We narrowed to 31,919 results for: Eng

1. pGL3-basic-FTO promoter_Mut

   Plasmid

   #108923

   Purpose

   The core promoter region of FTO with mutant CEBPA binding sites was inserted into pGL3 basic vector

   Depositor

   Jianjun Chen

   Article

   Su et al Cell. 2018 Jan 11;172(1-2):90-105.e23. d

   Insert

   FTO (FTO Human)
   

   Tags

   NA

   Expression

   Mammalian

   Mutation

   NA

   Available Since

   May 30, 2018

   Availability

   Academic Institutions and Nonprofits only

   

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2. pMIR-REPORT-MYC CDS_WT

   Plasmid

   #108924

   Purpose

   MYC mRNA CDS region with wild type m6A motifs was inserted into pMIR-REPORT vector

   Depositor

   Jianjun Chen

   Article

   Su et al Cell. 2018 Jan 11;172(1-2):90-105.e23. d

   Insert

   MYC (MYC Human)
   

   Expression

   Mammalian

   Promoter

   CMV

   Available Since

   May 30, 2018

   Availability

   Academic Institutions and Nonprofits only

   

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3. pCDH-3_Flag-YTHDF2-RNA-MUT

   Plasmid

   #238978

   Purpose

   Expresses the RNA-binding-deficient mutant of YTHDF2

   Depositor

   Jianjun Chen

   Article

   Chen et al Cell. 2024 Dec 12:S0092-8674(24)01324-2.

   Insert

   YTHDF2-RNA-MUT (YTHDF2 Human)
   

   Use

   Lentiviral

   Expression

   Mammalian

   Mutation

   RNA binding mutation (K416A+R527A)

   Available Since

   June 5, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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4. pCDH-3_Flag-YTHDF2-D-MUT

   Plasmid

   #238977

   Purpose

   Expresses the domain-mutant YTHDF2

   Depositor

   Jianjun Chen

   Article

   Chen et al Cell. 2024 Dec 12:S0092-8674(24)01324-2.

   Insert

   YTHDF2-D-MUT (YTHDF2 Human)
   

   Use

   Lentiviral

   Expression

   Mammalian

   Mutation

   5 site mutation (W432A+W486A+Y418A+D422A+W491A)

   Available Since

   June 5, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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5. MSCV-NRAS(G12D)-Neo

   Plasmid

   #232953

   Purpose

   Expresses mutant form of NRAS

   Depositor

   Jianjun Chen

   Article

   Chen et al Cell. 2024 Dec 12:S0092-8674(24)01324-2.

   Insert

   NRAS(G12D)-Neo (NRAS Human)
   

   Use

   Lentiviral

   Mutation

   G12D

   Available Since

   March 19, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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6. pSCBE3-NG-HF1-Hypa

   Plasmid

   #218162

   Purpose

   This plasmid harbors the base editor SCBE3-NG-HF1-Hypa along with an sgRNA cloning cassette, facilitating high-fidelity cytosine base editing at targets bearing NG PAM in Streptomyces.

   Depositor

   Yuhui Sun

   Article

   Wang et al Nat Commun. 2024 Jul 7;15(1):5687. doi:

   Inserts

   scbe3-NG-HF1-Hypa
   a programmable sgRNA cloning cassette
   

   Use

   CRISPR; Sgrna transcription

   Expression

   Bacterial

   Mutation

   Mutations in the portion of SpCas9 : D10A / N497A…

   Promoter

   rpsL promoter

   Available Since

   May 13, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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7. pJOP-HTT-HR65Q

   Plasmid

   #92249

   Purpose

   HTT donor DNA with 65Q for homologous recombination-mediated gene modification

   Depositor

   Mahmoud Pouladi

   Article

   Ooi et al Cell Rep. 2019 Feb 26;26(9):2494-2508.e7

   Insert

   HTT donor DNA (HTT Human)
   

   Use

   Precisionx hr targeting vector

   Mutation

   Barcode of wobble bases to prevent TALEN cleaving…

   Available Since

   Feb. 26, 2019

   Availability

   Academic Institutions and Nonprofits only

   

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8. pJOP-HTT-HR45Q

   Plasmid

   #92248

   Purpose

   HTT donor DNA with 45Q for homologous recombination-mediated gene modification

   Depositor

   Mahmoud Pouladi

   Article

   Ooi et al Cell Rep. 2019 Feb 26;26(9):2494-2508.e7

   Insert

   HTT donor DNA (HTT Human)
   

   Use

   Precisionx hr targeting vector

   Mutation

   Barcode of wobble bases to prevent TALEN cleaving…

   Available Since

   Feb. 26, 2019

   Availability

   Academic Institutions and Nonprofits only

   

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9. pCDH-3_Flag-YTHDF2-RNA-MUT (nonsense mutation of sgYTHDF2-1)

   Plasmid

   #232948

   Purpose

   Expresses the RNA-binding-deficient mutant of YTHDF2 with synonymous mutations for resistance against sgYTHDF2-1-mediated knockdown

   Depositor

   Jianjun Chen

   Article

   Chen et al Cell. 2024 Dec 12:S0092-8674(24)01324-2.

   Insert

   YTHDF2-RNA-MUT (YTHDF2 Human)
   

   Use

   Lentiviral

   Mutation

   RNA binding mutation (K416A+R527A), synonymous mu…

   Available Since

   May 16, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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10. pJOP-HTT-HR81Q

    Plasmid

    #92250

    Purpose

    HTT donor DNA with 81Q for homologous recombination-mediated gene modification

    Depositor

    Mahmoud Pouladi

    Article

    Ooi et al Cell Rep. 2019 Feb 26;26(9):2494-2508.e7

    Insert

    HTT donor DNA (HTT Human)
    

    Use

    Precisionx hr targeting vector

    Mutation

    Barcode of wobble bases to prevent TALEN cleaving…

    Available Since

    Feb. 26, 2019

    Availability

    Academic Institutions and Nonprofits only

    

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