Purpose
Self-amplifying RNA (saRNA) construct expresses dsRNA pathway inhibitors (E3, NSs, L*) and inflammatory signaling inhibitor, super repressor inhibitor of κBα (srIκBα).
Inserts
mScarlet3
IRES-E3-NSs-L*-EGFP
IRES-srIκBα
Use
Mouse Targeting; Self-amplifying rna
Mutation
serines 32 and 36 to alanines
Available Since
Sept. 25, 2025
Availability
Academic Institutions and Nonprofits only