We narrowed to 2,241 results for: LOB;

1. pFUSEss-CHIg-mM-Asp212Ser_M18

   Plasmid

   #91739

   Purpose

   Expression plasmid coding for mutated heavy chain of mouse IgM antibody specific to antigen B of the ABO blood group system, clone M18. Mutation: Asp212Ser (EU numbering) - N-glycosylated Asn209

   Depositor

   Joanna Bereta

   Article

   Klaus et al Sci Rep. 2018 Jan 11;8(1):519. doi: 10.1

   Insert

   immunoglobulin heavy constant mu (Ighm Mouse)
   

   Use

   Tags

   Expression

   Mammalian

   Mutation

   Asp212 changed to Ser (EU numbering)

   Promoter

   hEF1-HTLV prom

   Available since

   June 12, 2017

   Availability

   Academic Institutions and Nonprofits only

   

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2. pIS1 mEPAS1

   Plasmid

   #60793

   Purpose

   Luciferase reporter to measure miR-155 mediated differential repression. Contains EPAS1 3' UTR and mutated miR-155 sites

   Depositor

   David Bartel

   Article

   Nam et al Mol Cell. 2014 Mar 20;53(6):1031-43. doi

   Insert

   EPAS1 3'UTR and mutated miR-155 binding site (EPAS1 Human)
   

   Use

   Luciferase

   Tags

   Expression

   Mammalian

   Mutation

   mutated miR-155 binding site

   Promoter

   thymidine kinase (HSV-TK promoter)

   Available since

   May 18, 2015

   Availability

   Academic Institutions and Nonprofits only

   

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3. LVXN-Neo-NSD2

   Plasmid

   #86010

   Purpose

   express wild-type NSD2 in mammalian cells

   Depositor

   Darrin Stuart

   Article

   Jaffe et al Nat Genet. 2013 Nov;45(11):1386-91. doi:

   Insert

   NSD2 (NSD2 Human)
   

   Use

   Lentiviral

   Tags

   Flag tag D Y K D D D D K

   Expression

   Bacterial

   Mutation

   K1002R (please see depositor comments below)

   Promoter

   CMV

   Available since

   Jan. 11, 2017

   Availability

   Academic Institutions and Nonprofits only

   

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4. pYX233-b2delta-DHFR

   Plasmid

   #163760

   Purpose

   Gal-inducible yeast expression of the mitochondrial "clogger" protein b2(167)delta(19)-DHFR

   Depositor

   Johannes Herrmann

   Article

   Boos et al Nat Cell Biol. 2019 Apr;21(4):442-451. d

   Insert

   b2delta-DHFR (Dhfr Mouse, Budding Yeast)
   

   Use

   Tags

   Expression

   Yeast

   Mutation

   Amino acids 1-167 of S.c. Cytochrome b2 (Cyb2) fu…

   Promoter

   GAL1

   Available since

   Jan. 13, 2021

   Availability

   Academic Institutions and Nonprofits only

   

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5. Human/mouse ELL2

   Plasmid

   #127254

   Purpose

   Expresses a human/mouse chimera that increases ELL2 expression in mammalian cells

   Depositor

   Christine Milcarek

   Article

   Martincic et al Nat Immunol. 2009 Oct;10(10):1102-9. doi

   Insert

   N-terminal human/C-terminal mouse ELL2 (ELL2, Ell2 Mouse, Human)
   

   Use

   Other

   Tags

   His6X

   Expression

   Mammalian

   Mutation

   N terminal amino acids (1-287) are human, C termi…

   Promoter

   pEF1a

   Available since

   Aug. 7, 2019

   Availability

   Academic Institutions and Nonprofits only

   

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6. LVXN-Neo-NSD2-E1099K

   Plasmid

   #86011

   Purpose

   express NSD2 E1099K mutant in mammalian cells

   Depositor

   Darrin Stuart

   Article

   Jaffe et al Nat Genet. 2013 Nov;45(11):1386-91. doi:

   Insert

   NSD2 E1099K mutant (NSD2 Human)
   

   Use

   Tags

   Flag tag  D Y K D D D D K

   Expression

   Mammalian

   Mutation

   E1099K; K1002R (please see depositor comments bel…

   Promoter

   CMV

   Available since

   Jan. 13, 2017

   Availability

   Academic Institutions and Nonprofits only

7. AiP12251-pAAV-AiE0453m-minBG-SYFP2-WPRE3-BGHpA (Alias: CN2251)

   Plasmid

   #164453

   Purpose

   AiE0453m is an enhancer sequence designed to drive AAV-mediated transgene expression in L5_ET cortical neurons

   Depositor

   The Allen Institute for Brain Science, Jonathan Ting

   Article

   Graybuck et al Neuron. 2021 Mar 23. pii: S0896-6273(21)

   Insert

   SYFP2
   

   Use

   AAV

   Tags

   Expression

   Mutation

   Promoter

   minBetaGlobin

   Available since

   Feb. 25, 2021

   Availability

   Academic Institutions and Nonprofits only

   

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8. pEN435 - pCAGGS-TagBFP-hGeminin-2A-mCherry-hCdt1-rbgpA-Frt-PGK-EM7-PuroR-bpA-Frt Tigre targeting

   Plasmid

   #92139

   Purpose

   Targeting vector to introduce a Fucci cell cyle reporter cassette mCherry(G1)/BFP(S/G2) at the mouse TIGRE acceptor locus using puromycin selection

   Depositor

   Benoit Bruneau

   Article

   Nora et al Cell. 2017 May 18;169(5):930-944.e22. do

   Insert

   chromatin licensing and DNA replication factor 1 (GMNN, CDT1 Human)
   

   Use

   Mouse Targeting

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   Available since

   June 27, 2017

   Availability

   Academic Institutions and Nonprofits only

   

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9. pQ-Elo-HB-C-A(1-630)

   Plasmid

   #171086

   Purpose

   Co-expresses of ΔC-ELOA containing Elongin complex in bacteria. The resulting plasmid was used to generate a single expression construct encoding all 3Elongin subunits, with a 6-His tag on ELOB

   Depositor

   Joan Conaway

   Article

   He et al Proc Natl Acad Sci U S A. 2021 Sep 28;11

   Inserts

   Elongin B (ELOB Human)
   Elongin C (ELOC Human)
   Elongin A (ELOA Human)
   

   Use

   Tags

   His

   Expression

   Bacterial

   Mutation

   Deleted N-term 26aa and C-term 142aa for mutant e…

   Promoter

   T5 promoter

   Available since

   July 19, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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10. pET21b(+)_SARS-CoV-2_3CLpro-Q306A

    Plasmid

    #177334

    Purpose

    bacterial expression of active SARS-CoV-2 3C-like proteinase

    Depositor

    Christopher Overall

    Article

    Pablos et al Cell Rep. 2021 Oct 26;37(4):109892. doi:

    Insert

    SARS-CoV-2 3C-like proteinase (ORF1ab Severe acute respiratory syndrome coronavirus 2) (ORF1ab SARS-CoV-2 virus)
    

    Use

    Tags

    Factor Xa site-3xFlag-Myc-6xHis

    Expression

    Bacterial

    Mutation

    silent mutation C to T at position 10546 (elimina…

    Promoter

    T7

    Available since

    Nov. 23, 2021

    Availability

    Industry, Academic Institutions, and Nonprofits

    

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