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TDP-43_CTD_M339A

Plasmid

#248886

Purpose

Edit Expresses 6xHis-tagged C-terminal domain of TDP-43 with M339A.

Depositor

Nicolas Fawzi

Article

Rizuan et al Nat Commun. 2025 Nov 26;16(1):10528. doi

Insert

TDP-43_CTD_M339A (TARDBP Human)

Tags

6xHis-tags

Expression

Bacterial

Mutation

changed M339A

Available Since

Dec. 2, 2025

Availability

Academic Institutions and Nonprofits only

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TDP-43_CTD_L340A

Plasmid

#248887

Purpose

Edit Expresses 6xHis-tagged C-terminal domain of TDP-43 with L340A.

Depositor

Nicolas Fawzi

Article

Rizuan et al Nat Commun. 2025 Nov 26;16(1):10528. doi

Insert

TDP-43_CTD_L340A (TARDBP Human)

Tags

6xHis-tags

Expression

Bacterial

Mutation

changed L340A

Available Since

Dec. 2, 2025

Availability

Academic Institutions and Nonprofits only

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TDP-43_CTD_S342A

Plasmid

#248888

Purpose

Expresses 6xHis-tagged C-terminal domain of TDP-43 with S342A.

Depositor

Nicolas Fawzi

Article

Rizuan et al Nat Commun. 2025 Nov 26;16(1):10528. doi

Insert

TDP-43_CTD_S342A (TARDBP Human)

Tags

6xHis-tags

Expression

Bacterial

Mutation

changed S342A

Available Since

Dec. 2, 2025

Availability

Academic Institutions and Nonprofits only

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TDP-43_CTD_M336A

Plasmid

#248884

Purpose

Expresses 6xHis-tagged C-terminal domain of TDP-43 with M336A.

Depositor

Nicolas Fawzi

Article

Rizuan et al Nat Commun. 2025 Nov 26;16(1):10528. doi

Insert

TDP-43_CTD_M336A (TARDBP Human)

Tags

6xHis-tags

Expression

Bacterial

Mutation

changed M336A

Available Since

Dec. 2, 2025

Availability

Academic Institutions and Nonprofits only

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TDP-43_CTD_S333A

Plasmid

#248882

Purpose

Expresses 6xHis-tagged C-terminal domain of TDP-43 with S333A.

Depositor

Nicolas Fawzi

Article

Rizuan et al Nat Commun. 2025 Nov 26;16(1):10528. doi

Insert

TDP-43_CTD_S333A (TARDBP Human)

Tags

6xHis-tags

Expression

Bacterial

Mutation

changed S333A

Available Since

Dec. 2, 2025

Availability

Academic Institutions and Nonprofits only

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TDP-43_CTD_W334A

Plasmid

#248883

Purpose

Expresses 6xHis-tagged C-terminal domain of TDP-43 with W334A.

Depositor

Nicolas Fawzi

Article

Rizuan et al Nat Commun. 2025 Nov 26;16(1):10528. doi

Insert

TDP-43_CTD_W334A (TARDBP Human)

Tags

6xHis-tags

Expression

Bacterial

Mutation

changed W334A

Available Since

Dec. 2, 2025

Availability

Academic Institutions and Nonprofits only

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pLentiCRISPR V2 HMBS_sg2

Plasmid

#244860

Purpose

Knockout of human HMBS

Depositor

Alexis Jourdain

Article

Harhai et al Cell Rep. 2025 Jul 25;44(8):116069. doi:

Insert

HMBS sgRNA (HMBS Human)

Use

CRISPR and Lentiviral

Promoter

U6

Available Since

Oct. 15, 2025

Availability

Academic Institutions and Nonprofits only

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pLentiCRISPR V2 HMBS_sg1

Plasmid

#244859

Purpose

Knockout of human HMBS

Depositor

Alexis Jourdain

Article

Harhai et al Cell Rep. 2025 Jul 25;44(8):116069. doi:

Insert

HMBS sgRNA (HMBS Human)

Use

CRISPR and Lentiviral

Promoter

U6

Available Since

Oct. 15, 2025

Availability

Academic Institutions and Nonprofits only

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LentiCRISPR-B_sgRNA_RPP29 (pAVA3545)

Plasmid

#239314

Purpose

Lentiviral vector expressing Cas9-P2A-Blasticidin and an sgRNA targeting RPP29

Depositor

Andrei Alexandrov

Article

Che et al Nat Commun. 2025 May 22;16(1):4741. doi:

Insert

U6-driven sgRNA targeting RPP29 (POP4 Human)

Use

CRISPR and Lentiviral

Available Since

Aug. 4, 2025

Availability

Academic Institutions and Nonprofits only

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SS18_IDR-EGFP

Plasmid

#232756

Purpose

Expresses SS18_IDR-EGFP

Depositor

Isaac Hilton

Article

Li et al Nucleic Acids Res. 2025 Feb 8;53(4):gkaf

Insert

SS18_IDR-EGFP (SS18 Human)

Use

Lentiviral

Promoter

EF1a

Available Since

April 15, 2025

Availability

Academic Institutions and Nonprofits only

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pSOX17-T2A-dTom-PGK-Neo

Plasmid

#223190

Purpose

Tomato reporter plasmid targeting the human SOX17 gene

Depositor

Matthew Birket

Article

Lynch et al EMBO J. 2025 Mar 31. doi: 10.1038/s44318

Insert

SOX17-T2A-dTomato-PGK-Neo-SOX17 (SOX17 Human)

Use

Cre/Lox; Human targeting

Available Since

April 1, 2025

Availability

Academic Institutions and Nonprofits only

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pBIG1a_GST-TEV-CK2alpha_CK2beta

Plasmid

#223740

Purpose

Expression of recombinant protein for purification

Depositor

Sascha Martens

Article

Adriaenssens et al Nat Cell Biol. 2025 Jul 25. doi: 10.1038

Insert

CK2-alpha, CK2-beta (CSNK2A1 Human)

Tags

GST-TEV

Expression

Insect

Available Since

March 25, 2025

Availability

Academic Institutions and Nonprofits only

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pLV-SFFV-myc-STIM2-WPRE-UbC-Emerald

Plasmid

#225940

Purpose

Lentiviral vector plasmid expressing human stromal interaction molecule 2 (STIM2) fused to myc-tag under the spleen focus-forming virus (SFFV) promoter and Emerald under the Ubiquitin C (UbC) promoter

Depositor

Richard Eva, Bart Nieuwenhuis, Evan Reid

Inserts

STIM2 (STIM2 Human)
Emerald

Use

Lentiviral

Tags

myc-tag

Expression

Mammalian

Promoter

SFFV and UbC

Available Since

Jan. 24, 2025

Availability

Academic Institutions and Nonprofits only

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pENTR1A 2xHA GPR153

Plasmid

#226808

Purpose

Gateway entry vector for 2xHA GPR153

Depositor

Ramiro Iglesias-Bartolome

Article

Pedro et al J Invest Dermatol. 2024 Jun;144(6):1311-

Insert

GPR153 (GPR153 Human)

Use

Gateway entry

Tags

2xHA tag followed by a GDPPVAT linker

Mutation

Sequence optimized from NP_997253.2

Available Since

Jan. 7, 2025

Availability

Academic Institutions and Nonprofits only

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pRetroX-TRE3G-GMIP P363D P364D P366D

Plasmid

#221323

Purpose

Dox-inducible expression of GMIP mutant in mammalian cells by retroviral transduction

Depositor

Jonathan Kagan

Article

Landau et al Mol Cell. 2024 Jul 11;84(13):2436-2454.e

Insert

GMIP (Gmip Mouse)

Use

Retroviral

Tags

3xFLAG

Mutation

P363D P364D P366D

Promoter

TRE3G

Available Since

July 17, 2024

Availability

Academic Institutions and Nonprofits only

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pAcGFP-N1_CBPKTG

Plasmid

#221911

Purpose

Transient expression of GFP-tagged CBPKTG in mammalian cells

Depositor

Daniel Bose

Article

Gelder et al Cell Rep. 2026 Mar 12;45(3):117109. doi:

Insert

CBP (CREBBP Human)

Tags

GFP

Expression

Mammalian

Mutation

mutation of lysine residues to glycine residues (…

Available Since

June 28, 2024

Availability

Academic Institutions and Nonprofits only

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pAcGFP-N1_CBPdCFIDdAL

Plasmid

#221916

Purpose

Transient expression of GFP-tagged CBPdeltaCFIDdeltaAL in mammalian cells

Depositor

Daniel Bose

Article

Gelder et al Cell Rep. 2026 Mar 12;45(3):117109. doi:

Insert

CBP (CREBBP Human)

Tags

GFP

Expression

Mammalian

Mutation

deletion of the CBP-FUS interaction domain (CFID)…

Available Since

June 28, 2024

Availability

Academic Institutions and Nonprofits only

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pAcGFP-N1_CBPdIDR6KTG

Plasmid

#221913

Purpose

Transient expression of GFP-tagged CBPdeltaIDR6KTG in mammalian cells

Depositor

Daniel Bose

Article

Gelder et al Cell Rep. 2026 Mar 12;45(3):117109. doi:

Insert

CBP (CREBBP Human)

Tags

GFP

Expression

Mammalian

Mutation

deletion of IDR6 (aa 1856 - 2090); mutation of ly…

Available Since

June 28, 2024

Availability

Academic Institutions and Nonprofits only

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pAcGFP-N1_CBPdIDR7KTG

Plasmid

#221915

Purpose

Transient expression of GFP-tagged CBPdeltaIDR7KTG in mammalian cells

Depositor

Daniel Bose

Article

Gelder et al Cell Rep. 2026 Mar 12;45(3):117109. doi:

Insert

CBP (CREBBP Human)

Tags

GFP

Expression

Mammalian

Mutation

deletion of IDR7 (aa 2109-2434); mutation of lysi…

Available Since

June 28, 2024

Availability

Academic Institutions and Nonprofits only

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H6Gb1-CREB(1-280) T2C, C90A, T198C

Plasmid

#220235

Purpose

bacterial expression of CREB1 domains

Depositor

Peter Wright

Article

Martinez-Yamout et al Proc Natl Acad Sci U S A. 2023 Nov 21;12

Insert

CREB1 (Creb1 Rat)

Tags

His6-GB1-tev

Expression

Bacterial

Mutation

T2C, C90A, T198C

Promoter

T7

Available Since

June 12, 2024

Availability

Academic Institutions and Nonprofits only

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