We narrowed to 1,373 results for: tox

1. pSIREN-RetroQ-BPTF-sh5

   Plasmid

   #83045

   Purpose

   MMLV LTR plasmid pSIREN-RetroQ-BPTF-sh5

   Depositor

   Joe Landry

   Article

   Mayes et al Oncotarget. 2017 May 12;8(38):64344-6435

   Insert

   shRNA #5 to BPTF (BPTF, Bptf Human, Mouse)
   

   Use

   Retroviral

   Tags

   Expression

   Mutation

   Promoter

   Available since

   Oct. 24, 2016

   Availability

   Industry, Academic Institutions, and Nonprofits

   

   Enlarge

2. pBABE-Tau-cYFP

   Plasmid

   #92205

   Purpose

   Retroviral overexpression vector for α-Syn/Tau bimolecular fluorescence complementation (BiFC)

   Depositor

   Huda Zoghbi

   Article

   Rousseaux et al Elife. 2016 Oct 25;5. pii: e19809. doi:

   Insert

   MAPT (MAPT Human)
   

   Use

   Retroviral

   Tags

   YFP(156-239)

   Expression

   Mammalian

   Mutation

   Promoter

   Available since

   Aug. 7, 2017

   Availability

   Academic Institutions and Nonprofits only

3. pAAV hSyn mCh-IRES-SspB(milli)-BoNT/B(147-441, Y365A)

   Plasmid

   #122985

   Purpose

   AAV plasmid with human synapsin promoter driving mCh and SspB(milli)-BoNT/B amino acids 147-441 separated with an IRES element. Co-express with BoNT/B(1-146)-iLID construct for PA-BoNT

   Depositor

   Matthew Kennedy

   Article

   Liu et al Neuron. 2019 Jan 15. pii: S0896-6273(19)

   Insert

   mCh-IRES-SspB(milli)-BoNT/B(147-441)
   

   Use

   AAV

   Tags

   mCh

   Expression

   Mammalian

   Mutation

   SspB contains A58V,R73Q "milli" mutatio…

   Promoter

   human synapsin

   Available since

   March 20, 2019

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

4. pAAV hSyn syph-GFP-myc-BoNT/B(1-146)-iLID

   Plasmid

   #122981

   Purpose

   AAV plasmid with human synapsin promoter driving synaptophysin fused to GFP, iLID(V416I) and BoNT/B amino acids 1-146. Co-express with SSPB-BoNT(147-441, Y365A) for vPA-BoNT

   Depositor

   Matthew Kennedy

   Article

   Liu et al Neuron. 2019 Jan 15. pii: S0896-6273(19)

   Insert

   Syph-GFP-myc-BoNT/B(1-146)-iLID (Syp Rat, Synthetic)
   

   Use

   AAV

   Tags

   GFP

   Expression

   Mammalian

   Mutation

   Promoter

   human synapsin

   Available since

   March 19, 2019

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

5. pBABE-Tau-nYFP

   Plasmid

   #92204

   Purpose

   Retroviral overexpression vector for Tau bimolecular fluorescence complementation (BiFC)

   Depositor

   Huda Zoghbi

   Article

   Rousseaux et al Elife. 2016 Oct 25;5. pii: e19809. doi:

   Insert

   MAPT (MAPT Human)
   

   Use

   Retroviral

   Tags

   YFP(1-155)

   Expression

   Mammalian

   Mutation

   Promoter

   Available since

   Aug. 7, 2017

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

6. pAAV hSyn mCh-IRES-SspB(micro)-BoNT/B(147-441, Y365A)

   Plasmid

   #122986

   Purpose

   AAV plasmid with human synapsin promoter driving mCh and SspB(micro)-BoNT/B amino acids 147-441 separated with an IRES element. Co-express with BoNT/B(1-146)-iLID construct for PA-BoNT

   Depositor

   Matthew Kennedy

   Article

   Liu et al Neuron. 2019 Jan 15. pii: S0896-6273(19)

   Insert

   mCh-IRES-SspB(micro)-BoNT/B(147-441)
   

   Use

   AAV

   Tags

   mCh

   Expression

   Mammalian

   Mutation

   SspB contains R73Q "micro" mutation, Bo…

   Promoter

   human synapsin

   Available since

   March 20, 2019

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

7. pLVTHM-Bptf-sh28

   Plasmid

   #83278

   Purpose

   shRNA targeting BPTF

   Depositor

   Joe Landry

   Article

   Mayes et al Oncotarget. 2017 May 12;8(38):64344-6435

   Insert

   shRNA #28 to BPTF (BPTF, Bptf Human, Mouse)
   

   Use

   Lentiviral

   Tags

   Expression

   Mutation

   Promoter

   TRE-H1

   Available since

   Oct. 25, 2016

   Availability

   Industry, Academic Institutions, and Nonprofits

   

   Enlarge

8. pLVTHM-Bptf-sh5

   Plasmid

   #83277

   Purpose

   shRNA targeting BPTF

   Depositor

   Joe Landry

   Article

   Mayes et al Oncotarget. 2017 May 12;8(38):64344-6435

   Insert

   shRNA #5 to BPTF (BPTF, Bptf Human, Mouse)
   

   Use

   Lentiviral

   Tags

   Expression

   Mutation

   Promoter

   TRE-H1

   Available since

   Oct. 25, 2016

   Availability

   Industry, Academic Institutions, and Nonprofits

   

   Enlarge

9. pICE-EGFP-FLAG-TK1

   Plasmid

   #161919

   Purpose

   Expresses human TK1 with a N-terminal GFP-FLAG tag. Confers Puromycin resistance. Inducible in T-REx cells.

   Depositor

   Sébastien Britton

   Article

   Demange et al Elife. 2022 May 10;11. pii: 73913. doi:

   Insert

   Thymidine kinase, cytosolic (TK1 Human)
   

   Use

   Tags

   GFP-FLAG

   Expression

   Mammalian

   Mutation

   Promoter

   CMV

   Available since

   May 12, 2022

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

10. pSIREN-RetroQ-BPTF-sh3

    Plasmid

    #73667

    Purpose

    pSIREN-RetroQ vector containing shRNA sequence to BPTF

    Depositor

    Joe Landry

    Article

    Mayes et al Oncotarget. 2017 May 12;8(38):64344-6435

    Insert

    shRNA #3 to BPTF (BPTF, Bptf Human, Mouse)
    

    Use

    Retroviral

    Tags

    Expression

    Mutation

    Promoter

    Available since

    March 22, 2016

    Availability

    Industry, Academic Institutions, and Nonprofits

    

    Enlarge

11. pLV[Exp]-Bsd-CMV>hCDK11A

    Plasmid

    #239212

    Purpose

    Expresses CDK11A in mammalian cell lines

    Depositor

    Jason Sheltzer

    Article

    Julian et al bioRxiv 2025.08.03.668359; doi: https://

    Insert

    cyclin dependent kinase 11A (CDK11A Human)
    

    Use

    Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    Aug. 5, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

12. pE-N1-RDH11

    Plasmid

    #161916

    Purpose

    Expresses untagged human RDH11. Confers G418 resistance.

    Depositor

    Sébastien Britton

    Article

    Demange et al Elife. 2022 May 10;11. pii: 73913. doi:

    Insert

    Retinol dehydrogenase 11 (RDH11 Human)
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    CMV

    Available since

    May 12, 2022

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

13. pCAG-eSpCas9-2A-GFP-sgRNA-RDH11

    Plasmid

    #161924

    Purpose

    To generate RDH11 KO in human cells. Co-expresses eSpCas9(1.1), GFP and a guide RNA against RDH11 exon 2.

    Depositor

    Sébastien Britton

    Article

    Demange et al Elife. 2022 May 10;11. pii: 73913. doi:

    Insert

    sgRNA targeting RDH11 exon 2
    

    Use

    CRISPR

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    U6

    Available since

    May 12, 2022

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

14. pAAV uN2CpolyGly op GFP (NIID)

    Plasmid

    #224356

    Purpose

    Express GFP tagged upsteram ORF of NOTCH2NLC with an expansion (100x) of GGC repeats with codon optimization (NOT pure GGC repeats)

    Depositor

    Nicolas Charlet-Berguerand

    Article

    Boivin et al Neuron. 2021 Jun 2;109(11):1825-1835.e5.

    Insert

    uN2C with a GGC repeat expansion (100x)
    

    Use

    AAV

    Tags

    eGFP

    Expression

    Mammalian

    Mutation

    Codon-optimized for expression in human, so no pu…

    Promoter

    CMV + chimeric intron (CAG)

    Available since

    Feb. 5, 2025

    Availability

    Industry, Academic Institutions, and Nonprofits

    

    Enlarge

15. pEGFP-N1-HSD17B11-WT-FLAGC

    Plasmid

    #161903

    Purpose

    Expresses human HSD17B11 with a C-terminal FLAG-GFP tag. Confers G418 resistance.

    Depositor

    Sébastien Britton

    Article

    Demange et al Elife. 2022 May 10;11. pii: 73913. doi:

    Insert

    hydroxysteroid 17-beta dehydrogenase 11 (HSD17B11 Human)
    

    Use

    Tags

    FLAG-GFP

    Expression

    Mammalian

    Mutation

    Promoter

    CMV

    Available since

    May 12, 2022

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

16. pEGFP-N1-HSD17B13-WT-FLAGC

    Plasmid

    #184501

    Purpose

    Expresses human HSD17B13 with a C-terminal FLAG-GFP tag. Confers G418 resistance.

    Depositor

    Sébastien Britton

    Article

    Demange et al Elife. 2022 May 10;11. pii: 73913. doi:

    Insert

    17-beta-hydroxysteroid dehydrogenase 13 (HSD17B13 Human)
    

    Use

    Tags

    FLAGC-GFP

    Expression

    Mammalian

    Mutation

    Promoter

    CMV

    Available since

    June 28, 2022

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

17. pEGFP-C1-FLAG-BRAT1

    Plasmid

    #161920

    Purpose

    Expresses human BRAT1 with a N-terminal GFP-FLAG tag. Confers G418 resistance.

    Depositor

    Sébastien Britton

    Article

    Demange et al Elife. 2022 May 10;11. pii: 73913. doi:

    Insert

    BRCA1-associated ATM activator 1 (BRAT1 Human)
    

    Use

    Tags

    GFP-FLAG

    Expression

    Mammalian

    Mutation

    Promoter

    CMV

    Available since

    May 12, 2022

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

18. pEGFP-N1-HPGD-FLAGC

    Plasmid

    #161915

    Purpose

    Expresses human HPGD with a C-terminal FLAG-GFP tag. Confers G418 resistance.

    Depositor

    Sébastien Britton

    Article

    Demange et al Elife. 2022 May 10;11. pii: 73913. doi:

    Insert

    HPGD (HPGD Human)
    

    Use

    Tags

    FLAG-GFP

    Expression

    Mammalian

    Mutation

    Promoter

    CMV

    Available since

    May 12, 2022

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

19. pLV[Exp]-Neo-CMV>hCCNL2

    Plasmid

    #239219

    Purpose

    Expresses CCNL2 in mammalian cell lines

    Depositor

    Jason Sheltzer

    Article

    Julian et al bioRxiv 2025.08.03.668359; doi: https://

    Insert

    cyclin L2 (CCNL2 Human)
    

    Use

    Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    Aug. 5, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

20. pLV[Exp]-Bsd-CMV>hCDK11B

    Plasmid

    #239211

    Purpose

    Expresses CDK11B in mammalian cell lines

    Depositor

    Jason Sheltzer

    Article

    Julian et al bioRxiv 2025.08.03.668359; doi: https://

    Insert

    cyclin dependent kinase 11B (CDK11B Human)
    

    Use

    Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    Aug. 5, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge