We narrowed to 3,778 results for: LYC;

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pET-Impact-T4gp32(L301G)

Plasmid

#228209

Purpose

Expression in BL21(DE3) of single strand DNA binding protein L301G

Depositor

Stephen Benkovic

Insert

61

Tags

Sce VMA intein-chitin binding domain

Expression

Bacterial

Mutation

Mutated leucine 301 to glycine (L301G), improves …

Promoter

T7

Available Since

March 6, 2025

Availability

Academic Institutions and Nonprofits only

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pCMV_Myc-CylM-P2A-NLS-FLAG-YFast-TEV-His-CylLL-S15T

Plasmid

#225062

Purpose

Expression and Nuclear-localization of CylM-modified CylLL-S15T in human cells

Depositor

Wilfred van der Donk

Article

Eslami et al ACS Synth Biol. 2024 Jul 19;13(7):2128-2

Insert

CylLL-S15T

Tags

Multiple tags due to polycistronic expression

Expression

Mammalian

Mutation

S15T

Promoter

CMV

Available Since

Oct. 1, 2024

Availability

Academic Institutions and Nonprofits only

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pCMV_PML1 or 2-FLAG-YFast-TEV-6xHis-CylLL S15T-P2A-Myc-CylM

Plasmid

#225061

Purpose

Expression and Plasma membrane-localization of CylM-modified CylLL-S15T in human cells

Depositor

Wilfred van der Donk

Article

Eslami et al ACS Synth Biol. 2024 Jul 19;13(7):2128-2

Insert

CylLL-S15T

Tags

Multiple tags due to polycistronic expression

Expression

Mammalian

Mutation

S15T

Promoter

CMV

Available Since

Oct. 1, 2024

Availability

Academic Institutions and Nonprofits only

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SpyTag-RBD Delta

Plasmid

#214723

Purpose

Expresses SARS-CoV-2 Delta RBD (receptor-binding domain from Spike) with N-terminal SpyTag fusion in mammalian cells

Depositor

Mark Howarth

Article

Hills et al Nat Nanotechnol. 2024 May 6. doi: 10.103

Insert

Receptor-Binding Domain (S SARS-CoV-2)

Tags

SpyTag

Expression

Mammalian

Promoter

CMV

Available Since

June 17, 2024

Availability

Academic Institutions and Nonprofits only

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pET-29b(+)_notufA-CmEndoCOM_3C-CBD-His

Plasmid

#218198

Purpose

Bacterial expression of a His-tagged Chitin Binding fusion of Cordyceps militaris EndoCOM

Depositor

Florence Pojer

Insert

EndoCOM

Tags

3C-CBD-His

Expression

Bacterial

Mutation

codon optimized Ecoli, residues 19-315

Promoter

T7

Available Since

April 30, 2024

Availability

Academic Institutions and Nonprofits only

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B-evoSpCas9-E526K

Plasmid

#207365

Purpose

Expression plasmid for human codon-optimized increased-fidelity (i.e. high-fidelity) SpCas9 variant

Depositor

Ervin Welker

Article

Kulcsar et al Nat Commun. 2023 Sep 16;14(1):5746. doi:

Insert

B-evoSpCas9-E526K

Use

CRISPR

Tags

3xFLAG

Expression

Mammalian

Mutation

M495V, Y515N, R661Q, amino acids 1005-1013 replac…

Promoter

CBh

Available Since

Oct. 11, 2023

Availability

Academic Institutions and Nonprofits only

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B-evoSpCas9-V495M

Plasmid

#207363

Purpose

Expression plasmid for human codon-optimized increased-fidelity (i.e. high-fidelity) SpCas9 variant

Depositor

Ervin Welker

Article

Kulcsar et al Nat Commun. 2023 Sep 16;14(1):5746. doi:

Insert

B-evoSpCas9-V495M

Use

CRISPR

Tags

3xFLAG

Expression

Mammalian

Mutation

Y515N, K526E, R661Q, amino acids 1005-1013 replac…

Promoter

CBh

Available Since

Oct. 11, 2023

Availability

Academic Institutions and Nonprofits only

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186_pETcon_SARS2_XBB1-5

Plasmid

#208086

Purpose

yeast surface display of the SARS-CoV-2 XBB.1.5 variant RBD

Depositor

Tyler Starr

Article

Taylor et al PLoS Pathog. 2023 Dec 29;19(12):e1011901

Insert

SARS-CoV-2 XBB.1.5 RBD (S Budding Yeast, SARS-CoV-2 virus)

Tags

HA and c-Myc

Expression

Yeast

Available Since

Oct. 4, 2023

Availability

Academic Institutions and Nonprofits only

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B-evoSpCas9-Q661R

Plasmid

#207366

Purpose

Expression plasmid for human codon-optimized increased-fidelity (i.e. high-fidelity) SpCas9 variant

Depositor

Ervin Welker

Article

Kulcsar et al Nat Commun. 2023 Sep 16;14(1):5746. doi:

Insert

B-evoSpCas9-Q661R

Use

CRISPR

Tags

3xFLAG

Expression

Mammalian

Mutation

M495V, Y515N, K526E, amino acids 1005-1013 replac…

Promoter

CBh

Available Since

Sept. 26, 2023

Availability

Academic Institutions and Nonprofits only

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B-evoSpCas9-N515Y

Plasmid

#207364

Purpose

Expression plasmid for human codon-optimized increased-fidelity (i.e. high-fidelity) SpCas9 variant

Depositor

Ervin Welker

Article

Kulcsar et al Nat Commun. 2023 Sep 16;14(1):5746. doi:

Insert

B-evoSpCas9-N515Y

Use

CRISPR

Tags

3xFLAG

Expression

Mammalian

Mutation

M495V, K526E, R661Q, amino acids 1005-1013 replac…

Promoter

CBh

Available Since

Sept. 26, 2023

Availability

Academic Institutions and Nonprofits only

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pKG-GW2-NgBR R290H

Plasmid

#203167

Purpose

Yeast expression vector for hNUS1 R290H

Depositor

William Sessa

Article

Park et al Cell Metab. 2014 Sep 2;20(3):448-57. doi

Insert

NUS1 (NUS1 Human)

Expression

Yeast

Mutation

R290H

Promoter

TDH3

Available Since

Aug. 29, 2023

Availability

Academic Institutions and Nonprofits only

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pVRC8400-SARS-CoV-2-RBD-SD1-B.1.621-AVI

Plasmid

#181703

Purpose

Expresses SARS-CoV-2 RBD-SD1 domain from the B.1.621 variant with single chain Fc, HRV3C protease cleavage site, and AVI tag

Depositor

Peter Kwong

Article

Teng et al PLoS One. 2022 May 24;17(5):e0268767. do

Insert

SARS-CoV-2-RBD-SD1-B.1.621 (S )

Tags

AVI, HRV3C, and scFc

Expression

Mammalian

Mutation

R346K, E484K, N501Y

Available Since

March 2, 2022

Availability

Academic Institutions and Nonprofits only

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pVRC8400-SARS-CoV-2-S2P-C.37-AVI

Plasmid

#181693

Purpose

Expresses SARS-CoV-2 S2P protein from the C.37 variant with single chain Fc, HRV3C protease cleavage site, and AVI tag

Depositor

Peter Kwong

Article

Teng et al PLoS One. 2022 May 24;17(5):e0268767. do

Insert

SARS-CoV-2-S2P-C.37 (S )

Tags

AVI, HRV3C, and scFc

Expression

Mammalian

Mutation

G75V, T76I, R246N, ∆S247-∆D253, L452Q, F490S, D61…

Available Since

March 2, 2022

Availability

Academic Institutions and Nonprofits only

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pVRC8400-SARS-CoV-2-RBD-L452R-E484Q-AVI

Plasmid

#176445

Purpose

Expresses SARS-CoV-2 RBD domain containing L452R-E484Q mutations with single chain Fc, HRV3C protease cleavage site, and AVI tag

Depositor

Peter Kwong

Article

Teng et al PLoS One. 2022 May 24;17(5):e0268767. do

Insert

SARS-CoV-2-RBD-L452R-E484Q (S )

Tags

AVI, HRV3C, and scFc

Expression

Mammalian

Mutation

L452R, E484Q

Available Since

March 2, 2022

Availability

Academic Institutions and Nonprofits only

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pVRC8400-SARS-CoV-2-RBD-L452R-T478K-AVI

Plasmid

#176446

Purpose

Expresses SARS-CoV-2 RBD domain containing L452R-T478K mutations with single chain Fc, HRV3C protease cleavage site, and AVI tag

Depositor

Peter Kwong

Article

Teng et al PLoS One. 2022 May 24;17(5):e0268767. do

Insert

SARS-CoV-2-RBD-L452R-T478K (S )

Tags

AVI, HRV3C, and scFc

Expression

Mammalian

Mutation

L452R, T478K

Available Since

March 2, 2022

Availability

Academic Institutions and Nonprofits only

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pVRC8400-SARS-CoV-2-NTD-G142D-E154K-AVI

Plasmid

#176434

Purpose

Expresses SARS-CoV-2 NTD domain containing G142D-E154K mutations with single chain Fc, HRV3C protease cleavage site, and AVI tag

Depositor

Peter Kwong

Article

Teng et al PLoS One. 2022 May 24;17(5):e0268767. do

Insert

SARS-CoV-2-NTD-G142D-E154K (S )

Tags

AVI, HRV3C, and scFc

Expression

Mammalian

Mutation

G142D, E154K

Available Since

March 2, 2022

Availability

Academic Institutions and Nonprofits only

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pVRC8400-SARS-CoV-2-NTD-B.1.617.2-AVI

Plasmid

#176436

Purpose

Expresses SARS-CoV-2 NTD domain from the B.1.617.2 variant with single chain Fc, HRV3C protease cleavage site, and AVI tag

Depositor

Peter Kwong

Article

Teng et al PLoS One. 2022 May 24;17(5):e0268767. do

Insert

SARS-CoV-2-NTD-B.1.617.2 (S )

Tags

AVI, HRV3C, and scFc

Expression

Mammalian

Mutation

T19R, G142D, E156del, F157del, R158G

Available Since

March 2, 2022

Availability

Academic Institutions and Nonprofits only

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pVRC8400-SARS-CoV-2-NTD-B.1.351-AVI

Plasmid

#176426

Purpose

Expresses SARS-CoV-2 NTD domain from the B.1.351 variant with single chain Fc, HRV3C protease cleavage site, and AVI tag

Depositor

Peter Kwong

Article

Teng et al PLoS One. 2022 May 24;17(5):e0268767. do

Insert

SARS-CoV-2-NTD-B.1.351 (S )

Tags

AVI, HRV3C, and scFc

Expression

Mammalian

Mutation

L18F, D80A, D215G, 242-244del, R246I

Available Since

March 2, 2022

Availability

Academic Institutions and Nonprofits only

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pVRC8400-SARS-CoV-2-NTD-T95I-D253G-AVI

Plasmid

#176432

Purpose

Expresses SARS-CoV-2 NTD domain containing T95I-D253G mutations with single chain Fc, HRV3C protease cleavage site, and AVI tag

Depositor

Peter Kwong

Article

Teng et al PLoS One. 2022 May 24;17(5):e0268767. do

Insert

SARS-CoV-2-NTD-T95I-D253G (S )

Tags

AVI, HRV3C, and scFc

Expression

Mammalian

Mutation

T95I, D253G

Available Since

March 2, 2022

Availability

Academic Institutions and Nonprofits only

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MS2_SC2_S_Mu

Plasmid

#177366

Purpose

Generation of MS2 Virus-Like Particles packaged with the sequence for the WHO Mu SARS-CoV-2 S gene (Amino Acid 319-869)

Depositor

Paul Freemont

Inserts

Maturation Protein
Coat Protein Dimer
S gene (S SARS-CoV-2)

Expression

Bacterial

Mutation

Mu (Amino Acid 319-869)

Promoter

T7

Available Since

Jan. 20, 2022

Availability

Industry, Academic Institutions, and Nonprofits

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