Purpose
destabilizing domains for yeast (S. cerevisiae) derived from the human estrogen receptor ligand binding domain. This ERdd can be stabilized with 10 uM 4-hydroxytamoxifen (4-OHT, OHTAM).
Insert
ER50 (
ESR1 H. sapiens gene with yeast enhanced codon)
Tags
yeast enhanced GFP with 8 amino acids TSGRGEGQ li…
Mutation
3 mutations : E380G, R434G, N532S
Available Since
April 26, 2018
Availability
Academic Institutions and Nonprofits only