We narrowed to 8,159 results for: aav

1. pC130: pAAV.CMV-CasRx-VEGFA sgRNA

   Plasmid

   #203443

   Purpose

   Plasmid expressing active RfxCas13d with VEGFA mRNA targeting gRNA

   Depositor

   Guei-Sheung Liu

   Article

   Kumar et al Proc Natl Acad Sci U S A. 2024 Nov 5;121

   Inserts

   U6-VEGFA sgRNA
   RfxCas13d
   

   Use

   AAV

   Tags

   HA and NLS

   Expression

   Mammalian

   Promoter

   CMV and U6

   Available Since

   Dec. 12, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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2. pM149: pAAV.CMV-Cas13e-VEGFA sgRNA

   Plasmid

   #203447

   Purpose

   Plasmid expressing active Cas13e with VEGFA mRNA targeting gRNA

   Depositor

   Guei-Sheung Liu

   Article

   Kumar et al Proc Natl Acad Sci U S A. 2024 Nov 5;121

   Inserts

   U6-VEGFA sgRNA
   Cas13e
   

   Use

   AAV

   Tags

   HA and NLS

   Expression

   Mammalian

   Promoter

   CMV and U6

   Available Since

   Dec. 12, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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3. pM155: pAAV.CMV-Cas13e (GenScript CO)-NT sgRNA

   Plasmid

   #203451

   Purpose

   Plasmid expressing active and codon optimised Cas13e with non-targeting gRNA

   Depositor

   Guei-Sheung Liu

   Article

   Kumar et al Proc Natl Acad Sci U S A. 2024 Nov 5;121

   Inserts

   U6-non targeting (NT) sgRNA
   Cas13e
   

   Use

   AAV

   Tags

   HA and NLS

   Expression

   Mammalian

   Mutation

   Codon optimised using GenScript tool

   Promoter

   CMV and U6

   Available Since

   Dec. 12, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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4. pC368: pAAV.CMV-Cas13e-VEGFA sgRNA2

   Plasmid

   #227800

   Purpose

   Plasmid expressing active Cas13e with VEGFA mRNA targeting gRNA2

   Depositor

   Guei-Sheung Liu

   Article

   Kumar et al Proc Natl Acad Sci U S A. 2024 Nov 5;121

   Inserts

   U6-VEGFA sgRNA 2 (Vegfa Synthetic)
   Cas13e
   

   Use

   AAV

   Tags

   HA and NLS

   Expression

   Mammalian

   Available Since

   Dec. 12, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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5. pC369: pAAV.CMV-Cas13e-VEGFA sgRNA3

   Plasmid

   #227801

   Purpose

   Plasmid expressing active Cas13e with VEGFA mRNA targeting gRNA3

   Depositor

   Guei-Sheung Liu

   Article

   Kumar et al Proc Natl Acad Sci U S A. 2024 Nov 5;121

   Inserts

   U6-VEGFA sgRNA 3 (Vegfa Synthetic)
   Cas13e
   

   Use

   AAV

   Tags

   HA and NLS

   Expression

   Mammalian

   Available Since

   Dec. 12, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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6. pAAV-Syn-DiO-eGFP-2A-mCherry_YDA

   Plasmid

   #194881

   Purpose

   Ratiometric YDA sensor for in vivo cre-dependent neuron-specific cholesterol visualization

   Depositor

   Peter Scheiffele

   Article

   Czernecki et al bioRxiv 2022.11.16.516849

   Insert

   GFP-T2A-mCherry-YDA
   

   Use

   AAV and Cre/Lox

   Expression

   Mammalian

   Promoter

   human Synapsin

   Available Since

   Dec. 11, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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7. AAVS1-TRE-GFP-TurboID-HA-rtTA

   Plasmid

   #226996

   Purpose

   Integrative plasmid to express GFP-TurboID in mammalian cells

   Depositor

   Bruno Dallagiovanna

   Article

   Gomes-Junior et al PLoS One. 2025 May 30;20(5):e0324779. do

   Insert

   Green fluorescent protein (gfp Synthetic)
   

   Tags

   TurboID-HA

   Expression

   Mammalian

   Available Since

   Nov. 14, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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8. pAAV-CMV-dSa VP64 Afp

   Plasmid

   #99697

   Purpose

   Expresses dSa Cas9 fused to gold standard VP64 activator domain and Sa sgRNA for Afp promoter, vector allows for activation of mouse Afp, can be packaged and delivered as AAV

   Depositor

   George Church

   Insert

   dCas9 and gRNA targeting Afp (Afp Synthetic)
   

   Use

   AAV and CRISPR

   Tags

   VP64

   Mutation

   dead Cas9

   Available Since

   Nov. 4, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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9. AAV-U6-sgLacZ-U6-sgGFP-hSyn1-mCherry

   Plasmid

   #208834

   Purpose

   Control plasmid expresses mCherry under the hSyn1 promoter with sgRNAs against LacZ and GFP

   Depositor

   Ben Emery

   Article

   Duncan et al Nat Commun. 2024 Oct 23;15(1):9148. doi:

   Insert

   mCherry
   

   Use

   AAV and CRISPR

   Expression

   Bacterial and Mammalian

   Promoter

   hSyn1

   Available Since

   Oct. 23, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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10. AAV-U6-sgMap3K12(1)-U6-sgMap3K12(2)-hSyn1-mCherry

    Plasmid

    #208835

    Purpose

    Knockout of Map3K12 (DLK) using tandem sgRNAs, expresses mCherry under the hSyn1 promoter

    Depositor

    Ben Emery

    Article

    Duncan et al Nat Commun. 2024 Oct 23;15(1):9148. doi:

    Insert

    mCherry
    

    Use

    AAV and CRISPR

    Expression

    Bacterial and Mammalian

    Promoter

    hSyn1

    Available Since

    Oct. 23, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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11. AAV-U6-sgMap3K13(1)-U6-sgMap3K13(2)-hSyn1-mCherry

    Plasmid

    #208836

    Purpose

    Knockout of Map3K13 (LZK) using tandem sgRNAs, expresses mCherry under the hSyn1 promoter

    Depositor

    Ben Emery

    Article

    Duncan et al Nat Commun. 2024 Oct 23;15(1):9148. doi:

    Insert

    mCherry
    

    Use

    AAV and CRISPR

    Expression

    Bacterial and Mammalian

    Promoter

    hSyn1

    Available Since

    Oct. 23, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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12. AAV-U6-sgMap3K13(1)-U6-sgMap3K12(1)-hSyn1-mCherry

    Plasmid

    #208837

    Purpose

    Knockout of Map3K12 (DLK) and Map3K13 (LZK) using tandem sgRNAs, expresses mCherry under the hSyn1 promoter

    Depositor

    Ben Emery

    Article

    Duncan et al Nat Commun. 2024 Oct 23;15(1):9148. doi:

    Insert

    mCherry
    

    Use

    AAV and CRISPR

    Expression

    Bacterial and Mammalian

    Promoter

    hSyn1

    Available Since

    Oct. 23, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

13. DRH031_ AAV-SIO-nEF-WT-THR

    Plasmid

    #225090

    Purpose

    Cre-dependent expression of wild-type thyroid receptor beta (THRB, human) in neurons driven by nEF promoter.

    Depositor

    Bernardo Sabatini

    Article

    Hochbaum et al Cell. 2024 Oct 3;187(20):5679-5697.e23.

    Insert

    DN-THRB (THRB Human)
    

    Use

    AAV

    Available Since

    Oct. 21, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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14. DRH032_ AAV-SIO-nEF-DN-THR

    Plasmid

    #225091

    Purpose

    Cre-dependent expression of dominant-negative thyroid receptor beta (THRB, human) in neurons driven by nEF promoter.

    Depositor

    Bernardo Sabatini

    Article

    Hochbaum et al Cell. 2024 Oct 3;187(20):5679-5697.e23.

    Insert

    WT-THRB (THRB Human)
    

    Use

    AAV

    Available Since

    Oct. 21, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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15. AAVS1_dCas9-XTEN-KRAB-p2A-mCherry

    Plasmid

    #222107

    Purpose

    Donor vector for CRISPRi integration at AAVS1 with an mCherry fluorophore

    Depositor

    Jonathan Weissman

    Article

    She et al Cell. 2023 Jul 6;186(14):2977-2994.e23.

    Insert

    CRISPRi-kox1(KRAB) (cas9 Human, S. pyogenes)
    

    Use

    AAV and CRISPR

    Tags

    HA and P2A-mCherry

    Expression

    Mammalian

    Mutation

    D10A, H840A

    Available Since

    Oct. 10, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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16. AAVS1_dCas9-XTEN-KRAB-p2A-GFP

    Plasmid

    #222108

    Purpose

    Donor vector for CRISPRi integration at AAVS1 with a GFP fluorophore

    Depositor

    Jonathan Weissman

    Article

    She et al Cell. 2023 Jul 6;186(14):2977-2994.e23.

    Insert

    CRISPRi-kox1(KRAB) (cas9 Human, S. pyogenes)
    

    Use

    AAV and CRISPR

    Tags

    HA and P2A-GFP

    Expression

    Mammalian

    Mutation

    D10A, H840A

    Available Since

    Oct. 4, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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17. pAAV-U6-sgPet-1-hSyn-mCherry-KASH

    Plasmid

    #223227

    Purpose

    guideRNA targeting the mouse Pet-1 (Fev)

    Depositor

    Kyungjin Kim

    Article

    Park et al Commun Biol. 2024 Aug 15;7(1):998. doi:

    Insert

    Fev (Fev Mouse)
    

    Use

    AAV, CRISPR, and Mouse Targeting

    Tags

    mCherry

    Expression

    Mammalian

    Promoter

    U6

    Available Since

    Sept. 11, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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18. pBK1302-AAV-EFSNC-dCjCas9-KRAB

    Plasmid

    #223147

    Purpose

    Expression of KRAB with dCjCas9 and empty gRNA scaffold

    Depositor

    Boris Kantor

    Article

    Kantor et al bioRxiv [Preprint]. 2024 May 19:2023.04.

    Insert

    KRAB
    

    Use

    AAV and CRISPR

    Tags

    3xFLAG

    Expression

    Mammalian

    Promoter

    EF1a

    Available Since

    Aug. 23, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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19. pAAV-Tnnt2-Cre-U6-Lmna-sgRNA

    Plasmid

    #206178

    Purpose

    Expresses Cre recombinase specifically in cardiomyocytes and uses U6 promoter to express sgRNAs targeting murine Lmna exon 10

    Depositor

    Yuxuan Guo

    Article

    Sun et al JACC Basic Transl Sci. 2024 Aug 21;9(11)

    Insert

    Cre
    

    Use

    AAV

    Promoter

    cTnT

    Available Since

    Aug. 23, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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20. pAAV-Loxp-CMV-Loxp-GFP-LA

    Plasmid

    #206199

    Purpose

    Expresses GFP-lamin-A only in non-myocyte when delivered into mice carrying a cardiomyocyte-specific Myh6-Cre transgene

    Depositor

    Yuxuan Guo

    Article

    Sun et al JACC Basic Transl Sci. 2024 Aug 21;9(11)

    Insert

    Lmna (LMNA Human)
    

    Use

    AAV

    Tags

    GFP

    Promoter

    CMV

    Available Since

    Aug. 23, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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