We narrowed to 11,199 results for: AGA

1. pGMC00005

   Plasmid

   #166722

   Purpose

   sgRNA against human ASNS

   Depositor

   Raj Chari

   Article

   Ruiz-Rodado et al Cancer Metab. 2020 Oct 21;8:23. doi: 10.

   Insert

   ASNS (ASNS Human)
   

   Use

   CRISPR and Lentiviral

   Expression

   Mammalian

   Available Since

   June 9, 2021

   Availability

   Academic Institutions and Nonprofits only

   

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2. pLenti-Puro-sgAMPKa2

   Plasmid

   #138685

   Purpose

   Expresses a human AMPKa2-targeting sgRNA and Cas9

   Depositor

   Reuben Shaw

   Article

   Hollstein et al Cancer Discov. 2019 Nov;9(11):1606-1627.

   Insert

   sgAMPKa2 human (PRKAA2 Human)
   

   Use

   Lentiviral

   Promoter

   hU6

   Available Since

   Feb. 26, 2020

   Availability

   Academic Institutions and Nonprofits only

   

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3. pLKO-Tet-On-PLXNB2-shRNA1

   Plasmid

   #98399

   Purpose

   Lentivirus for expression of shRNA1 against human PLEXIN-B2 (Dox-inducible)

   Depositor

   Roland Friedel

   Article

   Junqueira Alves et al Nat Commun. 2021 Oct 14;12(1):6019. doi:

   Insert

   Plexin-B2 (PLXNB2 Human)
   

   Use

   Lentiviral

   Available Since

   July 12, 2017

   Availability

   Academic Institutions and Nonprofits only

   

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4. pAAV-Ef1a DIO-hsChRmine-oScarlet-Kv2.1-WPRE

   Plasmid

   #183527

   Purpose

   Optogenetics

   Depositor

   Karl Deisseroth

   Article

   Kishi et al Cell. 2022 Feb 17;185(4):672-689.e23. do

   Insert

   hsChRmine-oScarlet-Kv2.1
   

   Use

   AAV

   Mutation

   H33R

   Promoter

   Ef1a

   Available Since

   Aug. 2, 2022

   Availability

   Academic Institutions and Nonprofits only

   

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5. pX458_mCherry-EWSR1-gRNA

   Plasmid

   #237683

   Purpose

   Cas9 from S. pyogenes with 2A-mCherry, gRNA to knock-in msfGFP to EWSR1 locus

   Depositor

   Denes Hnisz

   Article

   Zhang et al Nature. 2025 Jun 4. doi: 10.1038/s41586-

   Insert

   EWSR1 gRNA (EWSR1 Human)
   

   Use

   CRISPR

   Tags

   mCherry

   Available Since

   May 6, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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6. pT2/shCol1a1/GFP4_Seq1.3

   Plasmid

   #206136

   Purpose

   Knockdown of Collagen Type 1 alpha 1. Construct has inverted repeats to be used in Sleeping Beauty transposon system.

   Depositor

   Maria Castro

   Article

   Comba et al Nat Commun. 2022 Jun 24;13(1):3606. doi:

   Insert

   COL1A1 (Col1a1 Mouse)
   

   Expression

   Mammalian

   Available Since

   Sept. 11, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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7. pIS1 mLPIN1

   Plasmid

   #60803

   Purpose

   Luciferase reporter to measure miR-155 mediated differential repression. Contains LPIN1 3' UTR and mutated miR-155 sites

   Depositor

   David Bartel

   Article

   Nam et al Mol Cell. 2014 Mar 20;53(6):1031-43. doi

   Insert

   LPIN1 3'UTR and mutated miR-155 binding site (LPIN1 Human)
   

   Use

   Luciferase

   Expression

   Mammalian

   Mutation

   mutated miR-155 binding site

   Promoter

   thymidine kinase (HSV-TK promoter)

   Available Since

   Oct. 20, 2014

   Availability

   Academic Institutions and Nonprofits only

   

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8. pLKO.1-puro-Nono-sh1

   Plasmid

   #127650

   Purpose

   Knock-down of human NONO

   Depositor

   Nicolas Manel

   Article

   Lahaye et al Cell. 2018 Oct 4;175(2):488-501.e22. doi

   Insert

   NONO shRNA (NONO Human)
   

   Use

   Lentiviral

   Available Since

   July 11, 2019

   Availability

   Academic Institutions and Nonprofits only

   

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9. hSyn-HA-PGRN-LAMP1TM-IRES-GFP

   Plasmid

   #234877

   Purpose

   Lentiviral plasmid expressing HA-tagged human progranulin that is fused to the transmembrane domain and cytosolic tail of LAMP-1. Enables lysosomal delivery of progranulin without secretion.

   Depositor

   Andrew Arrant

   Article

   Davis et al J Biol Chem. 2021 Sep;297(3):100993. doi

   Insert

   Progranulin (GRN Human)
   

   Use

   Lentiviral

   Tags

   HA tag and LAMP-1 transmembrane domain and cytoso…

   Expression

   Mammalian

   Promoter

   hSYn

   Available Since

   April 24, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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10. pRK5_mEGFP-SS18-SSX2

    Plasmid

    #237637

    Purpose

    For overexpression of mEGFP-SS18-SSX2

    Depositor

    Denes Hnisz

    Article

    Zhang et al Nature. 2025 Jun 4. doi: 10.1038/s41586-

    Insert

    SS18-SSX2 (SS18, SSX2 Human)
    

    Tags

    mEGFP

    Expression

    Mammalian

    Available Since

    May 6, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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11. TERT - R865C

    Plasmid

    #213926

    Purpose

    Expresses Mutant TERT R865C

    Depositor

    Coleman Lindsley

    Article

    Reilly et al Blood. 2021 Sep 9;138(10):898-911. doi:

    Insert

    Mutant TERT R865C (TERT Human)
    

    Use

    Lentiviral

    Tags

    6x His Tag

    Expression

    Mammalian

    Mutation

    Arginine 865 changed to Cysteine

    Promoter

    Tet-responsive promoter PTight, consisting of sev…

    Available Since

    Feb. 21, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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12. pUB6_EZH2

    Plasmid

    #84014

    Purpose

    EZH2 minigene to test splicing event

    Depositor

    Robert Bradley

    Article

    Kim et al Cancer Cell. 2015 May 11;27(5):617-30. d

    Insert

    EZH2 (EZH2 Human)
    

    Expression

    Mammalian

    Promoter

    UB6

    Available Since

    Oct. 17, 2016

    Availability

    Academic Institutions and Nonprofits only

    

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13. LMP AMPK alpha1 hp1

    Plasmid

    #89489

    Purpose

    shRNA against AMPK alpha1 in mouse/human to knock down protein expression

    Depositor

    Russell Jones

    Article

    Faubert et al Cell Metab. 2013 Jan 8;17(1):113-24. doi

    Insert

    hairpin against mouse/human AMPKalpha1 (PRKAA1, Prkaa1 Human, Mouse)
    

    Use

    Mouse Targeting and Retroviral

    Expression

    Mammalian

    Promoter

    U6 (The GFP-Puro is from a PGK promoter; the shRN…

    Available Since

    May 19, 2017

    Availability

    Academic Institutions and Nonprofits only

14. CDK16 gRNA (BRDN0001147125)

    Plasmid

    #76903

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human CDK16

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    CDK16 (CDK16 Human)
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Promoter

    hU6

    Available Since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

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15. CDK16 gRNA (BRDN0001147123)

    Plasmid

    #76902

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human CDK16

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    CDK16 (CDK16 Human)
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Promoter

    hU6

    Available Since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

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16. pRP.CEP290 c.2991+1655A>G

    Plasmid

    #226556

    Purpose

    Minigene encoding the CEP290 c.2991+1655A>G mutation

    Depositor

    Dave Wee

    Article

    Tabaglio et al Mol Ther Nucleic Acids. 2025 Jan 7;36(1)

    Insert

    CEP290 (CEP290 Human)
    

    Tags

    3xFLAG

    Expression

    Mammalian

    Mutation

    c.2991+1655A>G intronic mutation

    Available Since

    Jan. 13, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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17. B270 + SMARCAL1 sgSTOP

    Plasmid

    #100717

    Purpose

    B270 plasmid expressing SMARCAL1 sgSTOP (cloned in BbsI site) in combination with ATP1A1 sgSTOP

    Depositor

    Alberto Ciccia

    Article

    Billon et al Mol Cell. 2017 Sep 4. pii: S1097-2765(17

    Insert

    sgSTOP targeting SMARCAL1 (cloned using BbsI) and ATP1A1 (SMARCAL1 Human)
    

    Use

    CRISPR

    Expression

    Mammalian

    Promoter

    U6 promoters

    Available Since

    Sept. 6, 2017

    Availability

    Academic Institutions and Nonprofits only

    

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18. plentiCRISPRv2-PURO-LYSET-gRNA1

    Plasmid

    #210489

    Purpose

    CRISPR pooled KO of human LYSET

    Depositor

    Jan Carette

    Article

    Richards et al Science. 2022 Sep 8:eabn5648. doi: 10.11

    Insert

    LYSET-gRNA1 (LYSET Human)
    

    Use

    CRISPR and Lentiviral

    Available Since

    Nov. 30, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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19. plentiCRISPRv2-PURO-LYSET-gRNA2

    Plasmid

    #210490

    Purpose

    CRISPR pooled KO of human LYSET

    Depositor

    Jan Carette

    Article

    Richards et al Science. 2022 Sep 8:eabn5648. doi: 10.11

    Insert

    LYSET-gRNA2 (LYSET Human)
    

    Use

    CRISPR and Lentiviral

    Available Since

    Nov. 30, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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20. FUW-Flag-Mbd3

    Plasmid

    #52371

    Purpose

    Lentiviral expression vector for constitutive expression of double Flag tagged Mbd3

    Depositor

    Jacob Hanna

    Article

    Rais et al Nature. 2013 Oct 3;502(7469):65-70. doi:

    Insert

    Mbd3 (Mbd3 Mouse)
    

    Use

    Lentiviral

    Tags

    flag

    Expression

    Mammalian

    Promoter

    Ub

    Available Since

    Sept. 8, 2014

    Availability

    Academic Institutions and Nonprofits only

    

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