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pLV-Hyg-Snrnp40-skywarp-CRISPR-resistant

Plasmid

#134252

Purpose

Lentivector encoding CRISPR-resistant skywarp form of Snrnp40 (missing exon 5)

Depositor

Bruce Beutler

Article

Zhang et al Nat Immunol. 2019 Oct;20(10):1322-1334.

Insert

Snrp40 (Snrnp40 Mouse)

Use

Lentiviral

Tags

Expression

Mammalian

Mutation

deleted amino acids 179-219, and mutated coding s…

Promoter

EF1a

Available since

March 19, 2020

Availability

Academic Institutions and Nonprofits only

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TLCV2-Exoc7-Ex5&10

Plasmid

#133303

Purpose

EGFP reporter sequence was removed from TLCV2 vector and two gRNAs targeting mouse Exoc7 gene were cloned into the modified TLCV2 vector.

Depositor

Jingshi Shen

Article

Wang et al J Biol Chem. 2019 Dec 27;294(52):19988-1

Insert

Exocyst complex component 7 (Exoc7 Mouse)

Use

CRISPR and Lentiviral

Tags

Expression

Mammalian

Mutation

Promoter

mU6 promoter

Available since

Nov. 15, 2019

Availability

Academic Institutions and Nonprofits only

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pKLV2-U6(gDmap1 v2)-PGK-Puro-BFP

Plasmid

#117141

Purpose

Express gRNA vs Dmap1

Depositor

Kosuke Yusa

Article

Yu et al Stem Cells. 2019 Apr 1. doi: 10.1002/ste

Insert

gDmap1 v2 (Dmap1 Synthetic)

Use

CRISPR and Lentiviral

Tags

Expression

Mutation

Deleted BbsI site within WPRE, modified BFP

Promoter

human U6 promoter, mouse PGK promoter

Available since

April 26, 2019

Availability

Academic Institutions and Nonprofits only

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pLKO.1-shDnd1-No6

Plasmid

#70067

Purpose

TRC lentiviral vector for shRNA against mouse Dnd1 #6

Depositor

Thomas Tuschl

Article

Yamaji et al Nature. 2017 Mar 23;543(7646):568-572. d

Insert

Dnd1 (Dnd1 Mouse)

Use

Lentiviral

Tags

Expression

Mammalian

Mutation

Promoter

EF1alpha

Available since

Nov. 22, 2017

Availability

Academic Institutions and Nonprofits only
AOI-WT-Cas9-sg-mouse Gfi1-exon5 (F3)-GFP

Plasmid

#91884

Purpose

Expresses 3xFLAG-Cas9 and a gRNA targeting mouse Gfi1

Depositor

Martine Roussel

Article

Vo et al Cell Rep. 2017 Mar 21;18(12):2907-2917.

Insert

gRNA targeting Gfi1 (Gfi1 Mouse)

Use

CRISPR

Tags

Expression

Mammalian

Mutation

Promoter

U6

Available since

July 19, 2017

Availability

Academic Institutions and Nonprofits only
AURKA gRNA (BRDN0001145351)

Plasmid

#77728

Purpose

3rd generation lentiviral gRNA plasmid targeting human AURKA

Depositor

David Root, John Doench

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

AURKA (AURKA Human)

Use

CRISPR and Lentiviral

Tags

Expression

Mammalian

Mutation

Promoter

hU6

Available since

July 13, 2016

Availability

Academic Institutions and Nonprofits only

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AURKC gRNA (BRDN0001146500)

Plasmid

#78054

Purpose

3rd generation lentiviral gRNA plasmid targeting human AURKC

Depositor

David Root, John Doench

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

AURKC (AURKC Human)

Use

CRISPR and Lentiviral

Tags

Expression

Mammalian

Mutation

Promoter

hU6

Available since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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DGKH gRNA (BRDN0001144863)

Plasmid

#78043

Purpose

3rd generation lentiviral gRNA plasmid targeting human DGKH

Depositor

David Root, John Doench

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

DGKH (DGKH Human)

Use

CRISPR and Lentiviral

Tags

Expression

Mammalian

Mutation

Promoter

hU6

Available since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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DGKH gRNA (BRDN0001487100)

Plasmid

#78044

Purpose

3rd generation lentiviral gRNA plasmid targeting human DGKH

Depositor

David Root, John Doench

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

DGKH (DGKH Human)

Use

CRISPR and Lentiviral

Tags

Expression

Mammalian

Mutation

Promoter

hU6

Available since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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DGKH gRNA (BRDN0001149163)

Plasmid

#78045

Purpose

3rd generation lentiviral gRNA plasmid targeting human DGKH

Depositor

David Root, John Doench

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

DGKH (DGKH Human)

Use

CRISPR and Lentiviral

Tags

Expression

Mammalian

Mutation

Promoter

hU6

Available since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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CDK5R1 gRNA (BRDN0001147725)

Plasmid

#77853

Purpose

3rd generation lentiviral gRNA plasmid targeting human CDK5R1

Depositor

David Root, John Doench

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

CDK5R1 (CDK5R1 Human)

Use

CRISPR and Lentiviral

Tags

Expression

Mammalian

Mutation

Promoter

hU6

Available since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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IKBKE gRNA (BRDN0001148875)

Plasmid

#77771

Purpose

3rd generation lentiviral gRNA plasmid targeting human IKBKE

Depositor

David Root, John Doench

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

IKBKE (IKBKE Human)

Use

CRISPR and Lentiviral

Tags

Expression

Mammalian

Mutation

Promoter

hU6

Available since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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LRPPRC gRNA (BRDN0001145923)

Plasmid

#77775

Purpose

3rd generation lentiviral gRNA plasmid targeting human LRPPRC

Depositor

David Root, John Doench

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

LRPPRC (LRPPRC Human)

Use

CRISPR and Lentiviral

Tags

Expression

Mammalian

Mutation

Promoter

hU6

Available since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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GRK4 gRNA (BRDN0001145215)

Plasmid

#77723

Purpose

3rd generation lentiviral gRNA plasmid targeting human GRK4

Depositor

David Root, John Doench

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

GRK4 (GRK4 Human)

Use

CRISPR and Lentiviral

Tags

Expression

Mammalian

Mutation

Promoter

hU6

Available since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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AK4 gRNA (BRDN0001148207)

Plasmid

#77693

Purpose

3rd generation lentiviral gRNA plasmid targeting human AK4

Depositor

David Root, John Doench

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

AK4 (AK4 Human)

Use

CRISPR and Lentiviral

Tags

Expression

Mammalian

Mutation

Promoter

hU6

Available since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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CERKL gRNA (BRDN0001148191)

Plasmid

#77675

Purpose

3rd generation lentiviral gRNA plasmid targeting human CERKL

Depositor

David Root, John Doench

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

CERKL (CERKL Human)

Use

CRISPR and Lentiviral

Tags

Expression

Mammalian

Mutation

Promoter

hU6

Available since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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CARD11 gRNA (BRDN0001145385)

Plasmid

#77678

Purpose

3rd generation lentiviral gRNA plasmid targeting human CARD11

Depositor

David Root, John Doench

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

CARD11 (CARD11 Human)

Use

CRISPR and Lentiviral

Tags

Expression

Mammalian

Mutation

Promoter

hU6

Available since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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CARD11 gRNA (BRDN0001144917)

Plasmid

#77680

Purpose

3rd generation lentiviral gRNA plasmid targeting human CARD11

Depositor

David Root, John Doench

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

CARD11 (CARD11 Human)

Use

CRISPR and Lentiviral

Tags

Expression

Mammalian

Mutation

Promoter

hU6

Available since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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KALRN gRNA (BRDN0001146234)

Plasmid

#77637

Purpose

3rd generation lentiviral gRNA plasmid targeting human KALRN

Depositor

David Root, John Doench

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

KALRN (KALRN Human)

Use

CRISPR and Lentiviral

Tags

Expression

Mammalian

Mutation

Promoter

hU6

Available since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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DAPK3 gRNA (BRDN0001162290)

Plasmid

#77557

Purpose

3rd generation lentiviral gRNA plasmid targeting human DAPK3

Depositor

David Root, John Doench

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

DAPK3 (DAPK3 Human)

Use

CRISPR and Lentiviral

Tags

Expression

Mammalian

Mutation

Promoter

hU6

Available since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

Enlarge