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pcDNA-dCas9-p300 Core (D1399Y) Citations (11)

Originally described in: Epigenome editing by a CRISPR-Cas9-based acetyltransferase activates genes from promoters and enhancers.
Hilton IB, D'Ippolito AM, Vockley CM, Thakore PI, Crawford GE, Reddy TE, Gersbach CA Nat Biotechnol. 2015 May;33(5):510-7. doi: 10.1038/nbt.3199. Epub 2015 Apr 6.
PubMed Journal

Articles Citing pcDNA-dCas9-p300 Core (D1399Y)

Epigenetic Regulation of Interleukin 6 by Histone Acetylation in Macrophages and Its Role in Paraquat-Induced Pulmonary Fibrosis. Hu L, Yu Y, Huang H, Fan H, Hu L, Yin C, Li K, Fulton DJ, Chen F. Front Immunol. 2017 Jan 30;7:696. doi: 10.3389/fimmu.2016.00696. eCollection 2016. PubMed
Ethanol Exposure Regulates Gabra1 Expression via Histone Deacetylation at the Promoter in Cultured Cortical Neurons. Bohnsack JP, Patel VK, Morrow AL. J Pharmacol Exp Ther. 2017 Oct;363(1):1-11. doi: 10.1124/jpet.117.242446. Epub 2017 Aug 10. PubMed
Temporal and Spatial Epigenome Editing Allows Precise Gene Regulation in Mammalian Cells. Kuscu C, Mammadov R, Czikora A, Unlu H, Tufan T, Fischer NL, Arslan S, Bekiranov S, Kanemaki M, Adli M. J Mol Biol. 2019 Jan 4;431(1):111-121. doi: 10.1016/j.jmb.2018.08.001. Epub 2018 Aug 9. PubMed
ATM and ATR Expression Potentiates HBV Replication and Contributes to Reactivation of HBV Infection upon DNA Damage. Kostyusheva A, Brezgin S, Bayurova E, Gordeychuk I, Isaguliants M, Goptar I, Urusov F, Nikiforova A, Volchkova E, Kostyushev D, Chulanov V. Viruses. 2019 Oct 31;11(11). pii: v11110997. doi: 10.3390/v11110997. PubMed
Clearing of Foreign Episomal DNA from Human Cells by CRISPRa-Mediated Activation of Cytidine Deaminases. Brezgin S, Kostyusheva A, Ponomareva N, Volia V, Goptar I, Nikiforova A, Shilovskiy I, Smirnov V, Kostyushev D, Chulanov V. Int J Mol Sci. 2020 Sep 18;21(18). pii: ijms21186865. doi: 10.3390/ijms21186865. PubMed
BAHCC1 binds H3K27me3 via a conserved BAH module to mediate gene silencing and oncogenesis. Fan H, Lu J, Guo Y, Li D, Zhang ZM, Tsai YH, Pi WC, Ahn JH, Gong W, Xiang Y, Allison DF, Geng H, He S, Diao Y, Chen WY, Strahl BD, Cai L, Song J, Wang GG. Nat Genet. 2020 Dec;52(12):1384-1396. doi: 10.1038/s41588-020-00729-3. Epub 2020 Nov 2. PubMed
Profiling of H3K27Ac Reveals the Influence of Asthma on the Epigenome of the Airway Epithelium. McErlean P, Kelly A, Dhariwal J, Kirtland M, Watson J, Ranz I, Smith J, Saxena A, Cousins DJ, Van Oosterhout A, Solari R, Edwards MR, Johnston SL, Lavender P. Front Genet. 2020 Dec 10;11:585746. doi: 10.3389/fgene.2020.585746. eCollection 2020. PubMed
Regulation of MYB by distal enhancer elements in human myeloid leukemia. Li M, Jiang P, Cheng K, Zhang Z, Lan S, Li X, Zhao L, Wang Y, Wang X, Chen J, Ji T, Han B, Zhang J. Cell Death Dis. 2021 Feb 26;12(2):223. doi: 10.1038/s41419-021-03515-z. PubMed
VEGFA's distal enhancer regulates its alternative splicing in CML. Dahan S, Sharma A, Cohen K, Baker M, Taqatqa N, Bentata M, Engal E, Siam A, Kay G, Drier Y, Elias S, Salton M. NAR Cancer. 2021 Jul 13;3(3):zcab029. doi: 10.1093/narcan/zcab029. eCollection 2021 Sep. PubMed
CRISPR-Mediated Synergistic Epigenetic and Transcriptional Control. Dominguez AA, Chavez MG, Urke A, Gao Y, Wang L, Qi LS. CRISPR J. 2022 Apr;5(2):264-275. doi: 10.1089/crispr.2021.0099. Epub 2022 Mar 10. PubMed
Isoforms of the TAL1 transcription factor have different roles in hematopoiesis and cell growth. Sharma A, Mistriel-Zerbib S, Najar RA, Engal E, Bentata M, Taqatqa N, Dahan S, Cohen K, Jaffe-Herman S, Geminder O, Baker M, Nevo Y, Plaschkes I, Kay G, Drier Y, Berger M, Salton M. PLoS Biol. 2023 Jun 28;21(6):e3002175. doi: 10.1371/journal.pbio.3002175. PubMed

Associated Plasmids

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