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PAK3 gRNA (BRDN0001148041)

Plasmid

#75678

Purpose

3rd generation lentiviral gRNA plasmid targeting human PAK3

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

PAK3 (PAK3 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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PAK3 gRNA (BRDN0001148181)

Plasmid

#75679

Purpose

3rd generation lentiviral gRNA plasmid targeting human PAK3

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

PAK3 (PAK3 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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PAK3 gRNA (BRDN0001148485)

Plasmid

#75680

Purpose

3rd generation lentiviral gRNA plasmid targeting human PAK3

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

PAK3 (PAK3 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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PRKD1 gRNA (BRDN0001162219)

Plasmid

#77231

Purpose

3rd generation lentiviral gRNA plasmid targeting human PRKD1

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

PRKD1 (PRKD1 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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RIPK2 gRNA (BRDN0001146369)

Plasmid

#76912

Purpose

3rd generation lentiviral gRNA plasmid targeting human RIPK2

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

RIPK2 (RIPK2 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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SH3BP4 gRNA (BRDN0001149529)

Plasmid

#78087

Purpose

3rd generation lentiviral gRNA plasmid targeting human SH3BP4

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

SH3BP4 (SH3BP4 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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SH3BP4 gRNA (BRDN0001487091)

Plasmid

#78089

Purpose

3rd generation lentiviral gRNA plasmid targeting human SH3BP4

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

SH3BP4 (SH3BP4 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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TEK gRNA (BRDN0001146784)

Plasmid

#75722

Purpose

3rd generation lentiviral gRNA plasmid targeting human TEK

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

TEK (TEK Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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TEK gRNA (BRDN0001148973)

Plasmid

#75724

Purpose

3rd generation lentiviral gRNA plasmid targeting human TEK

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

TEK (TEK Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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NRK gRNA (BRDN0001147558)

Plasmid

#76314

Purpose

3rd generation lentiviral gRNA plasmid targeting human NRK

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

NRK (NRK Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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TIE1 gRNA (BRDN0001147382)

Plasmid

#76686

Purpose

3rd generation lentiviral gRNA plasmid targeting human TIE1

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

TIE1 (TIE1 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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MDH1-miR-196b-PGK-GFP-Blast

Plasmid

#31513

Depositor

Chang-Zheng Chen

Article

Arnold et al Genome Res. 2011 May . 21(5):798-810.

Insert

miR-196b (Mir196b Mouse)

Use

Retroviral

Expression

Mammalian

Available Since

Sept. 19, 2011

Availability

Academic Institutions and Nonprofits only
MDH1-miR-324-PGK-GFP-Blas

Plasmid

#31517

Depositor

Chang-Zheng Chen

Article

Arnold et al Genome Res. 2011 May . 21(5):798-810.

Insert

miR-324 (Mir324 Mouse)

Use

Retroviral

Tags

GFP

Expression

Mammalian

Available Since

Sept. 19, 2011

Availability

Academic Institutions and Nonprofits only
MDH1-miR-196a-2-PGK-GFP-Blast

Plasmid

#31511

Depositor

Chang-Zheng Chen

Article

Arnold et al Genome Res. 2011 May . 21(5):798-810.

Insert

miR-196a2 (Mir196a-2 Mouse)

Use

Retroviral

Tags

GFP

Expression

Mammalian

Available Since

Sept. 19, 2011

Availability

Academic Institutions and Nonprofits only
MDH1-miR-196bSM-PGK-GFP-Blast

Plasmid

#31514

Depositor

Chang-Zheng Chen

Article

Arnold et al Genome Res. 2011 May . 21(5):798-810.

Insert

miR-196b (Mir196b Mouse)

Use

Retroviral

Tags

GFP

Expression

Mammalian

Available Since

Sept. 19, 2011

Availability

Academic Institutions and Nonprofits only
SIN-cPPT-G1B3-Gateway-WPRE-miR124T

Plasmid

#245070

Purpose

Gateway cloning with miRNA-124 target sequence to repress transgene expression in neurons

Depositor

Nicole Déglon

Article

Merienne et al Cell Rep. 2017 Sep 19;20(12):2980-2991.

Insert

Gateway

Use

Lentiviral

Expression

Mammalian

Promoter

human GFAP fragments

Available Since

March 19, 2026

Availability

Academic Institutions and Nonprofits only

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pEMS2367

Plasmid

#225636

Purpose

High Copy number plasmid containing Ple384 (TH MiniPromoter) insert

Depositor

Elizabeth Simpson

Article

Galvan et al Sci Rep. 2026 Feb 16. doi: 10.1038/s4159

Insert

Ple384 (TH Human)

Use

Unspecified

Available Since

Feb. 5, 2026

Availability

Academic Institutions and Nonprofits only

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pYPQ133B-TLS-CsALSgR1.2

Plasmid

#245878

Purpose

Golden gate entry vector carrying the 2nd gRNA for base editing in Carrizo citrange ALS gene along with TLS mobile RNA sequence

Depositor

Yiping Qi

Article

Rocha et al Plant Cell Rep. 2025 Oct 22;44(11):244.

Insert

CsALSgR1.2

Use

CRISPR; Golden gate entry vector

Expression

Plant

Promoter

AtU3

Available Since

Feb. 2, 2026

Availability

Academic Institutions and Nonprofits only

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pYPQ132B-CsALSgR1.1

Plasmid

#245875

Purpose

Golden gate entry vector carrying the 1st gRNA for base editing in Carrizo citrange ALS gene

Depositor

Yiping Qi

Article

Rocha et al Plant Cell Rep. 2025 Oct 22;44(11):244.

Insert

CsALS_gRNA1.1

Use

CRISPR; Golden gate entry vector to expressing t…

Expression

Plant

Promoter

AtU3

Available Since

Feb. 2, 2026

Availability

Academic Institutions and Nonprofits only

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pLenti Blast GRP94 WT V5

Plasmid

#240446

Purpose

Expresses GRP94 in mammalian cells

Depositor

Michael Kastan

Article

Burrell et al Proc Natl Acad Sci U S A. 2025 Dec 30;12

Insert

GRP94 (HSP90B1 Human)

Use

Lentiviral

Tags

V5 tag and second KDEL sequence

Expression

Mammalian

Promoter

CMV

Available Since

Feb. 2, 2026

Availability

Academic Institutions and Nonprofits only

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