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pLX_311-KRAB-dCas9 Citations (7)

Plasmid Article: Complementary information derived from CRISPR Cas9 mediated gene deletion and suppression.
Rosenbluh J, Xu H, Harrington W, Gill S, Wang X, Vazquez F, Root DE, Tsherniak A, Hahn WC Nat Commun. 2017 May 23;8:15403. doi: 10.1038/ncomms15403.
PubMed Journal

Articles Citing pLX_311-KRAB-dCas9

Modulating Gene Expression in Epstein-Barr Virus (EBV)-Positive B Cell Lines with CRISPRa and CRISPRi. Wang LW, Trudeau SJ, Wang C, Gerdt C, Jiang S, Zhao B, Gewurz BE. Curr Protoc Mol Biol. 2018 Jan 16;121:31.13.1-31.13.18. doi: 10.1002/cpmb.50. PubMed
Optimized libraries for CRISPR-Cas9 genetic screens with multiple modalities. Sanson KR, Hanna RE, Hegde M, Donovan KF, Strand C, Sullender ME, Vaimberg EW, Goodale A, Root DE, Piccioni F, Doench JG. Nat Commun. 2018 Dec 21;9(1):5416. doi: 10.1038/s41467-018-07901-8. PubMed

Associated Plasmids

Identification of functional regulatory elements in the human genome using pooled CRISPR screens. Borys SM, Younger ST. BMC Genomics. 2020 Jan 31;21(1):107. doi: 10.1186/s12864-020-6497-0. PubMed
Identification of BLNK and BTK as mediators of rituximab-induced programmed cell death by CRISPR screens in GCB-subtype diffuse large B-cell lymphoma. Thomsen EA, Rovsing AB, Anderson MV, Due H, Huang J, Luo Y, Dybkaer K, Mikkelsen JG. Mol Oncol. 2020 Jun 25. doi: 10.1002/1878-0261.12753. PubMed
Selective Modulation of a Pan-Essential Protein as a Therapeutic Strategy in Cancer. Malone CF, Dharia NV, Kugener G, Forman AB, Rothberg MV, Abdusamad M, Gonzalez A, Kuljanin M, Robichaud AL, Conway AS, Dempster JM, Paolella BR, Dumont N, Hovestadt V, Mancias JD, Younger ST, Root DE, Golub TR, Vazquez F, Stegmaier K. Cancer Discov. 2021 Sep;11(9):2282-2299. doi: 10.1158/2159-8290.CD-20-1213. Epub 2021 Apr 21. PubMed
Synergistic action of WDR5 and HDM2 inhibitors in SMARCB1-deficient cancer cells. Florian AC, Woodley CM, Wang J, Grieb BC, Slota MJ, Guerrazzi K, Hsu CY, Matlock BK, Flaherty DK, Lorey SL, Fesik SW, Howard GC, Liu Q, Weissmiller AM, Tansey WP. NAR Cancer. 2022 Mar 3;4(1):zcac007. doi: 10.1093/narcan/zcac007. eCollection 2022 Mar. PubMed
Massively parallel identification of functionally consequential noncoding genetic variants in undiagnosed rare disease patients. McQuerry JA, Mclaird M, Hartin SN, Means JC, Johnston J, Pastinen T, Younger ST. Sci Rep. 2022 May 9;12(1):7576. doi: 10.1038/s41598-022-11589-8. PubMed

If you have published an article using this plasmid, please email us at [email protected] to have your article added to this page.