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Scalable signaling mediated by T cell antigen receptor-CD3 ITAMs ensures effective negative selection and prevents autoimmunity.
Holst J, Wang H, Eder KD, Workman CJ, Boyd KL, Baquet Z, Singh H, Forbes K, Chruscinski A, Smeyne R, van Oers NS, Utz PJ, Vignali DA
Nat Immunol. 2008 Jun;9(6):658-66. doi: 10.1038/ni.1611. Epub 2008 May 11.
PubMed Article

Plasmids from Article

ID Plasmid Purpose  
52092Murine CD3 WTdelta-F2A-gamma-T2A-epsilon-P2A-zeta pMIG IIRetroviral expression of all four WT CD3 subunits, co-expressed with EGFP
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52093Murine CD3 WTdelta-F2A-gamma-T2A-epsilon-P2A-zeta pMIA IIRetroviral expression of all four WT CD3 subunits, co-expressed with mAmetrine
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Antibodies from Article