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pBABE-IFNgR1-QY-tTA-SV40-puro-T2A-TagBFP

Plasmid

#254090

Purpose

Retroviral transfer vector for IFNgR1-tTA fusion gene expression, QY linker, puromycin selection marker, for CyCLoPs platform.

Depositor

Jun Huh

Article

Lu et al Cell. 2026 Feb 5;189(3):939-955.e26. doi

Insert

IFNgR1-tTA

Use

Retroviral

Available Since

March 30, 2026

Availability

Academic Institutions and Nonprofits only

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pBABE-IL17RA-QL-tTA-SV40-puro-T2A-TagBFP

Plasmid

#254078

Purpose

Retroviral transfer vector for IL17RA-tTA fusion gene expression, QY linker, puromycin selection marker, for CyCLoPs platform.

Depositor

Jun Huh

Article

Lu et al Cell. 2026 Feb 5;189(3):939-955.e26. doi

Insert

IL17RA-tTA

Use

Retroviral

Available Since

March 30, 2026

Availability

Academic Institutions and Nonprofits only

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pBABE-IL10RB-QY-tTA-SV40-puro-T2A-TagBFP

Plasmid

#254091

Purpose

Retroviral transfer vector for IL10RB-tTA fusion gene expression, QY linker, puromycin selection marker, for CyCLoPs platform.

Depositor

Jun Huh

Article

Lu et al Cell. 2026 Feb 5;189(3):939-955.e26. doi

Insert

IL10RB-tTA

Use

Retroviral

Available Since

March 30, 2026

Availability

Academic Institutions and Nonprofits only

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pBABE-TNFR1-QL-tTA-SV40-puro-T2A-TagBFP

Plasmid

#254092

Purpose

Retroviral transfer vector for TNFR1-tTA fusion gene expression, QL linker, puromycin selection marker, for CyCLoPs platform.

Depositor

Jun Huh

Article

Lu et al Cell. 2026 Feb 5;189(3):939-955.e26. doi

Insert

TNFR1-tTA

Use

Retroviral

Available Since

March 30, 2026

Availability

Academic Institutions and Nonprofits only

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pBABE-TNFR2-QL-tTA-SV40-puro-T2A-TagBFP

Plasmid

#254093

Purpose

Retroviral transfer vector for TNFR2fusion gene expression, QL linker, puromycin selection marker, for CyCLoPs platform.

Depositor

Jun Huh

Article

Lu et al Cell. 2026 Feb 5;189(3):939-955.e26. doi

Insert

TNFR2-tTA

Use

Retroviral

Available Since

March 30, 2026

Availability

Academic Institutions and Nonprofits only

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pBABE-TGFBR1-QY-tTA-SV40-puro-T2A-TagBFP

Plasmid

#254094

Purpose

Retroviral transfer vector for TGFBR1-tTA fusion gene expression, QY linker, puromycin selection marker, for CyCLoPs platform.

Depositor

Jun Huh

Article

Lu et al Cell. 2026 Feb 5;189(3):939-955.e26. doi

Insert

TGFBR1-tTA

Use

Retroviral

Available Since

March 30, 2026

Availability

Academic Institutions and Nonprofits only

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pBABE-IL17RB-QL-tTA-SV40-puro-T2A-TagBFP

Plasmid

#254079

Purpose

Retroviral transfer vector for IL17RB-tTA fusion gene expression, QL linker, puromycin selection marker, for CyCLoPs platform.

Depositor

Jun Huh

Article

Lu et al Cell. 2026 Feb 5;189(3):939-955.e26. doi

Insert

IL17RB-tTA

Use

Retroviral

Available Since

March 30, 2026

Availability

Academic Institutions and Nonprofits only

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MIGR1-TGFBR2-TEV-SV40-hygro

Plasmid

#254115

Purpose

Retroviral transfer vector for TGFBR2-TEV fusion gene expression, Hygromycin selection marker, for CyCLoPs platform.

Depositor

Jun Huh

Article

Lu et al Cell. 2026 Feb 5;189(3):939-955.e26. doi

Insert

TGFBR2-TEV

Use

Retroviral

Mutation

AA194: GGT to GGC synonymous mutation

Available Since

March 30, 2026

Availability

Academic Institutions and Nonprofits only

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MIGR1-IL1R1-TEV-SV40-hygro

Plasmid

#254103

Purpose

Retroviral transfer vector for IL1R1-TEV fusion gene expression, Hygromycin selection marker, for CyCLoPs platform.

Depositor

Jun Huh

Article

Lu et al Cell. 2026 Feb 5;189(3):939-955.e26. doi

Insert

IL1R1-TEV

Use

Retroviral

Mutation

AA370: TAC to TAT synonymous mutation

Available Since

March 30, 2026

Availability

Academic Institutions and Nonprofits only

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HSPD1-i7 -HT2

Plasmid

#236333

Purpose

Inducibly expresses HSPD1 tagged with HaloTag2 at the relative location of intron 7 in the HSPD1 gene.

Depositor

Ophir Shalem

Article

Sansbury et al bioRxiv. 2023 Jul 14:2023.07.13.548611.

Insert

HSPD1 (HSPD1 Human)

Use

Lentiviral

Tags

HaloTag2 insertion at intron 7

Expression

Mammalian

Available Since

March 25, 2026

Availability

Academic Institutions and Nonprofits only

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CALR-i2-HT2

Plasmid

#236334

Purpose

Inducibly expresses CALR tagged with HaloTag2 at the relative location of intron 2 in the CALR gene.

Depositor

Ophir Shalem

Article

Sansbury et al bioRxiv. 2023 Jul 14:2023.07.13.548611.

Insert

CALR (CALR Human)

Use

Lentiviral

Tags

HaloTag2 internal insertion at intron 2

Expression

Mammalian

Available Since

March 25, 2026

Availability

Academic Institutions and Nonprofits only

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EPHA2-i16-HT2

Plasmid

#236335

Purpose

Inducibly expresses EPHA2 tagged with HaloTag2 at the relative location of intron 16 in the EPHA2 gene.

Depositor

Ophir Shalem

Article

Sansbury et al bioRxiv. 2023 Jul 14:2023.07.13.548611.

Insert

EPHA2 (EPHA2 Human)

Use

Lentiviral

Tags

HaloTag2 internal insertion at intron 16

Expression

Mammalian

Available Since

March 25, 2026

Availability

Academic Institutions and Nonprofits only

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pIF1-S39E-GFP

Plasmid

#206937

Purpose

Plasmid expressing the mutant S39E of human IF1 fused in C-terminal with GFP

Depositor

José Cuezva

Article

Romero-Carraminana et al Commun Biol. 2023 Aug 12;6(1):836. doi:

Insert

S39E mutant of human IF1 (ATPase inhibitory factor 1)

Tags

GFP

Expression

Mammalian

Mutation

Changed serine 39 for a glutamic acid

Promoter

CMV

Available Since

Jan. 21, 2026

Availability

Academic Institutions and Nonprofits only

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M3-dCAS9-DNMT3A

Plasmid

#220237

Purpose

Expresses dCAS9-DNMT3A fusion protein and double marker GFP-T2A-Puro under independent promoters

Depositor

Maja Jagodic

Article

Kakhki et al bioRxiv 2025.03.15.641804; doi: 10.1101/

Inserts

M3-dCAS9-DNMT3A (dCas9-3A)
GFP-T2A-Puro

Use

CRISPR

Expression

Mammalian

Available Since

Jan. 13, 2026

Availability

Academic Institutions and Nonprofits only

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pMDS1

Plasmid

#239460

Purpose

For simultaneous monitoring of both transcription and translation of genes in plant tissues: C-terminus fusion

Depositor

Miguel de Lucas

Article

Banda et al Sci. Adv., 11, eadw9153 (2025)

Type

Empty backbone

Tags

VENUS:3xHA:2A:mTurqN7

Expression

Bacterial and Plant

Available Since

Oct. 6, 2025

Availability

Academic Institutions and Nonprofits only

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pMDS2

Plasmid

#239459

Purpose

Simultaneous monitoring of transcription and translation of genes in plant tissues: N- terminus fusion

Depositor

Miguel de Lucas

Article

Banda et al Sci. Adv., 11, eadw9153 (2025)

Type

Empty backbone

Tags

3xHA:VENUS:2A:mTurqN7

Expression

Bacterial and Plant

Available Since

Aug. 29, 2025

Availability

Academic Institutions and Nonprofits only

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pCS2+8-CYP2A6(C82A)-flag-tev-his

Plasmid

#227166

Purpose

For overexpression of CYP2A6 C82A mutant in mammalian cells and purification.

Depositor

Yimon Aye

Article

Liu et al Cell. 2024 Dec 26;187(26):7450-7469.e29.

Insert

CYP2A6 (CYP2A6 Human)

Tags

Flag and His6

Expression

Mammalian

Mutation

changed cysteine 82 to alanine

Promoter

CMV and SP6

Available Since

Aug. 19, 2025

Availability

Academic Institutions and Nonprofits only

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pCS2+8-cyp-33e1-flag-tev-halo-his

Plasmid

#227151

Purpose

For T-REX experiments of cyp-33e1. A reactive electrophilic species (RES) Sensor.

Depositor

Yimon Aye

Article

Liu et al Cell. 2024 Dec 26;187(26):7450-7469.e29.

Insert

cyp-33e1 (cyp-33E1 Nematode)

Tags

Flag, HaloTag, and His6

Expression

Mammalian

Promoter

CMV and SP6

Available Since

Aug. 19, 2025

Availability

Academic Institutions and Nonprofits only

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pCS2+8-CYP2A6-flag-tev-halo-his

Plasmid

#227154

Purpose

For T-REX experiments of CYP2A6. A reactive electrophilic species (RES) Sensor.

Depositor

Yimon Aye

Article

Liu et al Cell. 2024 Dec 26;187(26):7450-7469.e29.

Insert

CYP2A6 (CYP2A6 Human)

Tags

Flag, HaloTag, and His6

Expression

Mammalian

Promoter

CMV and SP6

Available Since

Aug. 19, 2025

Availability

Academic Institutions and Nonprofits only

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pLG-mLRRC45 (158 a.a.)

Plasmid

#240067

Purpose

ITT reporter plasmid for cold and osmotic stress

Depositor

Hodaka Fujii

Article

Maruyama et al Biol Methods Protoc. 2025 Jun 14;10(1):b

Insert

LRRC45 C-terminal 158 a.a. (Lrrc45 Mouse)

Use

Retroviral

Tags

LexA DNA-binding (DB) domain + Gal4 transactivati…

Expression

Mammalian

Promoter

LTR

Available Since

July 29, 2025

Availability

Academic Institutions and Nonprofits only

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