We narrowed to 8,411 results for: APP

1. AAV2_CAG_oROS-HT(C199S)_WPRE

   Plasmid

   #216415

   Purpose

   Encodes the loss-of-function mutation C199S of genetically encoded, chemigenetic fluorescent peroxide sensor oROS-HT in AAV viral vectors

   Depositor

   Andre Berndt

   Article

   Lee et al bioRxiv 2024.02.06.579232

   Insert

   oROS-HT(C199S)
   

   Use

   AAV

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   CAG

   Available since

   April 24, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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2. FENEF-Sensor

   Plasmid

   #208930

   Purpose

   in vitro p38-Sensor for luminescent detection of p38-activity

   Depositor

   Attila Reményi

   Article

   Poti et al Int J Mol Sci. 2023 Oct 3;24(19):14854.

   Insert

   FENEF sequence from human ATF2 with phospho site (ATF2 Human)
   

   Use

   Tags

   HISx6, MBP, and Smbit

   Expression

   Bacterial

   Mutation

   Promoter

   T7

   Available since

   April 2, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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3. PB-PARP1-del.p119K120S–eGFP

   Plasmid

   #211554

   Purpose

   A piggyBac vector containing CMV-PARP1-del.p119K120S-eGFP-IRES-Neo cassette.

   Depositor

   Chris Lord

   Article

   Krastev et al Nat Cell Biol. 2022 Jan;24(1):62-73. doi

   Insert

   PARP1 (PARP1 Human)
   

   Use

   Piggybac

   Tags

   eGFP

   Expression

   Mammalian

   Mutation

   deletion of amino acids 119K 120S

   Promoter

   CMV

   Available since

   Feb. 8, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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4. pEGFP-N1-PARP1-delM43;F44I

   Plasmid

   #211579

   Purpose

   CMV driven PARP1-delM43;F44I -eGFP expressing construct with IRES-Neomycin selection

   Depositor

   Chris Lord

   Article

   Krastev et al Nat Cell Biol. 2022 Jan;24(1):62-73. doi

   Insert

   PARP1 (PARP1 Human)
   

   Use

   Tags

   eGFP

   Expression

   Mammalian

   Mutation

   Contains deletion of M43 and F44I

   Promoter

   Available since

   Feb. 8, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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5. pGEX-6P-1-gp78 RING

   Plasmid

   #185353

   Purpose

   RING domain-containing GST fusion protein for ubiquitination assays.

   Depositor

   Allan Weissman

   Article

   Smith et al PLoS Biol. 2021 Dec 8;19(12):e3001474. d

   Insert

   gp78 cytoplasmic domain (AMFR Human)
   

   Use

   Tags

   GST

   Expression

   Bacterial

   Mutation

   Stop codon after aa 393

   Promoter

   Available since

   Oct. 16, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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6. pGEX-6P-1-gp78 429-611

   Plasmid

   #185354

   Purpose

   GST fusion protein for quantification of gp78 levels

   Depositor

   Allan Weissman

   Article

   Smith et al PLoS Biol. 2021 Dec 8;19(12):e3001474. d

   Insert

   gp78 (AMFR Human)
   

   Use

   Tags

   GST

   Expression

   Bacterial

   Mutation

   aa 429-611 only

   Promoter

   Available since

   July 10, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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7. pGEX-6P-1 AUP1 292-410 5E

   Plasmid

   #185332

   Purpose

   Bacterial expression of AUP1 with GST fusion protein for binding assays

   Depositor

   Allan Weissman

   Article

   Smith et al PLoS Biol. 2021 Dec 8;19(12):e3001474. d

   Insert

   AUP1 (AUP1 Human)
   

   Use

   Tags

   GST

   Expression

   Bacterial

   Mutation

   aa 292-410 only, with mutations R382E/Q383E/K390E…

   Promoter

   Available since

   July 10, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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8. pGEX-6P-1 AUP1 292-410 A397D

   Plasmid

   #185333

   Purpose

   Bacterial expression of AUP1 with GST fusion protein for binding assays

   Depositor

   Allan Weissman

   Article

   Smith et al PLoS Biol. 2021 Dec 8;19(12):e3001474. d

   Insert

   AUP1 (AUP1 Human)
   

   Use

   Tags

   GST

   Expression

   Bacterial

   Mutation

   aa 292-410 only, with mutation A379D

   Promoter

   Available since

   July 10, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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9. pAAV-Tbg-CES2C-ΔC-S230A

   Plasmid

   #200561

   Purpose

   Secreted mouse CES2C S230A mutant driven by heptaocyte-specific promoter in AAV viral vector

   Depositor

   Jonathan Long

   Article

   Wei et al Cell Metab. 2023 Apr 28:S1550-4131(23)00

   Insert

   Mouse Carboxylesterase 2C S230A mutant delta C-terminal (Ces2c Mouse)
   

   Use

   AAV

   Tags

   Flag

   Expression

   Mutation

   Promoter

   TBG promoter

   Available since

   May 8, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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10. pCIneo-lambdaN-HA-HsEDC4_1-538_V

    Plasmid

    #147782

    Purpose

    Mammalian Expression of HsEDC4_1-538

    Depositor

    Elisa Izaurralde

    Article

    Braun et al Nat Struct Mol Biol. 2012 Dec;19(12):132

    Insert

    HsEDC4_1-538 (EDC4 Human)
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    one non silent mutation I286T compared to the seq…

    Promoter

    Available since

    March 16, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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11. pCIneo-lambdaN-HA-HsEDC4-del974-1265_V

    Plasmid

    #147786

    Purpose

    Mammalian Expression of HsEDC4-del974-1265

    Depositor

    Elisa Izaurralde

    Article

    Braun et al Nat Struct Mol Biol. 2012 Dec;19(12):132

    Insert

    HsEDC4-del974-1265 (EDC4 Human)
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    one non silent mutation I286T compared to the seq…

    Promoter

    Available since

    March 16, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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12. pEGFP-C1-G2BRgp78

    Plasmid

    #185344

    Purpose

    Expression of soluble G2BR, amino acids 575-600 of human gp78

    Depositor

    Allan Weissman

    Article

    Smith et al PLoS Biol. 2021 Dec 8;19(12):e3001474. d

    Insert

    gp78 aa 574-600 (G2BR) (AMFR Human)
    

    Use

    Tags

    EGFP

    Expression

    Mammalian

    Mutation

    aa 575-600 only

    Promoter

    Available since

    Feb. 14, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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13. pETDUET-GST-AUP1 379-410:Ube2G2

    Plasmid

    #185335

    Purpose

    Used for co-expression of the AUP1 G2BR with UBE2G2 for crystallography

    Depositor

    Allan Weissman

    Article

    Smith et al PLoS Biol. 2021 Dec 8;19(12):e3001474. d

    Insert

    AUP1 aa 379-410, Ube2G2 (AUP1 Human, Mouse)
    

    Use

    Tags

    GST

    Expression

    Bacterial

    Mutation

    Promoter

    Available since

    Feb. 14, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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14. Lenti-sgMroh2b#2/Cre

    Plasmid

    #193220

    Purpose

    Lentiviral vector expressing Cre recombinase (driven by mPGK promoter) and an sgRNA against the mouse Mroh2b gene

    Depositor

    Julien Sage

    Article

    Lee et al Cell Rep. 2023 Jan 13;42(1):111990. doi:

    Insert

    sgMroh2b#2 (Heatr7b2 Mouse)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    U6

    Available since

    Dec. 12, 2022

    Availability

    Academic Institutions and Nonprofits only

    

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15. Lenti-sgMroh2b#1/Cre

    Plasmid

    #193219

    Purpose

    Lentiviral vector expressing Cre recombinase (driven by mPGK promoter) and an sgRNA against the mouse Mroh2b gene

    Depositor

    Julien Sage

    Article

    Lee et al Cell Rep. 2023 Jan 13;42(1):111990. doi:

    Insert

    sgMroh2b#1 (Heatr7b2 Mouse)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    U6

    Available since

    Dec. 9, 2022

    Availability

    Academic Institutions and Nonprofits only

    

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16. pDONR223-ZNF532

    Plasmid

    #88740

    Purpose

    Donor Vector containing ZNF532 transcription factor, part of the Human TFome Collection

    Depositor

    Marc Vidal

    Article

    Ng et al Nat Biotechnol. 2021 Apr;39(4):510-519.

    Insert

    ZNF532 (ZNF532 Human)
    

    Use

    Gateway donor vector

    Tags

    Expression

    Mutation

    Last nucleotide of stop codon removed to allow fo…

    Promoter

    Available since

    March 31, 2022

    Availability

    Academic Institutions and Nonprofits only

17. pDONR223-ZNF77

    Plasmid

    #88744

    Purpose

    Donor Vector containing ZNF77 transcription factor, part of the Human TFome Collection

    Depositor

    Marc Vidal

    Article

    Ng et al Nat Biotechnol. 2021 Apr;39(4):510-519.

    Insert

    ZNF77 (ZNF77 Human)
    

    Use

    Gateway donor vector

    Tags

    Expression

    Mutation

    Last nucleotide of stop codon removed to allow fo…

    Promoter

    Available since

    March 31, 2022

    Availability

    Academic Institutions and Nonprofits only

18. pDONR223-ZNF672

    Plasmid

    #88753

    Purpose

    Donor Vector containing ZNF672 transcription factor, part of the Human TFome Collection

    Depositor

    Marc Vidal

    Article

    Ng et al Nat Biotechnol. 2021 Apr;39(4):510-519.

    Insert

    ZNF672 (ZNF672 Human)
    

    Use

    Gateway donor vector

    Tags

    Expression

    Mutation

    Last nucleotide of stop codon removed to allow fo…

    Promoter

    Available since

    March 31, 2022

    Availability

    Academic Institutions and Nonprofits only

19. pDONR223-ZNF678

    Plasmid

    #88761

    Purpose

    Donor Vector containing ZNF678 transcription factor, part of the Human TFome Collection

    Depositor

    Marc Vidal

    Article

    Ng et al Nat Biotechnol. 2021 Apr;39(4):510-519.

    Insert

    ZNF678 (ZNF678 Human)
    

    Use

    Gateway donor vector

    Tags

    Expression

    Mutation

    Last nucleotide of stop codon removed to allow fo…

    Promoter

    Available since

    March 31, 2022

    Availability

    Academic Institutions and Nonprofits only

20. pDONR223-ZNF688_isoform1

    Plasmid

    #88779

    Purpose

    Donor Vector containing ZNF688 transcription factor, part of the Human TFome Collection

    Depositor

    Marc Vidal

    Article

    Ng et al Nat Biotechnol. 2021 Apr;39(4):510-519.

    Insert

    ZNF688 (ZNF688 Human)
    

    Use

    Gateway donor vector

    Tags

    Expression

    Mutation

    Last nucleotide of stop codon removed to allow fo…

    Promoter

    Available since

    March 31, 2022

    Availability

    Academic Institutions and Nonprofits only