We narrowed to 2,289 results for: ung

Showing: 2201 - 2220 of 2289 results

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pDONR223_NKX2-1_DelCTerm_1-223AA

Plasmid

#221476

Purpose

Gateway cloning of NKX2-1 C-terminal truncation mutation overexpression

Depositor

Matthew Meyerson

Publication

Pulice et al bioRxiv [Preprint]. 2023 Oct 27:2023.10.

Insert

NKX2-1 (NKX2-1 Human)

Use

Gateway Cloning

Mutation

Deletion of 224-371AA C-terminal domain

Available since

July 2, 2024

Availability

Academic Institutions and Nonprofits only

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pDONR223_NKX2-1_DelNTerm_160-371AA

Plasmid

#221475

Purpose

Gateway cloning of NKX2-1 N-terminal truncation mutation overexpression

Depositor

Matthew Meyerson

Publication

Pulice et al bioRxiv [Preprint]. 2023 Oct 27:2023.10.

Insert

NKX2-1 (NKX2-1 Human)

Use

Gateway Cloning

Mutation

Deletion of 1-159AA N-terminal domain

Available since

July 2, 2024

Availability

Academic Institutions and Nonprofits only

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pLX-EF1a_NKX2-1_V205F

Plasmid

#221485

Purpose

NKX2-1 V205F DNA binding mutation lentiviral overexpression

Depositor

Matthew Meyerson

Publication

Pulice et al bioRxiv [Preprint]. 2023 Oct 27:2023.10.

Insert

NKX2-1 (NKX2-1 Human)

Use

Lentiviral

Tags

V5

Expression

Mammalian

Mutation

V205F

Promoter

EF1a

Available since

July 1, 2024

Availability

Academic Institutions and Nonprofits only

Cited by

1 Article

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pEK21

Plasmid

#210586

Purpose

Reporter gene expression in B. dendrobatidis

Depositor

Lillian Fritz-Laylin

Publication

Kalinka et al Proc Natl Acad Sci U S A. 2024 Jan 23;12

Insert

BdTUBA1pro-Hshph-G4S-nanoluc-ScADH1ter

Use

Luciferase

Tags

NanoLuc luciferase

Expression

Bacterial and Yeast

Promoter

BdTUBA1pro

Available since

Jan. 22, 2024

Availability

Academic Institutions and Nonprofits only

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pEK23

Plasmid

#210595

Purpose

Reporter gene expression in B. dendrobatidis

Depositor

Lillian Fritz-Laylin

Publication

Kalinka et al Proc Natl Acad Sci U S A. 2024 Jan 23;12

Insert

BdH4pro-Hshph-G4S-nanoluc-ScADH1ter

Use

Luciferase

Tags

NanoLuc luciferase

Expression

Bacterial and Yeast

Promoter

BdH4pro

Available since

Jan. 22, 2024

Availability

Academic Institutions and Nonprofits only

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pEK24

Plasmid

#210597

Purpose

Reporter gene expression in B. dendrobatidis

Depositor

Lillian Fritz-Laylin

Publication

Kalinka et al Proc Natl Acad Sci U S A. 2024 Jan 23;12

Insert

BdACTINpro-Hshph-G4S-nanoluc-ScADH1ter

Use

Luciferase

Tags

NanoLuc luciferase

Expression

Bacterial and Yeast

Promoter

BdACTINpro

Available since

Jan. 22, 2024

Availability

Academic Institutions and Nonprofits only

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pAd-PR.Cre

Plasmid

#192936

Purpose

Adenoviral expression vector encoding sgRNAs targeting Trp53 and Rb1 and Cre

Depositor

Thorsten Stiewe

Publication

Merle et al Mol Cancer. 2022 Oct 3;21(1):191. doi: 1

Inserts

Trp53 (Trp53 Mouse)
Rb1 (Rb1 Mouse)

Use

Adenoviral

Expression

Mammalian

Promoter

U6

Available since

Dec. 12, 2022

Availability

Industry, Academic Institutions, and Nonprofits

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pAd-PR.CC9

Plasmid

#192935

Purpose

Adenoviral expression vector encoding sgRNAs targeting Trp53 and Rb1, Cre and Cas9

Depositor

Thorsten Stiewe

Publication

Merle et al Mol Cancer. 2022 Oct 3;21(1):191. doi: 1

Inserts

Trp53 (Trp53 Mouse)
Rb1 (Rb1 Mouse)

Use

Adenoviral

Expression

Mammalian

Promoter

U6

Available since

Dec. 9, 2022

Availability

Academic Institutions and Nonprofits only

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pU6-gRNA(SFTPCI73Tcorr)-SpCas9(BB)-2A-GFP

Plasmid

#187647

Purpose

Encodes gRNA to correct the SFTPC I73T mutation

Depositor

Darrell Kotton

Publication

Alysandratos et al Cell Rep. 2021 Aug 31;36(9):109636. doi:

Insert

I73T gRNA

Use

CRISPR

Available since

Aug. 31, 2022

Availability

Academic Institutions and Nonprofits only

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pB6-Hipp11-tdTomato cre reporter-FNF-DTA

Plasmid

#183024

Purpose

B6J Hipp11-pCAG-loxP-FNF-bGHpA-3xSV40pA-loxP-tdTomato-WPRE-bpA allele targeting vector, low copy number

Depositor

Mario Capecchi

Insert

tdTomato

Use

Cre/Lox and Mouse Targeting

Expression

Bacterial and Mammalian

Available since

April 28, 2022

Availability

Academic Institutions and Nonprofits only

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pFB-U6-Chrnb4-gRNA-hSyn-mCherry-WPRE-SV40pA

Plasmid

#128345

Purpose

pAAV encoding gRNA sequence for loss-of-function indels

Depositor

Ryan Drenan

Publication

Peng et al Eur J Neurosci. 2018 May 19. doi: 10.111

Insert

Chrnb4 (Chrnb4 Mouse)

Use

CRISPR

Expression

Mammalian

Available since

July 19, 2019

Availability

Academic Institutions and Nonprofits only

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pFB-U6-Chrnb3-gRNA-hSyn-mCherry-WPRE-SV40pA

Plasmid

#128344

Purpose

pAAV encoding gRNA sequence for loss-of-function indels

Depositor

Ryan Drenan

Publication

Peng et al Eur J Neurosci. 2018 May 19. doi: 10.111

Insert

Chrnb3 (Chrnb3 Mouse)

Use

CRISPR

Expression

Mammalian

Available since

July 19, 2019

Availability

Academic Institutions and Nonprofits only

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pFB-U6-Chrna6-gRNA-hSyn-mCherry-WPRE-SV40pA

Plasmid

#128341

Purpose

pAAV encoding gRNA sequence for loss-of-function indels

Depositor

Ryan Drenan

Publication

Peng et al Eur J Neurosci. 2018 May 19. doi: 10.111

Insert

Chrna6 (Chrna6 Mouse)

Use

CRISPR

Expression

Mammalian

Available since

July 19, 2019

Availability

Academic Institutions and Nonprofits only

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BPK4387 - human expression plasmid for SpCas9 Cluster 5

Plasmid

#101191

Purpose

Human expression plasmid for SpCas9 Cluster 5 variant: CMV-T7-hSpCas9-Cluster5(K918A, V922A, R925A)-NLS(SV40)-3xFLAG

Depositor

Jennifer Doudna, Keith Joung

Publication

Chen et al Nature. 2017 Sep 20. doi: 10.1038/nature

Insert

hSpCas9-Cluster5(K918A/V922A/R925A)

Tags

3x FLAG and NLS (SV40)

Expression

Mammalian

Mutation

K918A/V922A/R925A

Promoter

CMV

Available since

Sept. 29, 2017

Availability

Academic Institutions and Nonprofits only

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pCIneoRL-Notch1 3'UTR-mir200c-mut

Plasmid

#84596

Purpose

Renilla Luciferase reporter assay for NOTCH1 3'UTR with mutations on miR-200c binding site

Depositor

Yanan Yang

Publication

Zhang et al Nat Commun. 2016 Jul 26;7:12231. doi: 10

Insert

NOTCH1 3'UTR (NOTCH1 Human)

Use

Luciferase

Tags

Renilla Luciferase

Mutation

Mutation on miR-200c binding site on NOTCH1 3…

Promoter

CMV

Available since

Nov. 4, 2016

Availability

Academic Institutions and Nonprofits only
pCIneoRL-BCL2 3'UTR-mir200c-mut

Plasmid

#84598

Purpose

Renilla Luciferase reporter assay for BCL2 3'UTR with mutations on miR-200c binding site

Depositor

Yanan Yang

Publication

Zhang et al Nat Commun. 2016 Jul 26;7:12231. doi: 10

Insert

BCL2 3'UTR (UTS2R Human)

Use

Luciferase

Tags

Renilla Luciferase

Mutation

Mutation on miR-200c binding site on BCL2 3'…

Promoter

CMV

Available since

Nov. 4, 2016

Availability

Academic Institutions and Nonprofits only
pCIneoRL-TOB1 3'UTR-mir200c-mut

Plasmid

#84590

Purpose

Renilla Luciferase reporter assay for TOB1 3'UTR with mutations on miR-200c binding site

Depositor

Yanan Yang

Publication

Zhang et al Nat Commun. 2016 Jul 26;7:12231. doi: 10

Insert

TOB1 3'UTR (UTS2R Human)

Use

Luciferase

Tags

Renilla Luciferase

Mutation

Mutation on miR-200c binding site on TOB1 3'…

Promoter

CMV

Available since

Nov. 4, 2016

Availability

Academic Institutions and Nonprofits only
pCIneoRL-RanBP93'UTR-mir200c-mut

Plasmid

#84592

Purpose

Renilla Luciferase reporter assay for RANBP9 3'UTR with mutations on miR-200c binding site

Depositor

Yanan Yang

Publication

Zhang et al Nat Commun. 2016 Jul 26;7:12231. doi: 10

Insert

RANBP9 3'UTR (RANBP9 Human)

Use

Luciferase

Tags

Renilla Luciferase

Mutation

Mutation on miR-200c binding site on RANBP9 3…

Promoter

CMV

Available since

Nov. 4, 2016

Availability

Academic Institutions and Nonprofits only
pcDNA3.1-Hmga2 shMut wt

Plasmid

#52036

Purpose

encodes shMut HMGA2

Depositor

Julian Downward

Publication

Kumar et al Nature. 2014 Jan 9;505(7482):212-7. doi:

Insert

Hmga2 (Hmga2 Mouse)

Expression

Mammalian

Mutation

shRNA binding site mutated

Promoter

CMV

Available since

June 10, 2014

Availability

Academic Institutions and Nonprofits only
pUC19-U6-SpCas9_gRNA-OPA1-del_exon5-gRNA1a_(CJT90)

Plasmid

#226989

Purpose

pUC19 plasmid with U6 promoter and SpCas9 gRNA to create an OPA1-del_exon5 cell line via nuclease mediate excision, gRNA 1a must be used with gRNA 2a or 2b

Depositor

Benjamin Kleinstiver

Publication

Fry et al EMBO J. 2024 Feb;43(3):391-413. doi: 10.

Insert

SpCas9 gRNA 1a to create OPA1-del_exon5

Use

CRISPR

Expression

Mammalian

Promoter

U6

Available since

Nov. 21, 2024

Availability

Academic Institutions and Nonprofits only

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