We narrowed to 15,826 results for: grna

1. Px458-Cas9n-Trp73-Exon4-4sgRNA

   Plasmid

   #88851

   Purpose

   CRISPR KO of Trp73

   Depositor

   Joan Massague

   Article

   Wang et al Cell Stem Cell. 2017 Jan 5;20(1):70-86.

   Insert

   Trp73 (Trp73 Mouse)
   

   Use

   CRISPR

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   Available Since

   July 11, 2017

   Availability

   Academic Institutions and Nonprofits only

2. non-targeting control gRNA (BRDN0001147095)

   Plasmid

   #80222

   Purpose

   3rd generation lentiviral gRNA plasmid, non-targeting control gRNA

   Depositor

   John Doench, David Root

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Insert

   Non-targeting control gRNA
   

   Use

   CRISPR and Lentiviral

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   hU6

   Available Since

   Aug. 30, 2016

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

3. non-targeting control gRNA (BRDN0001162447)

   Plasmid

   #80239

   Purpose

   3rd generation lentiviral gRNA plasmid, non-targeting control gRNA

   Depositor

   John Doench, David Root

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Insert

   Non-targeting control gRNA
   

   Use

   CRISPR and Lentiviral

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   hU6

   Available Since

   Aug. 30, 2016

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

4. non-targeting control gRNA (BRDN0001146327)

   Plasmid

   #80188

   Purpose

   3rd generation lentiviral gRNA plasmid, non-targeting control gRNA

   Depositor

   John Doench, David Root

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Insert

   Non-targeting control gRNA
   

   Use

   CRISPR and Lentiviral

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   hU6

   Available Since

   Aug. 30, 2016

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

5. pMD19T-slr0230-PL31-sgRNANT1-KmR

   Plasmid

   #73221

   Purpose

   Contains sgRNA which targets GFPmut3b. Under an aTc inducible promoter. Suicide vector inserts into slr0230 site of Synechocystis. Carries kanamycin resistance. Propogates in E. coli

   Depositor

   Paul Hudson

   Article

   Yao et al ACS Synth Biol. 2015 Dec 28.

   Insert

   PL31-sgRNA NT1
   

   Use

   Tags

   Expression

   Bacterial

   Mutation

   Promoter

   PL31

   Available Since

   Feb. 23, 2016

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

6. pLKO.1-puro U6 sgRNA SOX17 -296

   Plasmid

   #50926

   Purpose

   U6 driven sgRNA targeting Sox17 -296 bp from TSS

   Depositor

   Rene Maehr, Scot Wolfe

   Article

   Kearns et al Development. 2014 Jan;141(1):219-23. doi

   Insert

   Sox17-296 sgRNA (SOX17 Human)
   

   Use

   CRISPR and Lentiviral

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   U6

   Available Since

   Jan. 22, 2014

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

7. pBR322-sgRNA-pvc18-20-Pdp1_NTD-Cre

   Plasmid

   #243748

   Purpose

   PVC cargo/regulatory region - deleted toxin cargos (Pdp1/Pnf) - vegfa sgRNA - Cre loaded into the PVC tube via Pdp1 (NTD)

   Depositor

   Feng Zhang

   Article

   Kreitz et al Nat Biotechnol. 2025 Aug 12. doi: 10.103

   Insert

   vegfa sgRNA-pvc18-20-Pdp1_NTD-Cre
   

   Use

   Tags

   Expression

   Bacterial

   Mutation

   Promoter

   Available Since

   Sept. 24, 2025

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

8. AgU6.695_3xP3-DsRed1-SV40 (Single gRNA)

   Plasmid

   #243009

   Purpose

   For cloning a single gRNA after BspQI digestion under An. gambiae U6.695 promoter.

   Depositor

   George Christophides

   Type

   Empty backbone

   Use

   CRISPR and Synthetic Biology

   Tags

   Expression

   Insect

   Mutation

   Promoter

   Available Since

   Sept. 19, 2025

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

9. pU6 pegRNA ROSA 4b PhiC31 attP41

   Plasmid

   #242881

   Purpose

   Mammalian expression of epegRNA for twin prime editing of half the minimal PhiC31 attP site targeting the human ROSA26 site

   Depositor

   Jesse Owens

   Article

   Hew et al Nucleic Acids Res. 2024 Jul 2:gkae534. d

   Insert

   epegRNA for PhiC31 attP site
   

   Use

   Tags

   Expression

   Mammalian

   Mutation

   none

   Promoter

   U6

   Available Since

   Sept. 16, 2025

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

10. pU6 pegRNA AAV 4a PhiC31 attP41

    Plasmid

    #242882

    Purpose

    Mammalian expression of epegRNA for twin prime editing of half the minimal PhiC31 attP site targeting the human AAVS1 site

    Depositor

    Jesse Owens

    Article

    Hew et al Nucleic Acids Res. 2024 Jul 2:gkae534. d

    Insert

    epegRNA for PhiC31 attP site
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    none

    Promoter

    U6

    Available Since

    Sept. 16, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

11. pU6 pegRNA AAV 3b PhiC31 attP41

    Plasmid

    #242883

    Purpose

    Mammalian expression of epegRNA for twin prime editing of half the minimal PhiC31 attP site targeting the human AAVS1 site

    Depositor

    Jesse Owens

    Article

    Hew et al Nucleic Acids Res. 2024 Jul 2:gkae534. d

    Insert

    epegRNA for PhiC31 attP site
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    none

    Promoter

    U6

    Available Since

    Sept. 16, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

12. pU6 pegRNA ROSA 4b Bxb1 attB38

    Plasmid

    #242879

    Purpose

    Mammalian expression of epegRNA for twin prime editing of half the minimal Bxb1 attB site targeting the human ROSA26 site

    Depositor

    Jesse Owens

    Article

    Hew et al Nucleic Acids Res. 2024 Jul 2:gkae534. d

    Insert

    epegRNA for Bxb1 attB site
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    none

    Promoter

    U6

    Available Since

    Sept. 16, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

13. pU6 pegRNA ROSA 4a Bxb1 attB38

    Plasmid

    #242878

    Purpose

    Mammalian expression of epegRNA for twin prime editing of half the minimal Bxb1 attB site targeting the human ROSA26 site

    Depositor

    Jesse Owens

    Article

    Hew et al Nucleic Acids Res. 2024 Jul 2:gkae534. d

    Insert

    epegRNA for Bxb1 attB site
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    none

    Promoter

    U6

    Available Since

    Sept. 16, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

14. pU6 pegRNA ROSA 4a PhiC31 attP41

    Plasmid

    #242880

    Purpose

    Mammalian expression of epegRNA for twin prime editing of half the minimal PhiC31 attP site targeting the human ROSA26 site

    Depositor

    Jesse Owens

    Article

    Hew et al Nucleic Acids Res. 2024 Jul 2:gkae534. d

    Insert

    epegRNA for PhiC31 attP site
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    none

    Promoter

    U6

    Available Since

    Sept. 16, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

15. pLenti-U6-epegRNA eBAR3-SV40-puro

    Plasmid

    #240537

    Purpose

    Lentiviral eBAR3 backbone plasmid to insert epegRNAs (tevopreq1) of interest with puromycin resistance. The cloning site is BsmBI.

    Depositor

    Wensheng Wei

    Article

    Niu et al Nat Biotechnol. 2025 Jun 24. doi: 10.103

    Insert

    epegRNA-eBAR3
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Available Since

    Sept. 16, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

16. pLenti-U6-epegRNA eBAR2-SV40-puro

    Plasmid

    #240536

    Purpose

    Lentiviral eBAR2 backbone plasmid to insert epegRNAs (tevopreq1) of interest with puromycin resistance. The cloning site is BsmBI.

    Depositor

    Wensheng Wei

    Article

    Niu et al Nat Biotechnol. 2025 Jun 24. doi: 10.103

    Insert

    epegRNA-eBAR2
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Available Since

    Sept. 16, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

17. LentiCRISPR-B_sgRNA_EXOSC6 (pP18(T)_B11-AVA4069)

    Plasmid

    #239304

    Purpose

    Lentiviral vector expressing Cas9-P2A-Blasticidin and an sgRNA targeting EXOSC6

    Depositor

    Andrei Alexandrov

    Article

    Che et al Nat Commun. 2025 May 22;16(1):4741. doi:

    Insert

    U6-driven sgRNA targeting EXOSC6 (EXOSC6 Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mutation

    Promoter

    Available Since

    Aug. 4, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

18. LentiCRISPR-B_sgRNA_EXOSC7 (pP18(T)_C4-AVA4066)

    Plasmid

    #239305

    Purpose

    Lentiviral vector expressing Cas9-P2A-Blasticidin and an sgRNA targeting EXOSC7

    Depositor

    Andrei Alexandrov

    Article

    Che et al Nat Commun. 2025 May 22;16(1):4741. doi:

    Insert

    U6-driven sgRNA targeting EXOSC7 (EXOSC7 Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mutation

    Promoter

    Available Since

    Aug. 4, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

19. LentiCRISPR-B_sgRNA_EXOSC8 (pP18(T)_B1-AVA4071)

    Plasmid

    #239306

    Purpose

    Lentiviral vector expressing Cas9-P2A-Blasticidin and an sgRNA targeting EXOSC8

    Depositor

    Andrei Alexandrov

    Article

    Che et al Nat Commun. 2025 May 22;16(1):4741. doi:

    Insert

    U6-driven sgRNA targeting EXOSC8 (EXOSC8 Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mutation

    Promoter

    Available Since

    Aug. 4, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

20. LentiCRISPR-B_sgRNA_EXOSC9 (pP18(T)_A7-AVA4072)

    Plasmid

    #239307

    Purpose

    Lentiviral vector expressing Cas9-P2A-Blasticidin and an sgRNA targeting EXOSC9

    Depositor

    Andrei Alexandrov

    Article

    Che et al Nat Commun. 2025 May 22;16(1):4741. doi:

    Insert

    U6-driven sgRNA targeting EXOSC9 (EXOSC9 Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mutation

    Promoter

    Available Since

    Aug. 4, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

21. LentiCRISPR-B_sgRNA_DIS3 (pP18(T)_A5-AVA4073)

    Plasmid

    #239308

    Purpose

    Lentiviral vector expressing Cas9-P2A-Blasticidin and an sgRNA targeting DIS3

    Depositor

    Andrei Alexandrov

    Article

    Che et al Nat Commun. 2025 May 22;16(1):4741. doi:

    Insert

    U6-driven sgRNA targeting DIS3 (DIS3 Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mutation

    Promoter

    Available Since

    Aug. 4, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

22. LentiCRISPR-B_sgRNA_C1D (pP18(T)_B9-AVA4070)

    Plasmid

    #239296

    Purpose

    Lentiviral vector expressing Cas9-P2A-Blasticidin and an sgRNA targeting C1D

    Depositor

    Andrei Alexandrov

    Article

    Che et al Nat Commun. 2025 May 22;16(1):4741. doi:

    Insert

    U6-driven sgRNA targeting C1D (C1D Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mutation

    Promoter

    Available Since

    Aug. 4, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

23. LentiCRISPR-B_sgRNA_EXOSC2 (pP18(T)_C3-AVA4067)

    Plasmid

    #239301

    Purpose

    Lentiviral vector expressing Cas9-P2A-Blasticidin and an sgRNA targeting EXOSC2

    Depositor

    Andrei Alexandrov

    Article

    Che et al Nat Commun. 2025 May 22;16(1):4741. doi:

    Insert

    U6-driven sgRNA targeting EXOSC2 (EXOSC2 Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mutation

    Promoter

    Available Since

    Aug. 4, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

24. LentiCRISPR-B_sgRNA_EXOSC4 (pP18(T)_C11-AVA4065)

    Plasmid

    #239302

    Purpose

    Lentiviral vector expressing Cas9-P2A-Blasticidin and an sgRNA targeting EXOSC4

    Depositor

    Andrei Alexandrov

    Article

    Che et al Nat Commun. 2025 May 22;16(1):4741. doi:

    Insert

    U6-driven sgRNA targeting EXOSC4 (EXOSC4 Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mutation

    Promoter

    Available Since

    Aug. 4, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

25. LentiCRISPR-B_sgRNA_EXOSC5 (pP18(T)_B12-AVA4068)

    Plasmid

    #239303

    Purpose

    Lentiviral vector expressing Cas9-P2A-Blasticidin and an sgRNA targeting EXOSC5

    Depositor

    Andrei Alexandrov

    Article

    Che et al Nat Commun. 2025 May 22;16(1):4741. doi:

    Insert

    U6-driven sgRNA targeting EXOSC5 (EXOSC5 Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mutation

    Promoter

    Available Since

    Aug. 4, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

26. lentiCRISPRv2-bleo-Merlin(dog)gRNA2

    Plasmid

    #214824

    Purpose

    A knockout vector for dog Merlin.

    Depositor

    Michiyuki Matsuda

    Article

    Jikko et al J Cell Sci. 2025 Jul 16:jcs.263779. doi:

    Insert

    A gRNA targeting the dog NF2(Merlin) gene and the cDNA of CRISPR-Cas9
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Available Since

    July 22, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

27. AAV-pCamKII-Cre-pU6-SpCas9gRNAentry

    Plasmid

    #210391

    Purpose

    AAV plasmid encoding the CamKII promoter driving Cre expression, along with SpCas9 gRNA entry cassette (RFP dropout)

    Depositor

    Benjamin Kleinstiver

    Article

    Huynh et al Nature. 2024 Nov;635(8037):168-177. doi:

    Insert

    AAV-(ITR)-pCamKII-NLS-Cre-WPRE-bGHpA-(rev)-SpCas9_gRNA-BsmBI_RFPcassette-hU6-(ITR) (NJA158)
    

    Use

    AAV and CRISPR

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    CamKII promoter for Cre, human U6 promoter for Sp…

    Available Since

    July 2, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

28. sgPlxnb2-2 in pT4-U6-sgRNA-CMV-EGFP

    Plasmid

    #239589

    Purpose

    expresses guide#2 to boost the expression of mouse Plxnb2, via CRISPRa

    Depositor

    Andreas Moor

    Article

    Borrelli et al Nature. 2024 Aug;632(8024):411-418. doi:

    Insert

    sgRNA targeting TSS-upstream reagion of Plxnb2 (Plxnb2 Mouse)
    

    Use

    Sleeping beauty (sb) transposon

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    hU6

    Available Since

    June 18, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

29. sgPlxnb2-3 in pT4-U6-sgRNA-CMV-EGFP

    Plasmid

    #239590

    Purpose

    expresses guide#3 to boost the expression of mouse Plxnb2, via CRISPRa

    Depositor

    Andreas Moor

    Article

    Borrelli et al Nature. 2024 Aug;632(8024):411-418. doi:

    Insert

    sgRNA targeting TSS-upstream reagion of Plxnb2 (Plxnb2 Mouse)
    

    Use

    Sleeping beauty (sb) transposon

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    hU6

    Available Since

    June 18, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

30. sgPlxnb2-1 in pT4-U6-sgRNA-CMV-EGFP

    Plasmid

    #239588

    Purpose

    expresses guide#1 to boost the expression of mouse Plxnb2, via CRISPRa

    Depositor

    Andreas Moor

    Article

    Borrelli et al Nature. 2024 Aug;632(8024):411-418. doi:

    Insert

    sgRNA targeting TSS-upstream reagion of Plxnb2 (Plxnb2 Mouse)
    

    Use

    Sleeping beauty (sb) transposon

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    hU6

    Available Since

    June 12, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge