We narrowed to 3,090 results for: FRI

1. pcDNA3.1_ADAR2DD_E488Q

   Plasmid

   #205598

   Purpose

   expresses human ADAR2 deaminase domain (E488Q hyperactive mutant) in mammalian cells

   Depositor

   Marc Friedlander

   Article

   Sekar et al Nat Biotechnol. 2023 Sep 21. doi: 10.103

   Insert

   ADAR2 deaminase domain (ADARB1 Human)
   

   Use

   Tags

   Expression

   Mammalian

   Mutation

   E488Q hyperactive mutation

   Promoter

   Available since

   Oct. 2, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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2. GSK3betaS9A  (1016)

   Plasmid

   #49492

   Purpose

   expresses human Gsk3beta with S9A (constitutively active) mutation

   Depositor

   Scott Friedman

   Article

   Lang et al Oncogene. 2012 Oct 22. doi: 10.1038/onc.

   Insert

   GSK3beta S9A (GSK3B Human)
   

   Use

   Tags

   Expression

   Mammalian

   Mutation

   S9A (constitutively active)

   Promoter

   CMV

   Available since

   May 21, 2014

   Availability

   Academic Institutions and Nonprofits only

   

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3. pcDNA3.1_ADAR2DD_E488Q_Ago2

   Plasmid

   #205599

   Purpose

   expresses human ADAR2 deaminase domain (E488Q hyperactive mutant) fused with human Ago2 in mammalian cells

   Depositor

   Marc Friedlander

   Article

   Sekar et al Nat Biotechnol. 2023 Sep 21. doi: 10.103

   Insert

   hAgo2 (AGO2 Human)
   

   Use

   Tags

   ADAR2DD_E488Q (hyperactive mutant)

   Expression

   Mammalian

   Mutation

   Promoter

   Available since

   Oct. 2, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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4. pWPI-N3ICD

   Plasmid

   #185524

   Purpose

   Constitutive overexpression of human NOTCH3 intracellular domain

   Depositor

   Eric Shusta, Sean Palecek

   Article

   Gastfriend et al Sci Adv. 2024 Feb 2;10(5):eadi1737. doi:

   Insert

   NOTCH3 intracellular domain (NOTCH3 Human)
   

   Use

   Lentiviral

   Tags

   Expression

   Mutation

   Promoter

   EF-1a

   Available since

   Feb. 5, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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5. Ad-EphA3 KD

   Plasmid

   #102726

   Purpose

   Expression of Kinase dead EphA3

   Depositor

   Jin Chen

   Article

   Frieden et al Dev Dyn. 2010 Dec;239(12):3226-34. doi:

   Insert

   EphA3 (Epha3 Mouse)
   

   Use

   Adenoviral

   Tags

   Expression

   Mutation

   Kinase Dead (K657M; AAA > ATG)

   Promoter

   Available since

   March 20, 2018

   Availability

   Academic Institutions and Nonprofits only

   

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6. hu-TLR4 cDNA wt pDEST40

   Plasmid

   #42646

   Purpose

   destination vector for expression of human TLR4 in mammalian cells

   Depositor

   Scott Friedman

   Article

   Guo et al Hepatology. 2009 Mar;49(3):960-8. doi: 1

   Insert

   TLR4 (TLR4 Human)
   

   Use

   Tags

   Flag

   Expression

   Mammalian

   Mutation

   Promoter

   CMV

   Available since

   March 3, 2014

   Availability

   Academic Institutions and Nonprofits only

7. FERM domain of Ezrin

   Plasmid

   #62380

   Purpose

   Expresses the FERM domain of Ezrin (N terminal portion of the protein)

   Depositor

   Guillaume Charras

   Article

   Fritzsche et al Biophys J. 2014 Jan 21;106(2):343-53. do

   Insert

   Ezrin aa1-309 (EZR Human)
   

   Use

   Tags

   GFP

   Expression

   Mammalian

   Mutation

   contains FERM domain of Ezrin (N terminal portion…

   Promoter

   CMV

   Available since

   March 16, 2015

   Availability

   Academic Institutions and Nonprofits only

   

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8. FUG-T2A-Pten

   Plasmid

   #140738

   Purpose

   Lentiviral vector to overexpress human PTEN and GFP

   Depositor

   Bryan Luikart

   Article

   Fricano-Kugler et al Biol Psychiatry. 2018 Aug 15;84(4):265-2

   Insert

   GFP-PTA-PTEN (PTEN Human)
   

   Use

   Lentiviral

   Tags

   none

   Expression

   Mammalian

   Mutation

   Promoter

   hUbiC

   Available since

   May 4, 2020

   Availability

   Academic Institutions and Nonprofits only

   

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9. pAAV-IV-GFPL10

   Plasmid

   #98704

   Purpose

   Cre-dependently express GFPL10 fusion using Introvert Switch

   Depositor

   Alexander Nectow, Jeffrey Friedman

   Article

   Nectow et al Cell. 2017 Jul 27;170(3):429-442.e11. do

   Insert

   GFPL10
   

   Use

   AAV and Cre/Lox

   Tags

   GFP

   Expression

   Mammalian

   Mutation

   L10: 2609 C->T to remove EcoRI site

   Promoter

   EF1a

   Available since

   Aug. 7, 2017

   Availability

   Academic Institutions and Nonprofits only

   

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10. pGLB2 5'3'

    Plasmid

    #49346

    Purpose

    luciferase reporter with Bmp2 promoter (1702 bp) and Bmp2 3'UTR (2015 bp)

    Depositor

    Melissa Rogers

    Article

    Fritz et al J Biol Chem. 2004 Nov 19;279(47):48950-8

    Inserts

    Bmp2 distal promoter (Bmp2 Mouse)
    Bmp2 3' UTR (Bmp2 Mouse)
    

    Use

    Luciferase

    Tags

    luciferase

    Expression

    Mutation

    Promoter

    -

    Available since

    Dec. 9, 2013

    Availability

    Academic Institutions and Nonprofits only

11. pCRII-Plxnb2-ISH-2kb

    Plasmid

    #68036

    Purpose

    Contains 2kb cDNA fragment for probe synthesis for mRNA in situ hybridization, species: mouse

    Depositor

    Roland Friedel

    Article

    Maier et al Mol Cell Neurosci. 2011 Feb;46(2):419-31

    Insert

    Plexin-B2 (Plxnb2 Mouse)
    

    Use

    Mrna in situ hybridization probe

    Tags

    Expression

    Mutation

    Promoter

    Available since

    Aug. 27, 2015

    Availability

    Academic Institutions and Nonprofits only

    

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12. pUAS-CFP-MEK

    Plasmid

    #42077

    Depositor

    Norbert Perrimon

    Article

    Friedman et al Nature. 2006 Nov 9;444(7116):230-4. Epub

    Insert

    Drosophila MEK ortholog (Dsor1 Fly)
    

    Use

    Tags

    CFP

    Expression

    Insect

    Mutation

    Promoter

    Hsp70

    Available since

    March 6, 2013

    Availability

    Academic Institutions and Nonprofits only

13. pBABE-puroGFP-Eps8WT

    Plasmid

    #74956

    Purpose

    mammalian expression of Eps8 fused to GFP

    Depositor

    Giorgio Scita

    Article

    Frittoli et al Immunity. 2011 Sep 23;35(3):388-99. doi:

    Insert

    Eps8 (Eps8 Mouse)
    

    Use

    Tags

    EGFP

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    May 3, 2016

    Availability

    Academic Institutions and Nonprofits only

14. PE-pegRNA(BG)-nsgRNA(BG)

    Plasmid

    #232727

    Purpose

    A dual-targeting vector that contains PE3 system guide RNAs against BFP (pegRNA(BG) and nsgRNA(BG)) with restriction enzyme sites for insertion of target site guide RNAS (pegRNAs(TS) and nsgRNA(TS)).

    Depositor

    David Brafman

    Article

    Frisch et al Mol Ther Nucleic Acids. 2023 Jul 17;33:4

    Insert

    pegRNA(BG), nsgRNA(BG), pegRNAs(TS), nsgRNA(TS)
    

    Use

    CRISPR

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    U6

    Available since

    Feb. 20, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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15. FUG-T2A-H93R

    Plasmid

    #140739

    Purpose

    Lentiviral vector to overexpress the autism-associated PTEN mutation H93R and GFP as two separate proteins

    Depositor

    Bryan Luikart

    Article

    Fricano-Kugler et al Biol Psychiatry. 2018 Aug 15;84(4):265-2

    Insert

    GFP-T2A-PTENH93R (PTEN Human)
    

    Use

    Lentiviral

    Tags

    none

    Expression

    Mammalian

    Mutation

    H93R

    Promoter

    h

    Available since

    May 4, 2020

    Availability

    Academic Institutions and Nonprofits only

    

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16. FUG-PtenN276S

    Plasmid

    #140737

    Purpose

    Lentiviral vector to overexpress the PTEN mutation N276S as a GFP-PTEN fusion protein

    Depositor

    Bryan Luikart

    Article

    Fricano-Kugler et al Biol Psychiatry. 2018 Aug 15;84(4):265-2

    Insert

    PTEN – phosphatase and tensin homolog (PTEN Human)
    

    Use

    Lentiviral

    Tags

    GFP

    Expression

    Mammalian

    Mutation

    N276S

    Promoter

    hUbiC

    Available since

    May 4, 2020

    Availability

    Academic Institutions and Nonprofits only

    

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17. FUG-PtenW274L

    Plasmid

    #140736

    Purpose

    Lentiviral vector to overexpress the autism-associated PTEN mutation W274L as a GFP-PTEN fusion protein

    Depositor

    Bryan Luikart

    Article

    Fricano-Kugler et al Biol Psychiatry. 2018 Aug 15;84(4):265-2

    Insert

    GFP-PTEN (PTEN Human)
    

    Use

    Lentiviral

    Tags

    GFP

    Expression

    Mammalian

    Mutation

    W274L

    Promoter

    hUbiC

    Available since

    May 4, 2020

    Availability

    Academic Institutions and Nonprofits only

    

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18. FUG-PtenD252G

    Plasmid

    #140735

    Purpose

    Lentiviral vector to overexpress the autism-associated PTEN mutation D252G as a GFP-PTEN fusion protein

    Depositor

    Bryan Luikart

    Article

    Fricano-Kugler et al Biol Psychiatry. 2018 Aug 15;84(4):265-2

    Insert

    GFP-PTEN (PTEN Human)
    

    Use

    Lentiviral

    Tags

    GFP

    Expression

    Mammalian

    Mutation

    D252G

    Promoter

    hUbiC

    Available since

    May 4, 2020

    Availability

    Academic Institutions and Nonprofits only

    

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19. FUG-PtenH93R

    Plasmid

    #140733

    Purpose

    Lentiviral vector to overexpress the autism-associated PTEN mutation H93R as a GFP-PTEN fusion protein

    Depositor

    Bryan Luikart

    Article

    Fricano-Kugler et al Biol Psychiatry. 2018 Aug 15;84(4):265-2

    Insert

    GFP-PTEN (PTEN Human)
    

    Use

    Lentiviral

    Tags

    GFP

    Expression

    Mammalian

    Mutation

    H93R

    Promoter

    hUbiC

    Available since

    May 4, 2020

    Availability

    Academic Institutions and Nonprofits only

    

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20. pLenti-PGK-Venus-Fluc (puro)

    Plasmid

    #140328

    Purpose

    Lentivirus for expression of Venus-Fluc (firefly luciferase) fusion protein

    Depositor

    Roland Friedel

    Article

    Bozec et al Neurooncol Adv. 2020 Oct 10;2(1):vdaa134

    Insert

    Venus-Firefly Luciferase (luc2)
    

    Use

    Lentiviral

    Tags

    Expression

    Mutation

    Promoter

    human PGK promoter

    Available since

    Sept. 21, 2020

    Availability

    Academic Institutions and Nonprofits only

    

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