Epub 2018 Dec 3. PubMed |
| Investigating the duality of Inpp4b function in the cellular transformation of mouse fibroblasts. Mangialardi EM, Chen K, Salmon B, Vacher J, Salmena L. Oncotarget. 2019 Oct 29;10(59):6378-6390. doi: 10.18632/oncotarget.27293. eCollection 2019 Oct 29. PubMed |
| Sterile alpha-motif domain requirement for cellular signaling and survival. Ray S, Chee L, Matson DR, Palermo NY, Bresnick EH, Hewitt KJ. J Biol Chem. 2020 May 15;295(20):7113-7125. doi: 10.1074/jbc.RA119.011895. Epub 2020 Apr 2. PubMed |
| Estrogen Reverses HDAC Inhibitor-Mediated Repression of Aicda and Class-Switching in Antibody and Autoantibody Responses by Downregulation of miR-26a. Casali P, Shen T, Xu Y, Qiu Z, Chupp DP, Im J, Xu Z, Zan H. Front Immunol. 2020 Mar 24;11:491. doi: 10.3389/fimmu.2020.00491. eCollection 2020. PubMed |
| Live cell imaging and proteomic profiling of endogenous NEAT1 lncRNA by CRISPR/Cas9-mediated knock-in. Chen B, Deng S, Ge T, Ye M, Yu J, Lin S, Ma W, Songyang Z. Protein Cell. 2020 Sep;11(9):641-660. doi: 10.1007/s13238-020-00706-w. Epub 2020 May 26. PubMed |
| High-Resolution In Vivo Identification of miRNA Targets by Halo-Enhanced Ago2 Pull-Down. Li X, Pritykin Y, Concepcion CP, Lu Y, La Rocca G, Zhang M, King B, Cook PJ, Au YW, Popow O, Paulo JA, Otis HG, Mastroleo C, Ogrodowski P, Schreiner R, Haigis KM, Betel D, Leslie CS, Ventura A. Mol Cell. 2020 Jul 2;79(1):167-179.e11. doi: 10.1016/j.molcel.2020.05.009. Epub 2020 Jun 3. PubMed |
| The long non-coding RNA LUCAT1 is a negative feedback regulator of interferon responses in humans. Agarwal S, Vierbuchen T, Ghosh S, Chan J, Jiang Z, Kandasamy RK, Ricci E, Fitzgerald KA. Nat Commun. 2020 Dec 11;11(1):6348. doi: 10.1038/s41467-020-20165-5. PubMed |
| Signatures of host-pathogen evolutionary conflict reveal MISTR-A conserved MItochondrial STress Response network. Sorouri M, Chang T, Jesudhasan P, Pinkham C, Elde NC, Hancks DC. PLoS Biol. 2020 Dec 28;18(12):e3001045. doi: 10.1371/journal.pbio.3001045. eCollection 2020 Dec. PubMed |
| E2F6 initiates stable epigenetic silencing of germline genes during embryonic development. Dahlet T, Truss M, Frede U, Al Adhami H, Bardet AF, Dumas M, Vallet J, Chicher J, Hammann P, Kottnik S, Hansen P, Luz U, Alvarez G, Auclair G, Hecht J, Robinson PN, Hagemeier C, Weber M. Nat Commun. 2021 Jun 11;12(1):3582. doi: 10.1038/s41467-021-23596-w. PubMed |
| Epigenetic Modulation of Class-Switch DNA Recombination to IgA by miR-146a Through Downregulation of Smad2, Smad3 and Smad4. Casali P, Li S, Morales G, Daw CC, Chupp DP, Fisher AD, Zan H. Front Immunol. 2021 Nov 16;12:761450. doi: 10.3389/fimmu.2021.761450. eCollection 2021. PubMed |
| Expression analysis and function of mitochondrial genome-encoded microRNAs. Kuthethur R, Shukla V, Mallya S, Adiga D, Kabekkodu SP, Ramachandra L, Saxena PUP, Satyamoorthy K, Chakrabarty S. J Cell Sci. 2022 Apr 15;135(8):jcs258937. doi: 10.1242/jcs.258937. Epub 2022 Apr 19. PubMed |
| Functional requirements for a Samd14-capping protein complex in stress erythropoiesis. Ray S, Chee L, Zhou Y, Schaefer MA, Naldrett MJ, Alvarez S, Woods NT, Hewitt KJ. Elife. 2022 Jun 17;11:e76497. doi: 10.7554/eLife.76497. PubMed |
| Combined inhibition of aurora kinases and Bcl-xL induces apoptosis through select BH3-only proteins. Li J, Chen CH, O'Neill KL, Fousek-Schuller VJ, Black AR, Black JD, Zhang J, Luo X. J Biol Chem. 2023 Feb;299(2):102875. doi: 10.1016/j.jbc.2023.102875. Epub 2023 Jan 6. PubMed |
| Defining A Cohort of Anemia-Activated Cis-Elements Reveals a Mechanism Promoting Erythroid Precursor Function. Zhou Y, Dogiparthi VR, Ray S, Schaefer M, Harris HL, Rowley MJ, Hewitt KJ. Blood Adv. 2023 Feb 21:bloodadvances.2022009163. doi: 10.1182/bloodadvances.2022009163. PubMed |
| Mammalian pumilio proteins control cellular morphology, migration, and adhesion. Sternburg EL, Lillibridge JJ, Phandthong R, Karginov FV. Sci Rep. 2023 Feb 21;13(1):3002. doi: 10.1038/s41598-023-30004-4. PubMed |
| Mapping the T cell repertoire to a complex gut bacterial community. Nagashima K, Zhao A, Atabakhsh K, Bae M, Blum JE, Weakley A, Jain S, Meng X, Cheng AG, Wang M, Higginbottom S, Dimas A, Murugkar P, Sattely ES, Moon JJ, Balskus EP, Fischbach MA. Nature. 2023 Sep;621(7977):162-170. doi: 10.1038/s41586-023-06431-8. Epub 2023 Aug 16. PubMed |
| Outer membrane protein 25 of Brucella suppresses TLR-mediated expression of proinflammatory cytokines through degradation of TLRs and adaptor proteins. Murugan S, Nandi BR, Mazumdar V, Joshi K, Nandini P, Namani S, Jakka P, Radhakrishnan GK. J Biol Chem. 2023 Nov;299(11):105309. doi: 10.1016/j.jbc.2023.105309. Epub 2023 Sep 29. PubMed |
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