We narrowed to 2,370 results for: mia

1. pCDH-3_Flag-TET1-S-WT

   Plasmid

   #232942

   Purpose

   Expresses short isoform of TET1 in mammalian cells in its wild-type form

   Depositor

   Jianjun Chen

   Article

   Chen et al Sci Transl Med. 2023 Mar 29;15(689):eabq

   Insert

   TET1-S-WT (TET1 Human)
   

   Use

   Lentiviral

   Tags

   Expression

   Mutation

   Promoter

   Available since

   May 19, 2025

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

2. KRD9_HBA1(HBA1reg-HBB)

   Plasmid

   #232402

   Purpose

   AAV production plasmid for HBA1 UTRs vector from Fig. 3 that mediates HDR at HBA1 locus using HBA1 sg5 gRNA. HBB gene includes introns; HBA1 UTRs flank HBA1 cassette. HAs are ~400bp each.

   Depositor

   Matthew Porteus, Kyle Cromer

   Article

   Cromer et al Nat Med. 2021 Apr;27(4):677-687. doi: 10

   Insert

   Hemoglobin Subunit Alpha 1 (HBA1 Human)
   

   Use

   AAV

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   Available since

   April 18, 2025

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

3. pCDH-3_Flag-TET1-S-MUT

   Plasmid

   #232943

   Purpose

   Expresses mutant form of the short isoform of TET1 in mammalian cells

   Depositor

   Jianjun Chen

   Article

   Chen et al Sci Transl Med. 2023 Mar 29;15(689):eabq

   Insert

   TET1-S-MUT (TET1 Human)
   

   Use

   Lentiviral

   Tags

   Expression

   Mutation

   H1652Y and D1654A

   Promoter

   Available since

   March 21, 2025

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

4. pCDH-no-Flag-TET1-S-WT

   Plasmid

   #232941

   Purpose

   Expresses short isoform of TET1 in mammalian cells in its wild-type form

   Depositor

   Jianjun Chen

   Article

   Chen et al Sci Transl Med. 2023 Mar 29;15(689):eabq

   Insert

   TET1-S-WT (TET1 Human)
   

   Use

   Lentiviral

   Tags

   Expression

   Mutation

   Promoter

   Available since

   March 21, 2025

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

5. KRD2_HBA1(HBA1reg-UbC-GFP)

   Plasmid

   #232401

   Purpose

   AAV production plasmid for HBA1 WGR vector from Fig. 1 that mediates HDR at HBA1 locus using HBA1 sg5 gRNA. HBA1 UTRs flank UbC-GFP cassette; GFP is followed by BGH polyA. HAs are ~400bp each.

   Depositor

   Matthew Porteus, Kyle Cromer

   Article

   Cromer et al Nat Med. 2021 Apr;27(4):677-687. doi: 10

   Insert

   Hemoglobin Subunit Alpha 1 (HBA1 Human)
   

   Use

   AAV

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   Available since

   Feb. 26, 2025

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

6. pKLV2.2-h7SKgRNA5(ARID1A(44))-hU6gRNA5(AAVS1)-PGKpuroBFP-W

   Plasmid

   #200506

   Purpose

   Lentiviral vector expressing gRNA targeting human ARID1A and AAVS1

   Depositor

   Kosuke Yusa

   Article

   Aoki et al Blood. 2023 Nov 3:blood.2023020857. doi:

   Insert

   ARID1A(44), AAVS1 (ARID1A, AAVS1 Human)
   

   Use

   Lentiviral

   Tags

   Expression

   Mutation

   Promoter

   Available since

   Jan. 18, 2024

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

7. pKLV2.2-h7SKgRNA5(SMARCA4(43))-hU6gRNA5(AAVS1)-PGKpuroBFP-W

   Plasmid

   #200503

   Purpose

   Lentiviral vector expressing gRNA targeting human SMARCA4 and AAVS1

   Depositor

   Kosuke Yusa

   Article

   Aoki et al Blood. 2023 Nov 3:blood.2023020857. doi:

   Insert

   SMARCA4(43), AAVS1 (SMARCA4, AAVS1 Human)
   

   Use

   Lentiviral

   Tags

   Expression

   Mutation

   Promoter

   Available since

   Jan. 17, 2024

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

8. pKLV2.2-h7SKgRNA5(SMARCA4(43))-hU6gRNA5(SMARCA2(47))-PGKpuroBFP-W

   Plasmid

   #200505

   Purpose

   Lentiviral vector expressing gRNA targeting human SMARCA4 and SMARCA2

   Depositor

   Kosuke Yusa

   Article

   Aoki et al Blood. 2023 Nov 3:blood.2023020857. doi:

   Insert

   SMARCA4(43), SMARCA2(47) (SMARCA4, SMARCA2 Human)
   

   Use

   Lentiviral

   Tags

   Expression

   Mutation

   Promoter

   Available since

   Jan. 9, 2024

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

9. pLX304_zeo_mmFbxw7(res)

   Plasmid

   #160106

   Purpose

   Expresses murine Fbxw7 alpha with a T199 silent mutation in mammalian cells. The T199 silent mutation confers resistance to the 5'-TGAACATGGTACAAGGCCAG-3' sgRNA

   Depositor

   Rizwan Haq

   Article

   Gstalder et al Cancer Discov. 2020 May 5. pii: 2159-829

   Insert

   Fbxw7alpha (Fbxw7 Mouse)
   

   Use

   Lentiviral

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   Available since

   Oct. 13, 2020

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

10. pLT3REVIR_MARK3 2573

    Plasmid

    #107233

    Purpose

    shRNA 2573. Do not use Evos or Acurri on these cells. Assess by FACS specifically with Venus and DsRed lazers. Tet-ON-all-in-one

    Depositor

    Alex Kentsis

    Article

    Brown et al Cancer Discov. 2018 Apr;8(4):478-497. do

    Insert

    MARK3 shRNA (22 nt) (MARK3 Human)
    

    Use

    Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    March 28, 2018

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

11. pLT3REVIR_MARK3 1122

    Plasmid

    #107232

    Purpose

    shRNA 1122. Do not use Evos or Acurri on these cells. Assess by FACS specifically with Venus and DsRed lazers. Tet-ON-all-in-one

    Depositor

    Alex Kentsis

    Article

    Brown et al Cancer Discov. 2018 Apr;8(4):478-497. do

    Insert

    MARK3 shRNA (22 nt) (MARK3 Human)
    

    Use

    Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    March 28, 2018

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

12. LVXN-Neo-NSD2-E1099K

    Plasmid

    #86011

    Purpose

    express NSD2 E1099K mutant in mammalian cells

    Depositor

    Darrin Stuart

    Article

    Jaffe et al Nat Genet. 2013 Nov;45(11):1386-91. doi:

    Insert

    NSD2 E1099K mutant (NSD2 Human)
    

    Use

    Tags

    Flag tag  D Y K D D D D K

    Expression

    Mammalian

    Mutation

    E1099K; K1002R (please see depositor comments bel…

    Promoter

    CMV

    Available since

    Jan. 13, 2017

    Availability

    Academic Institutions and Nonprofits only

13. pAMS823 His6-MBP-3C-ORF2p (238-1061, ORFeus-Hs) in pET41

    Plasmid

    #213024

    Purpose

    Expresses human LINE-1 ORF2p Core (238-1061) in E. coli as an N-MBP fusion

    Depositor

    Oliver Weichenrieder, Martin S. Taylor

    Article

    Baldwin et al Nature. 2024 Feb;626(7997):194-206. doi:

    Insert

    LINE-1 ORF2p (238-1061)
    

    Use

    Tags

    His6-MBP-3C

    Expression

    Bacterial

    Mutation

    Promoter

    T7 / Lac

    Available since

    May 6, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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14. BIC-Gag-DDX3

    Plasmid

    #233687

    Purpose

    Expresses a fusion between the Murine Leukemia Virus Gag polyprotein and the human DDX3 protein to produce virus-like particles loaded with DDX3 and deliver it to target cells.

    Depositor

    Emiliano Ricci

    Article

    Labaronne et al Nat Commun. 2025 Feb 18;16(1):1706. doi:

    Insert

    DEAD-box helicase 3 (DDX3X Human)
    

    Use

    Retroviral

    Tags

    Gag (Murine Leukemia Virus)

    Expression

    Mammalian

    Mutation

    Promoter

    hCMV

    Available since

    March 11, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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15. CCLMPC_HA-NUP98

    Plasmid

    #237482

    Purpose

    Express HA-tagged NUP98 in dual promoter lentiviral vector

    Depositor

    Charles Mullighan

    Article

    Michmerhuizen et al Cancer Discov. 2025 Jun 19. doi: 10.1158

    Insert

    HA-NUP98 (NUP98 Human)
    

    Use

    Lentiviral

    Tags

    HA

    Expression

    Mammalian

    Mutation

    Promoter

    MND/PGK

    Available since

    June 30, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

16. KRD22_HBA1(HBA1reg-HBB-longHAs)

    Plasmid

    #232403

    Purpose

    AAV production plasmid for HBA1 long HAs vector from Figs. 3-6 that mediates HDR at HBA1 locus using HBA1 sg5 gRNA. HBB gene includes introns; HBA1 UTRs flank full HBA1-2A-YFP cassette. HAs are ~900bp

    Depositor

    Matthew Porteus, Kyle Cromer

    Article

    Cromer et al Nat Med. 2021 Apr;27(4):677-687. doi: 10

    Inserts

    Hemoglobin Subunit Alpha 1 (HBA1 Human)
    Human Hemoglobin Subunit Beta (HBB Human)
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    April 18, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

17. pKLV2.2-h7SKgRNA5(ARID1A(44))-hU6gRNA5(ARID1B(21))-PGKpuroBFP-W

    Plasmid

    #200507

    Purpose

    Lentiviral vector expressing gRNA targeting human ARID1A and ARID1B

    Depositor

    Kosuke Yusa

    Article

    Aoki et al Blood. 2023 Nov 3:blood.2023020857. doi:

    Insert

    ARID1A(44), ARID1B(21) (ARID1A, ARID1B Human)
    

    Use

    Lentiviral

    Tags

    Expression

    Mutation

    Promoter

    Available since

    Jan. 18, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

18. pKLV2.2-h7SKgRNA5(ARID1A(44))-hU6gRNA5(ARID1B(23))-PGKpuroBFP-W

    Plasmid

    #200508

    Purpose

    Lentiviral vector expressing gRNA targeting human ARID1A and ARID1B

    Depositor

    Kosuke Yusa

    Article

    Aoki et al Blood. 2023 Nov 3:blood.2023020857. doi:

    Insert

    ARID1A(44), ARID1B(23) (ARID1A, ARID1B Human)
    

    Use

    Lentiviral

    Tags

    Expression

    Mutation

    Promoter

    Available since

    Jan. 18, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

19. pUC18_BCR_GUSB_e19a2

    Plasmid

    #190884

    Purpose

    molecular monitoring of atypical BCR::ABL1 fusion transcripts

    Depositor

    Nicholas Cross

    Article

    Schafer et al J Cancer Res Clin Oncol. 2021 Oct;147(10

    Inserts

    e19a2 BCR::ABL1 fusion cDNA
    GUSB cDNA (GUSB Human)
    BCR cDNA (BCR Human)
    

    Use

    Cloned cdna transcripts for use in rt-qpcr bcr::a…

    Tags

    Expression

    Mutation

    Promoter

    Available since

    Nov. 29, 2023

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

20. pUC18_BCR_GUSB_e6a2

    Plasmid

    #190882

    Purpose

    molecular monitoring of atypical BCR::ABL1 fusion transcripts (e6a2)

    Depositor

    Nicholas Cross

    Article

    Schafer et al J Cancer Res Clin Oncol. 2021 Oct;147(10

    Inserts

    e6a2 cDNA
    GUSB cDNA transcript (GUSB )
    BCR cDNA (BCR Human)
    

    Use

    Cloned cdna transcripts for use in rt-qpcr bcr::a…

    Tags

    Expression

    Mutation

    Promoter

    Available since

    Nov. 29, 2023

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge