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Hsp90 HA Citations (21)

Originally described in: Dynamic activation of endothelial nitric oxide synthase by Hsp90.
Garcia-Cardena G, Fan R, Shah V, Sorrentino R, Cirino G, Papapetropoulos A, Sessa WC Nature. 1998 Apr 23. 392(6678):821-4.
PubMed Journal

Articles Citing Hsp90 HA

Molecular mechanism of 17-allylamino-17-demethoxygeldanamycin (17-AAG)-induced AXL receptor tyrosine kinase degradation. Krishnamoorthy GP, Guida T, Alfano L, Avilla E, Santoro M, Carlomagno F, Melillo RM. J Biol Chem. 2013 Jun 14;288(24):17481-94. doi: 10.1074/jbc.M112.439422. Epub 2013 Apr 29. PubMed

Associated Plasmids

HSP90 protects the human T-cell leukemia virus type 1 (HTLV-1) tax oncoprotein from proteasomal degradation to support NF-kappaB activation and HTLV-1 replication. Gao L, Harhaj EW. J Virol. 2013 Dec;87(24):13640-54. doi: 10.1128/JVI.02006-13. Epub 2013 Oct 9. PubMed
Overexpression of the transcriptional repressor complex BCL-6/BCoR leads to nuclear aggregates distinct from classical aggresomes. Buchberger E, El Harchi M, Payrhuber D, Zommer A, Schauer D, Simonitsch-Klupp I, Bilban M, Brostjan C. PLoS One. 2013 Oct 11;8(10):e76845. doi: 10.1371/journal.pone.0076845. eCollection 2013. PubMed
Defective Tibetan PHD2 binding to p23 links high altitude adaption to altered oxygen sensing. Song D, Li LS, Arsenault PR, Tan Q, Bigham AW, Heaton-Johnson KJ, Master SR, Lee FS. J Biol Chem. 2014 May 23;289(21):14656-65. doi: 10.1074/jbc.M113.541227. Epub 2014 Apr 7. PubMed
BAG2 Gene-mediated Regulation of PINK1 Protein Is Critical for Mitochondrial Translocation of PARKIN and Neuronal Survival. Qu D, Hage A, Don-Carolis K, Huang E, Joselin A, Safarpour F, Marcogliese PC, Rousseaux MW, Hewitt SJ, Huang T, Im DS, Callaghan S, Dewar-Darch D, Figeys D, Slack RS, Park DS. J Biol Chem. 2015 Dec 18;290(51):30441-52. doi: 10.1074/jbc.M115.677815. Epub 2015 Nov 4. PubMed
Stress-induced phosphoprotein-1 maintains the stability of JAK2 in cancer cells. Tsai CL, Chao A, Jung SM, Tsai CN, Lin CY, Chen SH, Sue SC, Wang TH, Wang HS, Lai CH. Oncotarget. 2016 Aug 2;7(31):50548-50563. doi: 10.18632/oncotarget.10500. PubMed
Stabilization of Notch1 by the Hsp90 Chaperone is Crucial for T-Cell Leukemogenesis. Wang Z, Hu Y, Xiao D, Wang J, Liu C, Xu Y, Shi X, Jiang P, Huang L, Li P, Liu H, Qing G. Clin Cancer Res. 2017 Jul 15;23(14):3834-3846. doi: 10.1158/1078-0432.CCR-16-2880. Epub 2017 Jan 31. PubMed
Single-walled carbon nanotubes (SWCNTs) inhibit heat shock protein 90 (HSP90) signaling in human lung fibroblasts and keratinocytes. Ong LC, Tan YF, Tan BS, Chung FF, Cheong SK, Leong CO. Toxicol Appl Pharmacol. 2017 Aug 15;329:347-357. doi: 10.1016/j.taap.2017.06.024. Epub 2017 Jul 1. PubMed
Chaperone proteins as single component reagents to assess antibody nonspecificity. Kelly RL, Geoghegan JC, Feldman J, Jain T, Kauke M, Le D, Zhao J, Wittrup KD. MAbs. 2017 Oct;9(7):1036-1040. doi: 10.1080/19420862.2017.1356529. Epub 2017 Jul 26. PubMed
Nickel ions bind to HSP90beta and enhance HIF-1alpha-mediated IL-8 expression. Asakawa S, Onodera R, Kasai K, Kishimoto Y, Sato T, Segawa R, Mizuno N, Ogasawara K, Moriya T, Hiratsuka M, Hirasawa N. Toxicology. 2018 Feb 15;395:45-53. doi: 10.1016/j.tox.2018.01.006. Epub 2018 Jan 31. PubMed
P62/SQSTM1 is a novel leucine-rich repeat kinase 2 (LRRK2) substrate that enhances neuronal toxicity. Kalogeropulou AF, Zhao J, Bolliger MF, Memou A, Narasimha S, Molitor TP, Wilson WH, Rideout HJ, Nichols RJ. Biochem J. 2018 Apr 9;475(7):1271-1293. doi: 10.1042/BCJ20170699. PubMed
Hop/STIP1 depletion alters nuclear structure via depletion of nuclear structural protein emerin. Kituyi SN, Edkins AL. Biochem Biophys Res Commun. 2018 Dec 9;507(1-4):503-509. doi: 10.1016/j.bbrc.2018.11.073. Epub 2018 Nov 16. PubMed
Non-enzymatic cleavage of Hsp90 by oxidative stress leads to actin aggregate formation: A novel gain-of-function mechanism. Castro JP, Fernando R, Reeg S, Meinl W, Almeida H, Grune T. Redox Biol. 2019 Feb;21:101108. doi: 10.1016/j.redox.2019.101108. Epub 2019 Jan 11. PubMed
Affinity Maturation Enhances Antibody Specificity but Compromises Conformational Stability. Shehata L, Maurer DP, Wec AZ, Lilov A, Champney E, Sun T, Archambault K, Burnina I, Lynaugh H, Zhi X, Xu Y, Walker LM. Cell Rep. 2019 Sep 24;28(13):3300-3308.e4. doi: 10.1016/j.celrep.2019.08.056. PubMed
Computational and cellular studies reveal structural destabilization and degradation of MLH1 variants in Lynch syndrome. Abildgaard AB, Stein A, Nielsen SV, Schultz-Knudsen K, Papaleo E, Shrikhande A, Hoffmann ER, Bernstein I, Gerdes AM, Takahashi M, Ishioka C, Lindorff-Larsen K, Hartmann-Petersen R. Elife. 2019 Nov 7;8. pii: 49138. doi: 10.7554/eLife.49138. PubMed
Inhibition of HSP90 S-nitrosylation Alleviates Cardiac Fibrosis via TGFbeta/SMAD3 Signaling Pathway. Zhang X, Zhang Y, Miao Q, Shi Z, Hu L, Liu S, Gao J, Zhao S, Chen H, Huang Z, Han Y, Ji Y, Xie L. Br J Pharmacol. 2021 Jul 15. doi: 10.1111/bph.15626. PubMed
HSP90 Modulates T2R Bitter Taste Receptor Nitric Oxide Production and Innate Immune Responses in Human Airway Epithelial Cells and Macrophages. Carey RM, Hariri BM, Adappa ND, Palmer JN, Lee RJ. Cells. 2022 Apr 27;11(9). pii: cells11091478. doi: 10.3390/cells11091478. PubMed
Machine learning classifiers predict key genomic and evolutionary traits across the kingdoms of life. Hallee L, Khomtchouk BB. Sci Rep. 2023 Feb 6;13(1):2088. doi: 10.1038/s41598-023-28965-7. PubMed
Valproic Acid Inhibits Progressive Hereditary Hearing Loss in a KCNQ4 Variant Model through HDAC1 Suppression. Nam YS, Choi YM, Lee S, Cho HH. Int J Mol Sci. 2023 Mar 16;24(6):5695. doi: 10.3390/ijms24065695. PubMed
Src-Dependent NM2A Tyrosine Phosphorylation Regulates Actomyosin Remodeling. Brito C, Pereira JM, Mesquita FS, Cabanes D, Sousa S. Cells. 2023 Jul 17;12(14):1871. doi: 10.3390/cells12141871. PubMed
Mechanisms by which barrier-to-autointegration factor regulates dynamics of nucleocytoplasmic leakage and membrane repair following nuclear envelope rupture. Halfmann CT, Scott KL, Sears RM, Roux KJ. bioRxiv [Preprint]. 2023 Dec 22:2023.12.21.572811. doi: 10.1101/2023.12.21.572811. PubMed

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