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We narrowed to 10,187 results for: gnas

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Showing: 101 - 120 of 10187 results

  1. G protein alpha-s(alpha3beta5/G226A/A366S)

    Plasmid
    #55797
    Purpose
    This highly effective dominant negative G protein alpha-s mutant contains, in addition to the mutations in alpha-s(alpha3beta5/G226A), the A366S mutation, which increases GDP release.
    Depositor
    Catherine Berlot
    Article
    Berlot et al J Biol Chem. 2002 Jun 7;277(23):21080-5.
    Insert
    alpha-s (alpha3beta5/G226A/A366S) (Gnas Rat)
    Tags
    internal EE epitope (residues 189-194 in alpha-s …
    Expression
    Mammalian
    Mutation
    N271K, K274D, R280K, T284D, I285T, G226A, A366S i…
    Promoter
    CMV
    Available Since
    Aug. 4, 2015
    Availability
    Academic Institutions and Nonprofits only
    55797-plasmid-map-sequence-id-112181

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  4. G protein alpha-s(alpha3beta5)

    Plasmid
    #55799
    Purpose
    This G protein alpha-s mutant exhibits increased affinity for and decreased ability to be activated by Gs-protein-coupled receptors as well as decreased ability to activate adenylyl cyclase.
    Depositor
    Catherine Berlot
    Article
    Berlot et al J Biol Chem. 2002 Jun 7;277(23):21080-5.
    Insert
    G protein alpha-s with alpha-i2 substitutions in alpha3/beta5 loop (Gnas Rat)
    Tags
    internal EE epitope (residues 189-194 in alpha-s …
    Expression
    Mammalian
    Mutation
    N271K, K274D, R280K, T284D, I285T in alpha-s sequ…
    Promoter
    CMV
    Available Since
    July 23, 2015
    Availability
    Academic Institutions and Nonprofits only
    55799-plasmid-map-sequence-id-119340

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  5. G protein alpha-s(alpha3beta5/G226A)

    Plasmid
    #55798
    Purpose
    In addition to the mutations in alpha-s(alpha3beta5), this dominant negative G protein alpha-s mutant contains the G226A mutation, which impairs activating conformation changes in Switch II.
    Depositor
    Catherine Berlot
    Article
    Berlot et al J Biol Chem. 2002 Jun 7;277(23):21080-5.
    Insert
    alpha-s (alpha3beta5/G226A) (Gnas Rat)
    Tags
    internal EE epitope (residues 189-194 in alpha-s …
    Expression
    Mammalian
    Mutation
    N271K, K274D, R280K, T284D, I285T, G226A in alpha…
    Promoter
    CMV
    Available Since
    Aug. 4, 2015
    Availability
    Academic Institutions and Nonprofits only
    55798-plasmid-map-sequence-id-112177

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  7. pZac2.1 gfaABC1D-cyto-GCaMP6f (AAV5)

    Viral Prep
    #52925-AAV5
    Purpose
    Ready-to-use AAV5 particles produced from pZac2.1 gfaABC1D-cyto-GCaMP6f (#52925). In addition to the viral particles, you will also receive purified pZac2.1 gfaABC1D-cyto-GCaMP6f plasmid DNA. gfaABC1D-driven (similar to GFAP promoter) cyto-GCaMP6f calcium sensor expression. These AAV preparations are suitable purity for injection into animals.
    Depositor
    Baljit Khakh
    Article
    Haustein et al Neuron. 2014 Apr 16;82(2):413-29. doi: 1
    Available Since
    April 5, 2018
    Availability
    Academic Institutions and Nonprofits only

  8. pAAV-CaMKIIa-hChR2(H134R)-EYFP (AAV5)

    Viral Prep
    #26969-AAV5
    Purpose
    Ready-to-use AAV5 particles produced from pAAV-CaMKIIa-hChR2(H134R)-EYFP (#26969). In addition to the viral particles, you will also receive purified pAAV-CaMKIIa-hChR2(H134R)-EYFP plasmid DNA. CaMKIIa-driven, humanized channelrhodopsin H134R mutant fused to EYFP for optogenetic activation. These AAV preparations are suitable purity for injection into animals.
    Depositor
    Karl Deisseroth
    Article
    Lee et al Nature. 2010 Jun 10. 465(7299):788-92.
    Promoter
    CaMKII
    Tags
    EYFP
    Available Since
    March 7, 2018
    Availability
    Academic Institutions and Nonprofits only

  9. pZac2.1-GfaABC1D-mCherry-hPMCA2w/b (AAV5)

    Viral Prep
    #111568-AAV5
    Purpose
    Ready-to-use AAV5 particles produced from pZac2.1-GfaABC1D-mCherry-hPMCA2w/b (#111568). In addition to the viral particles, you will also receive purified pZac2.1-GfaABC1D-mCherry-hPMCA2w/b plasmid DNA. GfaABCD1-driven, expression of mCherry fused plasma membrane calcium pump hPMCA2w/b. These AAV preparations are suitable purity for injection into animals.
    Depositor
    Baljit Khakh
    Article
    Yu et al Neuron. 2018 Aug 27. pii: S0896-6273(18)
    Tags
    mCherry
    Available Since
    Feb. 14, 2022
    Availability
    Academic Institutions and Nonprofits only

  10. pAAV-CaMKIIa-hChR2(H134R)-EYFP (AAV9)

    Viral Prep
    #26969-AAV9
    Purpose
    Ready-to-use AAV9 particles produced from pAAV-CaMKIIa-hChR2(H134R)-EYFP (#26969). In addition to the viral particles, you will also receive purified pAAV-CaMKIIa-hChR2(H134R)-EYFP plasmid DNA. CaMKIIa-driven, humanized channelrhodopsin H134R mutant fused to EYFP for optogenetic activation. These AAV preparations are suitable purity for injection into animals.
    Depositor
    Karl Deisseroth
    Article
    Lee et al Nature. 2010 Jun 10. 465(7299):788-92.
    Promoter
    CaMKII
    Tags
    EYFP
    Available Since
    March 7, 2018
    Availability
    Academic Institutions and Nonprofits only

  11. pAAV/D377Y-mPCSK9 (AAV8)

    Viral Prep
    #58376-AAV8
    Purpose
    Ready-to-use AAV8 particles produced from pAAV/D377Y-mPCSK9 (#58376). In addition to the viral particles, you will also receive purified pAAV/D377Y-mPCSK9 plasmid DNA. hAAT-driven expression of mutant (D377Y) murine PCSK9. These AAV preparations are suitable purity for injection into animals.
    Depositor
    Jacob Bentzon
    Article
    Bjorklund et al Circ Res. 2014 May 23;114(11):1684-9. do
    Promoter
    HCRApoE/hAAT
    Available Since
    July 30, 2025
    Availability
    Academic Institutions and Nonprofits only

  12. pAAV-CaMKIIa-hChR2(H134R)-EYFP (AAV1)

    Viral Prep
    #26969-AAV1
    Purpose
    Ready-to-use AAV1 particles produced from pAAV-CaMKIIa-hChR2(H134R)-EYFP (#26969). In addition to the viral particles, you will also receive purified pAAV-CaMKIIa-hChR2(H134R)-EYFP plasmid DNA. CaMKIIa-driven, humanized channelrhodopsin H134R mutant fused to EYFP for optogenetic activation. These AAV preparations are suitable purity for injection into animals.
    Depositor
    Karl Deisseroth
    Article
    Lee et al Nature. 2010 Jun 10. 465(7299):788-92.
    Promoter
    CaMKII
    Tags
    EYFP
    Available Since
    May 9, 2018
    Availability
    Academic Institutions and Nonprofits only

  13. pAAV.cTNT.iCre (AAV9)

    Viral Prep
    #69916-AAV9
    Purpose
    Ready-to-use AAV9 particles produced from pAAV.cTNT.iCre (#69916). In addition to the viral particles, you will also receive purified pAAV.cTNT.iCre plasmid DNA. cTnT driven in vivo expression of Cre and tdTomato (separated by IRES sequence). These AAV preparations are suitable purity for injection into animals.
    Depositor
    William Pu
    Article
    Lin et al Circ Res. 2015 Jan 2;116(1):35-45. doi:
    Promoter
    Chicken cardiac troponin T
    Tags
    tdTomato
    Available Since
    July 31, 2025
    Availability
    Academic Institutions and Nonprofits only

  14. pAAV-CaMKIIa-hChR2(H134R)-EYFP (AAV2)

    Viral Prep
    #26969-AAV2
    Purpose
    Ready-to-use AAV2 particles produced from pAAV-CaMKIIa-hChR2(H134R)-EYFP (#26969). In addition to the viral particles, you will also receive purified pAAV-CaMKIIa-hChR2(H134R)-EYFP plasmid DNA. CaMKIIa-driven, humanized channelrhodopsin H134R mutant fused to EYFP for optogenetic activation. These AAV preparations are suitable purity for injection into animals.
    Depositor
    Karl Deisseroth
    Article
    Lee et al Nature. 2010 Jun 10. 465(7299):788-92.
    Promoter
    CaMKII
    Tags
    EYFP
    Available Since
    Feb. 14, 2018
    Availability
    Academic Institutions and Nonprofits only

  15. pAAV/D374Y-hPCSK9 (AAV8)

    Viral Prep
    #58379-AAV8
    Purpose
    Ready-to-use AAV8 particles produced from pAAV/D374Y-hPCSK9 (#58379). In addition to the viral particles, you will also receive purified pAAV/D374Y-hPCSK9 plasmid DNA. hAAT-driven expression of mutant (D374Y) human PCSK9. These AAV preparations are suitable purity for injection into animals.
    Depositor
    Jacob Bentzon
    Article
    Bjorklund et al Circ Res. 2014 May 23;114(11):1684-9. do
    Promoter
    HCRApoE/hAAT
    Available Since
    Feb. 6, 2026
    Availability
    Academic Institutions and Nonprofits only

  16. pAAV hSyn-fDIO-taCasp3-TEVp (AAV5)

    Viral Prep
    #207997-AAV5
    Purpose
    Ready-to-use AAV5 particles produced from pAAV hSyn-fDIO-taCasp3-TEVp (#207997). In addition to the viral particles, you will also receive purified pAAV hSyn-fDIO-taCasp3-TEVp plasmid DNA. hSyn-driven, Flp-dependent, expression of taCasp3-TEVp. These AAV preparations are suitable purity for injection into animals.
    Depositor
    Kazunari Miyamichi
    Article
    Goto et al Neuron. 2025 Feb 17:S0896-6273(25)00041-
    Promoter
    hSyn promoter
    Available Since
    Nov. 13, 2025
    Availability
    Academic Institutions and Nonprofits only

  17. pAAV-synP-FLEX-splitTVA-EGFP-B19G (AAV1)

    Viral Prep
    #52473-AAV1
    Purpose
    Ready-to-use AAV1 particles produced from pAAV-synP-FLEX-splitTVA-EGFP-B19G (#52473). In addition to the viral particles, you will also receive purified pAAV-synP-FLEX-splitTVA-EGFP-B19G plasmid DNA. Helper virus for monosynaptic tracing with rabies virus. These AAV preparations are suitable purity for injection into animals.
    Depositor
    Ian Wickersham
    Article
    Kohara et al Nat Neurosci. 2014 Feb;17(2):269-79. doi
    Promoter
    Syn
    Tags
    EGFP (Cre-dependent)
    Available Since
    Dec. 18, 2018
    Availability
    Academic Institutions and Nonprofits only

  18. pAAV-DIO-EF1α-mKate2-PDE4D3-Cat (AAV1)

    Viral Prep
    #169128-AAV1
    Purpose
    Ready-to-use AAV1 particles produced from pAAV-DIO-EF1α-mKate2-PDE4D3-Cat (#169128). In addition to the viral particles, you will also receive purified pAAV-DIO-EF1α-mKate2-PDE4D3-Cat plasmid DNA. EF1a-driven, Cre-dependent expression of truncated PDE4D3 and mKate2. These AAV preparations are suitable purity for injection into animals.
    Depositor
    Georg Nagel
    Article
    Zhang et al Nature. 2021 Sep;597(7875):245-249. doi:
    Promoter
    EF1a
    Available Since
    Aug. 7, 2025
    Availability
    Academic Institutions and Nonprofits only

  19. pAAV-hSyn-fDIO-hM4D(Gi)-mCherry-WPREpA (AAV8)

    Viral Prep
    #154867-AAV8
    Purpose
    Ready-to-use AAV8 particles produced from pAAV-hSyn-fDIO-hM4D(Gi)-mCherry-WPREpA (#154867). In addition to the viral particles, you will also receive purified pAAV-hSyn-fDIO-hM4D(Gi)-mCherry-WPREpA plasmid DNA. Syn-driven, Flp-dependent hM4D(Gi) receptor with an mCherry reporter for CNO-induced neuronal inhibition. These AAV preparations are suitable purity for injection into animals.
    Depositor
    Ulrik Gether
    Article
    Runegaard et al eNeuro. 2018 Jun 18;5(3). pii: eN-NWR-03
    Promoter
    Human Synapsin-1
    Tags
    mCherry (Flp-dependent)
    Available Since
    Aug. 19, 2022
    Availability
    Academic Institutions and Nonprofits only

  20. pAAV-hSyn-fDIO-hM4D(Gi)-mCherry-WPREpA (AAV Retrograde)

    Viral Prep
    #154867-AAVrg
    Purpose
    Ready-to-use AAV Retrograde particles produced from pAAV-hSyn-fDIO-hM4D(Gi)-mCherry-WPREpA (#154867). In addition to the viral particles, you will also receive purified pAAV-hSyn-fDIO-hM4D(Gi)-mCherry-WPREpA plasmid DNA. Syn-driven, Flp-dependent hM4D(Gi) receptor with an mCherry reporter for CNO-induced neuronal inhibition. These AAV were produced with a retrograde serotype, which permits retrograde access to projection neurons. These AAV preparations are suitable purity for injection into animals.
    Depositor
    Ulrik Gether
    Article
    Runegaard et al eNeuro. 2018 Jun 18;5(3). pii: eN-NWR-03
    Promoter
    Human Synapsin-1
    Tags
    mCherry (Flp-dependent)
    Available Since
    Oct. 8, 2020
    Availability
    Academic Institutions and Nonprofits only
Showing: 101 - 120 of 10187 results