We narrowed to 276 results for: SYN1

1. AAV-Synapsin-Ypet-optoJNKi-WPRE

   Plasmid

   #159967

   Purpose

   optogenetic JNK inhibitor with increased RET from LOV2 to reduce actuation sensitivity, detectable without activation

   Depositor

   Michael Courtney

   Article

   Li et al Nat Commun. 2020 Oct 9;11(1):5107. doi:

   Insert

   Ypet-optoJNKi
   

   Use

   AAV

   Tags

   Expression

   Mammalian

   Mutation

   synthetic

   Promoter

   hSyn1

   Available since

   Oct. 22, 2020

   Availability

   Academic Institutions and Nonprofits only

   

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2. pAAV-hSyn-ChRger2-TS-EYFP

   Plasmid

   #127237

   Purpose

   High photocurrent, low-light sensitive channelrhodopsin (ChRger2) for optogenetic activation with systemic delivery or for low-light activation. Driven by human Synapsin I promoter.

   Depositor

   Viviana Gradinaru

   Article

   Bedbrook et al Nat Methods. 2019 Oct 14. pii: 10.1038/s

   Insert

   ChRger2-TS-EYFP
   

   Use

   AAV

   Tags

   EYFP and SpyTag

   Expression

   Mammalian

   Mutation

   Promoter

   hSyn1

   Available since

   Sept. 27, 2019

   Availability

   Academic Institutions and Nonprofits only

   

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3. pAAV-hSyn-ChRger3-TS-EYFP

   Plasmid

   #127240

   Purpose

   High photocurrent, low-light sensitive channelrhodopsin (ChRger3) for optogenetic activation with systemic delivery or for low-light activation. Driven by human Synapsin I promoter.

   Depositor

   Viviana Gradinaru

   Article

   Bedbrook et al Nat Methods. 2019 Oct 14. pii: 10.1038/s

   Insert

   ChRger3-TS-EYFP
   

   Use

   AAV

   Tags

   EYFP and SpyTag

   Expression

   Mammalian

   Mutation

   Promoter

   hSyn1

   Available since

   Sept. 27, 2019

   Availability

   Academic Institutions and Nonprofits only

   

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4. pAAV-pCALM1-EYFP-WPRE-bGHpA

   Plasmid

   #213971

   Purpose

   AAV expression of EYFP from pCALM1 promoter

   Depositor

   Zhonghua Lu

   Article

   Wang et al Cell Rep. 2023 Nov 28;42(11):113348. doi

   Insert

   pCALM1
   

   Use

   AAV

   Tags

   Expression

   Mutation

   Promoter

   Available since

   April 29, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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5. pAAV-hSyn-ChRger1-TS-EYFP

   Plasmid

   #127243

   Purpose

   High photocurrent, low-light sensitive channelrhodopsin (ChRger1) for optogenetic activation with systemic delivery or for low-light activation. Driven by human Synapsin I promoter.

   Depositor

   Viviana Gradinaru

   Article

   Bedbrook et al Nat Methods. 2019 Oct 14. pii: 10.1038/s

   Insert

   ChRger1-TS-EYFP
   

   Use

   AAV

   Tags

   EYFP and SpyTag

   Expression

   Mammalian

   Mutation

   Promoter

   hSyn1

   Available since

   Sept. 27, 2019

   Availability

   Academic Institutions and Nonprofits only

   

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6. pAAV-pCALM1-SpCas9-miniU6-sgRNAShank3

   Plasmid

   #213973

   Purpose

   AAV vector to express SpCas9 driven by pCALM1 promoter for targeting Shank3 locus

   Depositor

   Zhonghua Lu

   Article

   Wang et al Cell Rep. 2023 Nov 28;42(11):113348. doi

   Insert

   Shank3 sgRNA
   

   Use

   AAV and CRISPR

   Tags

   Expression

   Mutation

   Promoter

   Available since

   May 15, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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7. pAAV-G88P7-rM3Ds-2A-EYFP

   Plasmid

   #213970

   Purpose

   AAV vector with G88P7 promoter in order to induce robust expression of rM3Ds in MSNs

   Depositor

   Zhonghua Lu

   Article

   Chen et al Cell. 2023 Nov 22;186(24):5394-5410.e18.

   Insert

   rM3Ds
   

   Use

   AAV

   Tags

   Expression

   Mutation

   Promoter

   G88P7

   Available since

   April 29, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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8. pAAV-VTKS1

   Plasmid

   #170852

   Purpose

   AAV backbone for transgene expression in neurons under the control of the hSyn1 promoter.

   Depositor

   Jordane Dimidschstein

   Article

   Pouchelon et al Cell Rep Methods. 2022 May 26;2(6):10022

   Type

   Empty backbone

   Use

   AAV

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   Available since

   May 26, 2022

   Availability

   Academic Institutions and Nonprofits only

   

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9. FSW-ALDH2-T2A-EGFP

   Plasmid

   #197036

   Purpose

   Express ALDH2 from hSyn1 promoter, co-expressed with EGFP

   Depositor

   Ronald Hart

   Article

   Sun et al Aging Cell. 2023 Feb;22(2):e13772. doi:

   Insert

   ALDH2 (ALDH2 Human)
   

   Use

   Lentiviral

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   Available since

   March 2, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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10. pAAV Syn 2xLyn-ERex-Venus-bPAC(F198Y)

    Plasmid

    #165491

    Purpose

    Neuronal expression of PACmn, a photoactivatable adenylyl cyclase derived from bPAC, membrane-anchored, no/reduced dark activity .

    Depositor

    Thomas Oertner

    Article

    Yang et al BMC Biol. 2021 Oct 18;19(1):227. doi: 10

    Insert

    2xLyn-ERex-Venus-bPAC(F198Y)
    

    Use

    AAV

    Tags

    Venus

    Expression

    Mammalian

    Mutation

    Promoter

    hSyn1

    Available since

    Oct. 21, 2021

    Availability

    Academic Institutions and Nonprofits only

    

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11. pAAV-hSyn-ASAP2s

    Plasmid

    #101276

    Purpose

    Genetically encoded voltage indicator (GEVI) ASAP2s in AAV vector for neuron-specific expression using the promoter hSyn1

    Depositor

    Francois St-Pierre

    Article

    Chamberland et al eLife. 2017 Jul 27;6. pii: e25690. doi:

    Insert

    ASAP2s
    

    Use

    AAV

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    hSyn (human synapsin)

    Available since

    Oct. 23, 2017

    Availability

    Academic Institutions and Nonprofits only

    

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12. pAAV-VTKS3

    Plasmid

    #170854

    Purpose

    AAV backbone for Flp-dependent transgene expression of any transgene in neurons under the control of the hSyn1 promoter.

    Depositor

    Jordane Dimidschstein

    Article

    Pouchelon et al Cell Rep Methods. 2022 May 26;2(6):10022

    Type

    Empty backbone

    Use

    AAV

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    May 26, 2022

    Availability

    Academic Institutions and Nonprofits only

    

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13. pAAV-G88P3-HA-hM3Dq

    Plasmid

    #213972

    Purpose

    AAV vector with G88P3 promoter that can drive robust gene expression in MSNs

    Depositor

    Zhonghua Lu

    Article

    Chen et al Cell. 2023 Nov 22;186(24):5394-5410.e18.

    Insert

    hM3D (Gq)
    

    Use

    AAV

    Tags

    Expression

    Mutation

    Promoter

    G88P3

    Available since

    May 15, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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14. pAAV-VTKS2

    Plasmid

    #170853

    Purpose

    AAV backbone for Cre-dependent transgene expression of any transgene in neurons under the control of the hSyn1 promoter.

    Depositor

    Jordane Dimidschstein

    Article

    Pouchelon et al Cell Rep Methods. 2022 May 26;2(6):10022

    Type

    Empty backbone

    Use

    AAV

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    May 26, 2022

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

15. pU6-crRNA(Non-targeting)

    Plasmid

    #109324

    Purpose

    AAV vector expressing non-targeting AsCpf1 crRNA

    Depositor

    Feng Zhang

    Article

    Tekin et al Nat Biomed Eng. 2018 Jul;2(7):540-554. d

    Insert

    mCherry-KASH
    

    Use

    AAV

    Tags

    Expression

    Mutation

    Promoter

    hSyn1

    Available since

    April 30, 2018

    Availability

    Academic Institutions and Nonprofits only

    

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16. pLenSyn2-EGFP-­OMP25C

    Plasmid

    #71427

    Purpose

    Lentiviral expression of EGFP-OMP25C. For visualization of neuronal mitochondria.

    Depositor

    Henri Huttunen

    Article

    Kysenius et al PLoS One. 2014 Sep 5;9(9):e107129. doi:

    Insert

    OMP25 (172-­‐206) (Synj2bp Rat)
    

    Use

    Lentiviral

    Tags

    EGFP

    Expression

    Mammalian

    Mutation

    aa 172-206 only

    Promoter

    synapsin

    Available since

    Dec. 10, 2015

    Availability

    Academic Institutions and Nonprofits only

17. pAAV-VTKS1-hChR2-tBFP

    Plasmid

    #178706

    Purpose

    AAV vector for transgene expression of hChR2-tBFP in neurons under the control of the hSyn1 promoter (Kugler et al 2003)

    Depositor

    Jordane Dimidschstein

    Article

    Pouchelon et al Cell Rep Methods. 2022 May 26;2(6):10022

    Insert

    hChR2-tBFP
    

    Use

    AAV

    Tags

    Expression

    Mutation

    Promoter

    Available since

    May 26, 2022

    Availability

    Academic Institutions and Nonprofits only

    

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18. pAAV-pCALM1-sFLEx-HA-SpCas9-miniU6-sgRNAShank3

    Plasmid

    #213969

    Purpose

    AAV vector for encoding SpCas9 driven by pCALM1 promoter targeting Shank3 locus in the presence of Cre recombinase

    Depositor

    Zhonghua Lu

    Article

    Wang et al Cell Rep. 2023 Nov 28;42(11):113348. doi

    Insert

    Shank3 sgRNA
    

    Use

    AAV and CRISPR

    Tags

    Expression

    Mutation

    Promoter

    Available since

    May 15, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

19. pAAV-VTKS4

    Plasmid

    #170855

    Purpose

    AAV backbone for Cre- and Flp-dependent transgene expression (CRE-ON / FLP-ON) of any transgene in neurons under the control of the hSyn1 promoter.

    Depositor

    Jordane Dimidschstein

    Article

    Pouchelon et al Cell Rep Methods. 2022 May 26;2(6):10022

    Type

    Empty backbone

    Use

    AAV

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    May 26, 2022

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

20. pAAV_hsyn_NES-his-CaMPARI2-F391W-L398V

    Plasmid

    #119723

    Purpose

    AAV vector expressing CaMPARI2_F391W-L398V (Kd = 174nM), a photoconvertible fluorescent protein-based calcium integrator, in neurons

    Depositor

    Thomas Oertner

    Article

    Moeyaert et al Nat Commun. 2018 Oct 25;9(1):4440. doi:

    Inserts

    CaMPARI2
    CaMPARI2
    

    Use

    AAV

    Tags

    NES-his

    Expression

    Mammalian

    Mutation

    F391W, L398V

    Promoter

    hSyn1

    Available since

    Jan. 31, 2019

    Availability

    Academic Institutions and Nonprofits only

    

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