Proinsulin-NanoLuc in pLX304 Citations (10)
Originally described in: High-throughput luminescent reporter of insulin secretion for discovering regulators of pancreatic Beta-cell function.Burns SM, Vetere A, Walpita D, Dancik V, Khodier C, Perez J, Clemons PA, Wagner BK, Altshuler D Cell Metab. 2015 Jan 6;21(1):126-37. doi: 10.1016/j.cmet.2014.12.010. PubMed Journal
Articles Citing Proinsulin-NanoLuc in pLX304
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Gene Knock-Ins in Drosophila Using Homology-Independent Insertion of Universal Donor Plasmids.
Bosch JA, Colbeth R, Zirin J, Perrimon N.
Genetics. 2019 Nov 4. pii: genetics.119.302819. doi: 10.1534/genetics.119.302819.
PubMed
Associated Plasmids |
| Kisspeptin-Activated Autophagy Independently Suppresses Non-Glucose-Stimulated Insulin Secretion from Pancreatic beta-Cells. Huang C, Wang HY, Wang ME, Hsu MC, Wu YS, Jiang YF, Wu LS, Jong DS, Chiu CH. Sci Rep. 2019 Nov 25;9(1):17451. doi: 10.1038/s41598-019-53826-7. PubMed |
| Load and Display: Engineering Encapsulin as a Modular Nanoplatform for Protein-Cargo Encapsulation and Protein-Ligand Decoration Using Split Intein and SpyTag/SpyCatcher. Choi H, Eom S, Kim HU, Bae Y, Jung HS, Kang S. Biomacromolecules. 2021 Jul 12;22(7):3028-3039. doi: 10.1021/acs.biomac.1c00481. Epub 2021 Jun 18. PubMed |
| Novel Pathogenic De Novo INS p.T97P Variant Presenting With Severe Neonatal DKA. Lal RA, Moeller HP, Thomson EA, Horton TM, Lee S, Freeman R, Prahalad P, Poon ASY, Annes JP. Endocrinology. 2022 Feb 1;163(2):bqab246. doi: 10.1210/endocr/bqab246. PubMed |
| P2Y1 purinergic receptor identified as a diabetes target in a small-molecule screen to reverse circadian beta-cell failure. Marcheva B, Weidemann BJ, Taguchi A, Perelis M, Ramsey KM, Newman MV, Kobayashi Y, Omura C, Manning Fox JE, Lin H, Macdonald PE, Bass J. Elife. 2022 Feb 21;11. pii: 75132. doi: 10.7554/eLife.75132. PubMed |
| Novel luciferase-based glucagon-like peptide 1 reporter assay reveals naturally occurring secretagogues. Anghel SA, Badea RA, Chiritoiu G, Patriche DS, Alexandru PR, Pena F. Br J Pharmacol. 2022 Oct;179(19):4738-4753. doi: 10.1111/bph.15896. Epub 2022 Jul 21. PubMed |
| Genome-wide CRISPR screen identified a role for commander complex mediated ITGB1 recycling in basal insulin secretion. Yang L, Fye MA, Yang B, Tang Z, Zhang Y, Haigh S, Covington BA, Bracey K, Taraska JW, Kaverina I, Qu S, Chen W. Mol Metab. 2022 Sep;63:101541. doi: 10.1016/j.molmet.2022.101541. Epub 2022 Jul 11. PubMed |
| Rapid Quantification of First and Second Phase Insulin Secretion Dynamics using an In vitro Platform for Improving Insulin Therapy. Thoduvayil S, Weerakkody JS, Sundaram RVK, Topper M, Bera M, Coleman J, Li X, Mariappan M, Ramakrishnan S. Cell Calcium. 2023 Jul;113:102766. doi: 10.1016/j.ceca.2023.102766. Epub 2023 Jun 3. PubMed |
| Functional interrogation of twenty type 2 diabetes-associated genes using isogenic human embryonic stem cell-derived beta-like cells. Xue D, Narisu N, Taylor DL, Zhang M, Grenko C, Taylor HJ, Yan T, Tang X, Sinha N, Zhu J, Vandana JJ, Nok Chong AC, Lee A, Mansell EC, Swift AJ, Erdos MR, Zhong A, Bonnycastle LL, Zhou T, Chen S, Collins FS. Cell Metab. 2023 Nov 7;35(11):1897-1914.e11. doi: 10.1016/j.cmet.2023.09.013. Epub 2023 Oct 18. PubMed |
| Checkpoint kinase 2 controls insulin secretion and glucose homeostasis. Chong ACN, Vandana JJ, Jeng G, Li G, Meng Z, Duan X, Zhang T, Qiu Y, Duran-Struuck R, Coker K, Wang W, Li Y, Min Z, Zuo X, de Silva N, Chen Z, Naji A, Hao M, Liu C, Chen S. Nat Chem Biol. 2023 Nov 9. doi: 10.1038/s41589-023-01466-4. PubMed |
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