Addgene

We narrowed to 342 results for: Lrrk2;

Showing: 121 - 140 of 342 results

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pDEST51-LRRK2-R1441C

Plasmid

#25081

Depositor

Mark Cookson

Article

J Biol Chem. 2008 Jun 13;283(24):16906-1

Insert

LRRK2 (LRRK2 Human)

Use

Destination vector

Tags

6XHis and V5

Expression

Mammalian

Mutation

Arginine 1441 mutated to Cysteine

Promoter

Available since

June 17, 2010

Availability

Academic Institutions and Nonprofits only
BPK1520-LRRK2-G2019S-ng

Plasmid

#180436

Purpose

Transiently expressing a nicking sgRNA to facilitate the introduction of LRRK2-G2019S mutation in PE3 approach

Depositor

Frank Soldner

Article

Li et al Elife. 2022 Sep 7;11:e79208. doi: 10.755

Insert

ncRNA targeting LRRK2-G2019S (LRRK2 Human)

Use

CRISPR

Tags

Expression

Mammalian

Mutation

Promoter

U6

Available since

Nov. 1, 2022

Availability

Academic Institutions and Nonprofits only

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2XMyc-LRRK2-RCKW

Plasmid

#25064

Depositor

Mark Cookson

Article

J Biol Chem. 2008 Jun 13;283(24):16906-1

Insert

LRRK2 (LRRK2 Human)

Use

Tags

2XMyc

Expression

Mammalian

Mutation

Contains only the ROC-COR-Kinase-WD40 domains …

Promoter

Available since

June 29, 2010

Availability

Academic Institutions and Nonprofits only

Enlarge
2XMyc-LRRK2-Kinase

Plasmid

#25071

Depositor

Mark Cookson

Article

J Biol Chem. 2008 Jun 13;283(24):16906-1

Insert

LRRK2 (LRRK2 Human)

Use

Tags

2XMyc

Expression

Mammalian

Mutation

Contains only the kinase domain aa 1863-2218

Promoter

Available since

June 29, 2010

Availability

Academic Institutions and Nonprofits only
pDEST51-LRRK2-R1441G

Plasmid

#25082

Depositor

Mark Cookson

Article

J Biol Chem. 2008 Jun 13;283(24):16906-1

Insert

LRRK2 (LRRK2 Human)

Use

Destination vector

Tags

6XHis and V5

Expression

Mammalian

Mutation

Arginine 1441 mutated to Glycine

Promoter

Available since

June 17, 2010

Availability

Academic Institutions and Nonprofits only
2XMyc-LRRK2-WD40

Plasmid

#25073

Depositor

Mark Cookson

Article

J Biol Chem. 2008 Jun 13;283(24):16906-1

Insert

LRRK2 (LRRK2 Human)

Use

Tags

2XMyc

Expression

Mammalian

Mutation

Contains only the WD40 domain aa 2155-2527

Promoter

Available since

Nov. 1, 2011

Availability

Academic Institutions and Nonprofits only
3xFLAG-FKBP-LRRK2

Plasmid

#193584

Purpose

Expresses human full-length LRRK2 with FKBP domain and 3xFLAG situated at the N-terminus

Depositor

Mark Cookson

Article

Kluss et al Proc Natl Acad Sci U S A. 2022 Oct 25;11

Insert

Leucine-rich repeat kinase 2 (LRRK2 Human)

Use

Tags

3xFLAG and FKBP

Expression

Mammalian

Mutation

Promoter

CMV

Available since

Jan. 17, 2023

Availability

Academic Institutions and Nonprofits only

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2XMyc-LRRK2-LRRs

Plasmid

#25072

Depositor

Mark Cookson

Article

J Biol Chem. 2008 Jun 13;283(24):16906-1

Insert

LRRK2 (LRRK2 Human)

Use

Tags

2XMyc

Expression

Mammalian

Mutation

Contains only the LRR domains aa879-1278

Promoter

Available since

Nov. 1, 2011

Availability

Academic Institutions and Nonprofits only
2XMyc-LRRK2-COR

Plasmid

#25069

Depositor

Mark Cookson

Article

J Biol Chem. 2008 Jun 13;283(24):16906-1

Insert

LRRK2 (LRRK2 Human)

Use

Tags

2XMyc

Expression

Mammalian

Mutation

Contains only the COR domain aa1408-1850

Promoter

Available since

Nov. 1, 2011

Availability

Academic Institutions and Nonprofits only
2XMyc-LRRK2-RCK

Plasmid

#25065

Depositor

Mark Cookson

Article

J Biol Chem. 2008 Jun 13;283(24):16906-1

Insert

LRRK2 (LRRK2 Human)

Use

Tags

2XMyc

Expression

Mammalian

Mutation

Contains only the ROC-COR-Kinase domains aa 1329…

Promoter

Available since

June 29, 2010

Availability

Academic Institutions and Nonprofits only
LRRK2 gRNA (BRDN0001146754)

Plasmid

#77330

Purpose

3rd generation lentiviral gRNA plasmid targeting human LRRK2

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

LRRK2 (LRRK2 Human)

Use

CRISPR and Lentiviral

Tags

Expression

Mammalian

Mutation

Promoter

hU6

Available since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

Enlarge
pDEST51-LRRK2-Y1699C

Plasmid

#25084

Depositor

Mark Cookson

Article

J Biol Chem. 2008 Jun 13;283(24):16906-1

Insert

LRRK2 (LRRK2 Human)

Use

Destination vector

Tags

6XHis and V5

Expression

Mammalian

Mutation

Tyrosine 1699 mutated to Cysteine

Promoter

Available since

July 2, 2010

Availability

Academic Institutions and Nonprofits only
pDEST53-LRRK2-K1347A

Plasmid

#25052

Depositor

Mark Cookson

Article

Greggio et al Neurobiol Dis. 2006 Aug . 23(2):329-41.

Insert

LRRK2 (LRRK2 Human)

Use

Tags

GFP

Expression

Mammalian

Mutation

Lysine 1347 mutated to Alanine

Promoter

Available since

June 29, 2010

Availability

Academic Institutions and Nonprofits only
pDEST53-LRRK2-ROC

Plasmid

#25053

Depositor

Mark Cookson

Article

Greggio et al Neurobiol Dis. 2006 Aug . 23(2):329-41.

Insert

LRRK2 (LRRK2 Human)

Use

Tags

GFP

Expression

Mammalian

Mutation

Contains only the ROC domain- aa 1333-1516

Promoter

Available since

Nov. 1, 2011

Availability

Academic Institutions and Nonprofits only
2XMyc-LRRK2-deltaHeat

Plasmid

#25068

Depositor

Mark Cookson

Article

J Biol Chem. 2008 Jun 13;283(24):16906-1

Insert

LRRK2 (LRRK2 Human)

Use

Tags

2XMyc

Expression

Mammalian

Mutation

Contains the LRR-ROC-COR-Kinase-WD40 domains; Del…

Promoter

Available since

Nov. 1, 2011

Availability

Academic Institutions and Nonprofits only
LRRK2 gRNA (BRDN0001148003)

Plasmid

#77332

Purpose

3rd generation lentiviral gRNA plasmid targeting human LRRK2

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

LRRK2 (LRRK2 Human)

Use

CRISPR and Lentiviral

Tags

Expression

Mammalian

Mutation

Promoter

hU6

Available since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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LRRK2 gRNA (BRDN0001147881)

Plasmid

#77333

Purpose

3rd generation lentiviral gRNA plasmid targeting human LRRK2

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

LRRK2 (LRRK2 Human)

Use

CRISPR and Lentiviral

Tags

Expression

Mammalian

Mutation

Promoter

hU6

Available since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

Enlarge
pDEST51-LRRK2-I1371V

Plasmid

#29399

Depositor

Mark Cookson

Insert

LRRK2 (LRRK2 Human)

Use

Destination vector

Tags

6XHis and V5

Expression

Mammalian

Mutation

Ile1371Val

Promoter

Available since

April 1, 2011

Availability

Academic Institutions and Nonprofits only
pDEST51-LRRK2-R1441H

Plasmid

#25083

Depositor

Mark Cookson

Article

J Biol Chem. 2008 Jun 13;283(24):16906-1

Insert

LRRK2 (LRRK2 Human)

Use

Destination vector

Tags

6XHis and V5

Expression

Mammalian

Mutation

Arg 1441 mutated to His

Promoter

Available since

June 17, 2010

Availability

Academic Institutions and Nonprofits only
pBACgus/LRRK2 C-His

Plasmid

#40375

Depositor

Michael J Fox Foundation MJFF

Insert

LRRK2 (LRRK2 Human)

Use

Baculovirus

Tags

6xHis

Expression

Mutation

WT

Promoter

polH

Available since

Oct. 1, 2012

Availability

Industry, Academic Institutions, and Nonprofits

Enlarge