We narrowed to 18 results for: SHA

1. TP53 MITE Library

   Pooled Library

   #113569

   Purpose

   Pooled lentiviral plasmid library containing ~8,000 single amino acid substitution and nonsense mutant variants of p53

   Depositor

   David Root, William Hahn

   Article

   Giacomelli et al Nat Genet. 2018 Oct;50(10):1381-1387. do

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   Lentiviral

   Available since

   Jan. 4, 2019

   Availability

   Academic Institutions and Nonprofits only

2. Lenti-human-TF-gRNA-puromycin

   Pooled Library

   #162275

   Purpose

   This is a gRNA library targeting on ~1600 human transcription factors for genetic screening.

   Depositor

   Chunliang Li

   Article

   Zhang et al Elife. 2020 Oct 1;9. pii: 57858. doi: 10

   Species

   Homo sapiens

   Use

   Lentiviral

   Available since

   Dec. 15, 2020

   Availability

   Academic Institutions and Nonprofits only

3. Mouse sphingolipid metabolism knockout library

   Pooled Library

   #206249

   Purpose

   The sphingolipid metabolism library targets 82 mouse genes in the de novo ceramide and downstream sphingolipid metabolism pathways.

   Depositor

   Kivanc Birsoy

   Article

   Soula et al Nature. 2024 Aug 7. doi: 10.1038/s41586-

   Use

   CRISPR and Lentiviral

   Available since

   Aug. 29, 2024

   Availability

   Academic Institutions and Nonprofits only

4. Mini-human AsCpf1-based human genome-wide knockout library

   Pooled Library

   #130630

   Purpose

   Expresses crRNAs for genome-wide knockout pooled library screening

   Depositor

   Giulio Draetta

   Article

   Liu et al Nat Commun. 2019 Jul 17;10(1):3144. doi:

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   CRISPR and Lentiviral

   Available since

   Sept. 9, 2019

   Availability

   Academic Institutions and Nonprofits only

5. Mouse lipid metabolism knockout library

   Pooled Library

   #206248

   Purpose

   The lipid metabolism library contains guide RNAs against 295 genes targeting mouse genes encoding enzymes that directly impact lipid metabolism.

   Depositor

   Kivanc Birsoy

   Article

   Soula et al Nature. 2024 Aug 7. doi: 10.1038/s41586-

   Use

   CRISPR and Lentiviral

   Available since

   Aug. 29, 2024

   Availability

   Academic Institutions and Nonprofits only

6. TBG-mTSG

   Pooled Library

   #113585

   Purpose

   AAV-CRISPR library for pool mutagenesis of top tumor suppressor genes in mouse liver

   Depositor

   Sidi Chen

   Article

   Wang et al Sci Adv. 2018 Feb 28;4(2):eaao5508. doi:

   Expression

   Mammalian

   Use

   AAV, CRISPR, Lentiviral, and Luciferase

   Available since

   July 23, 2019

   Availability

   Academic Institutions and Nonprofits only

7. lentiGuide-Puro-pKO-library

   Pooled Library

   #190744

   Purpose

   CRISPR/Cas9 paired-guide RNA library to delete proximal poly(A) sites in mouse melanoma.

   Depositor

   Robert Bradley

   Article

   Gabel et al Nat Commun. 2024 Feb 1;15(1):959. doi: 1

   Expression

   Mammalian

   Species

   Mus musculus

   Use

   CRISPR, Lentiviral, and Mouse Targeting

   Available since

   Feb. 2, 2024

   Availability

   Academic Institutions and Nonprofits only

8. EFS-mTSG

   Pooled Library

   #113584

   Purpose

   AAV-CRISPR library for pool mutagenesis of top tumor suppressor genes

   Depositor

   Sidi Chen

   Article

   Wang et al Sci Adv. 2018 Feb 28;4(2):eaao5508. doi:

   Expression

   Mammalian

   Use

   AAV, CRISPR, Lentiviral, and Luciferase

   Available since

   July 23, 2019

   Availability

   Academic Institutions and Nonprofits only

9. MinLibCas9

   Pooled Library

   #164896

   Purpose

   Human genome-wide CRISPR-Cas9 gRNA library, optimised by mining existing large-scale screening datasets, which provides a >60% reduction in size while preserving key information content

   Depositor

   Mathew Garnett

   Article

   Gonçalves et al Genome Biol. 2021 Jan 21;22(1):40. doi:

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   CRISPR and Lentiviral

   Available since

   May 20, 2021

   Availability

   Academic Institutions and Nonprofits only

10. ClonTracer Barcoding Library (2.5 ug)

    Pooled Library

    #67267

    Purpose

    High complexity 30bp-long semi random DNA barcode library in lentiviral backbone

    Depositor

    Frank Stegmeier

    Article

    Bhang et al Nat Med. 2015 Apr 13. doi: 10.1038/nm.38

    Expression

    Mammalian

    Species

    Synthetic

    Use

    Lentiviral

    Available since

    Sept. 11, 2015

    Availability

    Academic Institutions and Nonprofits only

11. ClonTracer Barcoding Library (7.5 ug)

    Pooled Library

    #69830

    Purpose

    High complexity 30bp-long semi random DNA barcode library in lentiviral backbone

    Depositor

    Frank Stegmeier

    Article

    Bhang et al Nat Med. 2015 Apr 13. doi: 10.1038/nm.38

    Expression

    Mammalian

    Species

    Synthetic

    Use

    Lentiviral

    Available since

    Sept. 11, 2015

    Availability

    Academic Institutions and Nonprofits only

12. Human CRISPR Poison Exon Knockout Library

    Pooled Library

    #138084

    Purpose

    The human pgPoison library induces skipping of “poison” cassette exons and corresponding upstream constitutive exons by targeting 3' splice sites with paired gRNAs (pgRNAs).

    Depositor

    Robert Bradley

    Article

    Thomas et al Nat Genet. 2020 Jan;52(1):84-94. doi: 10

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available since

    March 6, 2020

    Availability

    Academic Institutions and Nonprofits only

13. HR700_TP53Exon5mut

    Pooled Library

    #229137

    Purpose

    Donor vector library to introduce TP53 mutations into the endogenous gene locus at exon 5 of human cells via CRISPR-HDR.

    Depositor

    Thorsten Stiewe

    Article

    Funk et al Nat Genet. 2025 Jan;57(1):140-153. doi:

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    CRISPR and Cre/Lox

    Available since

    Feb. 24, 2025

    Availability

    Industry, Academic Institutions, and Nonprofits

14. HR700_TP53Exon6mut

    Pooled Library

    #229138

    Purpose

    Donor vector library to introduce TP53 mutations into the endogenous gene locus at exon 6 of human cells via CRISPR-HDR.

    Depositor

    Thorsten Stiewe

    Article

    Funk et al Nat Genet. 2025 Jan;57(1):140-153. doi:

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    CRISPR and Cre/Lox

    Available since

    Feb. 24, 2025

    Availability

    Industry, Academic Institutions, and Nonprofits

15. HR700_TP53Exon7mut

    Pooled Library

    #229139

    Purpose

    Donor vector library to introduce TP53 mutations into the endogenous gene locus at exon 7 of human cells via CRISPR-HDR.

    Depositor

    Thorsten Stiewe

    Article

    Funk et al Nat Genet. 2025 Jan;57(1):140-153. doi:

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    CRISPR and Cre/Lox

    Available since

    Feb. 24, 2025

    Availability

    Industry, Academic Institutions, and Nonprofits

16. HR700_TP53Exon8mut

    Pooled Library

    #229140

    Purpose

    Donor vector library to introduce TP53 mutations into the endogenous gene locus at exon 8 of human cells via CRISPR-HDR.

    Depositor

    Thorsten Stiewe

    Article

    Funk et al Nat Genet. 2025 Jan;57(1):140-153. doi:

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    CRISPR and Cre/Lox

    Available since

    Feb. 24, 2025

    Availability

    Industry, Academic Institutions, and Nonprofits

17. pEPIP_PepTile_40merFragments_65CancerDrivers

    Pooled Library

    #172109

    Purpose

    Lentiviral peptide expression library for overexpression fitness screening

    Depositor

    Prashant Mali

    Article

    Ford et al Cell Syst. 2021 Jul 21;12(7):716-732.e7.

    Use

    Lentiviral

    Available since

    Oct. 21, 2021

    Availability

    Academic Institutions and Nonprofits only

18. Pan-Druggable Cancer Library

    Pooled Library

    #182133

    Purpose

    All-in-one CRISPR/Cas system with 74 individual elements. 63 elements target cancer-related genes with FDA-approved drug treatments, and 3 elements target key medulloblastoma driver genes.

    Depositor

    Prashant Mali

    Article

    Hu et al Biomaterials. 2022 Jan;280:121276. doi:

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available since

    Aug. 26, 2022

    Availability

    Academic Institutions and Nonprofits only