Manipulation of very few receptor discriminator residues greatly enhances receptor specificity of non-visual arrestins.
Gimenez LE, Vishnivetskiy SA, Baameur F, Gurevich VV
J Biol Chem. 2012 Aug 24;287(35):29495-505. doi: 10.1074/jbc.M112.366674. Epub 2012 Jul 11.
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Plasmids from Article
ID | Plasmid | Purpose |
---|---|---|
234807 | p3HM2Luc | Mammalian expression of human muscarinic M2 receptor fused to RLuc8 |
234808 | p3HB2ALuc | Mammalian expression of human B2-adrenergic receptor fused to RLuc8 |
236275 | p3HAT1Luc1 | Mammalian expression of human angiotensin II type 1 receptor; N-terminal HA tag, C-terminal Rluc8 |
236276 | p3HD1RLuc2 | Mammalian expression of human dopamine D1 receptor; N-terminal HA tag, C-terminal Rluc8 |
236277 | p3HM1Luc4 | Mammalian expression of human muscarinic M1 receptor; N-terminal HA tag, C-terminal Rluc8 |