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pTYB3-human PUM1-HD PUF531_Q867E-Q939E-C935S-Q1011E- C1007S-intein-CBD

Plasmid

#73306

Purpose

Expresses mutant human PUM1-HD

Depositor

Traci Hall

Article

Wang et al Nat Methods. 2009 Nov;6(11):825-30. doi:

Insert

human PUM1 Pumilio homology domain (PUM1 Human)

Tags

intein

Expression

Bacterial

Mutation

Q867E-Q939E-C935S-Q1011E-C1007S

Available Since

Feb. 24, 2016

Availability

Academic Institutions and Nonprofits only
pET28A-p53 (1-73) (P27A)

Plasmid

#62068

Purpose

Expression of human p53 (1-73) (P27A) in e. coli

Depositor

Gary Daughdrill

Article

Borcherds et al Nat Chem Biol. 2014 Dec;10(12):1000-2. d

Insert

p53 (TP53 Human)

Tags

His

Expression

Bacterial

Mutation

Contains TAD residues 1-73; P27A

Promoter

T7

Available Since

Jan. 28, 2015

Availability

Academic Institutions and Nonprofits only
pCMV-Tag4A-MMP8 (G104R)

Plasmid

#29548

Depositor

Yardena Samuels

Article

Palavalli et al Nat Genet. 2009 May . 41(5):518-20.

Insert

Metalloproteinase protein 8 (MMP8 Human)

Tags

FLAG

Expression

Bacterial and Mammalian

Mutation

G104R

Available Since

July 22, 2011

Availability

Academic Institutions and Nonprofits only
pDONR221-hSOX10-C373T

Plasmid

#24734

Depositor

William Pavan

Article

Cronin et al Pigment Cell Melanoma Res. 2009 Aug . 22

Insert

(sex determining region Y)-box 10 (SOX10 Human)

Use

Gateway donor vector

Mutation

C replaced by T at position 373 resulting in Q125…

Available Since

June 18, 2010

Availability

Academic Institutions and Nonprofits only
pDONR221-hSOX10-C1271T

Plasmid

#24736

Depositor

William Pavan

Article

Cronin et al Pigment Cell Melanoma Res. 2009 Aug . 22

Insert

(sex determining region Y)-box 10 (SOX10 Human)

Use

Gateway donor vector

Mutation

C replaced with T at position 1271 resulting in A…

Available Since

May 18, 2010

Availability

Academic Institutions and Nonprofits only
pCMV-ePiv (CJT553)

Plasmid

#248215

Purpose

ePiv invertase, expressed from a CMV promoter.

Depositor

Benjamin Kleinstiver

Article

Tou et al Nature. 2026 Mar 11. doi: 10.1038/s41586

Insert

ePiv invertase

Use

CRISPR; In vitro transcription

Expression

Mammalian

Mutation

ePiv(E257R, E285R, T290R)

Promoter

CMV and T7

Available Since

April 16, 2026

Availability

Academic Institutions and Nonprofits only

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pCMV-bpNLS-IS621 (CJT489)

Plasmid

#248213

Purpose

bpNLS-tagged IS621 bridge recombinase, expressed from a CMV promoter.

Depositor

Benjamin Kleinstiver

Article

Tou et al Nature. 2026 Mar 11. doi: 10.1038/s41586

Insert

bpNLS-IS621

Use

CRISPR; In vitro transcription

Tags

BPNLS

Expression

Mammalian

Mutation

None

Promoter

CMV and T7

Available Since

April 16, 2026

Availability

Academic Institutions and Nonprofits only

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pCMV-bpNLS-Bxb1 (EMK569)

Plasmid

#248208

Purpose

Bxb1 recombinase with N-terminal bpNLS, expressed from a CMV promoter.

Depositor

Benjamin Kleinstiver

Article

Tou et al Nature. 2026 Mar 11. doi: 10.1038/s41586

Insert

bpNLS-Bxb1

Use

CRISPR; In vitro transcription

Tags

BPNLS

Expression

Mammalian

Mutation

None

Promoter

CMV and T7

Available Since

April 15, 2026

Availability

Academic Institutions and Nonprofits only

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AAV-tsC2ProT-mScarlet3-Cre

Plasmid

#248522

Purpose

This vector co-expresses Red Fluorescent Protein mScarlet3 and Cre Recombinase under the control of the truncated Tree Shrew Cerebellin 2 Promoter.

Depositor

Alev Erisir

Article

Kipcak et al Cell Rep Methods. 2026 Mar 23;6(3):10130

Insert

Truncated Tree Shrew Cerebellin 2 Promoter + mScarlet3 + Cre

Use

AAV

Expression

Mammalian

Promoter

Truncated Tree shrew Cerebellin 2 Promoter

Available Since

March 4, 2026

Availability

Academic Institutions and Nonprofits only

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pAG8Ha-His-PPIL1

Plasmid

#237554

Purpose

E. coli recombinant protein expression

Depositor

David Libich

Article

Parra et al Biochemistry. 2025 Aug 5;64(15):3173-317

Insert

Peptidyl-prolyl cis-trans isomerase-like 1 (PPIL1 Human)

Tags

8xHis - TEV cleavage site

Expression

Bacterial

Promoter

T7

Available Since

Feb. 3, 2026

Availability

Industry, Academic Institutions, and Nonprofits

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pLJC2-HK2-3xFLAG

Plasmid

#239243

Purpose

HK2 lentiviral overexpression vector

Depositor

Jason Cantor

Article

Huggler et al Nat Metab. 2026 Jan 16. doi: 10.1038/s42

Insert

HK2 (HK2 Human)

Use

Lentiviral

Tags

3xFLAG

Expression

Mammalian

Mutation

Insert contains silent mutations introduced to ab…

Promoter

CMV

Available Since

Jan. 26, 2026

Availability

Academic Institutions and Nonprofits only

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pLJC5-HK1-3xFLAG

Plasmid

#239247

Purpose

HK1 lentiviral overexpression vector

Depositor

Jason Cantor

Article

Huggler et al Nat Metab. 2026 Jan 16. doi: 10.1038/s42

Insert

HK1 (HK1 Human)

Use

Lentiviral

Tags

3xFLAG

Expression

Mammalian

Mutation

Insert contains the following silent mutations (c…

Promoter

Ubc

Available Since

Jan. 26, 2026

Availability

Academic Institutions and Nonprofits only

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pLJC6-HK2 (D209A, D657A)-3xFLAG

Plasmid

#239251

Purpose

HK2 lentiviral overexpression vector

Depositor

Jason Cantor

Article

Huggler et al Nat Metab. 2026 Jan 16. doi: 10.1038/s42

Insert

HK2 (HK2 Human)

Use

Lentiviral

Tags

3xFLAG

Expression

Mammalian

Mutation

Insert contains the set of silent mutations descr…

Promoter

Ubc

Available Since

Jan. 26, 2026

Availability

Academic Institutions and Nonprofits only

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pLJC6-HK1-3xFLAG

Plasmid

#239252

Purpose

HK1 lentiviral overexpression vector

Depositor

Jason Cantor

Article

Huggler et al Nat Metab. 2026 Jan 16. doi: 10.1038/s42

Insert

HK1 (HK1 Human)

Use

Lentiviral

Tags

3xFLAG

Expression

Mammalian

Mutation

Insert contains the set of silent mutations descr…

Promoter

Ubc

Available Since

Jan. 26, 2026

Availability

Academic Institutions and Nonprofits only

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pLJC6-HK2 (delta MBD)-3xFLAG

Plasmid

#239254

Purpose

HK2 lentiviral overexpression vector

Depositor

Jason Cantor

Article

Huggler et al Nat Metab. 2026 Jan 16. doi: 10.1038/s42

Insert

HK2 (HK2 Human)

Use

Lentiviral

Tags

3xFLAG

Expression

Mammalian

Mutation

Insert contains the set of silent mutations descr…

Promoter

Ubc

Available Since

Jan. 26, 2026

Availability

Academic Institutions and Nonprofits only

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pLJC6-MBD1-HK2-3xFLAG

Plasmid

#239255

Purpose

HK2 lentiviral overexpression vector

Depositor

Jason Cantor

Article

Huggler et al Nat Metab. 2026 Jan 16. doi: 10.1038/s42

Insert

HK2 (HK2 Human)

Use

Lentiviral

Tags

3xFLAG

Expression

Mammalian

Mutation

Insert contains the set of silent mutations descr…

Promoter

Ubc

Available Since

Jan. 26, 2026

Availability

Academic Institutions and Nonprofits only

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Topo_SpCas9.tracrRNA-CS1_AsCas12a DRv10

Plasmid

#237553

Purpose

TOPO vector for the cloning of the SpCas9 tracrRNA-CS1 - AsCas12a Direct Repeat (DR) v10 fragment into the pLCHKO_v4 hgRNA vector for scCHyMErA-Seq experiments.

Depositor

Thomas Gonatopoulos-Pournatzis

Article

Kumari et al Nat Commun. 2026 Feb 3;17(1):1218. doi:

Insert

SpCas9.tracrRNA-CS1_AsCas12a DRv10

Use

CRISPR

Available Since

Jan. 12, 2026

Availability

Academic Institutions and Nonprofits only

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pcDNA5-miniTurbo-NRF1-FL

Plasmid

#237453

Purpose

Vector for generating Flp-In cell lines allowing dox-inducible mammalian expression of miniTurbo fused to full-length NRF1 isoform

Depositor

Thomas Gonatopoulos-Pournatzis

Article

Kumari et al Nat Commun. 2026 Feb 3;17(1):1218. doi:

Insert

NRF1 full length

Tags

miniTurbo

Expression

Mammalian

Promoter

CMV/TO inducible promoter

Available Since

Jan. 12, 2026

Availability

Academic Institutions and Nonprofits only

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FUGW-EGFP-mHif1a-T163A

Plasmid

#242810

Purpose

Lentiviral vector expressing mouse Hif1a-T163A mutant tagged with an N-terminal EGFP

Depositor

Ronald Hart

Article

Sun et al Nat Commun. 2025 Oct 21;16(1):9312. doi:

Insert

Hypoxia-inducible factor 1, alpha subunit (Hif1a Mouse)

Use

Lentiviral

Tags

EGFP

Mutation

T163A

Promoter

Ubiquitin C

Available Since

Dec. 17, 2025

Availability

Academic Institutions and Nonprofits only

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pLenti-ZNF207-3xFLAG

Plasmid

#231939

Purpose

Vector for generating stable lines allowing expression of ZNF207-3xFLAG

Depositor

Thomas Gonatopoulos-Pournatzis

Article

Behera et al Mol Cell. 2026 Jan 8;86(1):41-59.e15. do

Insert

ZNF207 (ZNF207 Human)

Use

Lentiviral

Tags

FLAG

Promoter

CMV

Available Since

Dec. 12, 2025

Availability

Academic Institutions and Nonprofits only

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