We narrowed to 18,516 results for: MUT

1. N-terminal 3X Flag Human CASP9 C287A Mutant

   Plasmid

   #198380

   Purpose

   Expresses Human N-Terminal 3X Flag CASP9 Catalytic Mutant in Mammalian Cells

   Depositor

   Hannah Rabinowich

   Article

   Han et al Autophagy. 2021 Jun;17(6):1393-1409. doi

   Insert

   N-Terminal 3X Flag Human Caspase-9 C287A Mutant (CASP9 Human)
   

   Tags

   3X Flag

   Expression

   Mammalian

   Mutation

   Changed Cysteine 287 to Alanine to eliminate prot…

   Promoter

   CMV

   Available Since

   April 14, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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2. pmiRGLO Dual-Luciferase-PDAP1-3'UTR-Mut4x

   Plasmid

   #182256

   Purpose

   Human PDAP1 3` UTR region mutated in 4x binding site for miR-150 cloned downstream of luciferase reporter gene

   Depositor

   Silvia Monticelli

   Article

   Chirichella et al PLoS Biol. 2022 Feb 10;20(2):e3001538. d

   Insert

   3' UTR region of PDAP1 gene mutated in 4 binding sites for mir-150
   

   Use

   Luciferase

   Expression

   Mammalian

   Available Since

   April 22, 2022

   Availability

   Academic Institutions and Nonprofits only

   

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3. pAAV-EF1α-F-FLEX-mNaChBacMut-T2A-tdTomato

   Plasmid

   #60660

   Purpose

   Flp-dependent expression of mNaChBacMut-T2A-tdTomato

   Depositor

   Massimo Scanziani

   Article

   Xue et al Nature. 2014 Jul 31;511(7511):596-600. d

   Insert

   FLEX-mNaChBacMut-T2A-tdTomato
   

   Use

   AAV

   Mutation

   E191K

   Promoter

   EF1α

   Available Since

   Oct. 31, 2014

   Availability

   Academic Institutions and Nonprofits only

   

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4. pAAV-EF1a-DIO-mGFP-MutCREB(S133A)

   Plasmid

   #194642

   Purpose

   Expresses the fusion of monomeric-EGFP-tagged mutant CREB(S133A) in a Cre-dependent manner

   Depositor

   Jun-Hyeong Cho

   Article

   Lee et al Nat Neurosci. 2022 Dec 23. doi: 10.1038/

   Insert

   CREB (Creb1 Rat)
   

   Use

   AAV

   Tags

   mEGFP

   Mutation

   S133A

   Available Since

   Jan. 10, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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5. MG15-luc (mut p53 binding sites)

   Plasmid

   #16443

   Depositor

   Bert Vogelstein

   Article

   el-Deiry et al Cell. 1993 Nov 19. 75(4):817-25.

   Insert

   p53-binding site (mutant) (TP53 )
   

   Use

   Luciferase

   Tags

   luciferase

   Expression

   Mammalian

   Available Since

   March 12, 2008

   Availability

   Academic Institutions and Nonprofits only

   

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6. p53 (dominant negative R175H mutant)-pcw107-V5

   Plasmid

   #64638

   Purpose

   3rd generation lentiviral transfer plasmid. When used to produce lentivirus, express physiological levels of insert

   Depositor

   Kris Wood, David Sabatini

   Article

   Martz et al Sci Signal. 2014 Dec 23;7(357):ra121. do

   Insert

   TP53 (transcript variant 3) (TP53 Human)
   

   Use

   Lentiviral

   Tags

   V5

   Mutation

   R175H

   Promoter

   PGK

   Available Since

   Dec. 1, 2015

   Availability

   Academic Institutions and Nonprofits only

   

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7. p2xFlag CMV2-YAP2-1st&2nd WW mutant

   Plasmid

   #19048

   Depositor

   Marius Sudol

   Article

   Oka et al J Biol Chem. 2008 Oct 10;283(41):27534-2

   Insert

   Yes-kinase associated protein (YAP1 Human)
   

   Tags

   2xFlag

   Expression

   Mammalian

   Mutation

   Tryptophan 199 changed to Alanine,and Proline 202…

   Available Since

   Sept. 8, 2008

   Availability

   Academic Institutions and Nonprofits only

   

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8. pCDH-3_Flag-YTHDF2 (nonsense mutation of sgYTHDF2-1)

   Plasmid

   #232945

   Purpose

   Expresses YTHDF2 with synonymous mutations rendering it resistant to sgYTHDF2-1-mediated knockdown

   Depositor

   Jianjun Chen

   Article

   Chen et al Cell. 2024 Dec 12:S0092-8674(24)01324-2.

   Insert

   YTHDF2 (YTHDF2 Human)
   

   Use

   Lentiviral

   Mutation

   synonymous mutation

   Available Since

   May 16, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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9. pBabe-GFP-IKBalpha-mut (super repressor)

   Plasmid

   #15264

   Depositor

   William Hahn

   Article

   Boehm et al Cell. 2007 Jun 15. 129(6):1065-1079.

   Insert

   IKB alpha (NFKBIA Human)
   

   Use

   Retroviral

   Expression

   Mammalian

   Mutation

   Serine 32 to Alanine, Serine 36 to Alanine

   Available Since

   July 12, 2007

   Availability

   Academic Institutions and Nonprofits only

   

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10. EK0208 CMV-TO-BFPmut-stop-t70587 (FLP-IN)

    Plasmid

    #191138

    Purpose

    Expression of Trigger 1 in 3' UTR of an inactive BFP in mammalian cells

    Depositor

    Xiaojing Gao

    Article

    Kaseniit et al Nat Biotechnol. 2022 Oct 5. pii: 10.1038

    Insert

    t70587
    

    Expression

    Mammalian

    Mutation

    WT

    Promoter

    CMV-TO

    Available Since

    Oct. 26, 2022

    Availability

    Academic Institutions and Nonprofits only

    

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11. pUC19-HDRT-TRAC-CD19.CAR-Cas12a.PAM.mutated

    Plasmid

    #215769

    Purpose

    encodes for HDR template for optimized AsCas12a-mediated knock-in of a CD19-specific CAR into the TRAC locus

    Depositor

    Dimitrios Wagner

    Article

    Glaser et al Genome Biol. 2023 Apr 24;24(1):89. doi:

    Inserts

    TRAC-5' homology arm (TRAC Human)
    P2A-CD19.28.zeta-bgH (CD19 Bovine, Human, Mouse)
    TRAC-3' homology arm (TRAC Human)
    

    Expression

    Bacterial

    Mutation

    Cas12a PAM mutated

    Available Since

    June 5, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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12. EK0304 CMV-TO-BFPmut-stop-Bdnf.t1 (FLP-IN)

    Plasmid

    #191146

    Purpose

    Expression of only the trigger sequence for Bdnf.s1 (EK0301) in mammalian cells

    Depositor

    Xiaojing Gao

    Article

    Kaseniit et al Nat Biotechnol. 2022 Oct 5. pii: 10.1038

    Insert

    Bdnf.t1
    

    Expression

    Mammalian

    Mutation

    WT

    Promoter

    CMV-TO

    Available Since

    Oct. 26, 2022

    Availability

    Academic Institutions and Nonprofits only

    

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13. Flag- MCL1-3A (S159, S162, T163 mutated to A)

    Plasmid

    #197458

    Purpose

    MCL-1 phosphodegron mutants

    Depositor

    Omar Khan

    Article

    Keyan et al Cancers (Basel). 2023 Jan 13;15(2):505.

    Insert

    MCL1 (MCL1 Human)
    

    Tags

    Flag

    Expression

    Mammalian

    Mutation

    S159A, S161A, T163A

    Promoter

    CMV

    Available Since

    Aug. 1, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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14. pLenti HRE mutant-Luc pGK Hygro

    Plasmid

    #118707

    Purpose

    reporter plasmid, HIF-responsive promoter (3xHRE) mutant- fused to firefly luciferase

    Depositor

    William Kaelin

    Article

    Briggs et al Cell. 2016 Jun 30;166(1):126-39. doi: 10

    Insert

    HREmutant-Luc
    

    Use

    Lentiviral

    Available Since

    Nov. 26, 2018

    Availability

    Academic Institutions and Nonprofits only

    

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15. DENV4 Rluc Reporter GND mutant Replicon

    Plasmid

    #118586

    Purpose

    For use as a positive control for translation of the Rluc gene in the transfected cells and negative control for replication.

    Depositor

    Radhakrishnan Padmanabhan

    Article

    Alcaraz-Estrada et al J Gen Virol. 2010 Nov;91(Pt 11):2713-8.

    Insert

    DENV4 Renilla luciferase gene (Rluc) reporter replicon containing replication-defective GND mutation in the NS5 polymerase gene.
    

    Use

    Yeast-e. col shuttle vector prs424

    Mutation

    The conserved GDD in the NS5 polymerase gene muta…

    Available Since

    Aug. 2, 2021

    Availability

    Academic Institutions and Nonprofits only

    

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16. pDisplay-GRAB-HaloDAmut-IRES-EGFP-CAAX

    Plasmid

    #234411

    Purpose

    Expresses the chemigenetic dopamine (DA) control sensor GRAB_HaloDAmut and a membrane-localized EGFP in mammalian cells

    Depositor

    Yulong Li

    Article

    Zheng et al Science. 2025 Jun 5;388: 6751. doi: http

    Insert

    GPCR activation based chemigenetic dopamine (DA) control sensor GRAB_HaloDAmut
    

    Expression

    Mammalian

    Promoter

    CMV

    Available Since

    June 2, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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17. pAAV-hSyn-FLAG-HA-T6B-MUT-YFP

    Plasmid

    #235140

    Purpose

    Expresses the mutant T6B peptide fused with YFP under the human synapsin promoter

    Depositor

    Giordano Lippi

    Article

    Zolboot et al Neuron. 2025 Apr 1:S0896-6273(25)00181-3

    Insert

    mutant T6B peptide
    

    Use

    AAV

    Tags

    FLAG/HA

    Mutation

    5 tryptophan residues of T6B-WT mutated

    Promoter

    hSyn

    Available Since

    April 23, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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18. pCS2 stabilized mutant Beta Catenin-GFP

    Plasmid

    #29684

    Depositor

    Edward De Robertis

    Article

    Taelman et al Cell. 2010 Dec 23. 143(7):1136-48.

    Insert

    beta catenin (ctnnb1.L Frog)
    

    Tags

    GFP

    Expression

    Mammalian

    Mutation

    S33A, S37A, T41A

    Available Since

    Oct. 5, 2011

    Availability

    Academic Institutions and Nonprofits only

19. pSB-CMV-MCS-Puro GEM-LTB4mut

    Plasmid

    #202642

    Purpose

    Expresses the LTB4-insensitive control sensor GEM-LTB4mut in mammalian cells

    Depositor

    Balázs Enyedi

    Article

    Tamas et al Nat Commun. 2023 Aug 1;14(1):4610. doi:

    Insert

    GEM-LTB4mut
    

    Expression

    Mammalian

    Promoter

    CMV

    Available Since

    Aug. 8, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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20. EK0211 CMV-TO-BFPmut-stop-t17d9b (FLP-IN)

    Plasmid

    #191139

    Purpose

    Expression of Trigger 2 in 3' UTR of an inactive BFP in mammalian cells. Used as second input in OR, AND gates

    Depositor

    Xiaojing Gao

    Article

    Kaseniit et al Nat Biotechnol. 2022 Oct 5. pii: 10.1038

    Insert

    t17d9b
    

    Expression

    Mammalian

    Mutation

    WT

    Promoter

    CMV-TO

    Available Since

    Oct. 26, 2022

    Availability

    Academic Institutions and Nonprofits only

    

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