We narrowed to 15,903 results for: grna

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PECAM1-3'gRNA

Plasmid

#235606

Purpose

gRNA targeting PECAM1 3' terminal for CRISPR-Cas9-mediated knock-in

Depositor

Kai Wang

Publication

Zhao et al Angiogenesis. 2025 Jan 3;28(1):10. doi:

Insert

PECAM1 gRNA (PECAM1 Human)

Use

CRISPR

Promoter

U6

Available since

June 17, 2025

Availability

Academic Institutions and Nonprofits only

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pLenti‐puro‐OgRNA_mdxE53

Plasmid

#187054

Purpose

SpCas9 gRNA correcting mdx4cv nonsense mutation with ABE

Depositor

Renzhi Han

Publication

Xu et al Nat Commun. 2021 Jun 17;12(1):3719. doi:

Insert

SpCas9 gRNA correcting mdx4cv nonsense mutation with ABE

Use

Lentiviral

Expression

Mammalian

Promoter

U6

Available since

Aug. 11, 2022

Availability

Academic Institutions and Nonprofits only

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pT7ddx19gRNA

Plasmid

#47932

Purpose

in vitro transcription of ddx19 gRNA

Depositor

Wenbiao Chen, Susan Wente

Publication

Jao et al Proc Natl Acad Sci U S A. 2013 Aug 20;11

Insert

ddx19 gRNA (ddx19 Zebrafish)

Use

CRISPR

Available since

Aug. 29, 2013

Availability

Academic Institutions and Nonprofits only

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pYPQAT22

Plasmid

#223394

Purpose

T-DNA vector for A3A/Y130F-CBE_V01 based C-to-T base editing for monocot plants; NG or NA PAM ; wide working window; A3A/Y130F-CBE_V01 was driven by ZmUbi1 and the sgRNA was driven by OsU3 promoter.

Depositor

Yiping Qi

Publication

Cheng et al Plant Cell. 2025 Apr 9:koaf081. doi: 10.

Insert

ZmUbi-hA3A-Y130F-SpRYD10A-UGI-OsU3-gRNA scaffold

Use

CRISPR

Tags

3x FLAG and NLS

Expression

Plant

Available since

May 28, 2025

Availability

Academic Institutions and Nonprofits only

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pYPQAT19

Plasmid

#223391

Purpose

T-DNA vector for A3A/Y130F-CBE_V01 based C-to-T base editing for dicot plants; NG or NA PAM ; wide working window; A3A/Y130F-CBE_V01 was driven by AtUBQ10 and the sgRNA was driven by AtU3 promoter.

Depositor

Yiping Qi

Publication

Cheng et al Plant Cell. 2025 Apr 9:koaf081. doi: 10.

Insert

AtUBQ10-hA3A-Y130F-SpRYD10A-UGI-AtU3-gRNA scaffold

Use

CRISPR

Tags

3x FLAG and NLS

Expression

Plant

Available since

April 10, 2025

Availability

Academic Institutions and Nonprofits only

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pXPR_016-sgATF4-3

Plasmid

#202456

Purpose

Expression of a guide RNA targeting ATF4

Depositor

William Hahn

Publication

Cervia et al Cancer Discov. 2023 Mar 1;13(3):766-795.

Insert

ATF4 gRNA (ATF4 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available since

July 25, 2023

Availability

Academic Institutions and Nonprofits only

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HP-Cas9hGem-Ade2-LEU2-LINEAR

Plasmid

#174839

Purpose

pRS414 backbone containing LINEAR fragment targeting ADE2 in H. polymorpha

Depositor

Zengyi Shao

Publication

Ploessl et al Nat Chem Biol. 2021 Oct 28. pii: 10.1038

Insert

HH-gRNA-HDV targetting ADE2 in Ogataea (para)polymorpha

Use

CRISPR and Synthetic Biology

Expression

Bacterial and Yeast

Promoter

TDH3p

Available since

Jan. 5, 2022

Availability

Academic Institutions and Nonprofits only

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pAAV-pMecp2-dSaCas9-VP64-pU6-sgRNA

Plasmid

#158972

Purpose

Vector C encodes pAAV-pMecp2-dSaCas9-VP64-spA-pU6-sgRNA (BsaI) transgenes for AAV packaging and expression of CRISPR activator in neurons

Depositor

Chung Tin

Publication

Lau et al Mol Ther Nucleic Acids. 2019 Jun 7;16:63

Insert

dSaCas9-VP64

Use

AAV and CRISPR

Expression

Mammalian

Promoter

pMecp2

Available since

Sept. 8, 2020

Availability

Academic Institutions and Nonprofits only

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pDGB3 alpha1 U6-26:gRNA 4 (Pnos):2.1 aptamer (GB1724)

Plasmid

#160621

Purpose

Target for the Nopaline Synthetase Promoter with the MS2 recognition 2.1 loop in position3' in the scaffold

Depositor

Diego Orzaez

Publication

Selma et al Plant Biotechnol J. 2019 Sep;17(9):1703-

Insert

U6-26:gRNA 4 (pNos): 2.1 aptamer

Use

CRISPR and Synthetic Biology

Expression

Plant

Mutation

BsaI and BsmBI sites removed

Promoter

U6-26

Available since

Jan. 14, 2021

Availability

Academic Institutions and Nonprofits only

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pX459-Lrp5 gRNA

Plasmid

#246548

Purpose

CRISPR vector co-expressing Cas9 and a mouse Lrp5 gRNA

Depositor

Mario Vallon

Publication

Heiden et al J Biol Chem. 2025 Sep 4:110682. doi: 10.

Insert

Lrp5 gRNA (Lrp5 Mouse)

Use

CRISPR

Promoter

U6

Available since

Dec. 3, 2025

Availability

Academic Institutions and Nonprofits only

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pX459-Fzd5 gRNA

Plasmid

#246564

Purpose

CRISPR vector co-expressing Cas9 and a mouse Fzd5 gRNA

Depositor

Mario Vallon

Publication

Heiden et al J Biol Chem. 2025 Sep 4:110682. doi: 10.

Insert

Fzd5 gRNA (Fzd5 Mouse)

Use

CRISPR

Promoter

U6

Available since

Dec. 2, 2025

Availability

Academic Institutions and Nonprofits only

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pDS48

Plasmid

#241839

Purpose

Cas9-gRNA construct targeting the UBE3A locus

Depositor

Albert Keung

Publication

Kelkar et al Front Cell Dev Biol. 2025 Aug 29;13:1665

Insert

Cas9-gRNA (UBE3A )

Use

AAV and CRISPR

Expression

Mammalian

Available since

Sept. 8, 2025

Availability

Academic Institutions and Nonprofits only

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pML107-VRG4

Plasmid

#232899

Purpose

Plasmid expressing Cas9 and gRNA TCGCATAGCCCAGTATACGT which targets the VRG4 gene.

Depositor

Jolanda Van Leeuwen

Publication

Batte et al Cell Syst. 2026 Mar 2:101515. doi: 10.10

Insert

VRG4 gRNA (VRG4 Budding Yeast)

Use

CRISPR

Expression

Yeast

Promoter

snR52

Available since

April 30, 2025

Availability

Academic Institutions and Nonprofits only

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AAV:ITR-EF1aCore-SaCas9-dual(U6-sgRNA(backbone))-ITR

Plasmid

#207878

Purpose

AAV vector encoding EF1a core promoter-driven SaCas9 and two sgRNA cloning sites w/ the engineered Sa Guide scaffold variant (BbsI and PaqCI for sgRNA cloning).

Depositor

Yeh-Hsing Lao

Publication

Lao et al Proc Natl Acad Sci U S A. 2023 Aug 22;12

Type

Empty backbone

Use

AAV and CRISPR

Expression

Mammalian

Available since

Oct. 13, 2023

Availability

Academic Institutions and Nonprofits only

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Lenti-sgPten#2/Cre

Plasmid

#173646

Purpose

Expresses a Pten-targeting gRNA and Cre-recombinase

Depositor

Charles Swanton

Publication

Cai et al Cancer Discov. 2021 Feb 19. pii: 2159-82

Insert

gRNA targeting Pten (Pten Mouse)

Use

CRISPR, Cre/Lox, and Lentiviral

Available since

June 7, 2022

Availability

Academic Institutions and Nonprofits only

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Lenti-sgEp300#1/Cre

Plasmid

#173591

Purpose

Expresses a Ep300-targeting gRNA and Cre-recombinase

Depositor

Charles Swanton

Publication

Cai et al Cancer Discov. 2021 Feb 19. pii: 2159-82

Insert

gRNA targeting Ep300 (Ep300 Mouse)

Use

CRISPR, Cre/Lox, and Lentiviral

Available since

June 7, 2022

Availability

Academic Institutions and Nonprofits only

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Lenti-sgTp53#2/Cre

Plasmid

#173621

Purpose

Expresses a Tp53-targeting gRNA and Cre-recombinase

Depositor

Charles Swanton

Publication

Cai et al Cancer Discov. 2021 Feb 19. pii: 2159-82

Insert

gRNA targeting Tp53 (Trp53 Mouse)

Use

CRISPR, Cre/Lox, and Lentiviral

Available since

June 7, 2022

Availability

Academic Institutions and Nonprofits only

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LsgRNA-FXR1-KH1-gRNA

Plasmid

#225483

Purpose

Express gRNA for FXR1

Depositor

Christine Mayr

Publication

Chen et al Cell. 5 August 2024. doi: 10.1016/j.cell

Insert

gRNA for editing FXR1-KH1 (FXR1 Human)

Use

CRISPR

Promoter

hU6

Available since

Oct. 9, 2024

Availability

Academic Institutions and Nonprofits only

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BPK1520-FXR1-N202S-gRNA

Plasmid

#225481

Purpose

Express gRNA for FXR1

Depositor

Christine Mayr

Publication

Chen et al Cell. 5 August 2024. doi: 10.1016/j.cell

Insert

gRNA for editing FXR1-N202S (FXR1 Human)

Use

CRISPR

Promoter

hU6

Available since

Oct. 8, 2024

Availability

Academic Institutions and Nonprofits only

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pU6-gRNA-TAZ

Plasmid

#86688

Purpose

Expresses a gRNA targeted to human TAZ

Depositor

William Pu

Publication

Wang et al Nat Protoc. 2017 Jan;12(1):88-103. doi:

Insert

U6-gRNA-TAZ (TAFAZZIN Human)

Use

CRISPR

Promoter

U6

Available since

March 2, 2017

Availability

Academic Institutions and Nonprofits only

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