Addgene

We narrowed to 41,024 results for: TRO

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HR700_TP53Exon5mut

Pooled Library

#229137

Purpose

Donor vector library to introduce TP53 mutations into the endogenous gene locus at exon 5 of human cells via CRISPR-HDR.

Depositor

Thorsten Stiewe

Article

Funk et al Nat Genet. 2025 Jan;57(1):140-153. doi:

Expression

Mammalian

Species

Homo sapiens

Use

CRISPR and Cre/Lox

Available since

Feb. 24, 2025

Availability

Industry, Academic Institutions, and Nonprofits
HR700_TP53Exon6mut

Pooled Library

#229138

Purpose

Donor vector library to introduce TP53 mutations into the endogenous gene locus at exon 6 of human cells via CRISPR-HDR.

Depositor

Thorsten Stiewe

Article

Funk et al Nat Genet. 2025 Jan;57(1):140-153. doi:

Expression

Mammalian

Species

Homo sapiens

Use

CRISPR and Cre/Lox

Available since

Feb. 24, 2025

Availability

Industry, Academic Institutions, and Nonprofits
HR700_TP53Exon7mut

Pooled Library

#229139

Purpose

Donor vector library to introduce TP53 mutations into the endogenous gene locus at exon 7 of human cells via CRISPR-HDR.

Depositor

Thorsten Stiewe

Article

Funk et al Nat Genet. 2025 Jan;57(1):140-153. doi:

Expression

Mammalian

Species

Homo sapiens

Use

CRISPR and Cre/Lox

Available since

Feb. 24, 2025

Availability

Industry, Academic Institutions, and Nonprofits
HR700_TP53Exon8mut

Pooled Library

#229140

Purpose

Donor vector library to introduce TP53 mutations into the endogenous gene locus at exon 8 of human cells via CRISPR-HDR.

Depositor

Thorsten Stiewe

Article

Funk et al Nat Genet. 2025 Jan;57(1):140-153. doi:

Expression

Mammalian

Species

Homo sapiens

Use

CRISPR and Cre/Lox

Available since

Feb. 24, 2025

Availability

Industry, Academic Institutions, and Nonprofits
plIG-106_NY-ESO-1_TCR_SR_Library

Pooled Library

#207474

Purpose

NY-ESO-1 TCR in combination with 129 surface receptors and 2 controls (GFP/RFP). Library can be used to generate HDR templates for modular pooled knockin (ModPoKI) into the TRAC locus of human T cells

Depositor

Alexander Marson

Article

Blaeschke et al Cell. 2023 Sep 14;186(19):4216-4234.e33.

Species

Homo sapiens

Use

CRISPR

Available since

Jan. 26, 2024

Availability

Academic Institutions and Nonprofits only
plIG-107_NY-ESO-1_TCR_TF_Library

Pooled Library

#207475

Purpose

NY-ESO-1 TCR in combination with 100 transcription factors (and related proteins) and 2 controls (GFP/RFP). Library can be used to generate HDR templates for modular pooled knockin (ModPoKI) into the

Depositor

Alexander Marson

Article

Blaeschke et al Cell. 2023 Sep 14;186(19):4216-4234.e33.

Species

Homo sapiens

Use

CRISPR

Available since

Jan. 26, 2024

Availability

Academic Institutions and Nonprofits only
plIG-109_CD19-BBz_CAR_SR_Library

Pooled Library

#207476

Purpose

CD19-BBz CAR in combination with 129 surface receptors and 2 controls (GFP/RFP). Library can be used to generate HDR templates for modular pooled knockin (ModPoKI) into the TRAC locus of human T cells

Depositor

Alexander Marson

Article

Blaeschke et al Cell. 2023 Sep 14;186(19):4216-4234.e33.

Use

CRISPR

Available since

Jan. 26, 2024

Availability

Academic Institutions and Nonprofits only
plIG-110_CD19-BBz_CAR_TF_Library

Pooled Library

#207477

Purpose

CD19-BBz CAR in combination with 100 transcription factors (and related proteins) and 2 controls (GFP/RFP). Library can be used to generate HDR templates for modular pooled knockin (ModPoKI) into the

Depositor

Alexander Marson

Article

Blaeschke et al Cell. 2023 Sep 14;186(19):4216-4234.e33.

Species

Homo sapiens

Use

CRISPR

Available since

Jan. 26, 2024

Availability

Academic Institutions and Nonprofits only
plIG-124_HA-GD2-28z_CAR_SR_Library

Pooled Library

#207479

Purpose

HA-GD2-28z CAR in combination with 129 surface receptors and 2 controls (GFP/RFP). Library can be used to generate HDR templates for modular pooled knockin (ModPoKI) into the TRAC locus of human T cel

Depositor

Alexander Marson

Article

Blaeschke et al Cell. 2023 Sep 14;186(19):4216-4234.e33.

Species

Homo sapiens

Use

CRISPR

Available since

Jan. 26, 2024

Availability

Academic Institutions and Nonprofits only
plIG-132_CD19-28z_CAR_TF_and_SR_Library

Pooled Library

#207481

Purpose

CD19-28z CAR in combination with 129 surface receptors, 100 transcription factors (and related proteins) and 2 controls (GFP/RFP). Library can be used to generate HDR templates for modular pooled knoc

Depositor

Alexander Marson

Article

Blaeschke et al Cell. 2023 Sep 14;186(19):4216-4234.e33.

Species

Homo sapiens

Use

CRISPR

Available since

Jan. 26, 2024

Availability

Academic Institutions and Nonprofits only
Cultivarium POSSUM Toolkit

Plasmid Kit

#1000000234

Purpose

The POSSUM Toolkit is a Golden Gate genetic toolkit developed to help researchers identify functional plasmids and establish genetic tractability in non-model microbes.

Depositor

Nili Ostrov

Available since

Feb. 23, 2024

Availability

Academic Institutions and Nonprofits only
Target Accelerator Lung Cancer Mutant Collection

Plasmid Kit

#1000000104

Purpose

Panel of lung adenocarcinoma alleles that have undergone basic, functional screening; full-length human clones (180 mutant and 45 corresponding wild-type) and 82 wild-type experssion controls

Depositor

Jesse Boehm

Available since

April 24, 2017

Availability

Academic Institutions and Nonprofits only
3X ERE TATA luc

Plasmid

#11354

Purpose

Luciferase reporter containing three copies of vitellogenin Estrogen Response Element

Depositor

Donald McDonnell

Article

Hall et al Endocrinology. 1999 Dec . 140(12):5566-7

Insert

ERE

Use

Luciferase

Tags

Expression

Bacterial

Mutation

Promoter

Available since

April 20, 2006

Availability

Academic Institutions and Nonprofits only

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pRST7-ER beta (long)

Plasmid

#11356

Depositor

Donald McDonnell

Article

Hall et al Endocrinology. 1999 Dec . 140(12):5566-7

Insert

ER beta long (ESR2 Human)

Use

Tags

Expression

Mammalian

Mutation

Promoter

Available since

March 10, 2006

Availability

Academic Institutions and Nonprofits only
pRST7-ER beta (short)

Plasmid

#11357

Depositor

Donald McDonnell

Article

Hall et al Endocrinology. 1999 Dec . 140(12):5566-7

Insert

ER beta short (ESR2 Human)

Use

Tags

Expression

Mammalian

Mutation

Promoter

Available since

March 10, 2006

Availability

Academic Institutions and Nonprofits only
inhibin-DsRed

Plasmid

#156184

Purpose

Expression plasmid for production of transgenic rainbow trout strain carrying the DsRed gene under control of the inhibin α promoter.

Depositor

Goro Yoshizaki

Article

Iwasaki-Takahashi et al Commun Biol. 2020 Jun 15;3(1):308. doi:

Inserts

rainbow trout inhibin α promoter
rainbow trout β actin 3'UTR

Use

Tags

Expression

Bacterial

Mutation

Promoter

inhibin

Available since

Aug. 21, 2020

Availability

Academic Institutions and Nonprofits only

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pENTR4 CDS A. thaliana PHOT1

Plasmid

#209187

Purpose

pENTR4 plasmid with CDS of Arabidopsis thaliana PHOTOTROPIN 1 (PHOT1, AT3G45780.1) without stop codon for C-terminal epitope tags

Depositor

Lennart Wirthmueller

Article

Simranjit et al bioRxiv 2023.09.25.558804

Insert

AT3G45780.1 (PHOT1 Mustard Weed)

Use

Gateway-compatible entry vector

Tags

Expression

Mutation

Promoter

none

Available since

Nov. 21, 2023

Availability

Academic Institutions and Nonprofits only

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pLXRN

Plasmid

#99206

Purpose

Bicistronic retroviral vector

Depositor

Peter Pedersen

Type

Empty backbone

Use

Retroviral

Tags

Expression

Mammalian

Mutation

Promoter

LTR

Available since

Aug. 18, 2017

Availability

Academic Institutions and Nonprofits only

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pCMV-hERalpha

Plasmid

#101141

Purpose

Mammalian expression of full-length human estrogen receptor-alpha

Depositor

Elizabeth Wilson

Article

Mao et al J Biol Chem. 2008 May 9;283(19):12819-30

Insert

estrogen receptor-alpha (ESR1 Human)

Use

Tags

Expression

Mammalian

Mutation

Promoter

CMV

Available since

Sept. 6, 2017

Availability

Academic Institutions and Nonprofits only

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pLXRN-EGFP

Plasmid

#99207

Purpose

EGFP expressing bicistronic retroviral vector

Depositor

Peter Pedersen

Insert

EGFP

Use

Retroviral

Tags

Expression

Mammalian

Mutation

A Kozak sequence was incorporated to enhance tran…

Promoter

LTR

Available since

Aug. 18, 2017

Availability

Academic Institutions and Nonprofits only

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