p2CT-His-MBP-Lbu_C2c2_WT Citations (12)

Originally described in: Two distinct RNase activities of CRISPR-C2c2 enable guide-RNA processing and RNA detection.
East-Seletsky A, O'Connell MR, Knight SC, Burstein D, Cate JH, Tjian R, Doudna JA Nature. 2016 Sep 26. doi: 10.1038/nature19802. PubMed Journal

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Articles Citing p2CT-His-MBP-Lbu_C2c2_WT

Articles
RNA Binding and HEPN-Nuclease Activation Are Decoupled in CRISPR-Cas13a. Tambe A, East-Seletsky A, Knott GJ, Doudna JA, O'Connell MR. Cell Rep. 2018 Jul 24;24(4):1025-1036. doi: 10.1016/j.celrep.2018.06.105. PubMed Associated Plasmids pDuBir-Lbu-dCas13a-avitag
A low-cost fluorescence reader for in vitro transcription and nucleic acid detection with Cas13a. Katzmeier F, Aufinger L, Dupin A, Quintero J, Lenz M, Bauer L, Klumpe S, Sherpa D, Durr B, Honemann M, Styazhkin I, Simmel FC, Heymann M. PLoS One. 2019 Dec 18;14(12):e0220091. doi: 10.1371/journal.pone.0220091. eCollection 2019. PubMed
Conditional control of RNA-guided nucleic acid cleavage and gene editing. Wang SR, Wu LY, Huang HY, Xiong W, Liu J, Wei L, Yin P, Tian T, Zhou X. Nat Commun. 2020 Jan 3;11(1):91. doi: 10.1038/s41467-019-13765-3. PubMed
A m(6) A Sensing Method by Its Impact on the Stability of RNA Double Helix. Yang S, Wu F, Peng S, Wang F, Chen Y, Yuan Y, Weng X, Zhou X. Chem Biodivers. 2020 May 5. doi: 10.1002/cbdv.202000050. PubMed
Amplification-free detection of SARS-CoV-2 with CRISPR-Cas13a and mobile phone microscopy. Fozouni P, Son S, Diaz de Leon Derby M, Knott GJ, Gray CN, D'Ambrosio MV, Zhao C, Switz NA, Kumar GR, Stephens SI, Boehm D, Tsou CL, Shu J, Bhuiya A, Armstrong M, Harris AR, Chen PY, Osterloh JM, Meyer-Franke A, Joehnk B, Walcott K, Sil A, Langelier C, Pollard KS, Crawford ED, Puschnik AS, Phelps M, Kistler A, DeRisi JL, Doudna JA, Fletcher DA, Ott M. Cell. 2021 Jan 21;184(2):323-333.e9. doi: 10.1016/j.cell.2020.12.001. Epub 2020 Dec 4. PubMed
Treatment of influenza and SARS-CoV-2 infections via mRNA-encoded Cas13a in rodents. Blanchard EL, Vanover D, Bawage SS, Tiwari PM, Rotolo L, Beyersdorf J, Peck HE, Bruno NC, Hincapie R, Michel F, Murray J, Sadhwani H, Vanderheyden B, Finn MG, Brinton MA, Lafontaine ER, Hogan RJ, Zurla C, Santangelo PJ. Nat Biotechnol. 2021 Jun;39(6):717-726. doi: 10.1038/s41587-021-00822-w. Epub 2021 Feb 3. PubMed
Accelerated RNA detection using tandem CRISPR nucleases. Liu TY, Knott GJ, Smock DCJ, Desmarais JJ, Son S, Bhuiya A, Jakhanwal S, Prywes N, Agrawal S, Diaz de Leon Derby M, Switz NA, Armstrong M, Harris AR, Charles EJ, Thornton BW, Fozouni P, Shu J, Stephens SI, Kumar GR, Zhao C, Mok A, Iavarone AT, Escajeda AM, McIntosh R, Kim S, Dugan EJ, Pollard KS, Tan MX, Ott M, Fletcher DA, Lareau LF, Hsu PD, Savage DF, Doudna JA. Nat Chem Biol. 2021 Sep;17(9):982-988. doi: 10.1038/s41589-021-00842-2. Epub 2021 Aug 5. PubMed Associated Plasmids pET_His6-SUMO-TEV-TtCsm6 pET28a_His-TEV-EiCsm6 pGJK_His-SUMO-LbuCas13a
Multiplexed biosensor for point-of-care COVID-19 monitoring: CRISPR-powered unamplified RNA diagnostics and protein-based therapeutic drug management. Johnston M, Ceren Ates H, Glatz RT, Mohsenin H, Schmachtenberg R, Goppert N, Huzly D, Urban GA, Weber W, Dincer C. Mater Today (Kidlington). 2022 Dec;61:129-138. doi: 10.1016/j.mattod.2022.11.001. Epub 2022 Nov 9. PubMed
Species-agnostic polymeric formulations for inhalable messenger RNA delivery to the lung. Rotolo L, Vanover D, Bruno NC, Peck HE, Zurla C, Murray J, Noel RK, O'Farrell L, Arainga M, Orr-Burks N, Joo JY, Chaves LCS, Jung Y, Beyersdorf J, Gumber S, Guerrero-Ferreira R, Cornejo S, Thoresen M, Olivier AK, Kuo KM, Gumbart JC, Woolums AR, Villinger F, Lafontaine ER, Hogan RJ, Finn MG, Santangelo PJ. Nat Mater. 2023 Mar;22(3):369-379. doi: 10.1038/s41563-022-01404-0. Epub 2022 Nov 28. PubMed
RNA-mediated Allosteric Activation in CRISPR-Cas13a. Sinha S, Molina Vargas AM, Arantes PR, Patel A, O'Connell MR, Palermo G. bioRxiv [Preprint]. 2023 Jul 27:2023.07.27.550797. doi: 10.1101/2023.07.27.550797. PubMed
Unveiling the RNA-mediated allosteric activation discloses functional hotspots in CRISPR-Cas13a. Sinha S, Molina Vargas AM, Arantes PR, Patel A, O'Connell MR, Palermo G. Nucleic Acids Res. 2024 Jan 25;52(2):906-920. doi: 10.1093/nar/gkad1127. PubMed
New design strategies for ultra-specific CRISPR-Cas13a-based RNA detection with single-nucleotide mismatch sensitivity. Molina Vargas AM, Sinha S, Osborn R, Arantes PR, Patel A, Dewhurst S, Hardy DJ, Cameron A, Palermo G, O'Connell MR. Nucleic Acids Res. 2024 Jan 25;52(2):921-939. doi: 10.1093/nar/gkad1132. PubMed

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