Phosphorylation of ULK1 (hATG1) by AMP-activated protein kinase connects energy sensing to mitophagy.
Egan DF, Shackelford DB, Mihaylova MM, Gelino S, Kohnz RA, Mair W, Vasquez DS, Joshi A, Gwinn DM, Taylor R, Asara JM, Fitzpatrick J, Dillin A, Viollet B, Kundu M, Hansen M, Shaw RJ
Science. 2011 Jan 28;331(6016):456-61. doi: 10.1126/science.1196371. Epub 2010 Dec 23.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 27623 | pDONR221 - myc ULK1 wt | |
| 27624 | pDONR221 - myc ULK1 k46I | |
| 27625 | pDONR221 - myc ULK1 4SA | |
| 27626 | pQCXIN- myc ULK1 wt | |
| 27627 | pQCXIN- myc ULK1 K46I | |
| 27628 | pQCXIN- myc ULK1 4SA | |
| 27629 | pcdna6.2- myc ULK1 wt | |
| 27630 | pcdna6.2- myc ULK1 k46I | |
| 27631 | pcdna6.2- myc ULK1 4SA | |
| 27632 | pEBG‐AMPK α1(1‐312) | |
| 27633 | pLKO human ULK1 shRNA 8 | |
| 27634 | pLKO human ULK2 shRNA 91 | |
| 27635 | pLKO mouse ULK2 shRNA 93 | |
| 27636 | pcdna3 flag - ULK1 wt | |
| 27637 | pcdna3 flag - ULK2 wt |