We narrowed to 2,556 results for: neurod

1. MLM3636-Prnp-CDS-Neg

   Plasmid

   #61856

   Purpose

   Expresses a gRNA plasmid targeting the prion gene's exon 3, negative strand

   Depositor

   Gerold Schmitt-Ulms

   Article

   Mehrabian et al PLoS One. 2014 Dec 9;9(12):e114594. doi:

   Insert

   PrP guiding sequence (Prnp Mouse)
   

   Use

   CRISPR

   Expression

   Mammalian

   Promoter

   hU6 promoter

   Available Since

   Feb. 3, 2015

   Availability

   Academic Institutions and Nonprofits only

2. pTWIN1-His6-Ssp-Htt2-90(A2C)-37Q

   Plasmid

   #114617

   Purpose

   Bacterial expression of Htt fragment containing amino acids 2-90, with A2C cysteine mutation and a 37 polyQ repeat

   Depositor

   Hilal Lashuel

   Article

   Warner JB et al J Am Chem Soc. 2017 Oct 18;139(41):14456

   Insert

   Huntingtin Exon1 fragment (HTT Human)
   

   Tags

   His6-Ssp DnaB intein

   Expression

   Bacterial

   Mutation

   A2C; 23 polyQ repeat

   Available Since

   Oct. 5, 2018

   Availability

   Academic Institutions and Nonprofits only

   

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3. pTWIN1-His6-Ssp-Httex1-43Q-A2C

   Plasmid

   #114622

   Purpose

   Bacterial expression of Htt fragment containing exon 1, with A2C cysteine mutation and a 43 polyQ repeat

   Depositor

   Hilal Lashuel

   Article

   Warner JB et al J Am Chem Soc. 2017 Oct 18;139(41):14456

   Insert

   Huntingtin Exon1 (HTT Human)
   

   Tags

   His6-Ssp DnaB intein

   Expression

   Bacterial

   Mutation

   A2C; 43 polyQ repeat

   Available Since

   Sept. 18, 2018

   Availability

   Academic Institutions and Nonprofits only

   

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4. pTWIN1-His6-Ssp-Httex1-43Q-A2C-A60C

   Plasmid

   #114623

   Purpose

   Bacterial expression of Htt fragment containing exon 1, with A2C & A60C cysteine mutations and a 43 polyQ repeat

   Depositor

   Hilal Lashuel

   Article

   Warner JB et al J Am Chem Soc. 2017 Oct 18;139(41):14456

   Insert

   Huntingtin Exon1 (HTT Human)
   

   Tags

   His6-Ssp DnaB intein

   Expression

   Bacterial

   Mutation

   A2C, A60C; 43 polyQ repeat

   Available Since

   Sept. 19, 2018

   Availability

   Academic Institutions and Nonprofits only

   

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5. pTWIN1-His6-Ssp-Htt2-90(A2C)-49Q

   Plasmid

   #114627

   Purpose

   Bacterial expression of Htt fragment containing amino acids 2-90, with A2C cysteine mutation and a 49 polyQ repeat

   Depositor

   Hilal Lashuel

   Article

   Warner JB et al J Am Chem Soc. 2017 Oct 18;139(41):14456

   Insert

   Huntingtin Exon1 fragment (HTT Human)
   

   Tags

   His6-Ssp DnaB intein

   Expression

   Bacterial

   Mutation

   A2C; 49 polyQ repeat

   Available Since

   Sept. 19, 2018

   Availability

   Academic Institutions and Nonprofits only

   

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6. pTWIN1-His6-Ssp-Htt2-90-49Q-P90C

   Plasmid

   #114631

   Purpose

   Bacterial expression of Htt fragment containing amino acids 2-90, with P90C cysteine mutation and a 49 polyQ repeat

   Depositor

   Hilal Lashuel

   Article

   Warner JB et al J Am Chem Soc. 2017 Oct 18;139(41):14456

   Insert

   Huntingtin Exon1 fragment (HTT Human)
   

   Tags

   His6-Ssp DnaB intein

   Expression

   Bacterial

   Mutation

   P90C; 49 polyQ repeat

   Available Since

   Sept. 18, 2018

   Availability

   Academic Institutions and Nonprofits only

   

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7. GAK gRNA (BRDN0001146687)

   Plasmid

   #76470

   Purpose

   3rd generation lentiviral gRNA plasmid targeting human GAK

   Depositor

   John Doench, David Root

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Insert

   GAK (GAK Human)
   

   Use

   CRISPR and Lentiviral

   Expression

   Mammalian

   Promoter

   hU6

   Available Since

   July 6, 2016

   Availability

   Academic Institutions and Nonprofits only

   

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8. pLentiCRISPR V2 puro HTRA2 sg2

   Plasmid

   #244864

   Purpose

   Knockout of human HTRA2

   Depositor

   Alexis Jourdain

   Article

   Harhai et al Cell Rep. 2025 Jul 25;44(8):116069. doi:

   Insert

   HTRA2 sgRNA (HTRA2 Human)
   

   Use

   CRISPR and Lentiviral

   Promoter

   U6

   Available Since

   Oct. 15, 2025

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

9. pLentiCRISPR V2 puro HTRA2 sg1

   Plasmid

   #244863

   Purpose

   Knockout of human HTRA2

   Depositor

   Alexis Jourdain

   Article

   Harhai et al Cell Rep. 2025 Jul 25;44(8):116069. doi:

   Insert

   HTRA2 sgRNA (HTRA2 Human)
   

   Use

   CRISPR and Lentiviral

   Promoter

   U6

   Available Since

   Oct. 15, 2025

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

10. AAV-CAG-GRN-HA

    Plasmid

    #243760

    Purpose

    AAV plasmid expressing human GRN with a C-terminal HA tag under the CAG promoter.

    Depositor

    Andrew Arrant

    Article

    Nader et al Sci Rep. 2025 Jul 19;15(1):26217. doi: 1

    Insert

    Progranulin (GRN Human)
    

    Use

    AAV

    Tags

    HA Tag

    Promoter

    CAG

    Available Since

    Oct. 8, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

11. pCMV mTagBFP2-2A-CHMP2B-Q165X

    Plasmid

    #232001

    Purpose

    Bicistronic expression of CHMP2B Q165X mutant along with an mTagBFP2 transfection marker, connected via 2A sequences.

    Depositor

    Franz-Ulrich Hartl

    Article

    Sitron et al Mol Cell. 2025 Sep 18;85(18):3505-3523.e

    Insert

    CHMP2B (CHMP2B Human)
    

    Expression

    Mammalian

    Mutation

    Q165X

    Available Since

    Aug. 22, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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12. pCMV CHMP2B-L4D F5D-3XHA

    Plasmid

    #232003

    Purpose

    Expression of a CHMP2B membrane binding mutant (L4D F5D) with a 3xHA tag.

    Depositor

    Franz-Ulrich Hartl

    Article

    Sitron et al Mol Cell. 2025 Sep 18;85(18):3505-3523.e

    Insert

    CHMP2B (CHMP2B Human)
    

    Tags

    3xHA

    Expression

    Mammalian

    Mutation

    L4D F5D

    Available Since

    Aug. 22, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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13. pEF1a FLAG-CHMP2B-d55-96

    Plasmid

    #232013

    Purpose

    Expression of FLAG-tagged CHMP2B with the second alpha helix deleted.

    Depositor

    Franz-Ulrich Hartl

    Article

    Sitron et al Mol Cell. 2025 Sep 18;85(18):3505-3523.e

    Insert

    CHMP2B (CHMP2B Human)
    

    Use

    Lentiviral

    Tags

    FLAG

    Expression

    Mammalian

    Mutation

    Δ55-96

    Available Since

    Aug. 22, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

14. pSPcas9(BB)-2A-Puro V2.0 sgCHMP2B-2 aauucccaaaugaagauggc

    Plasmid

    #231998

    Purpose

    Expression of an sgRNA targeting CHMP2B, Cas9, and a PuroR marker

    Depositor

    Franz-Ulrich Hartl

    Article

    Sitron et al Mol Cell. 2025 Sep 18;85(18):3505-3523.e

    Insert

    CHMP2B-targeted sgRNA (CHMP2B Human)
    

    Use

    CRISPR

    Expression

    Mammalian

    Available Since

    Aug. 22, 2025

    Availability

    Academic Institutions and Nonprofits only

15. EF1a-FXN-P2A-mRuby2(miRE.FF4)-TS.FF6x1-bGH

    Plasmid

    #235301

    Purpose

    ComMAND open-loop circuit regulating FXN-P2A-mRuby2 (therapeutically relevant gene)

    Depositor

    Kate Galloway

    Article

    Love et al Cell Syst. 2025 Apr 22:101269. doi: 10.1

    Insert

    FXN-P2A-mRuby2 (FXN Human)
    

    Use

    Synthetic Biology

    Expression

    Mammalian

    Promoter

    EF1a (human EF1a)

    Available Since

    June 11, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

16. EF1a-FXN-P2A-mRuby2-bGH

    Plasmid

    #235300

    Purpose

    ComMAND base gene regulating FXN-P2A-mRuby2 (therapeutically relevant gene)

    Depositor

    Kate Galloway

    Article

    Love et al Cell Syst. 2025 Apr 22:101269. doi: 10.1

    Insert

    FXN-P2A-mRuby2 (FXN Human)
    

    Use

    Synthetic Biology

    Expression

    Mammalian

    Promoter

    EF1a (human EF1a)

    Available Since

    May 30, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

17. EF1a-FXN-P2A-mRuby2(miRE.FF4)-TS.FF4x1-bGH

    Plasmid

    #235302

    Purpose

    ComMAND closed-loop circuit regulating FXN-P2A-mRuby2 (therapeutically relevant gene)

    Depositor

    Kate Galloway

    Article

    Love et al Cell Syst. 2025 Apr 22:101269. doi: 10.1

    Insert

    FXN-P2A-mRuby2 (FXN Human)
    

    Use

    Synthetic Biology

    Expression

    Mammalian

    Promoter

    EF1a (human EF1a)

    Available Since

    May 30, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

18. pUC19_msfGFP-FUS-repair-tempate

    Plasmid

    #237684

    Purpose

    For knock-in msfGFP to FUS locus

    Depositor

    Denes Hnisz

    Article

    Zhang et al Nature. 2025 Jun 4. doi: 10.1038/s41586-

    Insert

    FUS (FUS Human)
    

    Use

    CRISPR

    Tags

    msfGFP

    Available Since

    May 6, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

19. A1-LCD allW D262V

    Plasmid

    #234616

    Purpose

    Bacterial expression of N-terminally 6His tagged hnRNPA1 LCD (186-320) D262V with all aromatic amino acids mutated to W keeping the hexapeptide fibril core (SYNDFG) intact.

    Depositor

    Tanja Mittag

    Article

    Das et al bioRxiv [Preprint]. 2024 Mar 3:2024.02.2

    Insert

    hnRNPA1_LCD_allW D262V (HNRNPA1 Human)
    

    Tags

    6xHis-TEV

    Expression

    Bacterial

    Mutation

    C-terminal domain (186-320) bearing familial ALS …

    Promoter

    T7

    Available Since

    April 15, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

20. A1-LCD allW D262N

    Plasmid

    #234615

    Purpose

    Bacterial expression of N-terminally 6His tagged hnRNPA1 LCD (186-320) D262N with all aromatic amino acids mutated to W keeping the hexapeptide fibril core (SYNDFG) intact.

    Depositor

    Tanja Mittag

    Article

    Das et al bioRxiv [Preprint]. 2024 Mar 3:2024.02.2

    Insert

    hnRNPA1_LCD_allW D262N (HNRNPA1 Human)
    

    Tags

    6xHis-TEV

    Expression

    Bacterial

    Mutation

    C-terminal domain (186-320) bearing familial ALS …

    Promoter

    T7

    Available Since

    April 15, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge