We narrowed to 14,145 results for: TIM

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INSR gRNA (BRDN0001148089)

Plasmid

#75507

Purpose

3rd generation lentiviral gRNA plasmid targeting human INSR

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

INSR (INSR Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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INSR gRNA (BRDN0001149243)

Plasmid

#75508

Purpose

3rd generation lentiviral gRNA plasmid targeting human INSR

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

INSR (INSR Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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INSRR gRNA (BRDN0001487067)

Plasmid

#78062

Purpose

3rd generation lentiviral gRNA plasmid targeting human INSRR

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

INSRR (INSRR Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 5, 2016

Availability

Academic Institutions and Nonprofits only

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ABL2 gRNA (BRDN0001146627)

Plasmid

#77178

Purpose

3rd generation lentiviral gRNA plasmid targeting human ABL2

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

ABL2 (ABL2 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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ABL2 gRNA (BRDN0001146737)

Plasmid

#77179

Purpose

3rd generation lentiviral gRNA plasmid targeting human ABL2

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

ABL2 (ABL2 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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HKDC1 gRNA (BRDN0001148616)

Plasmid

#76827

Purpose

3rd generation lentiviral gRNA plasmid targeting human HKDC1

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

HKDC1 (HKDC1 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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HKDC1 gRNA (BRDN0001146218)

Plasmid

#76828

Purpose

3rd generation lentiviral gRNA plasmid targeting human HKDC1

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

HKDC1 (HKDC1 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

Enlarge
HKDC1 gRNA (BRDN0001145441)

Plasmid

#76829

Purpose

3rd generation lentiviral gRNA plasmid targeting human HKDC1

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

HKDC1 (HKDC1 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

Enlarge
HKDC1 gRNA (BRDN0001148023)

Plasmid

#76830

Purpose

3rd generation lentiviral gRNA plasmid targeting human HKDC1

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

HKDC1 (HKDC1 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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PIK3CA gRNA (BRDN0001146906)

Plasmid

#77417

Purpose

3rd generation lentiviral gRNA plasmid targeting human PIK3CA

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

PIK3CA (PIK3CA Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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GRK5 gRNA (BRDN0001148840)

Plasmid

#76274

Purpose

3rd generation lentiviral gRNA plasmid targeting human GRK5

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

GRK5 (GRK5 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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BRDT gRNA (BRDN0001146712)

Plasmid

#77875

Purpose

3rd generation lentiviral gRNA plasmid targeting human BRDT

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

BRDT (BRDT Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 11, 2016

Availability

Academic Institutions and Nonprofits only

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FASTK gRNA (BRDN0001144738)

Plasmid

#77876

Purpose

3rd generation lentiviral gRNA plasmid targeting human FASTK

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

FASTK (FASTK Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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FASTK gRNA (BRDN0001145485)

Plasmid

#77877

Purpose

3rd generation lentiviral gRNA plasmid targeting human FASTK

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

FASTK (FASTK Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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FGFR4 gRNA (BRDN0001147333)

Plasmid

#77570

Purpose

3rd generation lentiviral gRNA plasmid targeting human FGFR4

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

FGFR4 (FGFR4 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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FGFR4 gRNA (BRDN0001146151)

Plasmid

#77571

Purpose

3rd generation lentiviral gRNA plasmid targeting human FGFR4

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

FGFR4 (FGFR4 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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FGFR4 gRNA (BRDN0001148634)

Plasmid

#77572

Purpose

3rd generation lentiviral gRNA plasmid targeting human FGFR4

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

FGFR4 (FGFR4 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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HUNK gRNA (BRDN0001148239)

Plasmid

#75940

Purpose

3rd generation lentiviral gRNA plasmid targeting human HUNK

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

HUNK (HUNK Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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TDP-43_CTD_S273C

Plasmid

#248864

Purpose

Expresses MBP-tagged C-terminal domain of TDP-43 with S273C.

Depositor

Nicolas Fawzi

Article

Rizuan et al Nat Commun. 2025 Nov 26;16(1):10528. doi

Insert

TDP-43_CTD_S273C (TARDBP Human)

Tags

6xHis tags-MBP

Expression

Bacterial

Mutation

changed S273C

Available Since

Dec. 2, 2025

Availability

Academic Institutions and Nonprofits only

Enlarge
TDP-43_CTD_M337A

Plasmid

#248885

Purpose

Edit Expresses 6xHis-tagged C-terminal domain of TDP-43 with M337A.

Depositor

Nicolas Fawzi

Article

Rizuan et al Nat Commun. 2025 Nov 26;16(1):10528. doi

Insert

TDP-43_CTD_M337A (TARDBP Human)

Tags

6xHis-tags

Expression

Bacterial

Mutation

changed M337A

Available Since

Dec. 2, 2025

Availability

Academic Institutions and Nonprofits only

Enlarge
TDP-43_CTD_M339A

Plasmid

#248886

Purpose

Edit Expresses 6xHis-tagged C-terminal domain of TDP-43 with M339A.

Depositor

Nicolas Fawzi

Article

Rizuan et al Nat Commun. 2025 Nov 26;16(1):10528. doi

Insert

TDP-43_CTD_M339A (TARDBP Human)

Tags

6xHis-tags

Expression

Bacterial

Mutation

changed M339A

Available Since

Dec. 2, 2025

Availability

Academic Institutions and Nonprofits only

Enlarge
TDP-43_CTD_L340A

Plasmid

#248887

Purpose

Edit Expresses 6xHis-tagged C-terminal domain of TDP-43 with L340A.

Depositor

Nicolas Fawzi

Article

Rizuan et al Nat Commun. 2025 Nov 26;16(1):10528. doi

Insert

TDP-43_CTD_L340A (TARDBP Human)

Tags

6xHis-tags

Expression

Bacterial

Mutation

changed L340A

Available Since

Dec. 2, 2025

Availability

Academic Institutions and Nonprofits only

Enlarge
pCMV5-MLLn-CAGEn-NES (Nrdj1)

Plasmid

#241412

Purpose

Proximity-triggered Protein Trans-Splicing to generate the splice product MLL-AF9, Figure 2 & Extended Figure 4 in Nature Chemical Biology 20.10 (2024): 1353-1360.

Depositor

Thomas Muir

Article

Lee et al Nat Chem Biol. 2024 Oct;20(10):1353-1360

Insert

MLLn-CAGEn-NES (Nrdj1) (KMT2A Synthetic, Human)

Tags

Myc

Expression

Mammalian

Promoter

CMV

Available Since

Oct. 7, 2025

Availability

Academic Institutions and Nonprofits only

Enlarge
pCMV5-MLLn-CAGEn-NES (Npu)

Plasmid

#241411

Purpose

Proximity-triggered Protein Trans-Splicing to generate the splice product MLL-AF9, Extended Figure 4 in Nature Chemical Biology 20.10 (2024): 1353-1360.

Depositor

Thomas Muir

Article

Lee et al Nat Chem Biol. 2024 Oct;20(10):1353-1360

Insert

MLLn-CAGEn-NES (Npu) (KMT2A Synthetic, Human)

Tags

Myc

Expression

Mammalian

Promoter

CMV

Available Since

Oct. 7, 2025

Availability

Academic Institutions and Nonprofits only

Enlarge
pCMV5-AMLn-CAGEn-NES (Nrdj1)

Plasmid

#241408

Purpose

Proximity-triggered Protein Trans-Splicing to generate the splice product AML1-ETO, Figure 2 in Nature Chemical Biology 20.10 (2024): 1353-1360.

Depositor

Thomas Muir

Article

Lee et al Nat Chem Biol. 2024 Oct;20(10):1353-1360

Insert

AMLn-CAGEn-NES (Nrdj1) (RUNX1 Synthetic, Human)

Tags

Myc

Expression

Mammalian

Promoter

CMV

Available Since

Oct. 7, 2025

Availability

Academic Institutions and Nonprofits only

Enlarge
CAG-NGN3-linker-3xFLAG-Dendra2-HA

Plasmid

#234887

Purpose

Expresses human NGN3 in mammalian cells directly fused to Dendra2 fluorescent protin plus FLAG and HA tags

Depositor

Nancy Papalopulu

Article

Miller et al Dev Cell. 2025 Sep 22;60(18):2518-2532.e

Insert

NGN3-3xFLAG-Dendra2-HA (NEUROG3 Human)

Tags

3xFLAG, Dendra2 and HA

Expression

Mammalian

Promoter

CAG

Available Since

Sept. 26, 2025

Availability

Academic Institutions and Nonprofits only

Enlarge
pCMV5-AMLn-CAGEn-NES (Npu)

Plasmid

#241407

Purpose

Proximity-triggered Protein Trans-Splicing to generate the splice product AML1-ETO, Extended Figure 3 in Nature Chemical Biology 20.10 (2024): 1353-1360.

Depositor

Thomas Muir

Article

Lee et al Nat Chem Biol. 2024 Oct;20(10):1353-1360

Insert

AMLn-CAGEn-NES (Npu) (RUNX1 Synthetic, Human)

Tags

Myc

Expression

Mammalian

Promoter

CMV

Available Since

Sept. 5, 2025

Availability

Academic Institutions and Nonprofits only

Enlarge
CMV_G-PTEN

Plasmid

#227432

Purpose

Expresses the G-PTEN sensor under a CMV promoter

Depositor

Tal Laviv

Article

Kagan et al Nat Methods. 2025 Apr;22(4):764-777. doi

Insert

G-PTEN (Pten Rat)

Tags

mEGFP and sREACh

Expression

Mammalian

Mutation

R14G

Promoter

CMV

Available Since

July 8, 2025

Availability

Academic Institutions and Nonprofits only

Enlarge
pBC001 v3

Plasmid

#161711

Purpose

CMVp-EGFP-[barcode cloning site]-PGKp-Puro-WPRE

Depositor

Nozomu Yachie

Article

Nakayama et al Sci Immunol. 2024 May 24;9(95):eade3814.

Type

Empty backbone

Use

Lentiviral and Synthetic Biology

Expression

Mammalian

Promoter

CMV Promoter

Available Since

July 3, 2025

Availability

Academic Institutions and Nonprofits only

Enlarge
Donor-attp-u6-blank-sgrna-backbone

Plasmid

#234076

Purpose

Blank donor for Perturb Seq landing pad with Pa01 recombinase at the AAVS1 loci

Depositor

Gary Hon

Article

Sivakumar et al bioRxiv [Preprint]. 2025 Jan 23:2025.01.

Insert

sgRNA-Blank

Use

Lentiviral

Expression

Mammalian

Available Since

May 20, 2025

Availability

Academic Institutions and Nonprofits only

Enlarge