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pMSCV PIG (Puro IRES GFP empty vector) Citations (31)

Plasmid Article: Widespread shortening of 3'UTRs by alternative cleavage and polyadenylation activates oncogenes in cancer cells.
Mayr C, Bartel DP Cell. 2009 Aug 21. 138(4):673-84.
PubMed Journal

Articles Citing pMSCV PIG (Puro IRES GFP empty vector)

Rapid generation of microRNA sponges for microRNA inhibition. Kluiver J, Gibcus JH, Hettinga C, Adema A, Richter MK, Halsema N, Slezak-Prochazka I, Ding Y, Kroesen BJ, van den Berg A. PLoS One. 2012;7(1):e29275. doi: 10.1371/journal.pone.0029275. Epub 2012 Jan 6. PubMed
Generation of miRNA sponge constructs. Kluiver J, Slezak-Prochazka I, Smigielska-Czepiel K, Halsema N, Kroesen BJ, van den Berg A. Methods. 2012 Oct;58(2):113-7. doi: 10.1016/j.ymeth.2012.07.019. Epub 2012 Jul 23. PubMed
Design of a miRNA sponge for the miR-17 miRNA family as a therapeutic strategy against vulvar carcinoma. de Melo Maia B, Ling H, Monroig P, Ciccone M, Soares FA, Calin GA, Rocha RM. Mol Cell Probes. 2015 Dec;29(6):420-6. doi: 10.1016/j.mcp.2015.08.002. Epub 2015 Aug 20. PubMed
Targeting MYCN-Driven Transcription By BET-Bromodomain Inhibition. Henssen A, Althoff K, Odersky A, Beckers A, Koche R, Speleman F, Schafers S, Bell E, Nortmeyer M, Westermann F, De Preter K, Florin A, Heukamp L, Spruessel A, Astrahanseff K, Lindner S, Sadowski N, Schramm A, Astorgues-Xerri L, Riveiro ME, Eggert A, Cvitkovic E, Schulte JH. Clin Cancer Res. 2016 May 15;22(10):2470-81. doi: 10.1158/1078-0432.CCR-15-1449. Epub 2015 Dec 2. PubMed
Cleavage by Caspase 8 and Mitochondrial Membrane Association Activate the BH3-only Protein Bid during TRAIL-induced Apoptosis. Huang K, Zhang J, O'Neill KL, Gurumurthy CB, Quadros RM, Tu Y, Luo X. J Biol Chem. 2016 May 27;291(22):11843-51. doi: 10.1074/jbc.M115.711051. Epub 2016 Apr 6. PubMed
Protein arginylation regulates cellular stress response by stabilizing HSP70 and HSP40 transcripts. Deka K, Singh A, Chakraborty S, Mukhopadhyay R, Saha S. Cell Death Discov. 2016 Oct 3;2:16074. eCollection 2016. PubMed
An Argonaute phosphorylation cycle promotes microRNA-mediated silencing. Golden RJ, Chen B, Li T, Braun J, Manjunath H, Chen X, Wu J, Schmid V, Chang TC, Kopp F, Ramirez-Martinez A, Tagliabracci VS, Chen ZJ, Xie Y, Mendell JT. Nature. 2017 Feb 9;542(7640):197-202. doi: 10.1038/nature21025. Epub 2017 Jan 23. PubMed

Associated Plasmids

Alternate splicing of transcripts shape macrophage response to Mycobacterium tuberculosis infection. Kalam H, Fontana MF, Kumar D. PLoS Pathog. 2017 Mar 3;13(3):e1006236. doi: 10.1371/journal.ppat.1006236. eCollection 2017 Mar. PubMed
Cyclin C regulates adipogenesis by stimulating transcriptional activity of CCAAT/enhancer-binding protein alpha. Song Z, Xiaoli AM, Zhang Q, Zhang Y, Yang EST, Wang S, Chang R, Zhang ZD, Yang G, Strich R, Pessin JE, Yang F. J Biol Chem. 2017 May 26;292(21):8918-8932. doi: 10.1074/jbc.M117.776229. Epub 2017 Mar 28. PubMed
Folate-dependent methylation of septins governs ciliogenesis during neural tube closure. Toriyama M, Toriyama M, Wallingford JB, Finnell RH. FASEB J. 2017 Aug;31(8):3622-3635. doi: 10.1096/fj.201700092R. Epub 2017 Apr 21. PubMed
The cell polarity protein Scrib functions as a tumor suppressor in liver cancer. Kapil S, Sharma BK, Patil M, Elattar S, Yuan J, Hou SX, Kolhe R, Satyanarayana A. Oncotarget. 2017 Apr 18;8(16):26515-26531. doi: 10.18632/oncotarget.15713. PubMed
Oncogenic K-Ras upregulates ITGA6 expression via FOSL1 to induce anoikis resistance and synergizes with alphaV-Class integrins to promote EMT. Zhang K, Myllymaki SM, Gao P, Devarajan R, Kytola V, Nykter M, Wei GH, Manninen A. Oncogene. 2017 Oct 12;36(41):5681-5694. doi: 10.1038/onc.2017.177. Epub 2017 Jun 12. PubMed

Associated Plasmids

Dissecting Regulatory Mechanisms Using Mouse Fetal Liver-Derived Erythroid Cells. McIver SC, Hewitt KJ, Gao X, Mehta C, Zhang J, Bresnick EH. Methods Mol Biol. 2018;1698:67-89. doi: 10.1007/978-1-4939-7428-3_4. PubMed
Hit-and-run epigenetic editing prevents senescence entry in primary breast cells from healthy donors. Saunderson EA, Stepper P, Gomm JJ, Hoa L, Morgan A, Allen MD, Jones JL, Gribben JG, Jurkowski TP, Ficz G. Nat Commun. 2017 Nov 13;8(1):1450. doi: 10.1038/s41467-017-01078-2. PubMed
Cytoplasmic Linker Protein CLIP170 Negatively Regulates TLR4 Signaling by Targeting the TLR Adaptor Protein TIRAP. Jakka P, Bhargavi B, Namani S, Murugan S, Splitter G, Radhakrishnan G. J Immunol. 2018 Jan 15;200(2):704-714. doi: 10.4049/jimmunol.1601559. Epub 2017 Dec 8. PubMed
METTL14 Inhibits Hematopoietic Stem/Progenitor Differentiation and Promotes Leukemogenesis via mRNA m(6)A Modification. Weng H, Huang H, Wu H, Qin X, Zhao BS, Dong L, Shi H, Skibbe J, Shen C, Hu C, Sheng Y, Wang Y, Wunderlich M, Zhang B, Dore LC, Su R, Deng X, Ferchen K, Li C, Sun M, Lu Z, Jiang X, Marcucci G, Mulloy JC, Yang J, Qian Z, Wei M, He C, Chen J. Cell Stem Cell. 2018 Feb 1;22(2):191-205.e9. doi: 10.1016/j.stem.2017.11.016. Epub 2017 Dec 28. PubMed

Associated Plasmids

The miR-17/92 cluster is involved in the molecular etiology of the SCLL syndrome driven by the BCR-FGFR1 chimeric kinase. Hu T, Chong Y, Qin H, Kitamura E, Chang CS, Silva J, Ren M, Cowell JK. Oncogene. 2018 Apr;37(14):1926-1938. doi: 10.1038/s41388-017-0091-1. Epub 2018 Jan 25. PubMed
RHOA G17V Induces T Follicular Helper Cell Specification and Promotes Lymphomagenesis. Cortes JR, Ambesi-Impiombato A, Couronne L, Quinn SA, Kim CS, da Silva Almeida AC, West Z, Belver L, Martin MS, Scourzic L, Bhagat G, Bernard OA, Ferrando AA, Palomero T. Cancer Cell. 2018 Feb 12;33(2):259-273.e7. doi: 10.1016/j.ccell.2018.01.001. Epub 2018 Feb 2. PubMed
Identification and characterization of a novel adenomatous polyposis coli mutation in adult pancreatoblastoma. Yamaguchi S, Fujii T, Izumi Y, Fukumura Y, Han M, Yamaguchi H, Akita T, Yamashita C, Kato S, Sekiya T. Oncotarget. 2018 Jan 6;9(12):10818-10827. doi: 10.18632/oncotarget.24017. eCollection 2018 Feb 13. PubMed
miR-339 Promotes Development of Stem Cell Leukemia/Lymphoma Syndrome via Downregulation of the BCL2L11 and BAX Proapoptotic Genes. Hu T, Chong Y, Lu S, Wang R, Qin H, Silva J, Kitamura E, Chang CS, Hawthorn L, Cowell JK. Cancer Res. 2018 Jul 1;78(13):3522-3531. doi: 10.1158/0008-5472.CAN-17-4049. Epub 2018 May 7. PubMed
HER2 Amplification in Tumors Activates PI3K/Akt Signaling Independent of HER3. Ruiz-Saenz A, Dreyer C, Campbell MR, Steri V, Gulizia N, Moasser MM. Cancer Res. 2018 Jul 1;78(13):3645-3658. doi: 10.1158/0008-5472.CAN-18-0430. Epub 2018 May 14. PubMed
A Split Transcriptional Repressor That Links Protein Solubility to an Orthogonal Genetic Circuit. Zeng Y, Jones AM, Thomas EE, Nassif B, Silberg JJ, Segatori L. ACS Synth Biol. 2018 Sep 21;7(9):2126-2138. doi: 10.1021/acssynbio.8b00129. Epub 2018 Aug 23. PubMed
PP4 deficiency leads to DNA replication stress that impairs immunoglobulin class switch efficiency. Chen MY, Hsu WC, Hsu SC, Yang YS, Chuang TH, Lin WJ, Tan TH, Su YW. Cell Death Differ. 2018 Sep 20. pii: 10.1038/s41418-018-0199-z. doi: 10.1038/s41418-018-0199-z. PubMed
Heterogeneous Responses of Hematopoietic Stem Cells to Inflammatory Stimuli Are Altered with Age. Mann M, Mehta A, de Boer CG, Kowalczyk MS, Lee K, Haldeman P, Rogel N, Knecht AR, Farouq D, Regev A, Baltimore D. Cell Rep. 2018 Dec 11;25(11):2992-3005.e5. doi: 10.1016/j.celrep.2018.11.056. PubMed
Arginylation regulates adipogenesis by regulating expression of PPARgamma at transcript and protein level. Singh A, Borah AK, Deka K, Gogoi AP, Verma K, Barah P, Saha S. Biochim Biophys Acta Mol Cell Biol Lipids. 2019 Apr;1864(4):596-607. doi: 10.1016/j.bbalip.2018.12.015. Epub 2018 Dec 28. PubMed
Loss of Nuclear TDP-43 Is Associated with Decondensation of LINE Retrotransposons. Liu EY, Russ J, Cali CP, Phan JM, Amlie-Wolf A, Lee EB. Cell Rep. 2019 Apr 30;27(5):1409-1421.e6. doi: 10.1016/j.celrep.2019.04.003. PubMed
The long noncoding RNA CHROME regulates cholesterol homeostasis in primate. Hennessy EJ, van Solingen C, Scacalossi KR, Ouimet M, Afonso MS, Prins J, Koelwyn GJ, Sharma M, Ramkhelawon B, Carpenter S, Busch A, Chernogubova E, Matic LP, Hedin U, Maegdefessel L, Caffrey BE, Hussein MA, Ricci EP, Temel RE, Garabedian MJ, Berger JS, Vickers KC, Kanke M, Sethupathy P, Teupser D, Holdt LM, Moore KJ. Nat Metab. 2019 Jan;1(1):98-110. doi: 10.1038/s42255-018-0004-9. Epub 2018 Dec 3. PubMed
Investigating the duality of Inpp4b function in the cellular transformation of mouse fibroblasts. Mangialardi EM, Chen K, Salmon B, Vacher J, Salmena L. Oncotarget. 2019 Oct 29;10(59):6378-6390. doi: 10.18632/oncotarget.27293. eCollection 2019 Oct 29. PubMed
Sterile alpha-motif domain requirement for cellular signaling and survival. Ray S, Chee L, Matson DR, Palermo NY, Bresnick EH, Hewitt KJ. J Biol Chem. 2020 May 15;295(20):7113-7125. doi: 10.1074/jbc.RA119.011895. Epub 2020 Apr 2. PubMed
Estrogen Reverses HDAC Inhibitor-Mediated Repression of Aicda and Class-Switching in Antibody and Autoantibody Responses by Downregulation of miR-26a. Casali P, Shen T, Xu Y, Qiu Z, Chupp DP, Im J, Xu Z, Zan H. Front Immunol. 2020 Mar 24;11:491. doi: 10.3389/fimmu.2020.00491. eCollection 2020. PubMed
Live cell imaging and proteomic profiling of endogenous NEAT1 lncRNA by CRISPR/Cas9-mediated knock-in. Chen B, Deng S, Ge T, Ye M, Yu J, Lin S, Ma W, Songyang Z. Protein Cell. 2020 Sep;11(9):641-660. doi: 10.1007/s13238-020-00706-w. Epub 2020 May 26. PubMed

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