We narrowed to 32,294 results for: IND;

1. LT3GEPIR-ARshRNA3

   Plasmid

   #220563

   Purpose

   To inducibly knockdown AR expression

   Depositor

   Sean Lee

   Article

   Magrath et al Commun Biol. 2024 Apr 4;7(1):411. doi: 1

   Insert

   AR shRNA3 (AR Human)
   

   Use

   Lentiviral

   Tags

   Expression

   Mutation

   Promoter

   TRE3G (TetOP) promoter

   Available since

   July 1, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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2. LT3GEPIR-ARshRNA4

   Plasmid

   #220564

   Purpose

   To inducibly knockdown AR expression

   Depositor

   Sean Lee

   Article

   Magrath et al Commun Biol. 2024 Apr 4;7(1):411. doi: 1

   Insert

   AR shRNA4 (AR Human)
   

   Use

   Lentiviral

   Tags

   Expression

   Mutation

   Promoter

   TRE3G (TetOP) promoter

   Available since

   July 1, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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3. lenti-EGFR-L858R-T790M-dual-nick sgRNA

   Plasmid

   #214101

   Purpose

   Lentiviral vector expressing nicking sgRNAs for the induction of EGFR L858R and T790M mutations, through tandem U6 expression of the two sgRNAs using independent U6 promoters.

   Depositor

   Ting Zhou

   Article

   Wu et al Nat Commun. 2024 Dec 30;15(1):10824. doi

   Insert

   EGFR L858R nicking sgRNA/EGFR T790M nicking sgRNA
   

   Use

   Lentiviral

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   hU6

   Available since

   June 6, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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4. pMeCP2Y pc644

   Plasmid

   #167565

   Purpose

   The complete rat MeCp2 ORF is fused in frame of the NH2-terminus of the enhanced YFP (pEYFP-N1 vector; CLONTECH Laboratories, Inc.)

   Depositor

   Cristina Cardoso

   Article

   Brero et al J Cell Biol. 2005 Jun 6;169(5):733-43. d

   Insert

   Methyl-CpG binding protein 2 (Mecp2 Rat)
   

   Use

   Tags

   YFP

   Expression

   Mammalian

   Mutation

   Promoter

   CMV

   Available since

   March 8, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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5. pCas-pML-1B_6xHis-Cas12m

   Plasmid

   #192282

   Purpose

   MmCas12m fused to His-tag for protein purification

   Depositor

   John van der Oost

   Article

   Wu et al Mol Cell. 2022 Dec 1;82(23):4487-4502.e7

   Insert

   MmCas12m
   

   Use

   CRISPR

   Tags

   His-tag

   Expression

   Bacterial

   Mutation

   Promoter

   T7

   Available since

   May 24, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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6. pESF140_HisSpy_DDB1∆B

   Plasmid

   #124213

   Purpose

   Insect cell expression vector for His6, Spy tagged hsDDB1∆B

   Depositor

   Eric Fischer

   Article

   Nowak et al Nat Chem Biol. 2018 Jul;14(7):706-714. d

   Insert

   DNA damage-binding protein 1 (DDB1 Human)
   

   Use

   Tags

   His6-Spy

   Expression

   Insect

   Mutation

   internal deletion of BPB domain to aid crystalliz…

   Promoter

   Available since

   April 16, 2019

   Availability

   Academic Institutions and Nonprofits only

   

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7. pETDuet-1 TIM9,10

   Plasmid

   #170280

   Purpose

   Expresses both yeast Tim9 and yeast Tim10 (the latter with cleavable N-ter His-tag), codon-optimized for E. coli production

   Depositor

   Paul Schanda

   Article

   Weinhaupl et al Cell. 2018 Nov 15;175(5):1365-1379.e25.

   Insert

   mitochondrial Tim9 chaperone subunit and Tim10 (with N-ter His tag) (TIM9, TIM10 Budding Yeast)
   

   Use

   Tags

   Expression

   Bacterial

   Mutation

   Promoter

   Tim9: via NdeI/XhoI into the MCS2; Tim10: via Bam…

   Available since

   June 15, 2021

   Availability

   Academic Institutions and Nonprofits only

   

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8. pT3-EF1aH-TAZ S89A

   Plasmid

   #179910

   Purpose

   Construct for expressing an activated form of TAZ (encoding be gene WWTR1)

   Depositor

   Xin Chen

   Article

   Wang et al J Hepatol. 2021 Aug 28. pii: S0168-8278(

   Insert

   WW Domain Containing Transcription Regulator 1 (WWTR1 Human)
   

   Use

   Tags

   3X Flag-tag

   Expression

   Mammalian

   Mutation

   Serine 89 mutated to Alanine

   Promoter

   EF1a

   Available since

   April 21, 2022

   Availability

   Academic Institutions and Nonprofits only

   

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9. pLVX MLKL(wt)--2A-mCherry-puro

   Plasmid

   #231974

   Purpose

   Tet inducible expression of DmrB-Mlkl with mCherry to induce WT Mlkl expression

   Depositor

   Brian Ruffell

   Article

   Hanggi et al Cancer Cell. 2024 Nov 13:S1535-6108(24)0

   Insert

   MLKL WT construct with bi-cistronic mCherry (Mlkl Mouse)
   

   Use

   Lentiviral

   Tags

   Expression

   Mutation

   WT

   Promoter

   Available since

   Feb. 5, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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10. pcDNA3.1 His-GFP-EWSR1-myc-His

    Plasmid

    #46385

    Purpose

    expresses EGFP tagged EWSR1 in mammalian cells

    Depositor

    Heinz Gehring

    Article

    Pahlich et al Proteins. 2008 Sep;72(4):1125-37. doi: 1

    Insert

    EWSR1 (EWSR1 Human)
    

    Use

    Tags

    EGFP, His, and myc

    Expression

    Mammalian

    Mutation

    Promoter

    CMV

    Available since

    Sept. 5, 2013

    Availability

    Academic Institutions and Nonprofits only

11. pDONR221_SLC13A5

    Plasmid

    #131945

    Purpose

    Gateway entry clone with codon-optimized ORF sequence for subcloning into custom expression vectors

    Depositor

    RESOLUTE Consortium, Giulio Superti-Furga

    Article

    Superti-Furga et al Nat Rev Drug Discov. 2020 Jul;19(7):429-

    Insert

    SLC13A5 (SLC13A5 Human)
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    Oct. 17, 2019

    Availability

    Industry, Academic Institutions, and Nonprofits

    

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12. pcDNA3HA-AR-LBD

    Plasmid

    #89111

    Purpose

    mammalian expression of human androgen receptor ligand binding domain amino acid residues 624-919 with N-terminal double HA tag

    Depositor

    Elizabeth Wilson

    Article

    He et al J Biol Chem. 1999 Dec 24;274(52):37219-2

    Insert

    hAR ligand binding domain (AR Human)
    

    Use

    Tags

    2xHA

    Expression

    Mammalian

    Mutation

    contains Ligand Binding Domain (624-919)

    Promoter

    CMV

    Available since

    April 11, 2017

    Availability

    Academic Institutions and Nonprofits only

    

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13. pcDNA3-GFP-IMP2-2_antisense-control

    Plasmid

    #42174

    Depositor

    Alexandra Kiemer

    Article

    Kessler et al Am J Physiol Gastrointest Liver Physiol.

    Insert

    Insulin-like growth factor 2 mRNA binding protein 2-2 antisense control (IGF2BP2 Human)
    

    Use

    Tags

    GFP

    Expression

    Mammalian

    Mutation

    Promoter

    T7

    Available since

    June 14, 2013

    Availability

    Academic Institutions and Nonprofits only

14. pGL2-Mcl-1 mut

    Plasmid

    #19133

    Depositor

    Wafik El-Deiry

    Article

    Ricci et al Cancer Cell. 2007 Jul . 12(1):66-80.

    Insert

    Mcl-1 promoter (MCL1 Human)
    

    Use

    Luciferase

    Tags

    Expression

    Mammalian

    Mutation

    NFkB binding-site mutant, the sequence GGGGTCTTCC…

    Promoter

    Available since

    Oct. 2, 2008

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

15. CMV-FFluc-GPD1L-3'UTR Full mut

    Plasmid

    #32489

    Depositor

    Pere Puigserver

    Article

    Kelly et al Mol Cell Biol. 2011 Jul;31(13):2696-706.

    Insert

    GPD1L 3'UTR (Gpd1l Mouse)
    

    Use

    Tags

    Luciferase

    Expression

    Mammalian

    Mutation

    Mutated in the entire miR-210 binding region

    Promoter

    CMV

    Available since

    Nov. 4, 2011

    Availability

    Academic Institutions and Nonprofits only

16. pMeCP2G pc1121

    Plasmid

    #167566

    Purpose

    The complete rat MeCp2 ORF is fused in frame of the NH2-terminus of the enhanced GFP (isolated from pEGFP-N1 vector; CLONTECH Laboratories, Inc.)

    Depositor

    Cristina Cardoso

    Article

    Brero et al J Cell Biol. 2005 Jun 6;169(5):733-43. d

    Inserts

    Methyl-CpG binding protein 2 (Mecp2 Rat)
    GFP
    

    Use

    Tags

    GFP

    Expression

    Mammalian

    Mutation

    Promoter

    CMV

    Available since

    March 8, 2023

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

17. HA-HA-AR-DBD-LBD

    Plasmid

    #171237

    Purpose

    Mammalian expression of 2xHA-tagged human androgen receptor trancate: AR DNA-bindind domain and Ligand-binding domain (DBD-LBD)

    Depositor

    Steven Balk

    Article

    Liu et al Oncotarget. 2016 Jan 12;7(2):1754-64. do

    Insert

    2xHA-tagged human androgen receptor trancate:DNA-binding domain and Ligand-binding domain (AR Human)
    

    Use

    Tags

    HA

    Expression

    Bacterial and Mammalian

    Mutation

    AR truncate

    Promoter

    CMV

    Available since

    June 25, 2021

    Availability

    Academic Institutions and Nonprofits only

    

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18. pLVX-DmrB-DmrB-Ripk3-2A-mCherry-puro

    Plasmid

    #231972

    Purpose

    Tet inducible expression of DmrB-Ripk3 with mCherry to induce Ripk3 necroptosis

    Depositor

    Brian Ruffell

    Article

    Hanggi et al Cancer Cell. 2024 Nov 13:S1535-6108(24)0

    Insert

    Ripk3-deltaC dimerizing construct with bi-cistronic mCherry (Ripk3 Mouse)
    

    Use

    Lentiviral

    Tags

    Expression

    Mutation

    WT

    Promoter

    Available since

    Feb. 5, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

19. pGS_128

    Plasmid

    #160651

    Purpose

    Expresses Human APOE3 with a yeast secretory signal peptide under the control of a beta-estradiol inducible promoter

    Depositor

    Li-Huei Tsai, Susan Lindquist

    Article

    Sienski et al Sci Transl Med. 2021 Mar 3;13(583). pii:

    Insert

    Apolipoprotein E e3 (APOE Human)
    

    Use

    Tags

    Kar2 signal sequence

    Expression

    Yeast

    Mutation

    e3 allele

    Promoter

    pZ estradiol inducible promoter

    Available since

    Jan. 4, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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20. pRetroX GFP Mps1 wt

    Plasmid

    #63702

    Purpose

    Inducible expression of GFP-Mps1 fusion in mammalian cells

    Depositor

    Floris Foijer

    Article

    Foijer et al Proc Natl Acad Sci U S A. 2014 Sep 16;11

    Insert

    Mps1 (TTK Human)
    

    Use

    Retroviral

    Tags

    EGFP

    Expression

    Mammalian

    Mutation

    Promoter

    tight TRE promoter

    Available since

    April 22, 2015

    Availability

    Academic Institutions and Nonprofits only

    

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