Purpose
Stable expression of EGFP-LOV2(G528A, N538E)-BAX-TMEM106B in mammalian cells. Photoactivatable BAX localizes on lysosomal membrane and induces lysosomal rupture upon blue light stimulation.
Inserts
LOV2 domain of phototropin1
BAX (
BAX Human)
TMEM106B (
TMEM106B Human)
Mutation
N-terminus and C-terminus are deleted. BAX(3-171)…
Available Since
April 28, 2025
Availability
Academic Institutions and Nonprofits only