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TRBV29-1

Plasmid

#237949

Purpose

Encodes TRBV29-1 allele and TRAC to generate TCRs via cloning

Depositor

Michael Birnbaum

Article

Gaglione et al Immunity. 2026 Feb 10;59(2):477-493.e9.

Insert

TRBV29-1-TRAC (TRBV29-1 Human)

Use

Synthetic Biology

Mutation

None

Available Since

Sept. 16, 2025

Availability

Academic Institutions and Nonprofits only

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TRBV5-1

Plasmid

#237908

Purpose

Encodes TRBV5-1 allele and TRAC to generate TCRs via cloning

Depositor

Michael Birnbaum

Article

Gaglione et al Immunity. 2026 Feb 10;59(2):477-493.e9.

Insert

TRBV5-1-TRAC (TRBV5-1 Human)

Use

Synthetic Biology

Mutation

None

Available Since

Sept. 16, 2025

Availability

Academic Institutions and Nonprofits only

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TRBV19

Plasmid

#237943

Purpose

Encodes TRBV19 allele and TRAC to generate TCRs via cloning

Depositor

Michael Birnbaum

Article

Gaglione et al Immunity. 2026 Feb 10;59(2):477-493.e9.

Insert

TRBV19-TRAC (TRBV19 Human)

Use

Synthetic Biology

Mutation

None

Available Since

Sept. 16, 2025

Availability

Academic Institutions and Nonprofits only

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TRBV25-1

Plasmid

#237946

Purpose

Encodes TRBV25-1 allele and TRAC to generate TCRs via cloning

Depositor

Michael Birnbaum

Article

Gaglione et al Immunity. 2026 Feb 10;59(2):477-493.e9.

Insert

TRBV25-1-TRAC (TRBV25-1 Human)

Use

Synthetic Biology

Mutation

None

Available Since

Sept. 16, 2025

Availability

Academic Institutions and Nonprofits only

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TRBV6-6

Plasmid

#237918

Purpose

Encodes TRBV6-6 allele and TRAC to generate TCRs via cloning

Depositor

Michael Birnbaum

Article

Gaglione et al Immunity. 2026 Feb 10;59(2):477-493.e9.

Insert

TRBV6-6-TRAC (TRBV6-6 Human)

Use

Synthetic Biology

Mutation

None

Available Since

Sept. 16, 2025

Availability

Academic Institutions and Nonprofits only

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TRBV7-6

Plasmid

#237924

Purpose

Encodes TRBV7-6 allele and TRAC to generate TCRs via cloning

Depositor

Michael Birnbaum

Article

Gaglione et al Immunity. 2026 Feb 10;59(2):477-493.e9.

Insert

TRBV7-6-TRAC (TRBV7-6 Human)

Use

Synthetic Biology

Mutation

None

Available Since

Sept. 16, 2025

Availability

Academic Institutions and Nonprofits only

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TRAV1-1

Plasmid

#237951

Purpose

Encodes TRAV1-1 allele, P2A, and TRBC to generate TCRs via cloning

Depositor

Michael Birnbaum

Article

Gaglione et al Immunity. 2026 Feb 10;59(2):477-493.e9.

Insert

TRBC-P2A-TRAV1-1 (TRAV1-1 Human)

Use

Synthetic Biology

Mutation

None

Available Since

Sept. 16, 2025

Availability

Academic Institutions and Nonprofits only

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Mirror GFP[ENE(C8351G)-mascRNA](pAVA3000)

Plasmid

#239349

Purpose

Expresses TEV protease and tandemly-repeated GFP fluorescent proteins to amplify the fluorescence signal produced by a single transcription unit of C8351G MALAT1 ENE-mascRNA reporter.

Depositor

Andrei Alexandrov

Article

Che et al Nat Commun. 2025 May 22;16(1):4741. doi:

Insert

MALAT1 ENE(C8351G)-mascRNA

Expression

Mammalian

Mutation

MALAT1 ENE(C8351G)

Available Since

Aug. 26, 2025

Availability

Academic Institutions and Nonprofits only

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pCS2+8-CYP2A6(C14A, C82A, C439A)-flag-tev-halo-his

Plasmid

#227164

Purpose

For T-REX experiments of CYP2A6 C14A, C82A, and C439A triple mutant. Almost no sensing ability to reactive electrophilic species (RES).

Depositor

Yimon Aye

Article

Liu et al Cell. 2024 Dec 26;187(26):7450-7469.e29.

Insert

CYP2A6 (CYP2A6 Human)

Tags

Flag, HaloTag, and His6

Expression

Mammalian

Mutation

changed cysteine 14, cysteine 82, and cysteine 43…

Promoter

CMV and SP6

Available Since

Aug. 19, 2025

Availability

Academic Institutions and Nonprofits only

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Mirror RFP[ENE(C8351G)-mascRNA](pAVA2995)

Plasmid

#239350

Purpose

Expresses TEV protease and tandemly-repeated RFP fluorescent proteins to amplify the fluorescence signal produced by a single transcription unit of C8351G MALAT1 ENE-mascRNA reporter.

Depositor

Andrei Alexandrov

Article

Che et al Nat Commun. 2025 May 22;16(1):4741. doi:

Insert

MALAT1 ENE(C8351G)-mascRNA

Expression

Mammalian

Mutation

MALAT1 ENE(C8351G)

Available Since

Aug. 15, 2025

Availability

Academic Institutions and Nonprofits only

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LentiCRISPR-B_sgRNA_POP1 (pAVA3497)

Plasmid

#239311

Purpose

Lentiviral vector expressing Cas9-P2A-Blasticidin and an sgRNA targeting POP1

Depositor

Andrei Alexandrov

Article

Che et al Nat Commun. 2025 May 22;16(1):4741. doi:

Insert

U6-driven sgRNA targeting POP1 (POP1 Human)

Use

CRISPR and Lentiviral

Available Since

Aug. 4, 2025

Availability

Academic Institutions and Nonprofits only

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LentiCRISPR-B_sgRNA_RPP38 (pAVA3523)

Plasmid

#239313

Purpose

Lentiviral vector expressing Cas9-P2A-Blasticidin and an sgRNA targeting RPP38

Depositor

Andrei Alexandrov

Article

Che et al Nat Commun. 2025 May 22;16(1):4741. doi:

Insert

U6-driven sgRNA targeting RPP38 (RPP38 Human)

Use

CRISPR and Lentiviral

Available Since

Aug. 4, 2025

Availability

Academic Institutions and Nonprofits only

Enlarge
LentiCRISPR-B_sgRNA_RPP29 (pAVA3545)

Plasmid

#239314

Purpose

Lentiviral vector expressing Cas9-P2A-Blasticidin and an sgRNA targeting RPP29

Depositor

Andrei Alexandrov

Article

Che et al Nat Commun. 2025 May 22;16(1):4741. doi:

Insert

U6-driven sgRNA targeting RPP29 (POP4 Human)

Use

CRISPR and Lentiviral

Available Since

Aug. 4, 2025

Availability

Academic Institutions and Nonprofits only

Enlarge
LentiCRISPR-B_sgRNA_POP5 (pAVA3498)

Plasmid

#239315

Purpose

Lentiviral vector expressing Cas9-P2A-Blasticidin and an sgRNA targeting POP5

Depositor

Andrei Alexandrov

Article

Che et al Nat Commun. 2025 May 22;16(1):4741. doi:

Insert

U6-driven sgRNA targeting POP5 (POP5 Human)

Use

CRISPR and Lentiviral

Available Since

Aug. 4, 2025

Availability

Academic Institutions and Nonprofits only

Enlarge
LentiCRISPR-B_sgRNA_RPP20 (pAVA3546)

Plasmid

#239316

Purpose

Lentiviral vector expressing Cas9-P2A-Blasticidin and an sgRNA targeting RPP20

Depositor

Andrei Alexandrov

Article

Che et al Nat Commun. 2025 May 22;16(1):4741. doi:

Insert

U6-driven sgRNA targeting RPP20 (POP7 Human)

Use

CRISPR and Lentiviral

Available Since

Aug. 4, 2025

Availability

Academic Institutions and Nonprofits only

Enlarge
LentiCRISPR-B_sgRNA_RPP14 (pAVA3507)

Plasmid

#239317

Purpose

Lentiviral vector expressing Cas9-P2A-Blasticidin and an sgRNA targeting RPP14

Depositor

Andrei Alexandrov

Article

Che et al Nat Commun. 2025 May 22;16(1):4741. doi:

Insert

U6-driven sgRNA targeting RPP14 (RPP14 Human)

Use

CRISPR and Lentiviral

Available Since

Aug. 4, 2025

Availability

Academic Institutions and Nonprofits only

Enlarge
LentiCRISPR-B_sgRNA_RPP30 (pAVA3573)

Plasmid

#239318

Purpose

Lentiviral vector expressing Cas9-P2A-Blasticidin and an sgRNA targeting RPP30

Depositor

Andrei Alexandrov

Article

Che et al Nat Commun. 2025 May 22;16(1):4741. doi:

Insert

U6-driven sgRNA targeting RPP30 (RPP30 Human)

Use

CRISPR and Lentiviral

Available Since

Aug. 4, 2025

Availability

Academic Institutions and Nonprofits only

Enlarge
LentiCRISPR-B_sgRNA_RPP40 (pAVA3540)

Plasmid

#239319

Purpose

Lentiviral vector expressing Cas9-P2A-Blasticidin and an sgRNA targeting RPP40

Depositor

Andrei Alexandrov

Article

Che et al Nat Commun. 2025 May 22;16(1):4741. doi:

Insert

U6-driven sgRNA targeting RPP40 (RPP40 Human)

Use

CRISPR and Lentiviral

Available Since

Aug. 4, 2025

Availability

Academic Institutions and Nonprofits only

Enlarge
LentiCRISPR-B_sgRNA_RPP25 (pAVA3522)

Plasmid

#239320

Purpose

Lentiviral vector expressing Cas9-P2A-Blasticidin and an sgRNA targeting RPP25

Depositor

Andrei Alexandrov

Article

Che et al Nat Commun. 2025 May 22;16(1):4741. doi:

Insert

U6-driven sgRNA targeting RPP25 (RPP25 Human)

Use

CRISPR and Lentiviral

Available Since

Aug. 4, 2025

Availability

Academic Institutions and Nonprofits only

Enlarge
LentiCRISPR-B_sgRNA_RPP25L (pAVA3548)

Plasmid

#239321

Purpose

Lentiviral vector expressing Cas9-P2A-Blasticidin and an sgRNA targeting RPP25L

Depositor

Andrei Alexandrov

Article

Che et al Nat Commun. 2025 May 22;16(1):4741. doi:

Insert

U6-driven sgRNA targeting RPP25L (RPP25L Human)

Use

CRISPR and Lentiviral

Available Since

Aug. 4, 2025

Availability

Academic Institutions and Nonprofits only

Enlarge