We narrowed to 2,936 results for: NAK

1. pHAGE2-TetOminiCMV-OSM

   Plasmid

   #136555

   Purpose

   Dox-inducible polycistronic reprogramming lentiviral vector expressing mouse Oct4, Sox2, cMyc

   Depositor

   Hans Schöler

   Article

   Velychko et al Cell Stem Cell. 2019 Oct 30. pii: S1934-

   Insert

   Oct4-P2A-Sox2-E2A-cMyc (Myc, Pou5f1, Sox2 Mouse)
   

   Use

   Lentiviral

   Tags

   Expression

   Bacterial

   Mutation

   Promoter

   tetO-miniCMV (dox-inducible)

   Available since

   March 25, 2020

   Availability

   Academic Institutions and Nonprofits only

   

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2. pXPR_BRD003-sgWRN3

   Plasmid

   #125773

   Purpose

   constitutive expression of a guide RNA targeting human WRN

   Depositor

   Francisca Vazquez

   Article

   Chan et al Nature. 2019 Apr 10. pii: 10.1038/s41586

   Insert

   sgWRN3 (WRN Human)
   

   Use

   CRISPR

   Tags

   Expression

   Mutation

   Promoter

   Available since

   June 11, 2019

   Availability

   Academic Institutions and Nonprofits only

   

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3. pAAV-Ai14-luc

   Plasmid

   #87118

   Purpose

   AAV backbone plasmid including luc-pA knock-in donor and Ai14gRNA for HITI

   Depositor

   Juan Belmonte

   Article

   Suzuki et al Nature. 2016 Dec 1;540(7631):144-149. do

   Insert

   U6-Ai14sgRNA-Luciferase-nEF-GFPKASH-hGHpA
   

   Use

   AAV, CRISPR, and Luciferase

   Tags

   Expression

   Mutation

   Promoter

   Available since

   March 30, 2017

   Availability

   Academic Institutions and Nonprofits only

   

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4. AAV-FLEX-CAG_G-PTEN

   Plasmid

   #227438

   Purpose

   An AAV backbone for expression of the G-PTEN sensor under the CAG promoter, in a Cre dependent manner.

   Depositor

   Tal Laviv

   Article

   Kagan et al Nat Methods. 2025 Apr;22(4):764-777. doi

   Insert

   G-PTEN sensor (Pten Rat)
   

   Use

   AAV

   Tags

   CD-sREACh and mEGFP

   Expression

   Mammalian

   Mutation

   R14G

   Promoter

   pCAG

   Available since

   April 23, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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5. pcDNA3.1-HA-RAD52-∆C

   Plasmid

   #235677

   Purpose

   Expresses HA-tagged mutant human RAD52 in mammalian cells with a C-terminal deletion (Δ302-410 amino acids).

   Depositor

   Simon Powell

   Article

   Jalan et al Nat Commun. 2024 Sep 5;15(1):7776. doi:

   Insert

   RAD52 (RAD52 Human)
   

   Use

   Tags

   HA

   Expression

   Mammalian

   Mutation

   deleted amino acids 302-410

   Promoter

   Available since

   April 8, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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6. His-GST-TEV-BRD4(42-459) BD1-BD2

   Plasmid

   #233887

   Purpose

   pGex for protein overexpression of human BRD4

   Depositor

   Alessio Ciulli

   Article

   Hsia et al Nature. 2024 Mar;627(8002):204-211. doi:

   Insert

   BRD4 (BRD4 Human)
   

   Use

   Tags

   His-GST-TEV

   Expression

   Bacterial

   Mutation

   Promoter

   T7

   Available since

   March 11, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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7. pcs2-MTSmut-cox8A(XXXX)-GFP-IRES-mCherry

   Plasmid

   #226104

   Purpose

   Stability reporter construct of the COX8A mitochondrial targeting sequence (MTS) with mutations that impair recognition by SIFI for transient expression in mammalian cells

   Depositor

   Michael Rape

   Article

   Haakonsen et al Nature. 2024 Feb;626(8000):874-880. doi:

   Insert

   COX8A (COX8A Human)
   

   Use

   Tags

   GFP

   Expression

   Mammalian

   Mutation

   encodes only for mitochondrial targeting sequence…

   Promoter

   Available since

   Oct. 9, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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8. pLX304-EZH1-Y727F

   Plasmid

   #203582

   Purpose

   Expresses V5-tagged mutant version of EZH1 partially resistant to JQ-EZ-05 in mammalian cells.

   Depositor

   William Kaelin, Abhishek Chakraborty

   Article

   Chakraborty et al Sci Transl Med. 2017 Jul 12;9(398):eaal5

   Insert

   EZH1 (EZH1 Human)
   

   Use

   Lentiviral

   Tags

   V5-tagged

   Expression

   Mammalian

   Mutation

   changed Tyrosine 727 to Phenylalanine for partial…

   Promoter

   CMV

   Available since

   Feb. 22, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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9. pLX304-EZH1-dPSET

   Plasmid

   #203586

   Purpose

   Expresses V5-tagged mutant version of EZH1 with deletion of aa 744-747 and partially resistant to JQ-EZ-05 in mammalian cells.

   Depositor

   William Kaelin, Abhishek Chakraborty

   Article

   Chakraborty et al Sci Transl Med. 2017 Jul 12;9(398):eaal5

   Insert

   EZH1 (EZH1 Human)
   

   Use

   Lentiviral

   Tags

   V5-tagged

   Expression

   Mammalian

   Mutation

   deletion of aa 744-747 and partial resistance to …

   Promoter

   CMV

   Available since

   Feb. 22, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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10. pLX304-EZH1-D745N

    Plasmid

    #203585

    Purpose

    Expresses V5-tagged mutant version of EZH1 partially resistant to JQ-EZ-05 in mammalian cells.

    Depositor

    William Kaelin, Abhishek Chakraborty

    Article

    Chakraborty et al Sci Transl Med. 2017 Jul 12;9(398):eaal5

    Insert

    EZH1 (EZH1 Human)
    

    Use

    Lentiviral

    Tags

    V5-tagged

    Expression

    Mammalian

    Mutation

    changed Aspartic Acid 745 to Asparagine for parti…

    Promoter

    CMV

    Available since

    Feb. 22, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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11. pU6-gRNA(SFTPCI73Tcorr)-SpCas9(BB)-2A-GFP

    Plasmid

    #187647

    Purpose

    Encodes gRNA to correct the SFTPC I73T mutation

    Depositor

    Darrell Kotton

    Article

    Alysandratos et al Cell Rep. 2021 Aug 31;36(9):109636. doi:

    Insert

    I73T gRNA
    

    Use

    CRISPR

    Tags

    Expression

    Mutation

    Promoter

    Available since

    Aug. 31, 2022

    Availability

    Academic Institutions and Nonprofits only

    

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12. pnCS_DSep2_Peanut-TEV-Strep

    Plasmid

    #174495

    Purpose

    bacterial co-expression of Drosophila Sep2 and of Drosophila Peanut

    Depositor

    Manos Mavrakis

    Article

    Iv et al J Cell Sci. 2021 Jul 8. pii: 270842. doi

    Inserts

    Sep2 (Sep2 Fly)
    peanut (pnut Fly)
    

    Use

    Tags

    TEV-Strep

    Expression

    Bacterial

    Mutation

    Promoter

    Available since

    Sept. 29, 2021

    Availability

    Academic Institutions and Nonprofits only

    

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13. pLKO.1-puro-shRPS6

    Plasmid

    #125780

    Purpose

    constitutive expression of a short-hairpin RNA targeting human RPS6 (RNAi positive control)

    Depositor

    Francisca Vazquez

    Article

    Chan et al Nature. 2019 Apr 10. pii: 10.1038/s41586

    Insert

    shRPS6 (RPS6 Human)
    

    Use

    RNAi

    Tags

    Expression

    Mutation

    Promoter

    Available since

    June 4, 2019

    Availability

    Academic Institutions and Nonprofits only

    

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14. pXPR_BRD003-sgCh2-2

    Plasmid

    #125767

    Purpose

    constitutive expression of a guide RNA targeting an intergenic region of human chromosome 2 (CRISPR cutting control)

    Depositor

    Francisca Vazquez

    Article

    Chan et al Nature. 2019 Apr 10. pii: 10.1038/s41586

    Insert

    sgCh2-2
    

    Use

    CRISPR

    Tags

    Expression

    Mutation

    Promoter

    Available since

    June 4, 2019

    Availability

    Academic Institutions and Nonprofits only

    

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15. pXPR_BRD003-sgCh2-4

    Plasmid

    #125768

    Purpose

    constitutive expression of a guide RNA targeting an intergenic region of human chromosome 2 (CRISPR cutting control)

    Depositor

    Francisca Vazquez

    Article

    Chan et al Nature. 2019 Apr 10. pii: 10.1038/s41586

    Insert

    sgCh2-4
    

    Use

    CRISPR

    Tags

    Expression

    Mutation

    Promoter

    Available since

    June 4, 2019

    Availability

    Academic Institutions and Nonprofits only

    

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16. His6-TEV-CRBN-midi

    Plasmid

    #215330

    Purpose

    CRBN midi construct for use in crystallography and biophysical studies enabling ligand and degrader design

    Depositor

    Alessio Ciulli

    Article

    Kroupova et al Nat Commun. 2024 Oct 15;15(1):8885. doi:

    Insert

    CRBN (CRBN Human)
    

    Use

    Tags

    6xHis and TEV

    Expression

    Bacterial

    Mutation

    contains amino acids 41-187 followed by a Gly-Ser…

    Promoter

    lacI

    Available since

    March 26, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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17. pPHAGE_DLD-H450A-C-TAP

    Plasmid

    #83478

    Purpose

    Mammalian expression of the dehydrogenase-deficient mutant DLD-H450A.

    Depositor

    Mohan Babu

    Article

    Malty et al Cell Syst. 2017 Nov 7. pii: S2405-4712(1

    Insert

    DLD (DLD Human)
    

    Use

    Lentiviral

    Tags

    TAP

    Expression

    Mammalian

    Mutation

    H450A

    Promoter

    CMV

    Available since

    Nov. 10, 2016

    Availability

    Academic Institutions and Nonprofits only

    

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18. pPHAGE_DLD-S456A-C-TAP

    Plasmid

    #83479

    Purpose

    Mammalian expression of the proteolysis-deficient mutant DLD-S456A.

    Depositor

    Mohan Babu

    Article

    Malty et al Cell Syst. 2017 Nov 7. pii: S2405-4712(1

    Insert

    DLD (DLD Human)
    

    Use

    Lentiviral

    Tags

    TAP

    Expression

    Mammalian

    Mutation

    S456A

    Promoter

    CMV

    Available since

    Nov. 10, 2016

    Availability

    Academic Institutions and Nonprofits only

    

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19. pCR8 JARID2

    Plasmid

    #114443

    Purpose

    Entry vector for gateway cloning containing human JARID2 coding sequence

    Depositor

    Adrian Bracken

    Article

    Conway et al Mol Cell. 2018 May 3;70(3):408-421.e8. d

    Insert

    JARID2 (JARID2 Human)
    

    Use

    Gateway entry cloning

    Tags

    Expression

    Mutation

    Promoter

    None

    Available since

    Sept. 6, 2018

    Availability

    Academic Institutions and Nonprofits only

    

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20. pCDNA3.1-spikeRBD::∆ACE2 SURF

    Plasmid

    #206957

    Purpose

    Fluorescent reporter of the interaction between SARS-CoV-2 spike and human ACE2

    Depositor

    Xiaokun Shu

    Article

    Yang et al Nat Microbiol. 2023 Jan;8(1):121-134. do

    Inserts

    sars GU280_gp02, spike glycoprotein (S SARS-CoV-2)
    ACE2 (ACE2 Human)
    

    Use

    Tags

    cSURF, mCherry, and nSURF

    Expression

    Mammalian

    Mutation

    17-615 and RBD (319-541)

    Promoter

    CMV

    Available since

    Sept. 12, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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