We narrowed to 13,238 results for: BASE

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pBM13h-sd4U

Plasmid

#179690

Purpose

Bacterial expression of base editor

Depositor

David Liu

Article

Mok et al Nat Biotechnol. 2022 Sep;40(9):1378-1387

Insert

[sd4U] UGI-TALE3-DddA-G1397-N wildtype

Expression

Bacterial

Available Since

April 4, 2022

Availability

Academic Institutions and Nonprofits only

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pAT9753-BEAR-mScarlet-preedited

Plasmid

#162994

Purpose

BEAR control plasmid with split mScarlet and intact 5' splice site

Depositor

Ervin Welker

Article

Talas et al Nat Commun. 2021 Nov 3;12(1):6353. doi:

Insert

mScarlet split with an intron between amino acids 110-111

Use

CRISPR

Expression

Mammalian

Promoter

CMV

Available Since

Sept. 21, 2021

Availability

Academic Institutions and Nonprofits only

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pDM_noro_A1_lacZA

Plasmid

#118818

Purpose

T7 RNAP-driven expression of norovirus antisense orientation toehold switches (A1) with a lacZ alpha subunit reporter.

Depositor

Alexander Green

Article

Ma et al Synth Biol (Oxf). 2018;3(1):ysy018. doi:

Insert

Norovirus toehold switch A1

Expression

Bacterial

Available Since

Jan. 27, 2021

Availability

Academic Institutions and Nonprofits only

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pJRK248

Plasmid

#173755

Purpose

co-injection plasmid

Depositor

Mike Boxem

Article

Kroll et al Genetics. 2021 Dec 10;219(4). pii: 63804

Insert

Prps-0::HygR::unc-54 3'UTR; Psqt-1::sqt-1::sqt-1 3' UTR

Expression

Worm

Available Since

Sept. 14, 2021

Availability

Academic Institutions and Nonprofits only

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pAAV-CASI-InteinC-SpG C aa714-1368-U6-Lmna sgRNA1

Plasmid

#208110

Purpose

Expresses SpG cas9C by the constitutive CASI promoter and sgRNA targeting murine Lmna c.1621T mutation by U6 promoter

Depositor

Yuxuan Guo

Article

Yang et al J Cell Mol Med. 2024 Feb;28(4):e18145. d

Insert

SpG C, U6, Lmna sgRNA1, scaffold

Use

AAV

Promoter

U6

Available Since

Feb. 13, 2024

Availability

Academic Institutions and Nonprofits only

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pAAV-CASI-inteinC-aa713 SpG C-U6- sgRNA scaffold

Plasmid

#208111

Purpose

Expresses SpG cas9C by the constitutive CASI promoter and sgRNA scaffold by U6 promoter

Depositor

Yuxuan Guo

Article

Yang et al J Cell Mol Med. 2024 Feb;28(4):e18145. d

Insert

SpG C, U6, scaffold

Use

AAV

Available Since

Feb. 13, 2024

Availability

Academic Institutions and Nonprofits only

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pAAV-CMV-TadA7.10-SpG N aa2-713-InteinN

Plasmid

#206967

Purpose

Expresses TadA7.10 and SpG cas9N by the constitutive CMV promoter

Depositor

Yuxuan Guo

Article

Yang et al J Cell Mol Med. 2024 Feb;28(4):e18145. d

Insert

CMV, TadA7.10, SpG N

Use

AAV

Promoter

CMV

Available Since

Feb. 13, 2024

Availability

Academic Institutions and Nonprofits only

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pAAV-CMV-TadA8e-SpG N aa2-713-InteinN

Plasmid

#206968

Purpose

Expresses TadA8e and SpG cas9N by the constitutive CMV promoter

Depositor

Yuxuan Guo

Article

Yang et al J Cell Mol Med. 2024 Feb;28(4):e18145. d

Insert

CMV, TadA8e, SpG N

Use

AAV

Available Since

Feb. 13, 2024

Availability

Academic Institutions and Nonprofits only

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pAAV-CASI-InteinC-NG C aa714-1368-U6-Lmna sgRNA1

Plasmid

#206974

Purpose

Expresses NG cas9C by the constitutive CASI promoter and sgRNA targeting murine Lmna c.1621T mutation by U6 promoter

Depositor

Yuxuan Guo

Article

Yang et al J Cell Mol Med. 2024 Feb;28(4):e18145. d

Insert

NG aa714-1368, U6, Lmna sgRNA1

Use

AAV

Promoter

U6

Available Since

Feb. 13, 2024

Availability

Academic Institutions and Nonprofits only

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pAAV-EFS-TadA8e-Sauri-U6-Lmna sgRNA

Plasmid

#206979

Purpose

Expresses SauriABE8e by EFS promoter and sgRNA targeting murine Lmna c.1621T mutation by U6 promoter

Depositor

Yuxuan Guo

Article

Yang et al J Cell Mol Med. 2024 Feb;28(4):e18145. d

Insert

Lmna sgRNA

Use

AAV; Adenine base editor

Promoter

U6

Available Since

Feb. 13, 2024

Availability

Academic Institutions and Nonprofits only

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pACBE-ASR (pXK-607)

Plasmid

#208822

Purpose

Universal Antibiotic Screening Reporter for adenine and cytosine base editors. Key Construct: CMV-PuroR*(ATAACG)-eGFP-hU6-gRNA.

Depositor

Kun Xu

Article

Ma et al J Biol Chem. 2022 Jul;298(7):102103. doi

Type

Empty backbone

Tags

EGFP

Expression

Mammalian

Promoter

CMV, U6

Available Since

Dec. 14, 2023

Availability

Academic Institutions and Nonprofits only

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pACBE-FSR (pXK-1648)

Plasmid

#208821

Purpose

Universal Fluorescent Surrogate Reporter for adenine and cytosine base editors. Key Construct: CMV-mCherry-CMV-eGFP* (ATAACG)-hU6-gRNA.

Depositor

Kun Xu

Article

Ma et al J Biol Chem. 2022 Jul;298(7):102103. doi

Type

Empty backbone

Tags

EGFP

Expression

Mammalian

Promoter

CMV, U6

Available Since

Dec. 14, 2023

Availability

Academic Institutions and Nonprofits only

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A3Bctd-L7G-Cas9n-UGI-NLS

Plasmid

#198886

Purpose

Express A3Bctd-L7G BE3-based base editor

Depositor

Reuben Harris

Article

Rieffer et al CRISPR J. 2023 Oct;6(5):430-446. doi: 10

Insert

Apolipoprotein B mRNA Editing Enzyme, Catalytic Polypeptide-like 3B C-terminal domain (APOBEC3B Human)

Tags

NLS

Expression

Mammalian

Mutation

Loop 7 of A3G

Promoter

CMV

Available Since

Nov. 6, 2023

Availability

Academic Institutions and Nonprofits only

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A3Bctd-D314E-Cas9n-UGI-NLS

Plasmid

#198887

Purpose

Express A3Bctd-D314E BE3-based base editor

Depositor

Reuben Harris

Article

Rieffer et al CRISPR J. 2023 Oct;6(5):430-446. doi: 10

Insert

Apolipoprotein B mRNA Editing Enzyme, Catalytic Polypeptide-like 3B C-terminal domain (APOBEC3B Human)

Tags

NLS

Expression

Mammalian

Mutation

D314E

Promoter

CMV

Available Since

Nov. 6, 2023

Availability

Academic Institutions and Nonprofits only

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A3Bctd-max

Plasmid

#198888

Purpose

Express A3Bctd-max BE4max-based base editor

Depositor

Reuben Harris

Article

Rieffer et al CRISPR J. 2023 Oct;6(5):430-446. doi: 10

Insert

Apolipoprotein B mRNA Editing Enzyme, Catalytic Polypeptide-like 3B C-terminal domain (APOBEC3B Human)

Tags

6x His and NLS

Expression

Mammalian

Promoter

CMV

Available Since

Nov. 6, 2023

Availability

Academic Institutions and Nonprofits only

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pLKO.1-puro-PARG shRNA

Plasmid

#23260

Depositor

Robert Sobol

Article

Tang et al Mol Cancer Res. 2010 Jan;8(1):67-79. doi

Insert

poly(ADP-ribose) glycohydrolase shRNA

Use

Lentiviral and RNAi

Expression

Mammalian

Available Since

March 31, 2010

Availability

Academic Institutions and Nonprofits only
pCMV-ABEmax(TadA E59Q, TadA* V106W)

Plasmid

#126496

Purpose

Expresses ABEmax(TadA E59Q, TadA*V106W) in mammalian cells

Depositor

David Liu

Article

Rees et al Sci Adv. 2019 May 8;5(5):eaax5717. doi:

Insert

ABEmax(TadA E59Q TadA* V106W)

Expression

Mammalian

Available Since

May 25, 2021

Availability

Academic Institutions and Nonprofits only

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pCMV-ABEmax(TadA E59, TadA* V106W)

Plasmid

#126497

Purpose

Expresses ABEmax(TadA E59, TadA*V106W) in mammalian cells

Depositor

David Liu

Article

Rees et al Sci Adv. 2019 May 8;5(5):eaax5717. doi:

Insert

ABEmax(TadA E59 TadA* V106W)

Expression

Mammalian

Available Since

May 25, 2021

Availability

Academic Institutions and Nonprofits only

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pCMV-ABEmax(TadA E59A, TadA*R47W)

Plasmid

#125659

Purpose

pCMV-ABEmax(TadA E59A, TadA*R47W) in mammalian cells

Depositor

David Liu

Article

Rees et al Sci Adv. 2019 May 8;5(5):eaax5717. doi:

Insert

ABEmax(TadA E59A TadA* R47W)

Expression

Mammalian

Available Since

June 6, 2019

Availability

Academic Institutions and Nonprofits only

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pCMV-ABEmax(TadA E59A, TadA*R47M)

Plasmid

#125660

Purpose

pCMV-ABEmax(TadA E59A, TadA*R47M) in mammalian cells

Depositor

David Liu

Article

Rees et al Sci Adv. 2019 May 8;5(5):eaax5717. doi:

Insert

ABEmax(TadA E59A TadA* R47M)

Expression

Mammalian

Available Since

June 6, 2019

Availability

Academic Institutions and Nonprofits only

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