We narrowed to 2,383 results for: neurod

1. pU6-crRNA(TARDBP)

   Plasmid

   #109323

   Purpose

   AAV vector expressing crRNA for AsCpf1 (RR variant) targeting human TARDBP

   Depositor

   Feng Zhang

   Article

   Tekin et al Nat Biomed Eng. 2018 Jul;2(7):540-554. d

   Insert

   mCherry-KASH (TARDBP Human)
   

   Use

   AAV

   Tags

   Expression

   Mutation

   Promoter

   hSyn1

   Available since

   April 30, 2018

   Availability

   Academic Institutions and Nonprofits only

   

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2. PINK1 gRNA (BRDN0001144744)

   Plasmid

   #78038

   Purpose

   3rd generation lentiviral gRNA plasmid targeting human PINK1

   Depositor

   David Root, John Doench

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Insert

   PINK1 (PINK1 Human)
   

   Use

   CRISPR and Lentiviral

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   hU6

   Available since

   July 6, 2016

   Availability

   Academic Institutions and Nonprofits only

   

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3. pTWIN1-His6-Ssp-Htt2-90-43Q-P90C

   Plasmid

   #114626

   Purpose

   Bacterial expression of Htt fragment containing amino acids 2-90, with P90C cysteine mutation and a 43 polyQ repeat

   Depositor

   Hilal Lashuel

   Article

   Warner JB et al J Am Chem Soc. 2017 Oct 18;139(41):14456

   Insert

   Huntingtin Exon1 fragment (HTT Human)
   

   Use

   Tags

   His6-Ssp DnaB intein

   Expression

   Bacterial

   Mutation

   P90C; 43 polyQ repeat

   Promoter

   Available since

   Sept. 19, 2018

   Availability

   Academic Institutions and Nonprofits only

   

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4. pTWIN1-His6-Ssp-Htt2-90-15Q-P90C

   Plasmid

   #114611

   Purpose

   Bacterial expression of Htt fragment containing amino acids 2-90, with P90C cysteine mutation and a 15 polyQ repeat

   Depositor

   Hilal Lashuel

   Article

   Warner JB et al J Am Chem Soc. 2017 Oct 18;139(41):14456

   Insert

   Huntingtin Exon1 fragment (HTT Human)
   

   Use

   Tags

   His6-Ssp DnaB intein

   Expression

   Bacterial

   Mutation

   P90C; 23 polyQ repeat

   Promoter

   Available since

   Sept. 18, 2018

   Availability

   Academic Institutions and Nonprofits only

   

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5. MLM3636-Prnp-CDS-Pos

   Plasmid

   #61857

   Purpose

   Expresses a gRNA plasmid targeting the prion gene's exon 3, positive strand

   Depositor

   Gerold Schmitt-Ulms

   Article

   Mehrabian et al PLoS One. 2014 Dec 9;9(12):e114594. doi:

   Insert

   PrP guiding sequence (Prnp Mouse)
   

   Use

   CRISPR

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   hU6 promoter

   Available since

   Feb. 3, 2015

   Availability

   Academic Institutions and Nonprofits only

6. MLM3636-Prnp-CDS-Neg

   Plasmid

   #61856

   Purpose

   Expresses a gRNA plasmid targeting the prion gene's exon 3, negative strand

   Depositor

   Gerold Schmitt-Ulms

   Article

   Mehrabian et al PLoS One. 2014 Dec 9;9(12):e114594. doi:

   Insert

   PrP guiding sequence (Prnp Mouse)
   

   Use

   CRISPR

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   hU6 promoter

   Available since

   Feb. 3, 2015

   Availability

   Academic Institutions and Nonprofits only

7. pTWIN1-His6-Ssp-Htt2-90(A2C)-37Q

   Plasmid

   #114617

   Purpose

   Bacterial expression of Htt fragment containing amino acids 2-90, with A2C cysteine mutation and a 37 polyQ repeat

   Depositor

   Hilal Lashuel

   Article

   Warner JB et al J Am Chem Soc. 2017 Oct 18;139(41):14456

   Insert

   Huntingtin Exon1 fragment (HTT Human)
   

   Use

   Tags

   His6-Ssp DnaB intein

   Expression

   Bacterial

   Mutation

   A2C; 23 polyQ repeat

   Promoter

   Available since

   Oct. 5, 2018

   Availability

   Academic Institutions and Nonprofits only

   

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8. pTWIN1-His6-Ssp-Httex1-43Q-A2C

   Plasmid

   #114622

   Purpose

   Bacterial expression of Htt fragment containing exon 1, with A2C cysteine mutation and a 43 polyQ repeat

   Depositor

   Hilal Lashuel

   Article

   Warner JB et al J Am Chem Soc. 2017 Oct 18;139(41):14456

   Insert

   Huntingtin Exon1 (HTT Human)
   

   Use

   Tags

   His6-Ssp DnaB intein

   Expression

   Bacterial

   Mutation

   A2C; 43 polyQ repeat

   Promoter

   Available since

   Sept. 18, 2018

   Availability

   Academic Institutions and Nonprofits only

   

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9. pTWIN1-His6-Ssp-Httex1-43Q-A2C-A60C

   Plasmid

   #114623

   Purpose

   Bacterial expression of Htt fragment containing exon 1, with A2C & A60C cysteine mutations and a 43 polyQ repeat

   Depositor

   Hilal Lashuel

   Article

   Warner JB et al J Am Chem Soc. 2017 Oct 18;139(41):14456

   Insert

   Huntingtin Exon1 (HTT Human)
   

   Use

   Tags

   His6-Ssp DnaB intein

   Expression

   Bacterial

   Mutation

   A2C, A60C; 43 polyQ repeat

   Promoter

   Available since

   Sept. 19, 2018

   Availability

   Academic Institutions and Nonprofits only

   

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10. pTWIN1-His6-Ssp-Htt2-90(A2C)-49Q

    Plasmid

    #114627

    Purpose

    Bacterial expression of Htt fragment containing amino acids 2-90, with A2C cysteine mutation and a 49 polyQ repeat

    Depositor

    Hilal Lashuel

    Article

    Warner JB et al J Am Chem Soc. 2017 Oct 18;139(41):14456

    Insert

    Huntingtin Exon1 fragment (HTT Human)
    

    Use

    Tags

    His6-Ssp DnaB intein

    Expression

    Bacterial

    Mutation

    A2C; 49 polyQ repeat

    Promoter

    Available since

    Sept. 19, 2018

    Availability

    Academic Institutions and Nonprofits only

    

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