We narrowed to 12,185 results for: SHA

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pCAG-HP1β-I161E-EGFP

Plasmid

#179939

Purpose

C terminal fusion of EGFP to mouse HP1β (Cbx1) containing I161E mutation

Depositor

Andrew Newman

Article

Newman et al Nat Commun. 2025 Aug 8;16(1):7325. doi:

Insert

Cbx 1 (Cbx1 Mouse)

Tags

EGFP

Expression

Mammalian

Mutation

I161E

Available Since

Oct. 3, 2025

Availability

Academic Institutions and Nonprofits only

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pDisplay-CMV-GRAB_LoX3-1.0

Plasmid

#234650

Purpose

This plasmid encodes a genetically encoded fluorescent biosensor based on human CXCR3 for chemokine CXCL9-11 detection.

Depositor

Miao Jing

Article

Xi et al Immunity. 2025 Sep 9;58(9):2320-2335.e9.

Insert

GPCR activation based chemokine CXCL9-11 sensor GRAB_LoX3-1.0 (CXCR3 Human)

Expression

Mammalian

Promoter

CMV

Available Since

Aug. 12, 2025

Availability

Academic Institutions and Nonprofits only

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TOPO-EXOC3 MIDDLE 300BP

Plasmid

#226440

Purpose

For subcloning of human EXOC3 promoter (middle 300 bp) or for assays using M13 phage

Depositor

Glen Borchert

Article

DeMeis et al Nucleic Acids Res. 2025 Jan 11;53(2):gka

Insert

EXOC3 MIDDLE 300BP (EXOC3 Human)

Use

Cloning vector

Mutation

No

Available Since

July 14, 2025

Availability

Academic Institutions and Nonprofits only

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TOPO-EXOC3 3' HALF

Plasmid

#226439

Purpose

For subcloning of human EXOC3 promoter (3' half) or for assays using M13 phage

Depositor

Glen Borchert

Article

DeMeis et al Nucleic Acids Res. 2025 Jan 11;53(2):gka

Insert

EXOC3 3' HALF (EXOC3 Human)

Use

Cloning vector

Mutation

No

Available Since

July 14, 2025

Availability

Academic Institutions and Nonprofits only

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TOPO-EXOC3 5' HALF

Plasmid

#226438

Purpose

For subcloning of human EXOC3 promoter (5' half) or for assays using M13 phage

Depositor

Glen Borchert

Article

DeMeis et al Nucleic Acids Res. 2025 Jan 11;53(2):gka

Insert

EXOC3 5' HALF (EXOC3 Human)

Use

Cloning vector

Mutation

No

Available Since

July 14, 2025

Availability

Academic Institutions and Nonprofits only

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pGL4.10 promEXOC3

Plasmid

#205467

Purpose

Luciferase reporter of promoter activity

Depositor

Glen Borchert

Article

DeMeis et al Nucleic Acids Res. 2025 Jan 11;53(2):gka

Insert

EXOC3 Promoter (EXOC3 Human)

Use

Luciferase

Promoter

EXOC3

Available Since

July 2, 2025

Availability

Academic Institutions and Nonprofits only

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DHFR-C-HiBiT

Plasmid

#207119

Purpose

Bacterially expressed DHFR-HiBiT for Ni-NTA purification

Depositor

James Inglese

Article

Ciulla et al Nat Commun. 2025 May 10;16(1):4342. doi:

Insert

Human-dihydrofolate reductase-HiBiT-10xHis (DHFR Human)

Tags

10xHis-tag and HiBiT tag

Expression

Bacterial

Mutation

Codon optmization for expression in BL21DE3

Promoter

T7

Available Since

May 13, 2025

Availability

Academic Institutions and Nonprofits only

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pX458_mCherry-HP1a-gRNA-2

Plasmid

#237635

Purpose

Cas9 from S. pyogenes with 2A-mCherry, gRNA to knock-in msfGFP to HP1a locus

Depositor

Denes Hnisz

Article

Zhang et al Nature. 2025 Jun 4. doi: 10.1038/s41586-

Insert

HP1a gRNA (CBX5 Human)

Use

CRISPR

Tags

mCherry

Available Since

May 6, 2025

Availability

Academic Institutions and Nonprofits only

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pRK5_mEGFP-SS18-SSX1-KS

Plasmid

#237679

Purpose

For overexpression of mEGFP-SS18-SSX1-KS

Depositor

Denes Hnisz

Article

Zhang et al Nature. 2025 Jun 4. doi: 10.1038/s41586-

Insert

SS18-SSX1-KS (SS18, SSX1 Human)

Tags

mEGFP

Expression

Mammalian

Available Since

May 6, 2025

Availability

Academic Institutions and Nonprofits only

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pRK5_mEGFP-SS18-SSX1

Plasmid

#237678

Purpose

For overexpression of mEGFP-SS18-SSX1

Depositor

Denes Hnisz

Article

Zhang et al Nature. 2025 Jun 4. doi: 10.1038/s41586-

Insert

SS18-SSX1 (SS18, SSX1 Human)

Tags

mEGFP

Expression

Mammalian

Available Since

May 6, 2025

Availability

Academic Institutions and Nonprofits only

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pRK5_mEGFP-SS18-SSX2-KS

Plasmid

#237680

Purpose

For overexpression of mEGFP-SS18-SSX2-KS

Depositor

Denes Hnisz

Article

Zhang et al Nature. 2025 Jun 4. doi: 10.1038/s41586-

Insert

SS18-SSX2-KS (SS18, SSX2 Human)

Tags

mEGFP

Expression

Mammalian

Available Since

May 6, 2025

Availability

Academic Institutions and Nonprofits only

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pX458_mCherry-HP1a-gRNA-1

Plasmid

#237634

Purpose

Cas9 from S. pyogenes with 2A-mCherry, gRNA to knock-in msfGFP to HP1a locus

Depositor

Denes Hnisz

Article

Zhang et al Nature. 2025 Jun 4. doi: 10.1038/s41586-

Insert

HP1a gRNA (CBX5 Human)

Use

CRISPR

Tags

mCherry

Available Since

May 6, 2025

Availability

Academic Institutions and Nonprofits only

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pX458_mCherry-TCOF1-gRNA

Plasmid

#237633

Purpose

Cas9 from S. pyogenes with 2A-mCherry, gRNA to knock-in msfGFP to TCOF1 locus

Depositor

Denes Hnisz

Article

Zhang et al Nature. 2025 Jun 4. doi: 10.1038/s41586-

Insert

TCOF1 gRNA (TCOF1 Human)

Use

CRISPR

Tags

mCherry

Available Since

May 6, 2025

Availability

Academic Institutions and Nonprofits only

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pUC19_msfGFP-FUS-repair-tempate

Plasmid

#237684

Purpose

For knock-in msfGFP to FUS locus

Depositor

Denes Hnisz

Article

Zhang et al Nature. 2025 Jun 4. doi: 10.1038/s41586-

Insert

FUS (FUS Human)

Use

CRISPR

Tags

msfGFP

Available Since

May 6, 2025

Availability

Academic Institutions and Nonprofits only

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MKC84_HBB(HBA1reg-HBA1)

Plasmid

#232410

Purpose

AAV production plasmid for HBA1 UTRs vector from Fig. 3 that mediates HDR at HBB locus using HBB sg7 gRNA. HBA gene includes HBA1 exons and introns; HBA1 UTRs flank HBA1 cassette.

Depositor

Kyle Cromer

Article

Chu et al bioRxiv [Preprint]. 2024 May 7:2023.09.0

Insert

Hemoglobin Subunit Alpha 1 (HBA1 Human)

Use

AAV

Expression

Mammalian

Available Since

April 18, 2025

Availability

Academic Institutions and Nonprofits only

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MKC83_HBB(HBBreg-HBA1)

Plasmid

#232409

Purpose

AAV production plasmid for HBB UTRs vector from Fig. 3 that mediates HDR at HBB locus using HBB sg7 gRNA. HBA gene includes HBA1 exons and introns; HBB UTRs flank HBA1 cassette.

Depositor

Kyle Cromer

Article

Chu et al bioRxiv [Preprint]. 2024 May 7:2023.09.0

Insert

Hemoglobin Subunit Alpha 1 (HBA1 Human)

Use

AAV

Expression

Mammalian

Available Since

April 18, 2025

Availability

Academic Institutions and Nonprofits only

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pT3TS-RfxCas13d-hei

Plasmid

#234485

Purpose

Plasmid to carry out IVT of RfxCas13d with myc tag and two oNLS (human codon-optimized)

Depositor

Miguel Angel Moreno-Mateos

Article

Moreno-Sanchez et al Nat Commun. 2025 Mar 16;16(1):2591. doi:

Insert

RfxCas13d

Use

CRISPR

Tags

myc and oNLS

Available Since

April 11, 2025

Availability

Academic Institutions and Nonprofits only

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pLX313_PELO_WT

Plasmid

#228938

Purpose

Constitutive expression of wild-type human PELO

Depositor

Francisca Vazquez

Article

Borck et al Nature. 2025 Feb 5. doi: 10.1038/s41586-

Insert

PELO (PELO Human)

Use

Lentiviral

Expression

Mammalian

Available Since

April 3, 2025

Availability

Academic Institutions and Nonprofits only

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pLentiCRISPR V2 Neo PTEN sgRNA5

Plasmid

#233246

Purpose

Knock out of murine PTEN

Depositor

David Bryant

Article

Nikolatou et al EMBO J. 2023 Sep 18;42(18):e113987. doi:

Insert

PTEN (Pten Mouse)

Use

Lentiviral

Available Since

March 20, 2025

Availability

Academic Institutions and Nonprofits only

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pXPR_BRD051d_sgCiPELO #2

Plasmid

#229018

Purpose

Expression of CRISPRi PELO sgRNA #2

Depositor

Francisca Vazquez

Article

Borck et al Nature. 2025 Feb 5. doi: 10.1038/s41586-

Insert

PELO (PELO Human)

Use

CRISPR

Expression

Mammalian

Available Since

March 20, 2025

Availability

Academic Institutions and Nonprofits only

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