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Plasmid#177419PurposeTo express Venus fused to the N-terminus of the Bcl-2 family chimera protein, Bcl-2-ActA: Bcl-2 with its membrane binding region swapped for ActA (mitochondrial targeting sequence).DepositorInsertBcl-2-ActA, Bcl2-acta, Bcl-acta
UseTagsVenusExpressionMammalianMutationPromoterCMVAvailable sinceJan. 3, 2023AvailabilityAcademic Institutions and Nonprofits only -
Venus-Bcl2-cb5-pEGFP-C1
Plasmid#177422PurposeTo express Venus fused to the N-terminus of the Bcl-2 family chimera protein, Bcl-2-Cb5: Bcl-2 with its membrane binding region swapped for Cb5 (ER targeting sequence).DepositorInsertBcl-2-Cb5, Bcl2-cb5, Bcl-cb5
UseTagsVenusExpressionMammalianMutationPromoterCMVAvailable sinceJan. 3, 2023AvailabilityAcademic Institutions and Nonprofits only -
pDONR221-B3GALT5
Plasmid#192719PurposeGateway entry vector encoding human B3GALT5DepositorInsertB3GALT5 (B3GALT5 Human)
UseGateway entry vectorTagsExpressionMutationM85TPromoterNoneAvailable sinceNov. 14, 2022AvailabilityAcademic Institutions and Nonprofits only -
pAIO-Ef1a-PE2-GFP:KCNQ2-C201R_pp
Plasmid#185061PurposeEf1a driven PE2 with pegRNA for editing C201R mutation (including silent PAM mutation) in KCNQ2. See Addgene plasmid #184445DepositorInsertU6:pegRNA:scaffold:PBS+RT template
UseCRISPR and LentiviralTagsExpressionMammalianMutationPromoterU6Available sinceNov. 7, 2022AvailabilityAcademic Institutions and Nonprofits only -
pT7-V5-SBP-C1-HsMex3C_1-225_AD
Plasmid#148497PurposeMammalian Expression of HsMex3C_1-225DepositorInsertHsMex3C_1-225 (MEX3C Human)
UseTagsExpressionMammalianMutationone non silent mutation compared to variant 2 fro…PromoterAvailable sinceNov. 1, 2022AvailabilityAcademic Institutions and Nonprofits only -
pT7-MS2-HA-C1-HsYTHDC2_1-1068_AD
Plasmid#148491PurposeMammalian Expression of HsYTHDC2_1-1068DepositorInsertHsYTHDC2_1-1068 (YTHDC2 Human)
UseTagsExpressionMammalianMutationone non silent mutation D233G and a deletion of 2…PromoterAvailable sinceNov. 1, 2022AvailabilityAcademic Institutions and Nonprofits only -
pT7-MS2-HA-C1-HsYTHDC2_1069-1430_AD
Plasmid#148492PurposeMammalian Expression of HsYTHDC2_1069-1430DepositorInsertHsYTHDC2_1069-1430 (YTHDC2 Human)
UseTagsExpressionMammalianMutationone non silent mutation L1409Q annotated as natur…PromoterAvailable sinceNov. 1, 2022AvailabilityAcademic Institutions and Nonprofits only -
p2151 pHAGE-hSPC-TFEB-TagBFP-W
Plasmid#188722PurposeLentiviral vector allowing for SFTPC-driven expression of TFEB:tagBFP fusion proteinDepositorInsertTFEB (TFEB Human)
UseLentiviralTagstagBFPExpressionMutationPromoterhSP-CAvailable sinceSept. 22, 2022AvailabilityAcademic Institutions and Nonprofits only -
pcDNA3.1(-) HuTF-Fc-His tag
Plasmid#183253PurposeSoluble expression of the extracellular domains of human tissue factor (TF)-FcDepositorInsertTissue factor (F3 Human)
UseTags8xHisExpressionMammalianMutationPromoterAvailable sinceAug. 18, 2022AvailabilityAcademic Institutions and Nonprofits only -
T11-HA-hORF1
Plasmid#185053Purposeexpression of human L1 ORF1 proteinDepositorInsertL1-hORF1
UseTagsHAExpressionMammalianMutationPromoterAvailable sinceAug. 15, 2022AvailabilityAcademic Institutions and Nonprofits only -
pT2iC6FAST1nls2ER4(#638)
Plasmid#184068Purposecyclofen-inducible YFAST nuclear relocation via mammalian cell transfection or mRNA synthesisDepositorInsertYFAST-2nls-ERT2
UseSynthetic BiologyTagsExpressionMammalianMutationERT2: G400V, M543A, L544A, deleted 1-281;PromotersCMV+SP6Available sinceJune 30, 2022AvailabilityAcademic Institutions and Nonprofits only -
pCSTG4FER3(#190)
Plasmid#184069Purposecyclofen-inducible GAL4 activation via mammalian cell transfection or mRNA synthesisDepositorInsertGal4bdFF-ERT2
UseSynthetic BiologyTagsExpressionMammalianMutationERT2: G400V, M543A, L544A, deleted 1-281;PromotersCMV+SP6Available sinceJune 28, 2022AvailabilityAcademic Institutions and Nonprofits only -
pX459-puro-hCASP8
Plasmid#185378PurposeFor mammalian expression of guide RNA: AAGCAATCTGTCCTTCCTGA that targets human CASP8 (Caspase 8)DepositorInsertCASP8 (CASP8 Human)
UseTagsExpressionMammalianMutationWTPromoterAvailable sinceJune 8, 2022AvailabilityAcademic Institutions and Nonprofits only -
pX459-puro-hARAF-1
Plasmid#185367PurposeFor mammalian expression of guide RNA: caccgTGGTCTACCGACTCATCAAG that targets human ARAFDepositorInsertARAF (ARAF Human)
UseTagsExpressionMammalianMutationWTPromoterAvailable sinceJune 7, 2022AvailabilityAcademic Institutions and Nonprofits only -
pLKO.1-PPP2R5A-1
Plasmid#179352PurposeshRNA suppressionDepositorInsertB56α
UseLentiviralTagsExpressionMammalianMutationPromoterAge1Available sinceFeb. 9, 2022AvailabilityAcademic Institutions and Nonprofits only -
pLKO.1-PPP2R5C-2
Plasmid#179356PurposeshRNA suppressionDepositorInsertB56γ
UseLentiviralTagsExpressionMammalianMutationPromoterAge1Available sinceFeb. 9, 2022AvailabilityAcademic Institutions and Nonprofits only -
pLKO.1-PPP2R3B-1
Plasmid#179360PurposeshRNA suppressionDepositorInsertPR48
UseLentiviralTagsExpressionMammalianMutationPromoterAge1Available sinceFeb. 9, 2022AvailabilityAcademic Institutions and Nonprofits only -
CNN3A-c007
Plasmid#175457PurposeProtein expression in bacterial cells. Lacking N-terminal 10 residues, G11-Y329.DepositorInsertCNN3 (CNN3 Human)
UseTagsHis6-SUMOExpressionBacterialMutationPromoterAvailable sinceJan. 27, 2022AvailabilityAcademic Institutions and Nonprofits only -
PLA2G6_Halo_C_allele
Plasmid#178166PurposeDonor vector for endogenous tagging of human PLA2G6 at the C-terminus with halotagInsertHalotag (PLA2G6 Human)
UseDonor vectorTagsExpressionMutationPromoterAvailable sinceDec. 2, 2021AvailabilityAcademic Institutions and Nonprofits only -
KCNC3_Halo_N_allele
Plasmid#178129PurposeDonor vector for endogenous tagging of human KCNC3 at the N-terminus with halotagInsertHalotag (KCNC3 Human)
UseDonor vectorTagsExpressionMutationPromoterAvailable sinceDec. 2, 2021AvailabilityAcademic Institutions and Nonprofits only -
pCHCHD3-donor
Plasmid#176347PurposeCRISPR donor plasmid to create GFP fusion proteinsDepositorInsertCHCHD3 (CHCHD3 Human)
UseCRISPRTagsGFPExpressionMutationPromoterAvailable sinceNov. 19, 2021AvailabilityAcademic Institutions and Nonprofits only -
pHDX-donor
Plasmid#176353PurposeCRISPR donor plasmid to create GFP fusion proteinsDepositorInsertHDX (HDX Human)
UseCRISPRTagsGFPExpressionMutationPromoterAvailable sinceNov. 12, 2021AvailabilityAcademic Institutions and Nonprofits only -
pDNAJC1-donor
Plasmid#176340PurposeCRISPR donor plasmid to create GFP fusion proteinsDepositorInsertDNAJC1 (DNAJC1 Human)
UseCRISPRTagsGFPExpressionMutationPromoterAvailable sinceNov. 12, 2021AvailabilityAcademic Institutions and Nonprofits only -
pFLAG GLTPD2
Plasmid#170745PurposeThe plasmids contain inserts (ORFs) for expressing various members of the GlycoLipid Transfer Protein (GLTP) superfamily.DepositorInsertGLTPD2 (GLTPD2 Human)
UseTagsFLAGExpressionMammalianMutationV49F, V152A and D209E- Please see depositor comme…PromoterAvailable sinceJuly 19, 2021AvailabilityAcademic Institutions and Nonprofits only -
pNK141d2
Plasmid#156377PurposeExpresses orthogonal RBS Sapphire reporterDepositorInsertSapphire
UseSynthetic BiologyTagsExpressionMutationPromoterAvailable sinceNov. 19, 2020AvailabilityAcademic Institutions and Nonprofits only -
Lentiviral human Citron shRNA 1 GFP
Plasmid#155286PurposeLentiviral expression of human CIT shRNA, GFP expression, based on Addgene 12247DepositorInsertCitron (CIT Human)
UseTagsExpressionMammalianMutationPromoterAvailable sinceAug. 31, 2020AvailabilityAcademic Institutions and Nonprofits only -
pHAGE-hSPC-TFEB(delta30)eGFP-W
Plasmid#126693PurposeLineage specific over expression of a mutated TFEB in lung alveolar epithelial cells, where TFEB is missing the first 30 amino acids of the sequence.DepositorInsertTFEB(delta30) (TFEB Human)
UseLentiviralTagsExpressionMutationDeleted amino acids 1-30, H32D, Deleted Stop Codo…PromoterhSPCAvailable sinceJuly 9, 2020AvailabilityAcademic Institutions and Nonprofits only -
TBXTA-c024
Plasmid#139761PurposeProtein expression/GST pull-downDepositorInsertTBXT, DNA-binding domain, G177D (TBXT Human)
UseTagsHis6-GST-TEVExpressionBacterialMutationG177D; contains only amino acids E41-D225PromoterT7Available sinceMay 6, 2020AvailabilityAcademic Institutions and Nonprofits only -
pCMV-GFP-RPS5pA
Plasmid#120194PurposeHuman RPS5 poly(A) site reporterDepositorInsertRPS5 poly(A) site
UseTagsExpressionMammalianMutationPromoterAvailable sinceApril 10, 2020AvailabilityAcademic Institutions and Nonprofits only -
pCMV-GFP-ILVBLpA
Plasmid#120205PurposeHuman ILVBL poly(A) site reporterDepositorInsertILVBL poly(A) site
UseTagsExpressionMammalianMutationPromoterAvailable sinceApril 7, 2020AvailabilityAcademic Institutions and Nonprofits only -
pCREB5.1.0-gDNA
Plasmid#132475PurposeCRISPR/Cas9 plasmid to create GFP fusion proteinsDepositorInsertCREB5 (CREB5 Human)
UseCRISPRTagsExpressionMutationPromoterAvailable sinceDec. 23, 2019AvailabilityAcademic Institutions and Nonprofits only -
pESRRG.1.0-gDNA
Plasmid#132473PurposeCRISPR/Cas9 plasmid to create GFP fusion proteinsDepositorInsertESRRG (ESRRG Human)
UseCRISPRTagsExpressionMutationPromoterAvailable sinceDec. 23, 2019AvailabilityAcademic Institutions and Nonprofits only -
pCSRNP3.1.0-gDNA
Plasmid#132472PurposeCRISPR/Cas9 plasmid to create GFP fusion proteinsDepositorInsertCSRNP3 (CSRNP3 Human)
UseCRISPRTagsExpressionMutationPromoterAvailable sinceDec. 23, 2019AvailabilityAcademic Institutions and Nonprofits only -
pHOXB6.1.0-gDNA
Plasmid#132458PurposeCRISPR/Cas9 plasmid to create GFP fusion proteinsDepositorInsertHOXB6 (HOXB6 Human)
UseCRISPRTagsExpressionMutationPromoterAvailable sinceDec. 19, 2019AvailabilityAcademic Institutions and Nonprofits only -
pGABPB2.1.0-gDNA
Plasmid#132457PurposeCRISPR/Cas9 plasmid to create GFP fusion proteinsDepositorInsertGABPB2 (GABPB2 Human)
UseCRISPRTagsExpressionMutationPromoterAvailable sinceDec. 19, 2019AvailabilityAcademic Institutions and Nonprofits only -
pGTF2I.1.0-gDNA
Plasmid#132452PurposeCRISPR/Cas9 plasmid to create GFP fusion proteinsDepositorInsertGTF2I (GTF2I Human)
UseCRISPRTagsExpressionMutationPromoterAvailable sinceDec. 18, 2019AvailabilityAcademic Institutions and Nonprofits only -
pKLF10.1.0-gDNA
Plasmid#132433PurposeCRISPR/Cas9 plasmid to create GFP fusion proteinsDepositorInsertKLF10 (KLF10 Human)
UseCRISPRTagsExpressionMutationPromoterAvailable sinceDec. 11, 2019AvailabilityAcademic Institutions and Nonprofits only -
pZNF695.1.0-gDNA
Plasmid#112445PurposeCRISPR plasmid for expression of Cas9 and gRNA targeting human transcription factor ZNF695DepositorInsertZNF695 (ZNF695 Human)
UseCRISPRTagsExpressionMammalianMutationPromoterAvailable sinceApril 11, 2019AvailabilityAcademic Institutions and Nonprofits only -
pZNF778-donor
Plasmid#112379PurposeCRISPR donor plasmid to tag human transcription factor ZNF778 with GFPDepositorInsertZNF778 homology arms flanking EGFP-IRES-Neo cassette (ZNF778 Human)
UseCRISPRTagsExpressionMutationrs4785627,rs28415940,rs9921361,rs28638280,rs60437…PromoterAvailable sinceDec. 17, 2018AvailabilityAcademic Institutions and Nonprofits only -
pZNF696-donor
Plasmid#113806PurposeCRISPR donor plasmid to tag human transcription factor ZNF696 with GFPDepositorInsertZNF696 homology arms flanking EGFP-IRES-Neo cassette (ZNF696 Human)
UseCRISPRTagsExpressionMutationrs7386259, rs3750217, rs7387702PromoterAvailable sinceDec. 11, 2018AvailabilityAcademic Institutions and Nonprofits only -
pTCF15.1.0-gDNA
Plasmid#113798PurposeCRISPR plasmid for expression of Cas9 and gRNA targeting human transcription factor TCF15DepositorInsertTCF15 (TCF15 Human)
UseCRISPRTagsExpressionMammalianMutationPromoterAvailable sinceDec. 11, 2018AvailabilityAcademic Institutions and Nonprofits only -
pZSCAN18.1.0-gDNA
Plasmid#113789PurposeCRISPR plasmid for expression of Cas9 and gRNA targeting human transcription factor ZSCAN18DepositorInsertZSCAN18 (ZSCAN18 Human)
UseCRISPRTagsExpressionMammalianMutationPromoterAvailable sinceDec. 11, 2018AvailabilityAcademic Institutions and Nonprofits only -
pSATB1.1.0-gDNA
Plasmid#113786PurposeCRISPR plasmid for expression of Cas9 and gRNA targeting human transcription factor SATB1DepositorInsertSATB1 (SATB1 Human)
UseCRISPRTagsExpressionMammalianMutationPromoterAvailable sinceDec. 11, 2018AvailabilityAcademic Institutions and Nonprofits only -
pZFP3.1.0-gDNA
Plasmid#113779PurposeCRISPR plasmid for expression of Cas9 and gRNA targeting human transcription factor ZFP3DepositorInsertZFP3 (ZFP3 Human)
UseCRISPRTagsExpressionMammalianMutationPromoterAvailable sinceDec. 11, 2018AvailabilityAcademic Institutions and Nonprofits only -
pTCFL5.1.0-gDNA
Plasmid#113775PurposeCRISPR plasmid for expression of Cas9 and gRNA targeting human transcription factor TCFL5DepositorInsertTCFL5 (TCFL5 Human)
UseCRISPRTagsExpressionMammalianMutationPromoterAvailable sinceDec. 11, 2018AvailabilityAcademic Institutions and Nonprofits only -
pZNF215.1.0-gDNA
Plasmid#113771PurposeCRISPR plasmid for expression of Cas9 and gRNA targeting human transcription factor ZNF215DepositorInsertZNF215 (ZNF215 Human)
UseCRISPRTagsExpressionMammalianMutationPromoterAvailable sinceDec. 11, 2018AvailabilityAcademic Institutions and Nonprofits only -
pZNF444.1.0-gDNA
Plasmid#112482PurposeCRISPR plasmid for expression of Cas9 and gRNA targeting human transcription factor ZNF444DepositorInsertZNF444 (ZNF444 Human)
UseCRISPRTagsExpressionMammalianMutationPromoterAvailable sinceDec. 10, 2018AvailabilityAcademic Institutions and Nonprofits only -
pZNF250.1.0-gDNA
Plasmid#112479PurposeCRISPR plasmid for expression of Cas9 and gRNA targeting human transcription factor ZNF250DepositorInsertZNF250 (ZNF250 Human)
UseCRISPRTagsExpressionMammalianMutationPromoterAvailable sinceDec. 10, 2018AvailabilityAcademic Institutions and Nonprofits only -
pZNF211.1.0-gDNA
Plasmid#112478PurposeCRISPR plasmid for expression of Cas9 and gRNA targeting human transcription factor ZNF211DepositorInsertZNF211 (ZNF211 Human)
UseCRISPRTagsExpressionMammalianMutationPromoterAvailable sinceDec. 10, 2018AvailabilityAcademic Institutions and Nonprofits only -
pZNF397.1.0-gDNA
Plasmid#112477PurposeCRISPR plasmid for expression of Cas9 and gRNA targeting human transcription factor ZNF397DepositorInsertZNF397 (ZNF397 Human)
UseCRISPRTagsExpressionMammalianMutationPromoterAvailable sinceDec. 10, 2018AvailabilityAcademic Institutions and Nonprofits only