We narrowed to 160,253 results for: Gene

1. Human messenger-RBP sgRNA library

   Pooled Library

   #168791

   Purpose

   CRISPR library targets sub-pool of human mRNA binding proteins

   Depositor

   Martin Turner

   Article

   Turner et al CRISPR J. 2021 Jun;4(3):427-437. doi: 10

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   CRISPR and Lentiviral

   Available since

   July 30, 2021

   Availability

   Academic Institutions and Nonprofits only

2. p11-3’_8xN_PAM-site1 (RTW554)

   Pooled Library

   #160132

   Purpose

   Plasmid library harboring a randomized 8nt PAM 3’ of target site 1. Can be used to profile CRISPR-Cas PAM requirements of enzymes that recognize 3’ PAMs (e.g. Cas9)

   Depositor

   Keith Joung, Benjamin Kleinstiver

   Article

   Walton et al Nat Protoc. 2021 Feb 5. pii: 10.1038/s41

   Species

   Synthetic

   Use

   CRISPR

   Available since

   Feb. 8, 2021

   Availability

   Academic Institutions and Nonprofits only

3. Human Genome-Wide Reduced Double-gRNA library

   Pooled Library

   #137999

   Purpose

   This gRNA library targets the human coding genome, aimed to reduce the scale of genome-wide perturbation screens up to fivefold compared to conventional methods, without sacrificing performance.

   Depositor

   Leopold Parts

   Article

   Peets et al bioRxiv 859652

   Species

   Homo sapiens

   Use

   CRISPR and Lentiviral

   Available since

   Oct. 15, 2020

   Availability

   Academic Institutions and Nonprofits only

4. p11-5’_10xN_PAM-site4 (RTW574)

   Pooled Library

   #160135

   Purpose

   Plasmid library harboring a randomized 10nt PAM 5’ of target site 4. Can be used to profile CRISPR-Cas PAM requirements of enzymes that recognize 5’ PAMs (e.g. Cas12a)

   Depositor

   Keith Joung, Benjamin Kleinstiver

   Article

   Walton et al Nat Protoc. 2021 Feb 5. pii: 10.1038/s41

   Species

   Synthetic

   Use

   CRISPR

   Available since

   Feb. 8, 2021

   Availability

   Academic Institutions and Nonprofits only

5. p11-3’_8xN_PAM-site2 (RTW555)

   Pooled Library

   #160133

   Purpose

   Plasmid library harboring a randomized 8nt PAM 3’ of target site 2. Can be used to profile CRISPR-Cas PAM requirements of enzymes that recognize 3’ PAMs (e.g. Cas9)

   Depositor

   Keith Joung, Benjamin Kleinstiver

   Article

   Walton et al Nat Protoc. 2021 Feb 5. pii: 10.1038/s41

   Species

   Synthetic

   Use

   CRISPR

   Available since

   Feb. 8, 2021

   Availability

   Academic Institutions and Nonprofits only

6. Perturb-seq GBC library

   Pooled Library

   #85968

   Purpose

   Perturb-seq GBC library

   Depositor

   Jonathan Weissman

   Article

   Adamson et al Cell. 2016 Dec 15;167(7):1867-1882.e21.

   Expression

   Mammalian

   Use

   CRISPR and Lentiviral

   Available since

   Feb. 14, 2017

   Availability

   Academic Institutions and Nonprofits only

7. FNLCR CRISPRa Cell Surface

   Pooled Library

   #207471

   Purpose

   CRISPR-based activation library with guide RNAs targeting all cell surface proteins.

   Depositor

   Raj Chari

   Article

   Yang et al Sci Adv. 2024 Feb 16;10(7):eadj2445. doi

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   CRISPR and Lentiviral

   Available since

   Jan. 24, 2024

   Availability

   Academic Institutions and Nonprofits only

8. mTF-CRISPRai

   Pooled Library

   #122131

   Purpose

   Expresses gRNAs for mouse transcription factor-CRISPR activation

   Depositor

   Stanley Qi

   Article

   Liu et al Cell Stem Cell. 2018 Sep 28. pii: S1934-

   Expression

   Mammalian

   Species

   Mus musculus

   Use

   CRISPR and Lentiviral

   Available since

   April 25, 2019

   Availability

   Academic Institutions and Nonprofits only

9. lentiGuide-Puro-pKO-library

   Pooled Library

   #190744

   Purpose

   CRISPR/Cas9 paired-guide RNA library to delete proximal poly(A) sites in mouse melanoma.

   Depositor

   Robert Bradley

   Article

   Gabel et al Nat Commun. 2024 Feb 1;15(1):959. doi: 1

   Expression

   Mammalian

   Species

   Mus musculus

   Use

   CRISPR, Lentiviral, and Mouse Targeting

   Available since

   Feb. 2, 2024

   Availability

   Academic Institutions and Nonprofits only

10. KSHV Tiling Library

    Pooled Library

    #180272

    Purpose

    sgRNA library tiling entire ~154 kb of the BAC16 Kaposi’s Sarcoma-associated Herpes viral genome. A guide every ~8 bp allows pooled screening of viral genome.

    Depositor

    Britt Glaunsinger

    Article

    Morgens et al PLoS Pathog. 2022 Jan 18;18(1):e1010236.

    Expression

    Mammalian

    Species

    Kaposi’s sarcoma-associated herpes virus

    Use

    Lentiviral

    Available since

    Feb. 11, 2022

    Availability

    Academic Institutions and Nonprofits only