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pLVX-M-Flag-BAP1-H169Q

Plasmid

#125847

Purpose

express mutant BAP1-H169Q

Depositor

Boyi Gan

Article

Zhang et al Nat Cell Biol. 2018 Oct;20(10):1181-1192

Insert

BAP1 (BRCA1 associated protein 1) (BAP1 Human)

Use

Lentiviral

Tags

Flag

Mutation

H169Q

Available Since

June 5, 2019

Availability

Academic Institutions and Nonprofits only

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AAV-aCamkII-mCherry-P2A-Cre-WPRE-BGH-polyA

Plasmid

#107313

Purpose

Encoding aCamkII-mCherry-Cre

Depositor

Hui Yang

Article

Zhou et al Nat Neurosci. 2018 Jan 15. pii: 10.1038/

Insert

aCamkII-mCherry-P2A-Cre-WPRE-BGH-polyA

Use

AAV

Expression

Mammalian

Available Since

March 7, 2019

Availability

Academic Institutions and Nonprofits only

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pCMV-dCas12a-ABE8e

Plasmid

#193645

Purpose

Expression of base editor dCas12a-ABE8e in mammalian cells for base editing, along with non-fused EGFP fluorescence

Depositor

Liangxue Lai

Article

Chen et al Commun Biol. 2022 Nov 2;5(1):1163. doi:

Insert

dLbCas12a-TadA*8e, EGFP

Expression

Mammalian

Promoter

CMV

Available Since

Feb. 20, 2024

Availability

Academic Institutions and Nonprofits only

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Cas12Max

Plasmid

#195334

Purpose

vector for encoding a human codon-optimized Cas12Max driven by CBh promoter, guide RNAs compatible with xCas12i driven by hU6, and mCherry driven by CMV promoter

Depositor

Yingsi Zhou

Article

Zhang et al Protein Cell. 2023 Jun 28;14(7):538-543.

Insert

human codon-optimized Cas12Max

Tags

3xFlag

Expression

Mammalian

Mutation

N243R

Promoter

CBh, CMV, hU6

Available Since

Jan. 30, 2023

Availability

Academic Institutions and Nonprofits only

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pAAV-GfaABC1D-cOpn5-T2A-EGFP

Plasmid

#237859

Purpose

The transfer plasmid for packaging AAV expressing chicken OPN5 was constructed by inserting the OPN5 coding sequence into the multiple cloning site under the control of GfaABC1D promoter

Depositor

Minmin Luo

Article

Dai et al Sci China Life Sci. 2022 Jul;65(7):1271-

Insert

Opn5 (OPN5 Chicken)

Use

AAV

Promoter

GfaABC1D

Available Since

Aug. 25, 2025

Availability

Academic Institutions and Nonprofits only

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lentiCRISPR v2-sgBAP1-1

Plasmid

#125837

Purpose

KO BAP1 gene

Depositor

Boyi Gan

Article

Zhang et al Nat Cell Biol. 2018 Oct;20(10):1181-1192

Insert

BAP1 (BRCA1 associated protein 1) (BAP1 Human)

Use

Lentiviral

Available Since

June 5, 2019

Availability

Academic Institutions and Nonprofits only

Enlarge
pRDA355_sgCiPELO #2

Plasmid

#229020

Purpose

Expression of a CRISPRi doxycycline inducible guide targeting PELO

Depositor

Francisca Vazquez

Article

Borck et al Nature. 2025 Feb 5. doi: 10.1038/s41586-

Insert

PELO gRNA

Use

CRISPR and Lentiviral

Expression

Mammalian

Available Since

April 3, 2025

Availability

Academic Institutions and Nonprofits only

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pCMV-dCas12a-A3A-Y132D

Plasmid

#193641

Purpose

Expression of base editor dCas12a-A3A-Y132D in mammalian cells for base editing

Depositor

Liangxue Lai

Article

Chen et al Commun Biol. 2022 Nov 2;5(1):1163. doi:

Insert

dLbCas12a-hA3A-Y132D

Expression

Mammalian

Mutation

hAPOBEC3A-Y132D

Promoter

CMV

Available Since

Feb. 20, 2024

Availability

Academic Institutions and Nonprofits only

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lentiCRISPR v2-sgBAP1-2

Plasmid

#125838

Purpose

KO BAP1 gene

Depositor

Boyi Gan

Article

Zhang et al Nat Cell Biol. 2018 Oct;20(10):1181-1192

Insert

BAP1 (BRCA1 associated protein 1) (BAP1 Human)

Use

Lentiviral

Available Since

June 5, 2019

Availability

Academic Institutions and Nonprofits only

Enlarge
pCMV-dCas12a-ABE7

Plasmid

#193644

Purpose

Expression of base editor dCas12a-ABE7 in mammalian cells for base editing, along with non-fused EGFP fluorescence

Depositor

Liangxue Lai

Article

Chen et al Commun Biol. 2022 Nov 2;5(1):1163. doi:

Insert

dLbCas12a-TadA-TadA*7.10, EGFP

Expression

Mammalian

Promoter

CMV

Available Since

Feb. 20, 2024

Availability

Academic Institutions and Nonprofits only

Enlarge
xCas12i

Plasmid

#195333

Purpose

vector for encoding a human codon-optimized xCas12i driven by CBh promoter, guide RNAs compatible with xCas12i driven by hU6, and mCherry driven by CMV promoter

Depositor

Yingsi Zhou

Article

Zhang et al Protein Cell. 2023 Jun 28;14(7):538-543.

Insert

human codon-optimized xCas12i

Tags

3xFlag

Expression

Mammalian

Promoter

CBh, CMV, hU6

Available Since

Jan. 30, 2023

Availability

Academic Institutions and Nonprofits only

Enlarge
AAV-GFAP-NLS-CasRx-NLS-FLAG

Plasmid

#154000

Purpose

Express CasRx for AAV package

Depositor

Hui Yang

Article

Zhou et al Cell. 2020 Apr 30;181(3):590-603.e16. do

Insert

CasRx

Use

AAV and CRISPR

Tags

FLAG

Promoter

GFAP

Available Since

July 16, 2020

Availability

Academic Institutions and Nonprofits only

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pH-Ubi-miniSdd7-nCas9-PBE

Plasmid

#204856

Purpose

For cytosine base editing using miniSdd7 in monocotyledon plants (Agrobacterium-mediated transformation)

Depositor

Caixia Gao

Article

Huang et al Cell. 2023 Jul 20;186(15):3182-3195.e14.

Insert

miniSdd7-nSpCas9(D10A)-UGI

Use

CRISPR

Expression

Plant

Mutation

D10A in SpCas9

Promoter

ZmUbi-1, OsU3, 35S

Available Since

Aug. 17, 2023

Availability

Academic Institutions and Nonprofits only

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pCMV-dCas12a-A3A

Plasmid

#193638

Purpose

Expression of base editor dCas12a-A3A in mammalian cells for base editing, along with non-fused EGFP fluorescence

Depositor

Liangxue Lai

Article

Chen et al Commun Biol. 2022 Nov 2;5(1):1163. doi:

Insert

dLbCas12a-hA3A, EGFP

Expression

Mammalian

Promoter

CMV

Available Since

May 16, 2024

Availability

Academic Institutions and Nonprofits only

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pETDuet-AtRBX1-T7-AtSKP1-T7-AtCUL1-S

Plasmid

#238003

Purpose

Expression AtRBX1-T7, AtSKP1-T7 and AtCUL1-S in in bacterial cells

Depositor

Lei Wu

Article

Pu et al Biomolecules. 2024 Sep 25;14(10):1209. d

Inserts

AtRBX1 (RBX1 Mustard Weed)
AtSKP1 (SKP1 Mustard Weed)
AtCUL1 (CUL1 Mustard Weed)

Tags

S and T7

Expression

Bacterial

Available Since

June 9, 2025

Availability

Academic Institutions and Nonprofits only

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mEGFP-N1-SAV1

Plasmid

#166476

Purpose

Expresses fusion of mEGFP and SAV1

Depositor

Shuguo Sun

Article

Yu et al Mol Cell. 2021 Feb 13. pii: S1097-2765(2

Insert

mEGFP, SAV1 (SAV1 Human)

Expression

Mammalian

Available Since

April 9, 2021

Availability

Academic Institutions and Nonprofits only

Enlarge
pSUMO His6 SUMO PYL1 (36-211)

Plasmid

#177843

Purpose

Bacterial Expression of PYL1

Depositor

Karsten Melcher

Article

Melcher et al Nature. 2009 Dec 3;462(7273):602-8. doi:

Insert

PYR1-like 1 (PYL1 Mustard Weed)

Tags

6xHis-SUMO

Expression

Bacterial

Available Since

Jan. 5, 2022

Availability

Academic Institutions and Nonprofits only

Enlarge
pLVX-M-Flag-BAP1-G185R

Plasmid

#125849

Purpose

express mutant BAP1-G185R

Depositor

Boyi Gan

Article

Zhang et al Nat Cell Biol. 2018 Oct;20(10):1181-1192

Insert

BAP1 (BRCA1 associated protein 1) (BAP1 Human)

Use

Lentiviral

Tags

Flag

Mutation

G185R

Available Since

June 5, 2019

Availability

Academic Institutions and Nonprofits only

Enlarge
pCMV-dCas12a-A3B

Plasmid

#193642

Purpose

Expression of base editor dCas12a-A3B in mammalian cells for base editing, along with non-fused EGFP fluorescence

Depositor

Liangxue Lai

Article

Chen et al Commun Biol. 2022 Nov 2;5(1):1163. doi:

Insert

dLbCas12a-hA3B, EGFP

Expression

Mammalian

Promoter

CMV

Available Since

Feb. 20, 2024

Availability

Academic Institutions and Nonprofits only

Enlarge
pCMV-dCas12a-A3G

Plasmid

#193643

Purpose

Expression of base editor dCas12a-A3G in mammalian cells for base editing, along with non-fused EGFP fluorescence

Depositor

Liangxue Lai

Article

Chen et al Commun Biol. 2022 Nov 2;5(1):1163. doi:

Insert

dLbCas12a-hA3G, EGFP

Expression

Mammalian

Promoter

CMV

Available Since

Feb. 20, 2024

Availability

Academic Institutions and Nonprofits only

Enlarge
pLVX-M-Flag-BAP1-E31A

Plasmid

#125843

Purpose

express mutant BAP1-E31A

Depositor

Boyi Gan

Article

Zhang et al Nat Cell Biol. 2018 Oct;20(10):1181-1192

Insert

BAP1 (BRCA1 associated protein 1) (BAP1 Human)

Use

Lentiviral

Tags

Flag

Mutation

E31A

Available Since

June 5, 2019

Availability

Academic Institutions and Nonprofits only

Enlarge
pLVX-M-Flag-BAP1-S10T

Plasmid

#125842

Purpose

express mutant BAP1-S10T

Depositor

Boyi Gan

Article

Zhang et al Nat Cell Biol. 2018 Oct;20(10):1181-1192

Insert

BAP1 (BRCA1 associated protein 1) (BAP1 Human)

Use

Lentiviral

Tags

Flag

Mutation

S10T

Available Since

June 5, 2019

Availability

Academic Institutions and Nonprofits only

Enlarge
pLVX-M-Flag-BAP1-L49V

Plasmid

#125844

Purpose

express mutant BAP1-L49V

Depositor

Boyi Gan

Article

Zhang et al Nat Cell Biol. 2018 Oct;20(10):1181-1192

Insert

BAP1 (BRCA1 associated protein 1) (BAP1 Human)

Use

Lentiviral

Tags

Flag

Mutation

L49V

Available Since

June 5, 2019

Availability

Academic Institutions and Nonprofits only

Enlarge
pLVX-M-Flag-BAP1-F170C

Plasmid

#125848

Purpose

express mutant BAP1-F170C

Depositor

Boyi Gan

Article

Zhang et al Nat Cell Biol. 2018 Oct;20(10):1181-1192

Insert

BAP1 (BRCA1 associated protein 1) (BAP1 Human)

Use

Lentiviral

Tags

Flag

Mutation

F170C

Available Since

June 5, 2019

Availability

Academic Institutions and Nonprofits only

Enlarge
pLVX-M-Flag-BAP1-G109V

Plasmid

#125846

Purpose

express mutant BAP1-G109V

Depositor

Boyi Gan

Article

Zhang et al Nat Cell Biol. 2018 Oct;20(10):1181-1192

Insert

BAP1 (BRCA1 associated protein 1) (BAP1 Human)

Use

Lentiviral

Tags

Flag

Mutation

G109V

Available Since

June 5, 2019

Availability

Academic Institutions and Nonprofits only

Enlarge
pCHKU38.2-2.2

Plasmid

#110670

Purpose

Expression of a fungal biosynthetic gene cluster

Depositor

Ronald Davis

Article

Harvey et al Sci Adv. 2018 Apr 11;4(4):eaar5459. doi:

Insert

S_cerevisiae_ADH2-ORF1, S_bayanus_ADH2-ORF2, PCK1-ORF3, MLS1-ORF4, S_paradoxus_ADH2-ORF5, S_kudeiaveseii_ADH2-ORF6, ICL1-ORF7

Expression

Yeast

Available Since

June 8, 2018

Availability

Academic Institutions and Nonprofits only

Enlarge
pETDuet-1-AtRBX1-T7-HsSKP1-T7-AtCUL1-S

Plasmid

#228944

Purpose

Expression AtRBX1-T7, HsSKP1-T7 and AtCUL1-S in in bacterial cells

Depositor

Lei Wu

Article

Pu et al Biomolecules. 2024 Sep 25;14(10):1209. d

Inserts

AtRBX1 (RBX1 Mustard Weed)
HsSKP1 (SKP1 Human)
AtCUL1 (CUL1 Mustard Weed)

Tags

S-Tag and T7

Expression

Bacterial

Available Since

March 10, 2026

Availability

Academic Institutions and Nonprofits only

Enlarge
pCMV-sp7(mouse)-3HA

Plasmid

#248782

Purpose

Express mouse sp7 in mammalian cells

Depositor

Wenyan Ren

Article

Wu et al Commun Biol. 2025 Dec 1. doi: 10.1038/s4

Insert

sp7 (Sp7 Mouse)

Tags

3HA

Expression

Mammalian

Promoter

pCMV

Available Since

Jan. 28, 2026

Availability

Academic Institutions and Nonprofits only

Enlarge
pCMV-b-catenin(mouse)-3HA

Plasmid

#248783

Purpose

Express mouse b-catenin in mammalian cells

Depositor

Wenyan Ren

Article

Wu et al Commun Biol. 2025 Dec 1. doi: 10.1038/s4

Insert

b-catenin (Ctnnb1 Mouse)

Tags

3HA

Expression

Mammalian

Promoter

pCMV

Available Since

Jan. 27, 2026

Availability

Academic Institutions and Nonprofits only

Enlarge
DDT Wnt

Plasmid

#248843

Purpose

Double Death Trap (DDT) Wnt reporter Containing FKBP12(F36V)-ΔCaspase9 (FC) and Puromycin Resistance Gene for Assessing Wnt Signaling

Depositor

Hai Jiang

Article

He et al Cell Chem Biol. 2025 Oct 22:S2451-9456(2

Insert

7xTCF binding element

Use

Lentiviral

Promoter

7xTCF binding element & minimal TATA-box prom…

Available Since

Dec. 23, 2025

Availability

Academic Institutions and Nonprofits only

Enlarge
pAAV-EF1α-cOpn5-T2A-mcherry

Plasmid

#237857

Purpose

The transfer plasmid for packaging AAV expressing chicken OPN5 was constructed by inserting the OPN5 coding sequence into the multiple cloning site under the control of a EF1α promoter.

Depositor

Minmin Luo

Article

Dai et al Sci China Life Sci. 2022 Jul;65(7):1271-

Insert

Opn5 (OPN5 Chicken)

Use

AAV

Promoter

EF1α

Available Since

Aug. 25, 2025

Availability

Academic Institutions and Nonprofits only

Enlarge
pAAV-GfaABC1D-cOpn5-T2A-mcherry

Plasmid

#237860

Purpose

The transfer plasmid for packaging AAV expressing chicken OPN5 was constructed by inserting the OPN5 coding sequence into the multiple cloning site under the control of GfaABC1D promoter

Depositor

Minmin Luo

Article

Dai et al Sci China Life Sci. 2022 Jul;65(7):1271-

Insert

Opn5 (OPN5 Chicken)

Use

AAV

Promoter

GfaABC1D

Available Since

Aug. 4, 2025

Availability

Academic Institutions and Nonprofits only

Enlarge
pXPR_023d sgCiPELO #1

Plasmid

#228932

Purpose

Expression of dCas9-KRAB and sgRNA targeting PELO

Depositor

Francisca Vazquez

Article

Borck et al Nature. 2025 Feb 5. doi: 10.1038/s41586-

Insert

PELO gRNA

Use

CRISPR and Lentiviral

Expression

Mammalian

Available Since

April 3, 2025

Availability

Academic Institutions and Nonprofits only

Enlarge
pRDA355_sgCiCh2-2

Plasmid

#229021

Purpose

Expression of a CRISPRi doxycycline inducible control sgRNA that cuts an intergenic region on chromosome 2

Depositor

Francisca Vazquez

Article

Borck et al Nature. 2025 Feb 5. doi: 10.1038/s41586-

Insert

sgChr2-2

Use

CRISPR and Lentiviral

Expression

Mammalian

Available Since

April 3, 2025

Availability

Academic Institutions and Nonprofits only

Enlarge
pXPR_023d sgCiPELO #8

Plasmid

#228934

Purpose

Expression of dCas9-KRAB and sgRNA targeting PELO

Depositor

Francisca Vazquez

Article

Borck et al Nature. 2025 Feb 5. doi: 10.1038/s41586-

Insert

PELO gRNA

Use

CRISPR and Lentiviral

Expression

Mammalian

Available Since

April 3, 2025

Availability

Academic Institutions and Nonprofits only

Enlarge
pXPR_051d_sgCiChr2-2

Plasmid

#228940

Purpose

Expression of a CRISPRi control sgRNA that cuts an intergenic region on chromosome 2

Depositor

Francisca Vazquez

Article

Borck et al Nature. 2025 Feb 5. doi: 10.1038/s41586-

Insert

sgChr2-2

Use

CRISPR and Lentiviral

Expression

Mammalian

Available Since

April 3, 2025

Availability

Academic Institutions and Nonprofits only

Enlarge
U6-sgRNA-hcr3

Plasmid

#193660

Purpose

Expression of tandem pre-sgRNA array hcr3 for LbCas12a

Depositor

Liangxue Lai

Article

Chen et al Commun Biol. 2022 Nov 2;5(1):1163. doi:

Insert

U6-CFTR-sgRNA-KLF4-sgRNA-TET1-sgRNA-tRNA

Expression

Mammalian

Promoter

U6

Available Since

Feb. 20, 2024

Availability

Academic Institutions and Nonprofits only

Enlarge
U6-sgRNA-hcr5

Plasmid

#193661

Purpose

Expression of tandem pre-sgRNA array hcr5 for LbCas12a

Depositor

Liangxue Lai

Article

Chen et al Commun Biol. 2022 Nov 2;5(1):1163. doi:

Insert

U6-DNMT3B-sgRNA-KLF4-sgRNA-TET1-sgRNA-PRR5L-sgRNA-CFTR-sgRNA-tRNA

Expression

Mammalian

Promoter

U6

Available Since

Feb. 20, 2024

Availability

Academic Institutions and Nonprofits only

Enlarge
U6-sgRNA-pcr4

Plasmid

#193662

Purpose

Expression of tandem pre-sgRNA array pcr4 for LbCas12a

Depositor

Liangxue Lai

Article

Chen et al Commun Biol. 2022 Nov 2;5(1):1163. doi:

Insert

U6-PUM1-sgRNA-GHR-sgRNA-HMGA2-sgRNA-PUM2-sgRNA-tRNA

Expression

Mammalian

Promoter

U6

Available Since

Feb. 20, 2024

Availability

Academic Institutions and Nonprofits only

Enlarge
pCMV-dCas12a-AID

Plasmid

#193647

Purpose

Expression of base editor dCas12a-AID in mammalian cells for base editing, along with non-fused EGFP fluorescence

Depositor

Liangxue Lai

Article

Chen et al Commun Biol. 2022 Nov 2;5(1):1163. doi:

Insert

dLbCas12a-hAID, EGFP

Expression

Mammalian

Promoter

CMV

Available Since

Feb. 20, 2024

Availability

Academic Institutions and Nonprofits only

Enlarge

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