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Multidimensional control of therapeutic human cell function with synthetic gene circuits.

Li HS, Israni DV, Gagnon KA, Gan KA, Raymond MH, Sander JD, Roybal KT, Joung JK, Wong WW, Khalil AS
Science. 2022 Dec 16;378(6625):1227-1234. doi: 10.1126/science.ade0156. Epub 2022 Dec 15. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
195413pMN-009AAVS1 Integratable mCherry Reporter for synZiFTR ZF1
195414pMN-010AAVS1 Integratable mCherry Reporter for synZiFTR ZF2
195415pMN-011AAVS1 Integratable mCherry Reporter for synZiFTR ZF3
195416pMN-012AAVS1 Integratable mCherry Reporter for synZiFTR ZF4
195417pMN-013AAVS1 Integratable mCherry Reporter for synZiFTR ZF5
195418pMN-014AAVS1 Integratable mCherry Reporter for synZiFTR ZF6
195419pMN-015AAVS1 Integratable mCherry Reporter for synZiFTR ZF7
195420pMN-016AAVS1 Integratable mCherry Reporter for synZiFTR ZF8
195421pMN-017AAVS1 Integratable mCherry Reporter for synZiFTR ZF9
195422pMN-018AAVS1 Integratable mCherry Reporter for synZiFTR ZF10
195423pMN-019AAVS1 Integratable mCherry Reporter for synZiFTR ZF11
195424pMZ-176Transient, constitutive expression of synZiFTR: ZF1-p65
195425pMZ-177Transient, constitutive expression of synZiFTR: ZF2-p65
195426pMZ-178Transient, constitutive expression of synZiFTR: ZF3-p65
195427pMZ-179Transient, constitutive expression of synZiFTR: ZF4-p65
195428pMZ-180Transient, constitutive expression of synZiFTR: ZF5-p65
195429pMZ-181Transient, constitutive expression of synZiFTR: ZF6-p65
195430pMZ-182Transient, constitutive expression of synZiFTR: ZF7-p65
195431pMZ-183Transient, constitutive expression of synZiFTR: ZF8-p65
195432pMZ-184Transient, constitutive expression of synZiFTR: ZF9-p65
195433pMZ-185Transient, constitutive expression of synZiFTR: ZF10-p65
195434pMZ-186Transient, constitutive expression of synZiFTR: ZF11-p65
195435pO-066Lentiviral Integratable mCherry Reporter for synZiFTR ZF1
195436pO-081Lentiviral Integratable mCherry Reporter for synZiFTR ZF3
195437pO-070Lentiviral Integratable mCherry Reporter for synZiFTR ZF10
195438pMN-258Lentiviral Integratable mCherry Reporter for synZiFTR ZF1
195439pMN-259Lentiviral Integratable mCherry Reporter for synZiFTR ZF3
195440pMN-260Lentiviral Integratable mCherry Reporter for synZiFTR ZF10
195441pMN-322Lentiviral Integratable mCherry Reporter for synZiFTR ZF1
195442pMN-323Lentiviral Integratable mCherry Reporter for synZiFTR ZF3
195443pMN-324Lentiviral Integratable mCherry Reporter for synZiFTR ZF10
195444pMN-316Lentiviral Integratable mCherry Reporter for synZiFTR ZF1
195445pMN-317Lentiviral Integratable mCherry Reporter for synZiFTR ZF3
195446pMN-318Lentiviral Integratable mCherry Reporter for synZiFTR ZF10
195447pMN-319Lentiviral Integratable mCherry Reporter for synZiFTR ZF1
195448pMN-320Lentiviral Integratable mCherry Reporter for synZiFTR ZF3
195449pMN-321Lentiviral Integratable mCherry Reporter for synZiFTR ZF10
195450pMN-325Lentiviral Integratable mCherry Reporter for synZiFTR ZF1
195451pMN-326Lentiviral Integratable mCherry Reporter for synZiFTR ZF3
195452pMN-327Lentiviral Integratable mCherry Reporter for synZiFTR ZF10
195453pMN-294Lentiviral Integratable mCherry Reporter for synZiFTR ZF1
195454pMN-296Lentiviral Integratable mCherry Reporter for synZiFTR ZF3
195455pMN-303Lentiviral Integratable mCherry Reporter for synZiFTR ZF10
195456pMZ-345Lentiviral Integratable, constitutive expression of synZiFTR: ZF1-p65
195457pMZ-346Lentiviral Integratable, constitutive expression of synZiFTR: ZF3-p65
195458pMZ-347Lentiviral Integratable, constitutive expression of synZiFTR: ZF10-p65
195459pMZ-314Lentiviral Integratable, ABA-inducible expression of synZiFTR: ZF1-p65
195460pHS_235Lentiviral Integratable, 4OHT/TMX-inducible expression of synZiFTR: ZF3-p65
195461pHS-139Lentiviral Integratable, GZV-inducible expression of synZiFTR: ZF10-p65
195462pMZ-431Lentiviral Integratable, 4OHT/TMX- and GZV-controllable expression of synZiFTR: ZF3-p65
195463pMZ-432Lentiviral Integratable, 4OHT/TMX- and GZV-controllable expression of synZiFTR: ZF3-p65
195464pMZ-440Lentiviral Integratable, 4OHT/TMX- and GZV-controllable expression of synZiFTR: KRAB-ZF3
195465pMZ-441Lentiviral Integratable, 4OHT/TMX- and GZV-controllable expression of synZiFTR: HP1a-ZF3
195466pMN-332Lentiviral Integratable Inducible synZiFTR ZF1 + Reporter
195467pMN-333Lentiviral Integratable Inducible synZiFTR ZF3 + Reporter
195468pMN-334Lentiviral Integratable Inducible synZiFTR ZF10 + Reporter
195469pBW-507Lentiviral Integratable Constitutive CD19CAR
195470pHS-435Lentiviral Integratable Constitutive super IL-2 cytokine
195471pHS-439Lentiviral Integratable Inducible superIL-2 cytokine using synZiFTR ZF3
195472pMN-285Lentiviral Integratable Inducible CD19CAR using synZiFTR ZF10
195473pHS-393Lentiviral Integratable Inducible super-IL2 cytokine + synZiFTR10

Antibodies from Article