We narrowed to 15,273 results for: grn

Showing: 2001 - 2020 of 15273 results

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pGL3-U6-pegRNA_SRD5A3-EGFP

Plasmid

#159781

Purpose

S. pyogenes pegRNA for C to A mutation at the SRD5A3 site of human cells using prime editing

Depositor

Xiaolong Wang

Publication

Liu et al Cell Discov. 2020 Apr 28;6:27. doi: 10.1

Has service

50 µg Transfection-Ready DNA and 100 µg Transfection-Ready DNA

Insert

spacer of pegRNA targeting SRD5A3 gene (SRD5A3 Human)

Expression

Mammalian

Available since

Oct. 20, 2020

Availability

Academic Institutions and Nonprofits only

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Lenti sgRNA CFP

Plasmid

#155281

Purpose

Lentiviral sgRNA cloning with CFP marker

Depositor

Martin Carroll

Type

Empty backbone

Available since

Sept. 4, 2020

Availability

Academic Institutions and Nonprofits only

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pDONR-U6gRNA-PGKpuro2ABFP

Plasmid

#136405

Purpose

Donor vector for gRNA subcloning. Required for gRNA cloning into the RCAS-DV. Also constitutively expresses Puromycin linked to TagBFP.

Depositor

Massimo Squatrito

Publication

Oldrini et al Nat Commun. 2018 Apr 13;9(1):1466. doi:

Type

Empty backbone

Use

CRISPR

Mutation

BbsI restriction site at position 437 was removed…

Promoter

U6, PDK

Available since

Aug. 10, 2020

Availability

Academic Institutions and Nonprofits only

Cited by

1 Article

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pDONR-U6gRNA-PGKpuro2APDGFB

Plasmid

#136409

Purpose

Donor vector for gRNA subcloning. Required for gRNA cloning into the RCAS-DV. Also constitutively expresses PDGFB.

Depositor

Massimo Squatrito

Publication

Oldrini et al Nat Commun. 2018 Apr 13;9(1):1466. doi:

Type

Empty backbone

Use

CRISPR

Mutation

BbsI restriction site in the PDGFB sequence (Glu1…

Promoter

U6, PDK

Available since

Aug. 10, 2020

Availability

Academic Institutions and Nonprofits only

Cited by

1 Article

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pU6-pegRNA-EMX1+38

Plasmid

#140579

Purpose

Expresses a pegRNA in mammalian cells

Depositor

Feng Zhang

Publication

Schmid-Burgk et al Mol Cell. 2020 Mar 17. pii: S1097-2765(2

Has service

50 µg Transfection-Ready DNA and 100 µg Transfection-Ready DNA

Insert

pegRNA EMX1 +38

Available since

May 21, 2020

Availability

Academic Institutions and Nonprofits only

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pU6-pegRNA-HEK3+24

Plasmid

#140577

Purpose

Expresses a pegRNA in mammalian cells

Depositor

Feng Zhang

Publication

Schmid-Burgk et al Mol Cell. 2020 Mar 17. pii: S1097-2765(2

Has service

50 µg Transfection-Ready DNA and 100 µg Transfection-Ready DNA

Insert

pegRNA HEK3 +24

Available since

May 21, 2020

Availability

Academic Institutions and Nonprofits only

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pU6-pegRNA-DNMT1+38

Plasmid

#140578

Purpose

Expresses a pegRNA in mammalian cells

Depositor

Feng Zhang

Publication

Schmid-Burgk et al Mol Cell. 2020 Mar 17. pii: S1097-2765(2

Has service

50 µg Transfection-Ready DNA and 100 µg Transfection-Ready DNA

Insert

pegRNA DNMT1 +38

Available since

May 21, 2020

Availability

Academic Institutions and Nonprofits only

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px330-UFL1 sgRNA2

Plasmid

#134636

Purpose

contains sgRNA targeting human UFL1 for gene knockout

Depositor

Yihong Ye

Publication

Wang et al Cell Res. 2020 Jan;30(1):5-20. doi: 10.1

Has service

50 µg Transfection-Ready DNA and 100 µg Transfection-Ready DNA

Insert

UFL1 sgRNA2 (UFL1 Human)

Expression

Mammalian

Available since

Nov. 19, 2019

Availability

Academic Institutions and Nonprofits only

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DKC1 F2.3 gRNA

Plasmid

#90653

Purpose

3rd generation lentiviral gRNA plasmid targeting human DKC1

Depositor

Iain Cheeseman

Publication

McKinley et al Dev Cell. 2017 Feb 27;40(4):405-420.e2.

Insert

DKC1 (Guide Designation F2.3)

Use

CRISPR and Lentiviral

Promoter

U6

Available since

May 31, 2019

Availability

Academic Institutions and Nonprofits only

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pJL1-mRFP1 gRNA

Plasmid

#117052

Purpose

In vitro expression of anti-mRFP1 Cas9 sgRNA from the T7 promoter

Depositor

Michael Jewett

Publication

Stark et al ACS Synth Biol. 2019 May 7. doi: 10.1021

Insert

anti-mRFP1 SpCas9 gRNA

Expression

Bacterial

Promoter

T7

Available since

May 8, 2019

Availability

Academic Institutions and Nonprofits only

Cited by

1 Article

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pSpCas9_BB_2A-GFP_MAPRE3-gRNA#2

Plasmid

#107730

Purpose

Knock out of EB3 in human cells by CRISPR/Cas9

Depositor

Torsten Wittmann

Publication

van Haren et al Nat Cell Biol. 2018 Jan 29. pii: 10.1038

Has service

50 µg Transfection-Ready DNA and 100 µg Transfection-Ready DNA

Insert

MAPRE3 gRNA #2 (targets Exon 1) (MAPRE3 Human)

Expression

Mammalian

Promoter

U6

Available since

May 1, 2018

Availability

Academic Institutions and Nonprofits only

Cited by

1 Article

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pSpCas9_BB_2A-GFP_MAPRE3-gRNA#1

Plasmid

#107729

Purpose

Knock out of EB3 in human cells by CRISPR/Cas9

Depositor

Torsten Wittmann

Publication

van Haren et al Nat Cell Biol. 2018 Jan 29. pii: 10.1038

Has service

50 µg Transfection-Ready DNA and 100 µg Transfection-Ready DNA

Insert

MAPRE3 gRNA #1 (targets Exon 1) (MAPRE3 Human)

Expression

Mammalian

Promoter

U6

Available since

May 1, 2018

Availability

Academic Institutions and Nonprofits only

Cited by

1 Article

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lentiCRISPRv2-TTF-1-gRNA

Plasmid

#101857

Purpose

Introducing a gRNA targeting human TTF-1 (NKX2-1) into cells

Depositor

David Mu

Publication

Lai et al Oncogene. 2018 Mar 19. pii: 10.1038/s413

Insert

gRNA targeting TTF-1 (NKX2-1 Human)

Use

Lentiviral

Available since

Oct. 25, 2017

Availability

Academic Institutions and Nonprofits only

Cited by

1 Article

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AAV_Actb NHEJ donor_U6_sgRNA_EF1a_GFP_polyA

Plasmid

#97310

Purpose

NHEJ donor for fusing a p2A-mCherry reporter to mouse Actb. EGFP driven by EF1a promoter and U6-driven sgRNAs targeting Actb. AAV backbone.

Depositor

Hui Yang

Publication

Yao et al Cell Res. 2017 May 19. doi: 10.1038/cr.2

Insert

Actb NHEJ donor

Use

AAV and Mouse Targeting

Expression

Mammalian

Promoter

U6, EF1a

Available since

Sept. 6, 2017

Availability

Academic Institutions and Nonprofits only

Cited by

1 Article

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hgRNA-A51_pLKO-Hyg

Plasmid

#100567

Purpose

hgRNA-A51 in a lentiviral backbone

Depositor

George Church

Publication

Kalhor et al Nat Methods. 2017 Feb;14(2):195-200. doi

Insert

hgRNA-A51

Use

CRISPR, Lentiviral, and Synthetic Biology

Expression

Mammalian

Available since

Aug. 25, 2017

Availability

Academic Institutions and Nonprofits only

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hgRNA-G21_pLKO-Hyg

Plasmid

#100565

Purpose

hgRNA-G21 in a lentiviral backbone

Depositor

George Church

Publication

Kalhor et al Nat Methods. 2017 Feb;14(2):195-200. doi

Insert

hgRNA-G21

Use

CRISPR, Lentiviral, and Synthetic Biology

Expression

Mammalian

Available since

Aug. 25, 2017

Availability

Academic Institutions and Nonprofits only

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hgRNA-E21_pLKO-Hyg

Plasmid

#100563

Purpose

hgRNA-E21 in a lentiviral backbone

Depositor

George Church

Publication

Kalhor et al Nat Methods. 2017 Feb;14(2):195-200. doi

Insert

hgRNA-E21

Use

CRISPR, Lentiviral, and Synthetic Biology

Expression

Mammalian

Available since

Aug. 25, 2017

Availability

Academic Institutions and Nonprofits only

Cited by

1 Article

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PPP2R5C B11.5 gRNA

Plasmid

#90853

Purpose

3rd generation lentiviral gRNA plasmid targeting human PPP2R5C

Depositor

Iain Cheeseman

Publication

McKinley et al Dev Cell. 2017 Feb 27;40(4):405-420.e2.

Insert

PPP2R5C (Guide Designation B11.5)

Use

CRISPR and Lentiviral

Promoter

U6

Available since

July 25, 2017

Availability

Academic Institutions and Nonprofits only

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PPP2R2A B5.5 gRNA

Plasmid

#90847

Purpose

3rd generation lentiviral gRNA plasmid targeting human PPP2R2A

Depositor

Iain Cheeseman

Publication

McKinley et al Dev Cell. 2017 Feb 27;40(4):405-420.e2.

Insert

PPP2R2A (Guide Designation B5.5)

Use

CRISPR and Lentiviral

Promoter

U6

Available since

July 25, 2017

Availability

Academic Institutions and Nonprofits only

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NAE1 G8.3 gRNA

Plasmid

#90777

Purpose

3rd generation lentiviral gRNA plasmid targeting human NAE1

Depositor

Iain Cheeseman

Publication

McKinley et al Dev Cell. 2017 Feb 27;40(4):405-420.e2.

Insert

NAE1 (Guide Designation G8.3)

Use

CRISPR and Lentiviral

Promoter

U6

Available since

July 24, 2017

Availability

Academic Institutions and Nonprofits only

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