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TTR C10S/S85C/A120L

Plasmid

#238112

Purpose

bacterial expression of human TTR mutant

Depositor

Peter Wright

Article

Sun et al Protein Sci. 2024 Sep;33(9):e5101. doi:

Insert

TTR (TTR Human)

Expression

Bacterial

Mutation

C10S/S85C/A120L

Promoter

T7

Available Since

July 23, 2025

Availability

Academic Institutions and Nonprofits only

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TTR C10S/S85C/A120S

Plasmid

#238113

Purpose

bacterial expression of human TTR mutant

Depositor

Peter Wright

Article

Sun et al Protein Sci. 2024 Sep;33(9):e5101. doi:

Insert

TTR (TTR Human)

Expression

Bacterial

Mutation

C10S/S85C/A120S

Promoter

T7

Available Since

July 23, 2025

Availability

Academic Institutions and Nonprofits only

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His6-tev-G(TTR A25T/I26V)

Plasmid

#238117

Purpose

bacterial expression of human TTR mutants

Depositor

Peter Wright

Article

Sun et al J Am Chem Soc. 2024 Jan 10;146(1):532-54

Insert

TTR (TTR Human)

Tags

His6tev-G

Expression

Bacterial

Mutation

A25T/I26V

Promoter

T7

Available Since

July 21, 2025

Availability

Academic Institutions and Nonprofits only

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pAG8Ha-PU.1_DBD(168-270)

Plasmid

#188053

Purpose

Expresses His8-PU.1_DBD(168-270) with a TEV site for removal of the His8 tag.

Depositor

David Libich

Article

Selig et al Proc Natl Acad Sci U S A. 2025 May 20;12

Insert

SPI1 (SPI1 Human)

Tags

His8

Expression

Bacterial

Mutation

deleted amino acids 1-167

Promoter

T7

Available Since

June 9, 2025

Availability

Academic Institutions and Nonprofits only

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TTR F87E

Plasmid

#238075

Purpose

Bacterial expression of human TTR mutants

Depositor

Peter Wright

Article

Leach et al J Mol Biol. 2024 Aug 15;436(16):168673.

Insert

TTR (TTR Human)

Expression

Bacterial

Mutation

F87E

Promoter

T7

Available Since

June 5, 2025

Availability

Academic Institutions and Nonprofits only

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AAV-DIO-mPOMC

Plasmid

#239042

Purpose

Overexpression of POMC gene

Depositor

Qingchun Tong

Article

Xu et al Cell Rep. 2023 May 30;42(5):112502. doi:

Insert

mPOMC (Pomc Mouse)

Use

AAV

Promoter

CAG

Available Since

May 21, 2025

Availability

Academic Institutions and Nonprofits only

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pcDNA3 JDM37-GFPnb-mCh

Plasmid

#235666

Purpose

Expresses designed activator of Hsp70 tagged with a GFP nano body and mCherry

Depositor

David Baker

Article

Zhang et al Cell Chem Biol. 2025 Feb 4:S2451-9456(25

Insert

JDM37-GFPnb-mCh (PMCH Human, Synthetic)

Tags

GFP nanobody and mCherry

Expression

Mammalian

Promoter

CMV

Available Since

April 23, 2025

Availability

Academic Institutions and Nonprofits only

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shRNA_circNUDC_2

Plasmid

#215231

Purpose

Supression of shcircNUDC(5,RI,6)_2 expression

Depositor

Sefi Rosenbluh

Article

Liu et al Nat Cell Biol. 2024 Aug;26(8):1359-1372.

Insert

circNUDC shRNA 2 (NUDC Human)

Use

Lentiviral

Available Since

March 17, 2025

Availability

Academic Institutions and Nonprofits only

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shRNA_circNUDC_1

Plasmid

#215232

Purpose

Supression of shcircNUDC(5,RI,6)_1 expression

Depositor

Sefi Rosenbluh

Article

Liu et al Nat Cell Biol. 2024 Aug;26(8):1359-1372.

Insert

circNUDC shRNA 1 (NUDC Human)

Use

Lentiviral

Available Since

March 17, 2025

Availability

Academic Institutions and Nonprofits only

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shRNA_NUDC_2

Plasmid

#215211

Purpose

Supression of shNUDC_2 expression

Depositor

Sefi Rosenbluh

Article

Liu et al Nat Cell Biol. 2024 Aug;26(8):1359-1372.

Insert

NUDC shRNA 2 (NUDC Human)

Use

Lentiviral

Available Since

March 17, 2025

Availability

Academic Institutions and Nonprofits only

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shRNA_NUDC_1

Plasmid

#215212

Purpose

Supression of shNUDC_1 expression

Depositor

Sefi Rosenbluh

Article

Liu et al Nat Cell Biol. 2024 Aug;26(8):1359-1372.

Insert

NUDC shRNA 1 (NUDC Human)

Use

Lentiviral

Available Since

March 17, 2025

Availability

Academic Institutions and Nonprofits only

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TFORF0127

Plasmid

#143012

Purpose

Lentiviral vector for overexpressing transcription factor ORFs with unique 24-bp barcodes. Barcodes facilitate identification of transcription factors in pooled screens.

Depositor

Feng Zhang

Article

Joung et al Cell. 2023 Jan 5;186(1):209-229.e26. doi

Insert

SP8 (SP8 Human)

Use

Lentiviral

Expression

Mammalian

Promoter

EF1a

Available Since

Feb. 27, 2025

Availability

Academic Institutions and Nonprofits only

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pJExpress401-KDAC8 D101N

Plasmid

#224348

Purpose

Expresses human KDAC8 (HDAC8) D101N in E. coli

Depositor

Terry Watt

Article

Toro et al Biochemistry. 2021 Aug 24;60(33):2524-25

Insert

KDAC8 (HDAC8 Human)

Tags

TEV-cleavable His6

Expression

Bacterial

Mutation

Aspartate 101 mutated to asparagine

Promoter

T5

Available Since

Feb. 19, 2025

Availability

Industry, Academic Institutions, and Nonprofits

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pcDNA3.1-myc:FRB:gs10:Cul1(dC501)

Plasmid

#228533

Purpose

A fragment of humanCul1 protein in fusion with FRB domain through a flexible glycine-serine linker.

Depositor

Roman Jerala

Article

Verbic et al ACS Synth Biol. 2024 Mar 15;13(3):792-80

Insert

myc:FRB:gs10:Cul1(dC501) (CUL1 Human, Synthetic)

Tags

myc

Expression

Mammalian

Promoter

CMV

Available Since

Jan. 3, 2025

Availability

Academic Institutions and Nonprofits only

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pCAG-RhoA*

Plasmid

#198716

Purpose

Expresses gRNA resistant RhoA under the CAG promoter in mammalian cells

Depositor

Takeshi Imai

Article

Fujimoto et al Dev Cell. 2023 Jul 24;58(14):1221-1236.e

Insert

RhoA (Rhoa Mouse)

Expression

Mammalian

Mutation

It has mutations that is resistant to the RhoA gR…

Promoter

CAG

Available Since

Dec. 11, 2024

Availability

Academic Institutions and Nonprofits only

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pBK_Gal4-DBD-Ar

Plasmid

#227098

Purpose

Ar receptor overexpression for luciferase and barcode assays

Depositor

Michael Wehr

Article

Popovic et al Biomed Pharmacother. 2024 Nov;180:117523

Insert

Ar (Ar Mouse)

Expression

Mammalian

Available Since

Dec. 4, 2024

Availability

Academic Institutions and Nonprofits only

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pAcBac1-Pyl-TAA

Plasmid

#228783

Purpose

Pyl aaRS/tRNA system for mammalian TAA suppression

Depositor

Abhishek Chatterjee

Article

Osgood et al Angew Chem Int Ed Engl. 2023 May 2;62(19

Inserts

PylRS
PytR

Use

Baculoviral

Expression

Mammalian

Mutation

TAA suppressor

Available Since

Nov. 21, 2024

Availability

Academic Institutions and Nonprofits only

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pJExpress401-KDAC8 D101R

Plasmid

#224349

Purpose

Expresses human KDAC8 (HDAC8) D101R in E. coli

Depositor

Terry Watt

Article

Toro et al Biochemistry. 2021 Aug 24;60(33):2524-25

Insert

KDAC8 (HDAC8 Human)

Tags

TEV-cleavable His6

Expression

Bacterial

Mutation

Aspartate 101 mutated to arginine

Promoter

T5

Available Since

Oct. 28, 2024

Availability

Industry, Academic Institutions, and Nonprofits

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pJExpress401-KDAC8 D101A

Plasmid

#224347

Purpose

Expresses human KDAC8 (HDAC8) D101A in E. coli

Depositor

Terry Watt

Article

Toro et al Biochemistry. 2021 Aug 24;60(33):2524-25

Insert

KDAC8 (HDAC8 Human)

Tags

TEV-cleavable His6

Expression

Bacterial

Mutation

Aspartate 101 mutated to alanine

Promoter

T5

Available Since

Oct. 22, 2024

Availability

Industry, Academic Institutions, and Nonprofits

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pAM316 pET28a-GGG-Titin[V15P]-23-K-9-C-14cyclinB-10GS-Y

Plasmid

#226349

Purpose

Expression of Titin V15P substrate with GS tail

Depositor

Andreas Martin

Article

Jonsson et al Sci Adv. 2022 Dec 23;8(51):eadd9520. doi

Insert

titin (TTN Human)

Expression

Bacterial

Mutation

V15P

Available Since

Oct. 18, 2024

Availability

Academic Institutions and Nonprofits only

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