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pKlab240-pcDNA3-BRCA1(1314-end)-Y1845D-V5-3xFLAG

Plasmid

#249016

Purpose

This plasmid expresses the C-terminally 3x-FLAG tagged BRCT domain that contains the Y1845D mutation

Depositor

Georgios Karras

Article

Gracia et al Cell Rep. 2024 Feb 27;43(2):113803. doi:

Insert

BRCA1(1314aa-end) (BRCA1 Human)

Tags

3x-FLAG-V5

Expression

Mammalian

Mutation

Y1845D

Promoter

CMV Promoter

Available Since

Jan. 21, 2026

Availability

Academic Institutions and Nonprofits only

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pKlab981-pcDNA3-BRCA1(1314-end)-V1736A-V5-3xFLAG

Plasmid

#249018

Purpose

This plasmid expresses the C-terminally 3x-FLAG tagged BRCT domain that contains the V1736A mutation

Depositor

Georgios Karras

Article

Gracia et al Cell Rep. 2024 Feb 27;43(2):113803. doi:

Insert

BRCA1(1314aa-end) (BRCA1 Human)

Tags

3x-FLAG-V5

Expression

Mammalian

Mutation

V1736A

Promoter

CMV Promoter

Available Since

Jan. 21, 2026

Availability

Academic Institutions and Nonprofits only

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pKlab224-pcDNA3-BRCA1(1314-end)-R1699W-V5-3xFLAG

Plasmid

#249019

Purpose

This plasmid expresses the C-terminally 3x-FLAG tagged BRCT domain that contains the R1699W mutation

Depositor

Georgios Karras

Article

Gracia et al Cell Rep. 2024 Feb 27;43(2):113803. doi:

Insert

BRCA1(1314aa-end) (BRCA1 Human)

Tags

3x-FLAG-V5

Expression

Mammalian

Mutation

R1699W

Promoter

CMV Promoter

Available Since

Jan. 21, 2026

Availability

Academic Institutions and Nonprofits only

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pKlab223-pcDNA3-BRCA1(1314-end)-R1699Q-V5-3xFLAG

Plasmid

#249020

Purpose

This plasmid expresses the C-terminally 3x-FLAG tagged BRCT domain that contains the R1699Q mutation

Depositor

Georgios Karras

Article

Gracia et al Cell Rep. 2024 Feb 27;43(2):113803. doi:

Insert

BRCA1(1314aa-end) (BRCA1 Human)

Tags

3x-FLAG-V5

Expression

Mammalian

Mutation

R1699Q

Promoter

CMV Promoter

Available Since

Jan. 21, 2026

Availability

Academic Institutions and Nonprofits only

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pKlab228-pcDNA3-BRCA1(1314-end)-S1715R-V5-3xFLAG

Plasmid

#249021

Purpose

This plasmid expresses the C-terminally 3x-FLAG tagged BRCT domain that contains the S1715R mutation

Depositor

Georgios Karras

Article

Gracia et al Cell Rep. 2024 Feb 27;43(2):113803. doi:

Insert

BRCA1(1314aa-end) (BRCA1 Human)

Tags

3x-FLAG-V5

Expression

Mammalian

Mutation

S1715R

Promoter

CMV Promoter

Available Since

Jan. 21, 2026

Availability

Academic Institutions and Nonprofits only

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pKlab189-pcDNA3-BRCA1(1314-end)-A1708E-V5-3xFLAG

Plasmid

#249022

Purpose

This plasmid expresses the C-terminally 3x-FLAG tagged BRCT domain that contains the A1708E mutation

Depositor

Georgios Karras

Article

Gracia et al Cell Rep. 2024 Feb 27;43(2):113803. doi:

Insert

BRCA1(1314aa-end) (BRCA1 Human)

Tags

3x-FLAG-V5

Expression

Mammalian

Mutation

A1708E

Promoter

CMV Promoter

Available Since

Jan. 21, 2026

Availability

Academic Institutions and Nonprofits only

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pKlab525-pcDNA3-3xFLAG-V5-BRCA1(1314-end)-WT-STOP

Plasmid

#249008

Purpose

This plasmid expresses the N-terminally 3x-FLAG tagged BRCT domain

Depositor

Georgios Karras

Article

Gracia et al Cell Rep. 2024 Feb 27;43(2):113803. doi:

Insert

BRCA1(1314aa-end) (BRCA1 Human)

Tags

3x-FLAG-V5

Expression

Mammalian

Promoter

CMV Promoter

Available Since

Jan. 21, 2026

Availability

Academic Institutions and Nonprofits only

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pKlab521-pcDNA3-3xFLAG-V5-BRCA1(1314-end)-Y1845F-STOP

Plasmid

#249009

Purpose

This plasmid expresses the N-terminally 3x-FLAG tagged BRCT domain that contains the Y1845F mutation

Depositor

Georgios Karras

Article

Gracia et al Cell Rep. 2024 Feb 27;43(2):113803. doi:

Insert

BRCA1(1314aa-end) (BRCA1 Human)

Tags

3x-FLAG-V5

Expression

Mammalian

Mutation

Y1845F

Promoter

CMV Promoter

Available Since

Jan. 21, 2026

Availability

Academic Institutions and Nonprofits only

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pKlab522-pcDNA3-3xFLAG-V5-BRCA1(1314-end)-Y1845D-STOP

Plasmid

#249010

Purpose

This plasmid expresses the N-terminally 3x-FLAG tagged BRCT domain that contains the Y1845D mutation

Depositor

Georgios Karras

Article

Gracia et al Cell Rep. 2024 Feb 27;43(2):113803. doi:

Insert

BRCA1(1314aa-end) (BRCA1 Human)

Tags

3x-FLAG-V5

Expression

Mammalian

Mutation

Y1845D

Promoter

CMV Promoter

Available Since

Jan. 21, 2026

Availability

Academic Institutions and Nonprofits only

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pKlab524-pcDNA3-3xFLAG-V5-BRCA1(1314-end)-G1788V-STOP

Plasmid

#249011

Purpose

This plasmid expresses the N-terminally 3x-FLAG tagged BRCT domain that contains the G1788V mutation

Depositor

Georgios Karras

Article

Gracia et al Cell Rep. 2024 Feb 27;43(2):113803. doi:

Insert

BRCA1(1314aa-end) (BRCA1 Human)

Tags

3x-FLAG-V5

Expression

Mammalian

Mutation

G1788V

Promoter

CMV Promoter

Available Since

Jan. 21, 2026

Availability

Academic Institutions and Nonprofits only

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pKlab518-pcDNA3-3xFLAG-V5-BRCA1(1314-end)-A1708E-STOP

Plasmid

#249012

Purpose

This plasmid expresses the N-terminally 3x-FLAG tagged BRCT domain that contains the A1708E mutation

Depositor

Georgios Karras

Article

Gracia et al Cell Rep. 2024 Feb 27;43(2):113803. doi:

Insert

BRCA1(1314aa-end) (BRCA1 Human)

Tags

3x-FLAG-V5

Expression

Mammalian

Mutation

A1708E

Promoter

CMV Promoter

Available Since

Jan. 21, 2026

Availability

Academic Institutions and Nonprofits only

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pKlab979-pcDNA3-BRCA1(1314-end)-A1708V-V5-3xFLAG

Plasmid

#249014

Purpose

This plasmid expresses the C-terminally 3x-FLAG tagged BRCT domain that contains the A1708V mutation

Depositor

Georgios Karras

Article

Gracia et al Cell Rep. 2024 Feb 27;43(2):113803. doi:

Insert

BRCA1(1314aa-end) (BRCA1 Human)

Tags

3x-FLAG-V5

Expression

Mammalian

Mutation

A1708V

Promoter

CMV Promoter

Available Since

Jan. 21, 2026

Availability

Academic Institutions and Nonprofits only

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pCambia1300_cLUC-NLRa

Plasmid

#233526

Purpose

Expresses split luciferase fusion cLUC-NLRa in planta

Depositor

Brande Wulff

Article

Chen et al Science. 2025 Mar 28;387(6741):1402-1408

Insert

Sr62NLRa

Tags

C-terminal fragment of Luciferase

Expression

Plant

Promoter

35S

Available Since

Dec. 1, 2025

Availability

Academic Institutions and Nonprofits only

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pDEST-ITGB1-V1

Plasmid

#215454

Purpose

Expression vector with integrin beta1 tagged with the BiFC V1 fragment

Depositor

Johanna Ivaska

Article

Conway et al Nat Cell Biol. 2025 May 26. doi: 10.1038

Insert

ITGB1 (ITGB1 Human)

Tags

Venus fragment 1 (V1)

Expression

Mammalian

Mutation

Silent mutations added to disrupt shRNA binding a…

Promoter

CMV

Available Since

Nov. 3, 2025

Availability

Industry, Academic Institutions, and Nonprofits

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pPB-CAG-shLRRK2-mCherry-CAAX

Plasmid

#227686

Purpose

Membrane tethered mCherry and shRNA targeting LRRK2

Depositor

Cagla Eroglu

Article

Wang et al eLife 2025 [Reviewed Preprint] 14:RP1075

Insert

LRRK2 shRNA (Lrrk2 Mouse)

Expression

Mammalian

Available Since

Oct. 1, 2025

Availability

Academic Institutions and Nonprofits only

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pPB-CAG-shAtg7-mCherry-CAAX

Plasmid

#227687

Purpose

Membrane tethered mCherry and shRNA targeting Atg7

Depositor

Cagla Eroglu

Article

Wang et al eLife 2025 [Reviewed Preprint] 14:RP1075

Insert

Atg7 shRNA (Atg7 Mouse)

Expression

Mammalian

Available Since

Oct. 1, 2025

Availability

Academic Institutions and Nonprofits only

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pAAV-hSyn-GRAB-HaloDAmut

Plasmid

#234409

Purpose

Expresses the chemigenetic dopamine (DA) control sensor GRAB_HaloDAmut in neurons

Depositor

Yulong Li

Article

Zheng et al Science. 2025 Jun 5;388: 6751. doi: http

Insert

GPCR activation based chemigenetic dopamine (DA) control sensor GRAB_HaloDAmut

Use

AAV

Promoter

hSyn

Available Since

Sept. 19, 2025

Availability

Academic Institutions and Nonprofits only

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pNK091

Plasmid

#219769

Purpose

MoClo-compatible Level P vector carrying fungal bioluminescence system lacking luciferase gene

Depositor

Karen Sarkisyan

Article

Balakireva et al bioRxiv 2025.02.17.636591; doi: https://

Insert

pNos-KanR-ocsT | p35S-nnHispS-ocsT | pCmYLCV-npgA-ATPT | p35S-nnCPH-ocsT | pFMV-nnH3H-nosT

Use

Synthetic Biology

Expression

Plant

Promoter

pNos-KanR-ocsT | p35S-nnHispS-ocsT | pCmYLCV-npgA…

Available Since

July 21, 2025

Availability

Academic Institutions and Nonprofits only

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pCambia1300_cLUC-NLRb

Plasmid

#233527

Purpose

Expresses split luciferase fusion cLUC-NLRb in planta

Depositor

Brande Wulff

Article

Chen et al Science. 2025 Mar 28;387(6741):1402-1408

Insert

Sr62NLRb

Tags

C-terminal fragment of Luciferase

Expression

Plant

Promoter

35S

Available Since

June 4, 2025

Availability

Academic Institutions and Nonprofits only

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pDONR221-ZNF883

Plasmid

#101608

Purpose

Donor Vector containing ZNF883 transcription factor, part of the Human TFome Collection

Depositor

George Church

Article

Ng et al Nat Biotechnol. 2021 Apr;39(4):510-519.

Insert

ZNF883 (ZNF883 Human)

Use

Gateway Cloning

Mutation

Last nucleotide of stop codon removed to allow fo…

Available Since

March 31, 2022

Availability

Academic Institutions and Nonprofits only

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